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Science News for February 18, 2003


Radiologist training may affect accuracy of mammogram interpretation

A study found that recent radiologists interpreted screening mammograms more accurately than those with less training, while facilities with higher diagnostic volume showed improved accuracy. The researchers suggest additional studies to clarify the complex relationship between radiologist experience and mammogram interpretation.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateFeb 18, 2003

Cyclis Pharmaceuticals reports studies defining new mechanism for potential cancer therapies

Researchers at Cyclis Pharmaceuticals have discovered a new mechanism for treating cancer, involving the activation of the E2F1 protein with small molecule drugs. The findings, published in the Proceedings of the National Academy of Sciences, show that this approach can selectively kill cancer cells while sparing normal cells.

SourceFeinstein Kean Healthcare·JournalProceedings of the National Academy of Sciences·DateFeb 18, 2003

First draft of 'periodic table' of protein structures helps visualize nature's universe of proteins

Scientists have created a 3D map of the protein universe, organizing over 500 common motifs and revealing clusters that resemble cigars. This map helps visualize the relationships among all proteins in nature, shedding light on evolutionary changes and potential applications in biomedical research.

SourceUniversity of California - Berkeley·JournalProceedings of the National Academy of Sciences·DateFeb 18, 2003