Articles tagged with Type 2 Diabetes
A recent study found that night work can significantly impair glucose tolerance, increasing the risk of Type 2 diabetes among shift workers. The research showed peak glucose levels were 16% higher during night shifts compared to day shifts.
A new study finds that soccer training significantly improves the flexibility of the heart, reducing blood pressure and increasing exercise capacity in patients with type 2 diabetes. The study also shows reduced need for medication and improved physical condition.
Leading diabetes expert argues that 'Type 2 diabetes' is a category error, implying an entity that doesn't exist. This mislabeling has led to sub-optimal treatment for patients. Professor Edwin Gale proposes replacing the term with 'idiopathic hyperglycaemia', emphasizing individualized treatments based on varied causes.
Children who develop Type 2 diabetes are at high risk for early complications, including heart and kidney problems. The study found that young patients were more likely to develop hypertension and fatty liver due to obesity.
A meta-analysis of randomized clinical trials found that fish oil supplementation modestly increases adiponectin levels in the bloodstream. This hormone is associated with lower risk of diabetes and heart disease. The study suggests potential benefits of fish oil consumption on glucose control and fat cell metabolism.
Researchers at the University of North Carolina will assess three types of blood sugar home testing approaches on patient outcomes in a community-based clinic setting. The study aims to inform better, evidence-based decisions about glucose monitoring for patients with type 2 diabetes not treated with insulin.
Harvard researchers have discovered a novel hormone that regulates glucose production in the liver, offering new avenues for treating type 2 diabetes. The study found that switching off this hormone improves glucose metabolism, providing a potential therapeutic target.
Researchers created a new mouse model to study the development of type 2 diabetes, using middle-aged mice fed fatty food until old age. The study confirmed that inflammation in pancreatic islets leads to the disease, while DPP-4 inhibitors maintain good insulin production and prevent inflammation.
A recent study at Lund University has discovered a key factor behind gastric bypass surgery's ability to rapidly send type 2 diabetes into remission. The researchers found that insulin levels and intestinal hormones increase significantly after the procedure, suggesting a new potential treatment avenue for diabetes patients.
Researchers found that gastric bypass surgery increases insulin and GLP-1 levels after meals, helping patients manage type 2 diabetes. The study used catheters to mimic pre-operative digestion and compared hormonal activity post-surgery.
Green tea extract was shown to reduce body weight gain and insulin resistance in mice, especially when combined with polyethylene glycol. This compound prolonged gallated catechin absorption, limiting glucose uptake and improving glucose tolerance.
Researchers at Harvard University have discovered a hormone called betatrophin that increases insulin-secreting pancreatic beta cells by up to 30 times the normal rate. This could lead to a more natural regulation of insulin and reduced complications associated with diabetes.
A new study published in Diabetologia suggests that consuming one 12oz serving of sugar-sweetened soft drinks daily can increase the risk of developing type 2 diabetes by 22% in European populations. The research found a statistically significant association between artificially sweetened soft drink consumption and an increased risk of...
Researchers at Johns Hopkins Children's Center found that a previously minor protein called EPAC2 plays a central role in regulating insulin production. The study suggests that targeting EPAC2 with drugs could potentially restore pancreatic cell function and reverse Type 2 diabetes.
A study published in the BMJ found that a 5kg population-wide weight loss resulted in a significant reduction in Type 2 diabetes and cardiovascular disease mortality. The Cuban experience of rapid weight loss during economic crisis demonstrates the potential health benefits of reversing the global obesity epidemic.
A Danish study found that patients who tailor their own treatment in cooperation with their doctor can reduce their risk of complications, including heart attacks, with up to 20%. The study also shows that taking individual needs into consideration is crucial when treating patients with multiple diseases.
A new study found that higher levels of mercury exposure in young adults increase their risk for type 2 diabetes later in life. The study, led by Indiana University School of Public Health-Bloomington epidemiologist Ka He, established the link between mercury and diabetes in humans.
Researchers found an independent association between decreased melatonin secretion and increased risk for the development of type 2 diabetes. Lower nocturnal melatonin secretion was associated with increased insulin resistance in women, doubling their estimated diabetes incidence rate compared to those with higher melatonin secretion.
A new study from Brigham and Women's Hospital found that low nocturnal melatonin secretion levels are associated with an increased risk of developing type 2 diabetes. The study, which accounted for other established risk factors, suggests that melatonin plays a role in regulating glucose metabolism and risk of diabetes.
Researchers found that a restrictive diet following bariatric surgery leads to rapid improvements in blood glucose levels. The study's findings suggest that controlling food intake is key to successful diabetes remission.
A new study by Lund University researchers has found that epigenetic changes, such as DNA methylation, can influence the function of insulin-producing cells and alter genetic risk variants for type 2 diabetes. The findings suggest that these modifications may play a key role in the development of the disease.
A study from Boston University School of Medicine reveals that B cells secrete pro-inflammatory cytokines promoting insulin resistance and directly regulating inflammatory T cells. This discovery supports the exploration of FDA-approved B cell depletion drugs as novel agents to prevent obesity-associated inflammation and type 2 diabetes.
Researchers found that ranolazine, an anti-anginal drug, significantly reduced weekly episodes of chest pain in patients with type 2 diabetes. The study also showed that the drug had a more pronounced effect on reducing angina frequency in patients with poorer glucose control.
A recent study found that women with gestational diabetes are at risk for developing Type 2 diabetes, with a significant defect in insulin secretion identified as a key factor. The study's findings indicate that up to half of Asian women who had gestational diabetes may develop Type 2 diabetes within eight years of giving birth.
