Researchers at Columbia University School of Engineering and Applied Science have developed a novel cross-circulation platform that maintains the viability and function of donor lungs for several days. The technology, inspired by an abandoned surgical procedure from the 1960s, enables long-term support of living organs outside the body.
SourceColumbia University School of Engineering and Applied Science·JournalNature Biomedical Engineering·DateMar 6, 2017
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Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Researchers at Lund University successfully reprogrammed old blood stem cells to function like those of younger individuals, revealing a potential new approach to treating age-related diseases. This breakthrough suggests that epigenetic changes, rather than DNA mutations, underlie the decline in blood cell function with age.
SourceLund University·JournalNature Communications·DateFeb 23, 2017
Researchers have discovered a drug combination that can regenerate hair cells in the inner ear, offering a potential new way to treat hearing loss. The treatment involves expanding progenitor cells and stimulating them to become mature hair cells.
SourceMassachusetts Institute of Technology·JournalCell Reports·DateFeb 21, 2017
Scientists have successfully converted mouse alpha cells into insulin-producing beta cells by blocking the expression of two specific genes. The research suggests that this natural flexibility in cell fate may be exploited to develop a new therapeutic approach for Type 1 diabetes.
SourceStanford Medicine·JournalCell Metabolism·DateFeb 16, 2017
A University of East Anglia study reveals that the protein ninein is crucial for normal tissue development in the human gut. The research shows how microtubule rearrangements and the assembly of new Microtubule Organising Centres facilitate cell shape formation, nutrient uptake, and ultimately prevent cancer.
SourceUniversity of East Anglia·JournalOpen Biology·DateFeb 7, 2017
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers at Stanford University School of Medicine have developed a cheap and reusable diagnostic 'lab on a chip' with the help of an ordinary inkjet printer. The technology has the potential to enhance diagnostic capabilities around the world, especially in developing countries where access to early diagnostics is limited.
SourceStanford Medicine·JournalProceedings of the National Academy of Sciences·DateFeb 6, 2017
Scientists have identified antiviral T cells that can access HIV's germinal center hideouts using the CXCR5 molecule. These cells have stem cell-like properties and can infiltrate sites of ongoing viral replication, providing a potential target for therapeutic vaccines and HIV suppression.
SourceEmory Health Sciences·JournalProceedings of the National Academy of Sciences·DateJan 31, 2017
Researchers at Rice University have developed a new compound of bismuth and carbon nanotubes that improves upon existing cell-tracking agents. The improved Bi4C@US-tubes show up strongly on X-rays taken with computed tomography (CT) scanners, allowing for more efficient tracking of stem cells in the body.
SourceRice University·JournalACS Applied Materials & Interfaces·DateJan 30, 2017
Scientists have developed a method to observe gene editing in real-time, enabling the investigation of CRISPR-Cas9's biological processes and potential applications for treating genetic diseases such as sickle cell anemia and cystic fibrosis.
Researchers have mapped how plant cells determine size and adjust growth to achieve homogeneous cell sizes over time. This breakthrough overturns previous theories in the field, providing insights into factors determining plant size and fruit production.
SourceLund University·JournalProceedings of the National Academy of Sciences·DateJan 23, 2017
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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers discovered that immune cells use an active process to create gaps in blood vessel walls, involving the breakage of thin filaments and rapid reassembly. This process allows immune cells to squeeze through and survey organs for problems or join the fight against pathogens.
Researchers successfully used CRISPR-Cas9 technology to repair genetic mutations in blood stem cells of patients with chronic granulomatous disease, a rare and life-threatening disorder. The engineered cells maintained their gene edits long-term without side effects when implanted into mice.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience Translational Medicine·DateJan 11, 2017
Researchers have successfully generated epicardium cells using human stem cells and Wnt signaling pathway activation. The new method could potentially repair damaged heart tissue in patients who suffer from heart attacks, according to the study published in Nature Biomedical Engineering.
SourcePenn State·JournalNature Biomedical Engineering·DateJan 11, 2017
Researchers at Whitehead Institute have developed a gene pathway that enables the growth of brain organoids with surface folding, a key feature of human brain development. The study also shows potential for modeling Zika virus-caused microencephaly and identifying affected cells.
SourceWhitehead Institute for Biomedical Research·JournalCell Stem Cell·DateDec 29, 2016
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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers aim to remove senescent cells, which accumulate with age, to regrow hair, improve organ function and combat aging. However, hurdles include safety issues, off-target effects and high costs, limiting translation to humans.
