Articles tagged with Dna Methylation
Researchers found that plants inherit traits from factors outside of genes, such as DNA modification and packaging, which can be passed on to offspring. The study suggests a cost of resistance in plants, where hyperactive defense systems lead to physical damage despite low disease threat.
A recent discovery by Dr. Kathrin Muegge and colleagues has revealed that a protein called Lsh is required for normal genome-wide methylation during development. The study suggests that chromatin structure plays a crucial role in regulating DNA methylation, which is essential for gene expression and cellular function.
Emory researchers discovered that abnormal gene silencing, caused by overexpression of methyltransferase enzymes, can lead to breast cancer progression. The silencing of the TMS-1 gene, responsible for programmed cell death, may contribute to tumor growth and resistance to conventional therapies.
New research suggests that non-mutational gene defects, involving DNA methylation, contribute significantly to the development of cancer. Up to 10% of genes in some tumor types are found to be inactivated by aberrant DNA methylation, suggesting a much larger role for this process than previously thought.
A University of Iowa research team discovered that DNA methylation can contribute to oral cancer by silencing tumor suppressor genes. The study found that aberrant cytosine methylation patterns were present in oral cancer cells but not in normal human cells, suggesting a potential mechanism for cancer progression.
A new study reveals that genetic changes caused by atherosclerosis may be the reason why estrogen does not provide preventative effect against heart disease. Researchers found evidence of DNA methylation, which prevents the formation of estrogen receptors in cardiovascular tissue.
A new study by Whitehead researchers found that reduced DNA methylation may be responsible for decreased genomic stability and increased mutation rates in cancer cells. This could lead to a better understanding of the molecular origins of cancer.