Reference Genomes

With cancer genome sequencing, be your own control

Researchers found thousands of genetic translocations in both healthy and cancerous mouse cells, highlighting the importance of considering individual genetic backgrounds. By using 'de novo assembly', scientists can compare a patient's cancer cells to their own healthy cells, reducing errors in translocation discovery.

University of Louisville leads new study to map disease genes in horses

Researchers are developing a new reference genome sequence for domestic horses to better understand genetics in animal health and well-being. The new sequence aims to improve the ability to identify diseases and traits in horses.

New genomics study shows ancestry could help solve disease riddles

A recent genomics study reveals that comparing diseased patients' genomes with those of people from similar ancestries can dramatically simplify searches for harmful mutations, potentially leading to more effective treatments. The study's tool, the Scripps Genome Adviser, uses a reference panel of less than 20 genomes to identify ances...

Researchers look to relatives for clues in quest to develop sources of bioenergy

Using the foxtail millet genome as a reference, researchers have developed genetic tools for switchgrass, a promising biofuels feedstock. The high-quality genome allows for efficient transformation methods and understanding of adaptation mechanisms, making it an ideal model system for studying grasses.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Ethnicity-specific reference genomes improve genetic risk assessment using whole-genome sequencing

A study introduces ethnicity-specific reference genome sequences to analyze whole-genome sequencing data, improving disease risk assessment. The approach was demonstrated in a four-person family and showed increased accuracy in detecting rare variants and reducing errors.

BCM scientists sequence microbes as part of the Jumpstart for Human Microbiome Project

The Baylor College of Medicine team has successfully sequenced 178 microbial reference genomes representative of the human body. These reference genomes will help scientists understand and contextualize the data accumulated over time, providing valuable insights into the complex relationship between humans and their microbiota.

New methods identify thousands of new DNA sequences missing from the human genome reference map

Researchers have discovered 2,363 new DNA sequences corresponding to 730 regions on the human genome, representing segments not charted in the reference map. The findings suggest that new genome assemblies based solely on next-generation sequencing might miss many of these sites.