SourceCell Press·JournalTrends in Molecular Medicine·DateDec 29, 2016
Researchers at Kyoto University found that the Myc gene regulates stem cell self-renewal in mice, leading to a slower rate of proliferation and impaired energy production. This discovery may lead to new treatments for infertility by stimulating sperm cell metabolism.
SourceKyoto University·JournalGenes & Development·DateDec 27, 2016
Researchers have developed synthetic stem cells that mimic natural cardiac stem cells, promoting tissue repair and reducing risks of tumor growth and immune rejection. These cells are more durable, can be used off-the-shelf, and can tolerate harsh freezing and thawing.
SourceNorth Carolina State University·JournalNature Communications·DateDec 26, 2016
A stem cell-based treatment, known as the Cell Bandage, has been trialled in humans and shown to repair damaged meniscus tissue, restoring full knee function. The trial received positive results, with three out of five patients retaining an intact meniscus after 24 months.
SourceUniversity of Liverpool·JournalStem Cells Translational Medicine·DateDec 15, 2016
Researchers discovered a single gene mutation causing two types of heart disease: one causes holes in infants' hearts, and the other leads to heart failure. The study revealed how the GATA4 gene's disruption affects cardiac development and muscle contraction.
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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers at the Krembil Research Institute have published a paper that challenges the prevailing view of vision recovery after retinal cell transplantation. They found that transplanted photoreceptor cells do not enter the recipient retina, contrary to previous interpretations.
SourceUniversity Health Network·JournalStem Cells·DateDec 14, 2016
A team of researchers from the University of Toronto has developed a proprietary peptide-hydrogel biomaterial that promotes skin cells to 'crawl' together, closing chronic, non-healing wounds caused by diabetes. The treatment closed wounds 200% faster than no treatment and 60% faster than existing collagen-based products.
SourceUniversity of Toronto Faculty of Applied Science & Engineering·JournalProceedings of the National Academy of Sciences·DateDec 14, 2016
Researchers developed a new heart imaging test that analyzes longitudinal strain to predict patient survival after stem cell transplant. The test outperformed conventional biomarkers and detected improvements before changes in traditional echocardiographic measures.
SourceBoston University School of Medicine·JournalEuropean Heart Journal - Cardiovascular Imaging·DateDec 12, 2016
Researchers at Duke University have identified a set of DNA-binding proteins in Arabidopsis roots that work together to trigger stem cell differentiation and create specialized cells with distinct roles. This discovery sheds light on the longstanding question of how plants make so many types of cells from the same genetic instructions.
SourceDuke University·JournalDevelopmental Cell·DateDec 6, 2016
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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers at Stanford University School of Medicine found that stem cells can police themselves to reduce scarring by producing a truncated version of a protein. This discovery holds promise for treating muscle diseases like muscular dystrophy and promoting healthy aging.
Researchers at MD Anderson Cancer Center identified a pathway by which cancer cells spread in the brain, opening up new possibilities for treatment. They found that the gene WNT5A enables glioma stem cells to transition into GdECs, leading to aggressive tumor growth and disease recurrence.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalCell·DateNov 17, 2016
Researchers at UCLA discovered that cardiac fibroblasts, which give rise to scar tissue after injury, can also produce bone-like cells. By blocking an enzyme involved in bone mineralization, they prevented calcification in mice, offering a potential new approach for treating abnormal calcium deposits in the heart.
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AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A recent study found that injury in schistosome parasites triggers stem cell growth, which restores aging tissue and aids the parasite's long-term survival. This discovery could lead to new ways to target these worms and improve our understanding of their infection mechanisms.
Researchers at VIB and Ghent University have uncovered a novel protein complex that controls plant tissue repair. This breakthrough could enable the efficient cultivation of crops and make them more resistant to parasites like those found in rice, wheat, and bananas.
SourceVIB (the Flanders Institute for Biotechnology)·JournalNature Plants·DateNov 2, 2016
Researchers at Hospital for Special Surgery have identified a population of stem cells called ADSCs that are reduced in number in the layer of fat sitting under the skin in patients with scleroderma. The study found that replenishing these cells with antibodies may reverse the fibrosis characteristic of the disease.
SourceHospital for Special Surgery·JournalJournal of Clinical Investigation·DateOct 31, 2016
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The study found that when mitochondria are disrupted, stem cells lose their ability to self-regenerate, but stressed cells initiate a growth program leading to tissue regeneration. This highlights the fundamental role of functioning mitochondria in regulating intestinal tissue renewal.
