A multi-institutional team has discovered a novel immune regulatory mechanism mediated by antibodies that selectively shut down overactive immune responses. The 'immune-induced TCR-like antibody' (iTab) can reduce disease severity and delay its onset in a mouse model of autoimmune disease.
SourceImmunology Frontier Research Center (IFReC) - The University of Osaka·JournalNature Communications·TypeExperimental study·DateApr 22, 2026
SAMSUNG T9 Portable SSD 2TB
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Researchers have identified a new immune function of human M cells, which can process and present gluten antigens, suggesting a potential link to celiac disease. This discovery sheds light on gut immunity and may support future research into celiac disease diagnosis or treatment.
SourceHubrecht Institute·JournalNature·TypeExperimental study·DateDec 10, 2025
Moffitt Cancer Center researchers have made a significant discovery about LAG3, a protein that suppresses the antitumor immune response. By understanding how LAG3 interacts with other proteins, they hope to develop more effective immune checkpoint inhibitors.
SourceH. Lee Moffitt Cancer Center & Research Institute·JournalNature·TypeExperimental study·DateSep 4, 2024
Researchers have developed a new organoid model to study the thymus and its function in training T cells. The model enables long-term culture of TECs, which could lead to new insights into treating patients with impaired thymus function.
SourceHubrecht Institute·JournalCell Reports·TypeExperimental study·DateApr 29, 2024
A new study found that the antibody-drug conjugate STRO-001 showed nanomolar cytotoxicity in 88% of cancer cell lines tested, with potent efficacy against proliferating B cells. The research supports ongoing clinical studies for patients with B-cell non-Hodgkin lymphoma.
SourceImpact Journals LLC·JournalOncotarget·TypeExperimental study·DateJan 17, 2023
Researchers have discovered an ancient category of MHC molecules, MHC-W, which represent a missing link for explaining how class I molecules evolved from a class II-like origin. This finding resolves a long-standing puzzle in immunogenetics.
SourceFujita Health University·JournalProceedings of the National Academy of Sciences·DateDec 13, 2021
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A study at University of Texas M.D. Anderson Cancer Center showed a potential new approach to treating follicular lymphoma and DLBCL through manipulation of molecular programs controlled by CREBBP. Inhibition of HDAC3 restores immune programs lost as a result of CREBBP mutations, paving the way for immunotherapy approaches.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalCancer Discovery·DateJan 8, 2020
Scientists have identified a novel infection route for influenza A viruses, utilizing MHC class II proteins to infect human and animal cells. This discovery raises questions about the risk of spill-over infections to other species and the evolutionary genesis of influenza viruses.
SourceUniversity of Freiburg·JournalNature·DateMar 4, 2019
A new study reveals that autophagy, a cellular process, enhances vaccine effectiveness by presenting antigens on MHC class II molecules to helper T cells. This process is more widespread than previously thought, affecting 50-80% of certain immune cells.
SourceRockefeller University·JournalImmunity·DateDec 22, 2006
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
The study reveals the role of Map in promoting S. aureus persistence and survival in infected mice by interfering with T cell function. Researchers warn that the increasing prevalence of multidrug-resistant strains poses a significant threat to public health.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateNov 19, 2002