A study by Philipp Maass and Anja Weise found that chromosomes 12 and 17 frequently interact with each other across different individuals, resulting in recurrent patterns. This interaction is linked to a human genetic condition, brachydactyly, where the deletion of a specific gene alters chromosomal arrangements and disturbs interactions.
SourceMax Delbrück Center for Molecular Medicine in the Helmholtz Association·JournalThe EMBO Journal·DateJun 20, 2018
Researchers used single-cell transcriptomics to characterize stromal cells in fat tissue and discovered a subpopulation called Aregs that suppresses adipogenesis. These findings provide potential new avenues for treating metabolic diseases like type-2 diabetes.
SourceEcole Polytechnique Fédérale de Lausanne·JournalNature·DateJun 20, 2018
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers at Tampere University used artificial intelligence and machine learning to differentiate between genetic cardiac diseases from healthy cells. The study successfully identified specific features in cardiomyocyte beating behavior, enabling accurate diagnosis.
SourceTampere University·JournalScientific Reports·DateJun 19, 2018
Researchers successfully restored cartilage tissue and eliminated pain syndrome in a patient using cell technology-based regenerative medicine. This treatment promises to prolong the lives of natural joints by addressing limited regenerative potential of knee cartilage injuries.
SourceKazan Federal University·JournalFrontiers in Medicine·DateJun 18, 2018
Researchers used periodontal ligament-derived stem cells to create a cell sheet that promoted the formation of both cementum- and PDL-like tissue in dogs. This innovative work combines traditional dental implants with stem cell sheet technology, offering a promising solution for widespread dental health care issues.
SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalTissue Engineering·DateJun 13, 2018
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
In certain fish and frogs, cellular umbrellas shade fragile stem cells from the sun's harmful rays. This discovery highlights an important tool some aquatic animals use to keep crucial blood-cell-producing stem cells safe.
SourceHoward Hughes Medical Institute·JournalNature·DateJun 13, 2018
Researchers at Harvard University have discovered that the 'blood stem cell niche' evolved to protect blood stem cells from ultraviolet (UV) rays in sunlight. This finding has significant implications for improving the safety of blood stem cell transplants, a procedure used to treat patients with blood diseases and cancers.
USC researchers have discovered that the precise arrival of progenitor cells determines their form and function in the kidney. The study advances understanding of how to assemble building blocks to fashion kidney tissue, which can lead to breakthroughs in drug development and organ transplantation.
SourceUniversity of Southern California·JournalDevelopmental Cell·DateJun 4, 2018
Scientists at Newcastle University successfully printed the first human corneas using a unique gel-like substance and 3D printing technology. The breakthrough could provide an unlimited supply of corneas for transplantation, addressing a significant shortage that affects millions worldwide.
SourceNewcastle University·JournalExperimental Eye Research·DateMay 29, 2018
Researchers have engineered a cell-like structure that harnesses photosynthesis to perform metabolic reactions, including energy harvesting and cytoskeleton formation. This innovation opens up new possibilities for building artificial cells that can mimic complex biological behaviors.
SourceHarvard John A. Paulson School of Engineering and Applied Sciences·JournalNature Biotechnology·DateMay 29, 2018
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A special section in Perspectives in Biology and Medicine examines the newest and most complex issues surrounding stem cells. The issue includes essays on the potential impacts of using a person's own stem cells on patients, health-care systems, and the public trust in science and medicine.
SourceJohns Hopkins Medicine·JournalPerspectives in Biology and Medicine·DateMay 22, 2018
Recent studies suggest tRNAs and tRNA fragments are involved in cellular processes associated with diseases such as cancer, viral infections, and neurodegenerative disorders. Dr. Todd Lowe's lab is characterizing all 500 human tRNA genes to determine their roles in the cell.
SourceUniversity of California - Santa Cruz·DateMay 17, 2018
Crowdfunding campaigns for unproven stem cell interventions often convey misleading information about treatment efficacy and risks. The study analyzed 408 campaigns, finding that 44% made definitive claims, while 36 mentions of low-risk interventions were reported.
Researchers discovered a connection between genes controlling hair color and innate immune response in mice. Gray hair is associated with activation of the innate immune system, which produces signaling molecules to fight off viruses and bacteria.
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
Researchers tracked 27 patients for five years after receiving purified CD34+ cell therapy, showing improved pain management and limb salvage. The study suggests a potential new cell therapy for debilitating disease.