SourceTechnical University of Munich (TUM)·JournalNature Communications·DateOct 27, 2016
Researchers have developed an innovative skin graft process that combines split thickness skin grafts with a specially engineered sheet of stem cells to maximize natural healing power. The new technique shows promising results in treating large or complicated burn injuries, preserving hair follicles and oil glands.
SourceMichigan Technological University·JournalTheranostics·DateOct 27, 2016
A study found that corneal cells' softness indicates their potential for stem-like activity, enabling rapid and cost-effective enrichment of limbal stem cells. This biomarker could improve clinical success rates for corneal transplant patients with naturally low limbal stem cell percentages.
SourceCell Press·JournalBiophysical Journal·DateOct 18, 2016
Researchers discovered that leukemia cells don't hide in specific niches but instead move actively throughout the bone marrow. This movement may help them survive treatment and evade targeted therapies.
SourceImperial College London·JournalNature·DateOct 17, 2016
Researchers found that increasing satellite cell numbers can increase muscle regeneration and stifle degeneration. Muscles with genetically modified TEAD1-expressing fibers showed a six-fold increase in satellite cells, allowing for faster repair after injury.
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Researchers used ECIS to track stem cell transformation into bone tissue cells, revealing age-related differences in conversion rates and calcium secretion. The study provides new insights into the potential of adipose-derived stem cells for osteoporosis treatment.
SourceUniversity of Missouri-Columbia·JournalStem Cells Translational Medicine·DateOct 5, 2016
Developing blood cells are caught in fluctuating multi-lineage states before becoming specific cell types, according to a study published in Nature. The research team found that dynamic instability and counteracting gene networks induce mixed-lineage states necessary for cell-type specification.
SourceCincinnati Children's Hospital Medical Center·JournalNature·DateAug 31, 2016
Researchers developed an algorithm to analyze single-cell sequencing data, revealing the genetic control of blood cell formation. The 'diffusion pseudotime' method orders cells on a virtual timeline, reconstructing developmental paths and gene expression sequences.
SourceHelmholtz Munich (Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH))·JournalNature Methods·DateAug 31, 2016
A study by Purdue University researchers reveals that overactive Notch signaling can drive the formation of cancerous fatty tumors, while normal signaling is required for healthy cell differentiation. The findings suggest a potential new approach for treating a subtype of liposarcomas and other metabolic conditions.
SourcePurdue University·JournalJournal of Experimental Medicine·DateAug 31, 2016
Researchers successfully cultured norovirus in human intestinal cells, a breakthrough that could lead to the development of novel therapeutics and vaccines against this debilitating virus. The study, supported by the National Institute of Allergy and Infectious Diseases, sheds light on the molecular mechanisms behind norovirus infection.
SourceNIH/National Institute of Allergy and Infectious Diseases·JournalScience·DateAug 25, 2016
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GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A clinical trial has shown that metformin can promote a patient's ability to repair their own damaged blood vessels by increasing vascular stem cells. This could lead to improved treatment options for Type 1 diabetes patients at risk of developing heart disease.
SourceNewcastle University·JournalCardiovascular Diabetology·DateAug 25, 2016
Fascin protein plays a crucial role in deforming the cell nucleus to navigate through tight spaces. The study suggests that this ability may be exploited by cancer cells to invade tissues, making fascin a potential target for therapy.
A novel imaging technique allows visualization and monitoring of structural alterations in neuronal networks after traumatic brain damage, stroke, or aging processes. This enables detection and characterization of diseases like dementia, epilepsy, and metabolic disorders.
SourceLudwig-Maximilians-Universität München·JournalNature Methods·DateAug 22, 2016
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Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers at TSRI have made a breakthrough in treating aqueous deficiency dry eye (ADDE), also known as painful blindness, by injecting regenerative progenitor cells into the lacrimal gland. The treatment shows significant promise in restoring tear production and repairing damaged gland tissue.
SourceScripps Research Institute·JournalStem Cells Translational Medicine·DateAug 18, 2016
A new regenerative bandage heals diabetic foot ulcers faster and promotes healing without cancer risk, according to Northwestern University researchers. The bandage delivers a protein that recruits stem cells and creates new blood vessels, improving wound repair.
SourceNorthwestern University·JournalJournal of Controlled Release·DateAug 16, 2016
Researchers identified new mechanisms controlling stem cell properties in flatworms, including alternative splicing processes that operate only in stem cells. The study also reveals a previously unknown interaction between proteins MBNL and CELF, which may have implications for human regenerative medicine.
