Researchers at CABBI develop photoenzymatic system to efficiently synthesize chiral amines, crucial chemical building blocks with wide applications. The team's new method addresses a longstanding challenge in synthetic chemistry and offers a promising platform for biomanufacturing.
SourceUniversity of Illinois at Urbana-Champaign Institute for Sustainability, Energy, and Environment·JournalNature Catalysis·TypeExperimental study·DateJul 31, 2023
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers have identified a genetic cause for virgin birth in female flies, allowing them to reproduce without males. The ability is passed down through generations of females and can be induced in an animal that usually reproduces sexually.
SourceUniversity of Cambridge·JournalCurrent Biology·TypeExperimental study·DateJul 28, 2023
Researchers found a genetic link that explains how certain individuals store fat at the abdomen but remain protected from type 2 diabetes. This discovery could pave the way for personalized medicine, tailoring treatments to individual genetic variations.
SourceUniversity of Virginia Health System·JournaleLife·DateJul 27, 2023
Researchers found fungi can effectively degrade low-density polyethylene (LDPE) plastic without wood present. In the absence of wood, fungal biodeterioration of LDPE increased, suggesting a potential natural method for plastic waste management.
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Biotechnology holds promise for saving endangered tree species through a combination of traditional breeding approaches and innovative genetic engineering. The study emphasizes the need for public acceptance and regulators' support to harness biotech's potential.
SourcePurdue University·JournalNew Forests·TypeSystematic review·DateJul 6, 2023
A team of researchers has identified a unique genetic signature in CAR T-cells that enables them to persist in the body for a longer time, leading to improved remission rates for children with leukaemia. This discovery provides a new understanding of why some CAR T-cells last longer and can help improve treatment outcomes.
SourceUniversity College London·JournalNature Medicine·DateJul 5, 2023
Researchers developed a novel DNA marker-based system for identifying Japanese citrus cultivars, enabling quick detection of counterfeit fruit. The method can accurately identify cultivar-specific DNA polymorphisms within minutes, safeguarding Japan's unique citrus industry and its breeders.
SourceOkayama University·JournalBreeding Science·TypeExperimental study·DateJun 21, 2023
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A new study from the Stowers Institute for Medical Research reveals the placenta's polyploid cells play a vital role in supporting healthy embryonic development. The modified cell cycle controlling polyploidy is governed by the regulatory gene Myc, which supports DNA replication and prevents premature cellular aging.
SourceStowers Institute for Medical Research·JournalDevelopment·TypeExperimental study·DateJun 7, 2023
Researchers from the University of Surrey investigate how protons move in Hachimoji DNA, a synthetic form of DNA not yet found in nature. They find that proton transfer happens more easily in Hachimoji DNA compared to regular DNA, suggesting potential implications for mutation rates and genetic systems.
SourceUniversity of Surrey·JournalRSC Advances·DateJun 2, 2023
A team of scientists led by Professor Ivan Đikić and Christian Hübner identified the role of ubiquitin in regulating ER-phagy, a process involved in the degradation of the endoplasmic reticulum. This discovery sheds light on neurodegenerative diseases caused by defective FAM134B and ARL6IP1 proteins.
SourceGoethe University Frankfurt·JournalNature·TypeExperimental study·DateMay 26, 2023
Researchers used a multiomics approach to analyze changes in transposable elements after influenza A virus infection, identifying transcription factors contributing to individual responses. The study provides insights into the variable severity of illness among individuals infected with the same virus.
SourceKyoto University·JournalCell Genomics·TypeExperimental study·DateMay 22, 2023
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers have developed an automated calling algorithm for determining B and T cell clonality from NGS data with greater sensitivity than previous models. The new model increases the assay's sensitivity in detecting clonality, allowing for more accurate diagnosis and monitoring of lymphoproliferative disorders.
SourceImpact Journals LLC·JournalOncotarget·TypeData/statistical analysis·DateMay 16, 2023
Researchers discover that senescence-associated secretory phenotype (SASP) can induce neuroendocrine transdifferentiation (NED) in breast cancer epithelial cells, promoting tumor progression and aging-related features. SASP's dual role in cancer involves both antitumoral and tumorigenic effects.
SourceImpact Journals LLC·JournalAging-US·TypeCommentary/editorial·DateMay 12, 2023
Scientists have developed a method to increase the efficiency of CRISPR/Cas9 gene editing without viral material, stimulating homology-directed repair by threefold. This breakthrough improves nonviral gene editing and may lead to more efficient disease modeling and hypothesis testing.
SourceUniversity of California - Santa Barbara·JournalNature Biotechnology·DateMay 11, 2023
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers from the ALFA Score Consortium explore how nutrition and physical exercise can positively impact the aging process by modifying epigenetic changes. They find that healthy aging is associated with more tightly condensed chromatin, fewer histone post-translational modifications, and greater regulation by non-coding RNAs.