SourceWiley·JournalStem Cells Translational Medicine·DateMay 1, 2018
Researchers have developed a new way to introduce molecules and therapeutic genes into human cells using ultrafast compression, which can improve cell transfection efficiency. The technique involves compressing cells in microfluidic devices, causing them to take up surrounding fluid and macromolecules.
SourceGeorgia Institute of Technology·JournalMaterials Today·DateApr 30, 2018
Salk Institute researchers have generated aggressive glioblastoma multiforme tumors in human cerebral organoids using CRISPR-Cas9 tool. The new model could be used to study tumor progression, investigate new drugs or personalize treatments for patients.
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Gene editing of bone marrow stem cells has shown promise against HIV in non-human primates. The technique successfully reduced the size of dormant 'viral reservoirs' that pose a risk of reactivation, giving rise to white blood cells resistant to SHIV.
Researchers at Stockholm University discovered a new mechanism regulating stem cells in the fruit fly's intestine and found that a specific protein can slow tumour growth. The study sheds light on how intestinal diseases occur and may contribute to the development of new medicine to prevent and cure them.
SourceStockholm University·JournalStem Cell Reports·DateApr 19, 2018
Researchers at University of Sydney establish method to identify individual extracellular vesicles (EVs) using resonance-enhanced atomic force microscope infrared spectroscopy. This allows for biomarkers for diverse diseases such as cancers, cardiovascular, kidney and liver disease, dementia, and multiple sclerosis.
SourceUniversity of Sydney·JournalNanoscale Horizons·DateApr 12, 2018
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Researchers at UCLA have identified four distinct subtypes of melanoma with varying levels of sensitivity to ferroptosis, a type of self-inflicted cell death. These findings suggest new treatment approaches for dedifferentiated melanomas by combining ferroptosis-inducing drugs with multiple cancer therapies.
SourceUniversity of California - Los Angeles Health Sciences·JournalCancer Cell·DateApr 12, 2018
Researchers have identified tuft cells as the primary target of norovirus infection, a discovery that could pave the way for new treatments. The study found that administering immune signaling proteins IL-4 and IL-25 increased viral transmission and abundance in mice.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateApr 12, 2018
Researchers at the University of Iowa have discovered glandular myoepithelial cells that can regenerate airways after severe injury. These reserve stem cells can develop into new replacement cells in both submucosal glands and the lining of the airway, offering a potential therapeutic target for lung diseases.
SourceUniversity of Iowa Health Care·JournalCell Stem Cell·DateApr 12, 2018
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
A team of computational biologists developed an algorithm to integrate multiple sequencing datasets at single-cell resolution. This approach enables the comparison of single-cell datasets and dissects differences between them.
SourceNew York University·JournalNature Biotechnology·DateApr 2, 2018
Researchers from Moscow State University discovered the structure of a key region of the telomerase enzyme, which plays a crucial role in cellular aging and DNA replication. The study's findings have significant implications for developing potential anticancer drugs and understanding the regulation of telomerase activity.
SourceLomonosov Moscow State University·JournalNucleic Acids Research·DateMar 22, 2018
A team of plant geneticists at Cold Spring Harbor Laboratory identified a protein receptor on stem cells that issues different instructions depending on the peptide fragment activating it. This multi-functional receptor has important implications for boosting crop yields, particularly in crops like corn and rice.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers created a 3D bioengineered tooth bud model using Gelatin Methacrylate (GelMA) hydrogel and postnatal dental stem cells. Decellularized tooth bud extracellular matrix (dTB ECM) was introduced to enhance dental stem cell differentiation, resulting in whole tooth structures upon in vivo implantation
SourceInternational Association for Dental, Oral, and Craniofacial Research·JournalJournal of Dental Research·DateMar 21, 2018
A new study suggests that low-calorie sweeteners can promote metabolic syndrome and increase the risk of prediabetes and diabetes in overweight individuals. The research found that these substances can lead to increased glucose entry into cells through enhanced activity of genes called glucose transporters.
Researchers at University of Illinois Chicago developed chimeric cells that can restore the structural muscle protein dystrophin in people with Duchenne muscular dystrophy, potentially avoiding the need for immunosuppressive drugs.
SourceUniversity of Illinois Chicago·JournalStem Cell Reviews and Reports·DateMar 16, 2018
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers at UCLA have created a new method for targeted gene delivery using 'nanospears,' which can enable safer, faster and more cost-effective gene therapies. The nanostructures are biodegradable and can be mass-produced inexpensively, delivering genetic information with minimal impact on cell viability and metabolism.