SourceMax Delbrück Center for Molecular Medicine in the Helmholtz Association·DateAug 9, 2016
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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Researchers at ETH Zurich study how stem cells differentiate into blood cells, revealing complex mechanisms beyond previously thought protein GATA1 and PU.1 roles. This knowledge is vital for developing effective treatments for life-threatening diseases.
Researchers found that a non-surgical treatment using patient's own bone marrow stem cells improved symptoms and increased physical activity in patients with angina. The treatment involved injecting a 'catalyst' molecule to stimulate stem cell migration into the bloodstream, followed by re-injection of harvested stem cells.
Researchers have discovered that protein pairs are essential for cellular memory, allowing cells to store and recall information. The formation of these pairs enables cells to respond more quickly to environmental stimuli and differentiate into specialized cells.
SourceUniversity of Basel·JournalCell Reports·DateJul 15, 2016
Researchers discovered that protein pairs form feedback loops to store information in a cell's memory. The formation of these pairs is crucial for the cell's sensitivity to environmental stimuli and its ability to differentiate into specialized cells.
SourceUniversity of Basel·JournalCell Reports·DateJul 14, 2016
Researchers discovered that bacteria divide asymmetrically when exposed to stress, accumulating defects in some individuals while others remain young and healthy. This collective behavior allows the bacterial colony to stay young, produce more offspring, and maintain overall health.
SourceUniversity of Copenhagen - Niels Bohr Institute·JournalCell Systems·DateJul 14, 2016
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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Scientists use iDISCO clearing method to visualize brain tissue from deceased patients with Alzheimer's disease, exposing nonrandom structures of beta amyloid plaques. This breakthrough finding may lead to new targeted drugs and a better understanding of the relationship between plaque presence and disease severity.
Researchers have discovered at least four separate subtypes of human insulin-producing beta cells, which could lead to a better understanding of the disease process and the development of new treatments for type 2 diabetes. The study found that these cell subtypes produce different amounts of insulin and may regenerate at varying rates.
SourceOregon Health & Science University·JournalNature Communications·DateJul 11, 2016
Researchers at UC Santa Barbara have identified a new type of filament-forming protein in fruit flies that shares similarities with intermediate filaments in human cells. This discovery may provide insights into how insects survive without traditional IF proteins.
SourceUniversity of California - Santa Barbara·JournalCell Reports·DateJul 7, 2016
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A new government study suggests that the graying of the biomedical workforce is driving younger scientists away from academia, but found no evidence of a preference for older applicants in NIH grant funding. The study's authors conclude that other factors, such as changes in academic training and payment, are more likely to be contribu...
Scientists at the Buck Institute used a naturally occurring anti-inflammatory factor called MANF to promote tissue repair and regenerative success in the retina of mice. The discovery holds promise for treating chronic inflammatory diseases of the eye, including macular degeneration.
SourceBuck Institute for Research on Aging·JournalScience·DateJun 30, 2016
Researchers are studying exercise's effects on muscle loss and weakness in people with chronic kidney disease, a condition affecting 20 million Americans. They aim to determine the optimal dose of exercise and explore whether it can mitigate disease progression.
Researchers at the University of Bristol have developed a new bio-ink containing stem cells that can be printed using 3D technology. The bio-ink allows for the creation of complex living tissue structures with microscopic pores, providing effective nutrient access for stem cells.
SourceUniversity of Bristol·JournalAdvanced Healthcare Materials·DateJun 23, 2016
Research at Washington University School of Medicine found that a metabolite produced by beneficial gut microbes restricts the proliferation of intestinal stem cells. This limits the intestine's ability to repair itself after injury or damage, potentially hampering treatment for inflammatory bowel disease (IBD).
Rigol DP832 Triple-Output Bench Power Supply
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Researchers at Oxford University have identified the oldest known population of plant root stem cells, preserved in a 320 million-year-old fossil. These ancient stem cells provide unique insights into the evolution of roots and their role in shaping the Earth's climate.
SourceUniversity of Oxford·JournalCurrent Biology·DateJun 2, 2016
A new approach repairs liver disease by converting fibrosis-causing cells into functional hepatocytes, reducing damage and improving liver function. The technique targets liver fibrosis, a primary driver of liver disease, and may be more efficient than cell transplants.
SourceUniversity of California - San Francisco·JournalCell Stem Cell·DateJun 2, 2016