Articles tagged with Genetic Engineering
Researchers successfully tested gene drive technology to control malaria-carrying mosquitoes in large cages mimicking natural environments. The technology, which spreads a genetic modification blocking female reproduction, worked as expected and showed significant population decline within one year.
Researchers have successfully genetically modified grass to detoxify residues of the military explosive RDX, contaminating groundwater and posing a threat to drinking water supplies. The genetically modified switchgrass plants removed 27 kg of RDX per hectare, offering a cost-effective and sustainable solution for environmental cleanup.
Researchers genetically modified mosquitoes to express antimalarial genes, which were then passed on to their offspring. The approach shows promise in reducing mosquito populations and combating malaria.
A new mouse model created by researchers at the University of Bonn reveals that GPI anchor deficiencies, a group of rare diseases, are caused by impaired transmission of stimuli at brain synapses. The mice exhibited cognitive deficits, altered social behavior, and increased susceptibility to epilepsy, mirroring human symptoms.
Scientists at UC Santa Barbara have developed a new approach to addressing the challenge of antibiotic-resistant bacteria by replacing antibiotics with fluoride. The method uses a genetically engineered cell that can survive in the lab but dies when exposed to fluoride, preventing its propagation into the natural environment.
A global research team led by the University of Göttingen explains how plant genetic engineering can combat micronutrient malnutrition. Biofortification using conventional breeding methods has already been successful in improving nutrition and health, but genetic engineering offers a way to further enhance benefits.
Scientists at KIT have successfully introduced genetic information into a multicellular cyanobacterium, Phormidium lacuna, using natural transformation. This breakthrough opens up possibilities for basic research and biotechnical applications, including the synthesis of biofuels like ethanol and hydrogen.
Bangladeshi farmers achieving higher yields and revenues through insect-resistant genetically engineered eggplant, providing a more sustainable crop option. The study found that Bt brinjal varieties earned growers 21.7% higher revenue, equivalent to around $664 per hectare.
A Japanese survey reveals differing perceptions of gene-edited crops among experts and the general public. Experts see benefits, while the public perceives risks despite acknowledging value. The findings shed light on the deficit model's boundaries in science communication.
The TU Dresden team presented their DipGene project, a DNA sequence-specific diagnostic method applicable in bacteria and human genomic DNA. The method is faster and cheaper than PCR, taking only five to ten minutes to detect predispositions to monogenic diseases.
Researchers have characterized three genes associated with insecticide resistance in malaria mosquitoes, found to cause resistance to all four classes of public health insecticides. This breakthrough work provides much-needed tools for monitoring the growing problem through molecular testing.
Scientists at EPFL have engineered aerolysin, a bacterium-produced toxin, to form narrow pores that can sense biomolecules with high resolution. This discovery opens new opportunities for sequencing biomolecules, such as DNA and proteins, and could lead to breakthroughs in gene sequencing and diagnostics.
A novel transfection method called nano-electro-injection delivers DNA into immune cells two to three times more efficiently than conventional methods. This technique improves the process of generating high-quality genetically modified immune cells for cancer immunotherapy, reducing cell stress and improving cell health.
Scientists have developed a new genetic tool called iSuRe-Cre that provides certainty in Cre-inducible genetic modifications. This innovation increases the efficiency and reliability of gene function analysis in mice, allowing for precise investigation of gene role during organ development, physiology, and disease.
A multi-institution research team, led by Worcester Polytechnic Institute's Eric Young, is developing a biosecurity tool to identify genetically engineered organisms in the environment. The tool uses unique DNA signatures to distinguish between engineered and naturally occurring microorganisms.
Scientists studied the impact of fragmentation on Dahl's toad headed turtle populations in Colombia, finding restricted gene flow and genetic erosion. They recommend gene flow restoration via genetic rescue to counteract these threats and provide guidance for this strategy.
The NIH supports an international moratorium on clinical germline editing due to safety, ethical, and philosophical concerns. The call comes after irresponsible research in China, where twins were born with altered DNA before implantation.
The proliferation of genetically modified seeds in India has led to 'choice overload,' where farmers struggle to make decisions due to a vast array of options. Farmers prioritize community expectations and social status over yield, driven by the desire to be successful and modern.
A study by the University of Exeter found that innuendo alone in news coverage can lead people to believe false information, spreading conspiracy theories. The research suggests that journalists should avoid including 'errant data' that may be misconstrued when there is uncertainty about facts.