SourceImpact Journals LLC·JournalAging-US·TypeCommentary/editorial·DateMay 10, 2023
Researchers used AI tools to simplify a test for hepatitis C and SARS-CoV-2, achieving 97% accuracy for SARS-CoV-2 and 95% accuracy for the most prevalent version of hepatitis C. The team plans to refine the test, improve its ability to distinguish between strains, and potentially develop at-home tests in the future.
SourceUniversity of Florida·JournalCell Reports Medicine·DateMay 8, 2023
Scientists have developed a new method to deliver genetic information to stem cells using nanoparticles coated with a specific polymer, enabling more efficient control over cellular differentiation. This innovation has the potential to improve the efficiency and effectiveness of regenerative medicine treatments.
SourceXi'an Jiaotong-Liverpool University·JournalNano Letters·TypeExperimental study·DateMay 8, 2023
A new high-speed two-photon microscope was developed with an unprecedented line scanning frequency of 400 kHz, achieving up to 10,000 frames per second. This allowed for precise observations of complex biological processes in living tissues, including calcium signal propagation and blood flow measurements.
SourceSPIE--International Society for Optics and Photonics·JournalNeurophotonics·DateMay 3, 2023
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers have engineered a synthetic gene oscillator device that slows down the aging process in yeast cells by cycling deterioration between two detrimental states. This approach resulted in an 82% increase in lifespan compared to control cells, setting a new record for life extension through genetic and chemical interventions.
SourceUniversity of California - San Diego·JournalScience·TypeExperimental study·DateApr 27, 2023
A Mayo Clinic study found that people with severe obesity and a genetic pathway variant are at increased risk of developing hypertension. The research identified 168 carriers of the MC4R variant, who had a higher risk of hypertension compared to noncarriers.
SourceMayo Clinic·JournalMayo Clinic Proceedings·DateApr 18, 2023
The new CALANGO software helps untangle genetic factors associated with shared characteristics, such as antibacterial resistance and agricultural improvements. It enables scientists to explore vast amounts of genomic data across thousands of organisms.
SourceAston University·JournalPatterns·TypeData/statistical analysis·DateApr 14, 2023
A study led by Tokyo University of Science researchers identified Dectin-1's role in promoting colorectal cancer by enhancing PGE2 production and suppressing IL-22BP expression. The study used mouse models and clinical samples to validate the findings, which have immediate clinical implications for CRC patients.
SourceTokyo University of Science·JournalNature Communications·TypeExperimental study·DateApr 10, 2023
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
The funding will support preclinical research using genetically modified pigs, aiming to improve compatibility and reduce immune rejection in xenotransplantation. The goal is to enable human clinical trials and address the organ shortage crisis.
A study found that regular exercise increases mitochondrial fusion, benefiting muscle cells and maintaining physical fitness even in old age. Daily sessions of exercise throughout life delay the accumulation of dysfunctional mitochondria and decline in physical fitness.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalProceedings of the National Academy of Sciences·DateMar 29, 2023
Scientists from CSIC and UPV create modified ABA receptor activated by iSB09 molecule, increasing drought tolerance in plants. The combination efficiently activates the ABA pathway, triggering adaptive mechanisms and reducing water loss.
SourceUniversitat Politècnica de València·JournalScience Advances·TypeMeta-analysis·DateMar 28, 2023
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Chinese scientists have identified a key gene involved in crop alkaline tolerance, which may greatly improve crop yield in sodic environments. The study found that the gene negatively regulates alkaline stress by modulating the efflux of H2O2 under environmental stress.
SourceChinese Academy of Sciences Headquarters·JournalScience·TypeExperimental study·DateMar 23, 2023
Two novel genetically defined mouse models replicate two subtypes of human multiple myeloma, revealing the interaction of genetic aberrations as a key factor in development. The models will aid in identifying specific therapeutic strategies for individualized treatment.
SourceMax Delbrück Center for Molecular Medicine in the Helmholtz Association·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMar 16, 2023
Scientists create modified E. coli bacteria that cannot be infected by viruses while minimizing gene escape into the wild. This breakthrough technology has implications for reducing viral contamination in biotechnology production, such as insulin production and biofuel manufacturing.
SourceHarvard Medical School·JournalNature·TypeExperimental study·DateMar 15, 2023
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A study by Kumamoto University researchers reveals LSD1's role in regulating skeletal muscle response to environmental stress. The findings suggest that LSD1 moderates muscle adaptation to environmental conditions, with potential implications for maintaining muscle health and preventing diseases such as sarcopenia.
SourceKumamoto University·JournaleLife·TypeExperimental study·DateMar 7, 2023
Scientists have genetically modified potatoes and tomatoes to produce betacyanin, a pigment with anti-inflammatory properties. The transgenic vegetables demonstrated enhanced accumulation of the pigment, which showed improved effects in reducing inflammation in macrophage-like cells and murine models of colitis.
