Articles tagged with Tissue Samples
Researchers used post-mortem spinal cord tissue to identify a unique gene expression profile in ALS patients, revealing distinct changes underlying the terminal stages of the disease. The study distinguishes between familial and sporadic ALS forms, providing insights into the molecular pathophysiology of neurodegeneration.
Researchers at USAMRIID successfully detected variola virus in a 50-year-old tissue sample using integrated diagnostic methods. The study demonstrates the capabilities of modern molecular diagnostics in identifying biological agents, which is crucial for national defense and infectious disease research.
A new pathway has been discovered at Stanford that provides insight into heart disease, with apelin-APJ signaling potentially holding key to treatment for heart failure. The study used microarrays to scan thousands of genes and found a previously unnoticed connection between apelin and APJ receptors.
Researchers developed a new method to detect melanoma in lymph nodes using molecular analysis, revealing 25% of cancer-free patients had undetectable metastases. The study found patients with multiple markers were more likely to develop recurrence and die from the disease.
A new microdialysis probe can detect cytokine markers indicating early infection or rejection responses to implants. This detection method aims to bioengineer the site for optimal device performance, ultimately benefiting public health and economic development.
Researchers used banded water snakes to compare traditional testing methods with nonlethal samples, finding promise in laser ablation for conservation-minded eco-toxicological studies. The study was conducted at SREL on the Savannah River Site, partially funded by a grant from DOE.
Researchers are investigating the role of arterial stiffness in hypertension by analyzing the elasticity, strength, and stiffness of rat and calf arteries. They found that hypertensive tissues are stiffer and less responsive to pressure changes.
Researchers have created a new x-ray technique called DEI that enables the visualization of soft tissues such as skin, cartilage, and blood vessels. This technique has potential applications in diagnosis and could enhance mammography and the detection of other soft tissue pathologies.
Researchers at Vanderbilt University Medical Center found that COX-1, not COX-2, is expressed in epithelial ovarian cancer tissue samples. This discovery may lead to the development of new treatments for ovarian cancer by blocking both COX-1 and COX-2.
Dr. Babs Soller's team is working on a sensor system that can measure blood and tissue chemistry without the need for blood draws or incisions, providing accurate readings unaffected by skin color or body fat. The device has potential applications in space medicine, emergency rooms, ambulances, and exercise training.
Researchers identified a novel gene, mammaglobin (MG), expressed only in breast cancer tissue. MG was found to be present in 81% of breast cancers and has potential applications for early detection and identification of metastases.
Researchers at MIT have created a biodegradable polymer called biorubber that can stretch and snap back into shape, mimicking the elasticity of human organs. This breakthrough material has potential applications in tissue engineering, including heart tissue, blood vessels, and whole organs for transplantation.
A new genetic testing service using quantitative fluorescence PCR has been implemented in the UK NHS, providing rapid diagnosis of fetal genetic abnormalities. The service has shown high accuracy and efficiency, with all tested samples yielding results within 1.25 working days.
A recent study found that female great white sharks tend to stay in a particular region, while males disperse widely across ocean basins. This discovery has significant conservation implications for managing the species' populations and breeding grounds.
A new study at Ohio State University found that using an extended sector biopsy technique can detect cancer in 13.5% more men than traditional methods. The additional tissue samples improved the accuracy of prostate cancer diagnoses, particularly for cancers detected inside the gland.