A Pew Research Center survey finds that majority of Americans accept genetic engineering of animals to prevent disease transmission and grow organs for transplants. However, others oppose the use of technology to improve meat quality or revive extinct species, citing concerns about ecosystem risks.
A groundbreaking study by Oregon State University demonstrates the potential for genetically modified forest trees to prevent new seedlings from establishing. Researchers successfully engineered containment traits that limit the spread of genetically modified or exotic poplar trees, mitigating societal concerns over gene flow.
A recent study by Professor Jesper Lassen found no correlation between public reservations about genetically modified foods and parliamentary debate. Politicians focus on benefits and risks, ignoring the moral and ethical dimensions that concern citizens most.
Researchers have developed a new method for synthesizing insulin using self-assembly of polypeptide chains, achieving a 40% efficiency rate. This approach enables the production of customized insulin compounds without relying on genetic engineering, which could lead to the development of novel insulin preparations.
Scientists have developed a method to efficiently genetically modify T-cells from mice, allowing for targeted gene surgery and potential therapeutic applications. The technique involves using plasmids and CRISPR-Cas9 molecular scissors to introduce specific changes into the cells.
A new study shows that innuendo and pointing suspicion in news coverage can significantly increase belief in false facts. Researchers found that even implicit hints at conspiracy theories can lead to increased conspiracy beliefs, while debunking information can only partially reduce these levels.
Researchers discovered a chemical, HP-I, that regulates female mosquito sexual proclivities, helping females avoid multiple mates and reducing disease transmission. The protein's role in inter-species sex also holds promise for understanding complex reproductive patterns between different mosquito species.
A Japanese research team developed a refrigeration preservation technology that extends mouse sperm freezing period from three days to 10 days. This breakthrough enables safe and easy transportation of genetically modified mice worldwide, accelerating international collaborative research.
A new sensor molecule allows researchers to visualize calcium concentrations in living animals without genetic modification or radiation exposure. This breakthrough enables better understanding of disease processes and has potential applications in improving medical treatments.
A study by Rutgers University researchers suggests that gut bacteria at a young age contributes to the onset and progression of Multiple Sclerosis (MS). The study found that genetically engineered mice exposed to normal environment developed MS-like disease, highlighting the role of gut bacteria in triggering immune system changes.
Researchers at the University of Minnesota have developed a promising approach called synthetic incompatibility to prevent interbreeding between genetically engineered and unaltered organisms. This technology effectively makes engineered organisms a separate species unable to produce viable offspring.
A Penn State researcher has received a $1.9 million grant to develop a genetic lab tool using a mosquito virus to control malaria. The virus, called AgDNV, will be used to insert specific genes into mosquitoes, allowing scientists to study their phenotypes and develop malaria-control strategies.
Researchers at CNIC have developed new methods to induce multispectral genetic mosaics in vertebrate models, allowing precise study of gene behavior. The technology enables simultaneous analysis of multiple genes in different cell populations, providing insights into gene interaction networks and regulatory hierarchies.
Scientists use nonlinear reaction-diffusion equations to model gene movement and develop 'switches' that initiate and terminate gene drives, balancing genetic traits with embedded weaknesses. They also find that intense release in specific regions can trigger spreading, but can be stopped by barriers like pesticides.
Researchers have made a breakthrough in genetically engineering microalgae found in corals to enhance their stress tolerance and prevent coral bleaching. This could be a game-changer for ocean productivity and global coral reef conservation.
Scientists successfully completed the first EPA-approved outdoor field trial for genetically engineered algae, testing a strain in real-world conditions without adverse impact on native populations. The study demonstrates the feasibility of cultivating genetically engineered algae outdoors while maintaining engineered traits.
Researchers developed a gene therapy that restored balance and hearing in genetically modified mice with Usher Syndrome. The study's positive results suggest potential for treating various inherited vestibular and hearing disorders in humans.
Researchers at the University of British Columbia genetically engineered mice with higher levels of cadherin to resist cocaine addiction. The study found that extra cadherin prevents synapses from strengthening and forms pleasurable memories, thereby preventing addiction.
The release of genetically modified insects for pest control could lead to contamination in organic crops, harming farmers and eroding consumer confidence. International trade could be disrupted if detected contaminants are met with import bans.
Researchers genetically modified mosquitoes to resist infection from dengue virus, boosting their natural ability to fight the disease. The findings could be a prelude to developing a strategy to eliminate the threat of dengue.
A team of Vanderbilt scientists has developed a bioluminescent sensor that causes brain cells to glow in the dark, enabling researchers to track the interactions within large neural networks. The new technique uses calcium ions to detect neuron activity, offering a powerful tool for studying brain function.
