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Chung-Ang University researchers use biomolecule-loaded metal-organic frameworks nanopatterns to aid artificial stem cell differentiation

A new platform mimics live cellular environment to guide stem cell differentiation outside the body. Researchers from Chung-Ang University developed a novel platform based on metal-organic frameworks, which offers advantages over conventional methods for in vitro stem cell differentiation.

SourceChung Ang University·JournalScience Advances·TypeExperimental study·DateJun 9, 2022

JCI early table of contents for Jan. 2, 2014

Studies in animal models reveal that mTOR activation contributes to morphine tolerance and hyperalgesia, while mitochondrial iron accumulation promotes doxorubicin-associated cardiotoxicity. These findings suggest potential therapeutic targets for improving pain management and limiting cardiotoxicity.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJan 2, 2014