SourceTokyo University of Science·JournalBiotechnology and Bioengineering·TypeExperimental study·DateFeb 16, 2023
Researchers from Rice University have developed a new approach to control gene expression using proteolysis targeting chimeras (PROTACs). By reengineering the PROTAC molecular infrastructure, they demonstrated the ability to achieve chemically induced dimerization (CID), allowing for precise control over gene activation in specific loc...
SourceRice University·JournalJournal of the American Chemical Society·TypeExperimental study·DateFeb 14, 2023
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers found that cells don't pick certain sites to methylate, but rather where not to, due to the joints of messenger RNA. This discovery has implications for gene therapies, disease treatment, and our understanding of biology and evolution.
Researchers at Duke University have created a new approach to controlling cellular biochemical processes by building synthetic compartments that isolate biomolecules. This technique has the potential to be used to understand and fight disease, including the spread of antibiotic-resistant pathogens.
SourceDuke University·JournalNature Chemical Biology·TypeExperimental study·DateFeb 6, 2023
Researchers at NYU Langone Health and the University of Toronto have developed a new AI tool called ZFDesign, which enables customizable protein editing for treating genetic diseases. The tool promises to accelerate gene therapy development on a large scale, offering a potentially safer alternative to CRISPR.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature Biotechnology·TypeComputational simulation/modeling·DateJan 26, 2023
Researchers found that Sirtuin 7 regulates brown adipose tissue functions, leading to suppressed energy expenditure and thermogenesis. The study reveals a molecular pathway involving protein deacylation and mRNA binding, which will have implications for treating hypermetabolic conditions like cancer and obesity.
SourceKumamoto University·JournalNature Communications·TypeExperimental study·DateJan 19, 2023
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
New research from the University of Sheffield reveals genetically modifying rice to reduce stomata can make it more salt-resistant and survive in environments with high salt levels. This adaptation could help tackle food insecurity caused by climate change.
SourceUniversity of Sheffield·JournalNew Phytologist·TypeObservational study·DateJan 15, 2023
A multidisciplinary team of UC students developed a new understanding of spinal column formation and reengineered the process in mutant zebrafish. This breakthrough could lead to possible treatments for scoliosis in humans.
SourceUniversity of Cincinnati·JournalNature·TypeExperimental study·DateJan 11, 2023
Researchers genetically engineered yeast to produce vindoline and catharanthine, two pharmacologic precursors of the powerful anticancer drug vinblastine. The team successfully optimized biosynthetic pathways using advanced genetic engineering and synthetic biology-based approaches.
SourceBioDesign Research·JournalBioDesign Research·TypeExperimental study·DateJan 11, 2023
A WSU-led survey found that US consumers value grape taste more than gene editing, with appearance and pesticide concerns ranking second and third respectively. Most participants were indifferent to the use of CRISPR technology in table grapes.
SourceWashington State University·JournalPLOS ONE·DateJan 9, 2023
Smidt Heart Institute researchers have identified a way to control the natural 'fight back' response of heart cells against RNA therapies, leading to increased effectiveness. By targeting specific microRNAs, they were able to stabilize the heartbeat and boost gene expression.
SourceCedars-Sinai Medical Center·JournalCell Reports Medicine·DateDec 20, 2022
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A global registry for gene-drive modified organisms could facilitate transparent communication, monitor ecological impacts, and inform local decision-making. Experts agree that a registry is necessary for the fair development, testing, and use of gene-drive technologies.
SourceUniversity of California - San Diego·JournalNature Biotechnology·TypeCommentary/editorial·DateDec 15, 2022
Researchers highlight recent progress in organotypic models, which offer a balance between the accessibility and control of in vitro context. These models have been used to study various aging-related phenotypes, including skin, gut, and skeletal muscle, providing valuable insights into the underlying mechanisms.
SourceImpact Journals LLC·JournalAging-US·TypeLiterature review·DateDec 14, 2022
Researchers genetically engineered a microbial community that can convert CO2 into sugar and produce useful chemicals, effectively acting as a living carbon sink. The community, consisting of bacteria and cyanobacteria, produces chemicals with a negative carbon balance.
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateDec 9, 2022
G-Quadruplex DNA structures play a crucial role in regulating genes and cell processes, but their visualization is challenging due to the dynamic nature of double standard DNA. Fluorescence-active small molecule probes have emerged as a real-time visualization method, enabling researchers to detect G-quadruplexes with high selectivity.
SourceBentham Science Publishers·JournalCurrent Organic Chemistry·DateDec 8, 2022
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A recent study found that science misinformation about genetically modified crops reached a quarter of a billion people globally. The majority of articles containing GMO-related keywords contained false information, especially on human health concerns, which had the highest readership.
