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Golden Gate method enables rapid, fully-synthetic engineering of therapeutically relevant bacteriophages

Researchers from New England Biolabs and Yale University have developed a first fully synthetic bacteriophage engineering system using the High-Complexity Golden Gate Assembly platform. This method simplifies strain engineering techniques, allowing for rapid creation of tailored therapeutic strains to overcome antibiotic resistance.

SourceNew England Biolabs·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJan 19, 2026

Coconut tree cloning breakthrough will help propagation and preservation

Scientists at KU Leuven developed a method to multiply coconut trees faster and store them more efficiently, preserving genetic diversity and meeting the demand for coconuts. The technique allows thousands of new specimens with the same genetic profile to be obtained, offering potential for coconut plantations worldwide.

SourceKU Leuven·JournalScientific Reports·TypeExperimental study·DateSep 15, 2021

Powerful new technique can clone thousands of genes at once

Scientists have developed a powerful new technique called LASSO cloning that can clone thousands of long DNA sequences at once, speeding up the creation of proteins and discovery of new medicines. This innovation enables researchers to analyze what genes' proteins do, leading to potential breakthroughs in scores of diseases.

SourceJohns Hopkins Medicine·JournalNature Biomedical Engineering·DateJul 5, 2017

Mapping the maize genome

Researchers have developed a detailed positional cloning protocol to locate genes within the large and complex maize genome. This technique allows for the identification of genetic markers linked to specific traits, enabling precise localization of candidate regions until the gene is identified.

SourceBotanical Society of America·JournalApplications in Plant Sciences·DateJan 20, 2015

Japanese researchers succeed in making generations of mouse clones

Researchers at RIKEN Center for Developmental Biology successfully cloned mice multiple times using somatic cell nuclear transfer (SCNT) technique, overcoming previous limitations. The study published in Cell Stem Cell reveals no accumulation of genetic or epigenetic abnormalities after repeated cloning.

SourceRIKEN·JournalCell Stem Cell·DateMar 7, 2013