Rice University scientists are building a tool to detect and quantify genetically modified organisms (GMOs) in the environment. The technology uses light transmission spectrometry to identify DNA or proteins from engineered crops and animals, which can have unintended consequences on ecosystems.
Researchers have developed genetically modified male flies that produce only males when mating, suppressing New World screwworm fly populations. The technique could increase the efficiency of sterile insect technique programs and provide a cost-effective solution for controlling livestock pests in tropical regions.
A new study suggests that increased sea temperatures can enhance and accelerate radiation-induced DNA effects in marine mussels. The research found that DNA damage appeared earlier at higher temperatures compared to lower temperatures, potentially compromising the mussels' ability to defend against genotoxic insult.
A new study shows that genetically modified pig hearts developed by US and LMU researchers can survive for more than 2½ years when transplanted into baboons. The findings demonstrate a promising breakthrough in xenotransplantation, with potential implications for human organ transplantation.
Kyoto University engineers have developed genetically modified E. coli that produce thebaine, a morphine precursor, 300 times more efficiently than yeast. This breakthrough could lead to the production of painkillers from microbes with low regulatory risk.
A new device may significantly speed up the process of inserting DNA into bacteria, which is a critical first step in genetic engineering. The device, developed by MIT engineers, uses a microfluidic system to identify optimal electric field conditions for reversible membrane poration.
Bioart uses genetic engineering, bacteria manipulation, and other scientific methods to create artistic works, sparking discussions about ethics and safety. The field has evolved from Fleming's 'germ paintings' to modern-day projects like genetically engineered silk worms and metagenomics analyses.
Researchers at the University of York have developed novel genetic engineering tools to manipulate genes required for antibiotic biosynthesis, enabling scientists to create new antibiotics. The technique has the potential to unlock the antibiotic potential of a significantly larger number of biosynthetic pathways than traditional methods.
Scientists at ETH Zurich have developed a genetically modified cassava variety that produces several-fold higher levels of vitamin B6, addressing the widespread deficiency in Africa. The new trait is stable under different conditions and has been confirmed to be bioavailable for human consumption.
A new policy analysis warns that current regulations are stifling the use of genetically engineered trees to combat catastrophic forest threats. The authors argue for a shift in regulatory approaches that focus on product rather than process, considering need, urgency, and genetic similarity.
Researchers argue that adding genes from wild cousins can strengthen crops without losing natural traits, benefiting organic farmers. Precise genetic engineering could make 'rewilded' crops compatible with organic agriculture values.
Researchers have genetically modified Salmonella to kill cancer cells and shrink tumors, offering a potential new therapy. The modified bacteria can target and destroy cancer cells while remaining safe for patients.
A new study finds that genetically modified soybean oil causes obesity, pre-diabetes, and fatty liver in mice fed a high-fat diet, but has fewer negative metabolic consequences than regular soybean oil. The results suggest that genetic modification may not always lead to healthier products.
Researchers developed a new genetic control mechanism using synthetic RNAs that can turn genes on and off. The breakthrough could lead to the creation of RNA-only genetic circuits with diagnostic capabilities.
Researchers have developed a set of genetic switches to control the function of genes in engineered organisms, preventing potential harm from theft or misuse. The switches use naturally occurring chemicals and can be customized for various products, including biofuels, food, and medicines.
Yale researchers developed a new bio-containment method using genetically modified bacteria that require a synthetic amino acid to activate genes. This approach solves a major obstacle to widespread GMO use, ensuring safer confinement of organisms in the environment.
A team of researchers at the University of Texas at Arlington has developed a genetic computer network model that can predict the onset of mental illnesses such as bipolar disorder and schizophrenia. The model uses single nucleotide polymorphism networks to analyze a patient's genetic pattern and apply personalized therapy.
Releasing genetically engineered male flies could be an effective way to control the Mediterranean fruit fly, a serious agricultural pest that causes extensive damage to crops. The method works by producing only male offspring, which then mate with local females and pass on a self-limiting trait, resulting in no viable female offspring.
The 2014 World Stem Cell Summit will bring together leading scientists, business leaders, and regulators to discuss the future of regenerative medicine. The summit will feature over 200 prominent speakers from more than 40 nations, exploring the latest scientific discoveries and innovative business models.
A study found that consumers were no more likely to support genetically modified crops for disease resistance when presented with stories of the Irish Potato Famine. Preconceived views about the risks and benefits of agricultural genetic engineering played a significant role in shaping consumer opinions. The research suggests that gene...