SourceUniversity of California - Los Angeles Health Sciences·JournalACS Nano·DateMar 14, 2018
Researchers at BWH discovered that cell sex influences nanoparticle uptake, response to reprogramming techniques, and paracrine factors. These findings may help develop sex-specific nanomedicines for targeted drug delivery applications.
SourceBrigham and Women's Hospital·JournalACS Nano·DateMar 14, 2018
Researchers have developed a method to create large amounts of fillable and targeted nanovesicles using immune cells. These nanovesicles can be customized with specific ligands to target different types of tumors, enabling more effective cancer treatment.
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers have identified a lung stem cell that repairs the organ's gas exchange compartment and restores respiratory function after severe influenza and other respiratory ailments. The discovery provides new insights into lung regeneration and identifies novel genetic and epigenetic pathways important for lung regeneration.
SourceUniversity of Pennsylvania School of Medicine·JournalNature·DateFeb 28, 2018
Researchers found that S597 slows progression of atherosclerosis in mice with metabolic syndrome by reducing inflammation and immune cell activity. The peptide lowers blood sugar levels without preventing atherosclerosis, offering a novel treatment strategy for protecting against advanced cardiovascular disease.
SourceUniversity of Washington School of Medicine/UW Medicine·JournalDiabetes·DateFeb 26, 2018
A University of Guelph study found that cardiolipin helps prevent protein misfolding in Parkinson's disease, leading to nerve cell death. Researchers believe cardiolipin may represent a new target for developing therapies to slow the progression of the disease.
SourceUniversity of Guelph·JournalNature Communications·DateFeb 26, 2018
Researchers at Karolinska Institutet discover high number of mutations in muscle stem cells impairing cell regeneration, which may result in new medication for building stronger muscles. The study found that physical exercise could clear out cells with many mutations.
SourceKarolinska Institutet·JournalNature Communications·DateFeb 23, 2018
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A new study examines the evolutionary dynamics of cancer development in Barrett's Esophagus patients, revealing influences that lead some cells to remain stable while others become cancerous. The research provides insights into the genetic and chromosomal variations that predict progression to esophageal adenocarcinoma.
SourceArizona State University·JournalNature Communications·DateFeb 23, 2018
A new study shows that injecting cardiac progenitor cells can reverse fatal heart disease caused by Duchenne muscular dystrophy, while also improving limb strength and movement ability. Exosomes secreted by the injected cells unexpectedly restore muscle function in a mouse model of muscular dystrophy.
SourceCedars-Sinai Medical Center·JournalStem Cell Reports·DateFeb 22, 2018
Researchers found that mature cells in different organs activate the same genes and undergo similar processes when dividing again, leading to potential new targets for cancer treatment. This discovery could support using universal strategies to treat or prevent cancer in various organs.
SourceWashU Medicine·JournalThe EMBO Journal·DateFeb 21, 2018
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Scientists at Rice University have successfully used CRISPR/Cas9-based gene editing to repair 20-40% of stem and progenitor cells from patients with sickle cell disease. The study, led by bioengineer Gang Bao, aims to find a cure for the hereditary disease.
Researchers at Queen Mary University of London have discovered that cells can 'walk' on liquids using protein nanosheets with strong mechanical properties. This breakthrough could lead to the design of new cell technologies for regenerative medicine and tissue engineering.
SourceQueen Mary University of London·JournalNano Letters·DateFeb 14, 2018
Researchers at the University of York have identified a potential link between altered sugar chains and enhanced bone formation in stem cells. By treating cells with a chemical that modifies sugar chains, they found improved bone growth processes, which could pave the way for new osteoporosis treatments.
SourceUniversity of York·JournalJournal of Cell Science·DateFeb 14, 2018
PanTHERA CryoSolutions has discovered a small molecule inhibitor that prevents ice recrystallization, a process causing cell death and damage when freezing cells and tissues. This technology results in faster engraftment and increased incidence of engraftment for clinical settings.
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Scientists at CRAG have found that plant cells know when to stop growing by detecting their size, allowing for coordinated division, elongation, and differentiation. This process is also linked to the effect of steroid hormones, such as brassinosteroids, on root growth.
SourceCentre for Research in Agricultural Genomics (CRAG)·JournalMolecular Systems Biology·DateJan 29, 2018
Scientists have discovered a protein called Setd7 that regulates stem cell growth and differentiation. Inhibiting this protein allows stem cells to remain undifferentiated, facilitating tissue regeneration and improved muscle function.