SourceBoyce Thompson Institute·JournalGM Crops & Food·TypeExperimental study·DateNov 17, 2022
Osaka University researchers have synthesized a fluorescent protein with the shortest emission wavelength to date, enabling the simultaneous tracking of multiple processes in cells. The new protein, Sumire, exhibits improved brightness and stability compared to existing fluorophores.
SourceOsaka University·JournalCommunications Biology·TypeNews article·DateNov 16, 2022
Scientists have created a way to track brain diseases like depression, Alzheimer's, and strokes using fluorescent mouse blood. The method allows for months-long study of blood flow in the brain, providing new insights into disease progression and development.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalCell Reports·TypeExperimental study·DateNov 14, 2022
Scientists at NTU Singapore have successfully modified a plant protein to increase vegetable oil yield. By improving the binding affinity of WRI1, the team was able to enhance oil accumulation in seeds by 15-18% under laboratory conditions.
SourceNanyang Technological University·JournalScience Advances·TypeExperimental study·DateNov 9, 2022
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
MU researchers, including Jay J. Thelen and Dong Xu, are exploring genetic modification to increase seed oil production in camelina and pennycress for biofuel use in the aviation industry. The team aims to create a sustainable 'green energy' source as an alternative to petroleum-based fossil fuels.
Researchers from North Carolina State University have developed a new method for identifying genes relevant to the aging process in the C. elegans roundworm model. By exposing thousands of worms to random genetic mutations, they can pinpoint which genes are associated with protein aggregation and reduced lifespan.
SourceNorth Carolina State University·JournaliScience·TypeExperimental study·DateNov 1, 2022
Researchers found a longer PR interval and prolonged QT duration in genetically modified pig hearts after transplantation into humans, indicating signs of electrical disease. The study provides a foundation for future research to better understand xenotransplantation's effects on the heart's electrical system.
Researchers at Leibniz-HKI discovered a yellow natural substance that regulates the multicellular stage of the amoeba <em>D. discoideum</em>. The polyketide, dictyoden, prevents premature hatching from spores, maintaining the development cycle. The study provides insights into the complex transition from single- to multicellularity.
SourceLeibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute -·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateOct 19, 2022
Engineered duckweed produces up to 10% oil content, a 100-fold increase over wild-type plants, with synergistic effects seen when combining gene modifications. The oil-rich plant can be easily harvested for biofuels or bioproducts, reducing competition with food crops and environmental waste.
SourceDOE/Brookhaven National Laboratory·JournalPlant Biotechnology Journal·TypeExperimental study·DateOct 11, 2022
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Scientists have identified long interspersed nuclear element-1 (L1) RNA as a promising new target for treating progeroid syndromes. Increased L1 RNA expression in cells from patients with these disorders led to deactivation of an enzyme, causing cell aging.
SourceKing Abdullah University of Science & Technology (KAUST)·JournalScience Translational Medicine·DateOct 4, 2022
A study published in The BMJ found that adopting a healthy lifestyle can reduce the risk of type 2 diabetes by up to 90% in women with a history of gestational diabetes. Women who adhered to five key lifestyle factors had a significantly lower risk of developing type 2 diabetes, regardless of their weight or genetic risk.
SourceBMJ Group·JournalThe BMJ·TypeObservational study·DateSep 21, 2022
Researchers engineered mosquitoes to produce compounds that stunt malaria parasite growth, reducing the risk of disease transmission. The technique could be combined with gene drive technology to drastically cut malaria transmission in real-world settings.
SourceImperial College London·JournalScience Advances·TypeExperimental study·DateSep 21, 2022
Researchers have genetically engineered human muscle cells to take up more sugar from the blood, reducing blood glucose levels by 20% in diabetic mice. The new tissue also shows promise for a single injection of tissue providing long-lasting glucose control.
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A new study published in The Crop Journal has identified the gl9 gene variant as a key factor in increasing grain size and reducing chalkiness in rice. By introducing this allele into elite rice varieties, scientists have improved grain length, width, and weight, leading to enhanced appearance quality and yield.
SourceCactus Communications·JournalThe Crop Journal·TypeExperimental study·DateSep 14, 2022
Researchers have genetically engineered yeast to produce vindoline and catharanthine, the precursors to vinblastine, a widely used anti-cancer drug. This breakthrough may lead to new sources of these compounds and reduce dependence on plant farming and logistics challenges.
SourceTechnical University of Denmark·JournalNature·TypeExperimental study·DateAug 31, 2022
A team of researchers from Ritsumeikan University in Japan has elucidated the mechanism behind the liquid-solid phase transition of FUS protein that leads to ALS. They discovered a new therapeutic target, arginine, which suppresses FUS aggregation and could delay ALS progression.
SourceRitsumeikan University·JournalPhysical Chemistry Chemical Physics·TypeExperimental study·DateAug 29, 2022
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.