SourceUniversity of British Columbia·JournalCell Stem Cell·DateJan 25, 2018
Researchers at Howard Hughes Medical Institute have developed a synthetic version of the plant hormone auxin and an engineered receptor to recognize it, enabling precise control over plant growth and development. This breakthrough system, called
SourceHoward Hughes Medical Institute·JournalNature Chemical Biology·DateJan 22, 2018
Scientists have created new tiny tubes that can help with water filtration and tissue engineering studies. The tubes are inspired by protein structures called microtubules found in cells and are thousands of times smaller than a human hair.
SourceDOE/Pacific Northwest National Laboratory·JournalNature Communications·DateJan 18, 2018
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers suggest a biological innovation fueled animal diversification during the Cambrian explosion, rather than atmospheric oxygen changes. Tumor biology insights reveal how stem cells maintain properties in high-oxygen environments, sparking new perspective on tissue renewal.
SourceUniversity of Southern Denmark·JournalNature Ecology & Evolution·DateJan 18, 2018
A novel hypothesis proposes that animal diversification resulted from a revolution within the animals' own biology, rather than in surrounding chemistry. Cells with stem cell properties are vital for multicellular life, and tumor cells have developed mechanisms to maintain these properties despite high oxygen levels.
SourceLund University·JournalNature Ecology & Evolution·DateJan 18, 2018
Researchers at Radboud University Medical Center discovered that mevalonate, a byproduct of cholesterol production, trains the immune system. A Western diet rich in cholesterol can also induce trained immune cells, leading to long-lasting inflammation. Statins may inhibit this training, while boosting it could help weakened immune systems
SourceRadboud University Nijmegen·JournalCell·DateJan 11, 2018
A team of Canadian researchers has discovered a way to re-program innate immune cells to kill tuberculosis. The innovative work aims to make vaccines more effective against TB and other infectious diseases like the flu. By targeting stem cells in the bone marrow, scientists were able to boost the killing efficiency of macrophages.
Researchers have identified a key gene, Ufbp1, that helps maintain healthy Paneth cells in the small intestine, which are essential for a balanced gut microbiome. The study found that when this gene is knocked out, Paneth cells die and good bacteria levels decrease, leading to inflammatory bowel disease.
SourceMedical College of Georgia at Augusta University·DateJan 10, 2018
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A gene therapy approach using AAV vectors reprograms alpha cells into functional insulin-producing beta cells, restoring normal blood glucose levels for an extended period. The strategy shows promise for treating autoimmune diabetes without immunosuppression.
A new removable implant has been developed to control type 1 diabetes, with hundreds of thousands of islet cells protected by a thin hydrogel coating and attached to a polymer thread. This therapy could replace daily insulin injections and offer a more effective management solution for the disease.
SourceCornell University·JournalProceedings of the National Academy of Sciences·DateJan 2, 2018
A study by Imperial College London has discovered that a drug used to treat iron overload can protect bone marrow areas and allow blood stem cells to survive. This can improve the efficiency of chemotherapy, increasing the five-year survival rate for AML patients over 60 to 5-15 per cent.
SourceImperial College London·JournalCell Stem Cell·DateDec 21, 2017
Scientists show that transplanted muscle cells loaded with magnetic nanoparticles engraft better onto the existing tissue, leading to improved heart function. The technology could potentially be used to revitalize damaged heart tissue and has shown promising results in mice.
SourceUniversity of Bonn·JournalBiomaterials·DateDec 1, 2017
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
Researchers found that patients with high levels of indoleamine 2,3 dioxygenase (IDO) at diagnosis have lower overall survival rates and early mortality. IDO expression should routinely be measured during bone marrow biopsies to identify potential treatment targets.
SourceMedical College of Georgia at Augusta University·JournalScientific Reports·DateNov 27, 2017
Research at Lund University found that HLF gene's failure to shut down leads to inadequate lymphocyte development, resulting in a single type of immune defense. The study aimed to identify mechanisms for breaking down leukemia, an aggressive blood cancer with poor prognosis.
Researchers found that cell cycle proteins are crucial for releasing neutrophil extracellular traps (NETs) in immune cells. This process helps to contain and eliminate fungal infections in mice and human cells.
Researchers at Boston Children's Hospital have successfully reversed type 1 diabetes in a mouse model by infusing pre-treated blood stem cells. The treated cells curbed the autoimmune reaction and reversed hyperglycemia in diabetic mice, with almost all mice cured of diabetes in the short term and one third maintaining normal blood sug...
SourceBoston Children's Hospital·JournalScience Translational Medicine·DateNov 15, 2017
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.