New research suggests that reducing sedentary time by 90 minutes per day can lead to significant health benefits for individuals at high risk of developing type 2 diabetes. The study found that sedentary time was more strongly associated with cardiometabolic markers than total physical activity or vigorous exercise.
A two-year study found that gastric bypass surgery reverses diabetes by uniquely restoring pancreatic function, particularly in reducing belly fat. The study showed a remarkable 5.8-fold increase in overall pancreatic cell function in patients who underwent gastric bypass.
A randomized controlled trial found that community health workers led by a nurse case-manager improved blood sugar levels among Samoans with type 2 diabetes. The intervention, which included culturally tailored education and home visits, resulted in clinically significant improvements in HbA1c levels.
A USC study finds that progestin-releasing long-acting reversible contraception (LARC) devices may pose a slight negative impact on metabolic markers, raising the risk for type 2 diabetes in healthy, obese reproductive-age women. The research concludes that LARC appears safe but merits further investigation.
A large population-based cohort study of 7,500 men in Sweden found that permanent stress increases the risk of type 2 diabetes. The study showed that men who reported permanent stress had a significantly higher risk of developing diabetes compared to those with no or periodic stress.
A study published in Environmental Research found a direct relationship between pesticide exposure and type 2 diabetes prevalence. Pesticide concentrations were significantly higher in the adipose tissue of people with type 2 diabetes, suggesting that pesticides may be an underlying factor in its development.
Researchers at University of Bristol identify MC4R as critical regulator of brain's response to obesity, also linked to increased blood pressure and type 2 diabetes. The study reveals a mechanism by which MC4R balances sympathetic and parasympathetic nervous system activity.
A new study published in Science Translational Medicine has found a strong link between binge drinking and the development of insulin resistance, which can lead to Type 2 diabetes. The research suggests that alcohol disrupts insulin-receptor signaling, causing inflammation in the brain and increasing the risk of metabolic disorders.
Researchers discovered a paradoxical relationship between diminished mitochondrial function and increased insulin sensitivity in mice. The study found that mice with mitochondrial mutations lived longer and had reduced body fat due to increased fat utilization.
A study found that among individuals with diabetes, those with both diabetes and kidney disease have a mortality rate of 31.1%, compared to 11.5% for those with diabetes but without kidney disease. Preventing and treating kidney disease in diabetics may be crucial to reducing mortality risk.
Research at the University of Missouri found that certain exercises benefit obese men but not women with Type 2 diabetes. Obese women may require longer or higher-intensity exercise programs to see similar improvements in cardiovascular function.
A Wayne State University researcher is evaluating the effectiveness of a 14-week text message-based behavioral intervention targeting Type 2 diabetes and its risks. The program, txt4Health, delivers tailored messages to users based on their individual risk for developing Type 2 diabetes.
A team of UCSB researchers has identified changes in cellular metabolism as the triggering factor for Type 2 diabetes. By studying the four types of components that make up cells, they found a 'tipping point' where metabolic threshold is crossed, leading to beta cell failure and insulin regulation issues.
Researchers found metformin improves body mass index (BMI) and fasting glucose levels in obese children at risk for type 2 diabetes. The study's results suggest a potential treatment option for preventing the onset of type 2 diabetes in childhood, offering hope for reducing long-term health risks.
Recent studies suggest that moderate coffee consumption may reduce the risk of developing type 2 diabetes. Epidemiological evidence shows a 25% lower risk associated with three to four cups of coffee per day.
Researchers identified four new genetic regions associated with birth weight, which also link to adult metabolism and disease. The study found that these genetic regions influence blood pressure, height, and type 2 diabetes risk in adulthood.
A new study by USC and University of Oxford researchers indicates that large amounts of high fructose corn syrup (HFCS) in food supplies worldwide may contribute to the rising global epidemic of type 2 diabetes. Countries using HFCS had a 20% higher prevalence of diabetes than those not using it.
Research found that people with diabetes who have adequate vitamin D are less likely to develop clogged arteries. In contrast, insufficient vitamin D leads to immune cells binding to blood vessels and trapping cholesterol.
A study found that patients newly diagnosed with type 2 diabetes often receive little information on diet and physical activity, leading to feelings of isolation. The research highlights the need for easily accessible resources and support to help patients manage their condition.
A pilot program at the University of Ottawa Heart Institute has demonstrated a significant improvement in patient care for diabetic patients. The program resulted in higher notifications to doctors, referrals to community diabetes management programs, and lower average blood sugar levels among in-patients.
A large-scale international study has identified three new gene variants associated with body mass index (BMI) levels in adults, providing fundamental insights into the biology of adult obesity. The study used a versatile gene discovery chip to detect gene variants involved in lipid-related diseases and other disorders.
Old Order Amish children are twice as physically active and three times less likely to be overweight than non-Amish peers. This high level of activity is inversely correlated with their body mass index, suggesting a protective effect against developing Type 2 diabetes.
A study suggests that Type 2 diabetes increases the risk of Barrett's Esophagus (BE) in diabetic men, with a twofold increase compared to non-diabetic men. The risk is higher in men due to differences in fat distribution, which may contribute to the association between Type 2 diabetes and BE.
The new guidelines suggest using a risk calculator to determine the risk level for general population, and recommend no routine screening with blood tests for adults at low or moderate risk of diabetes. For high-risk adults, screening is recommended every 3-5 years using A1C blood test.
Regular exercise can improve fitness levels in people with type 2 diabetes by up to 40% after 12-20 weeks of training. This reduces the impact of the disease on cardiovascular health and decreases mortality risk.
A study has found that nearly half a million people in three East London boroughs are at high risk of developing type 2 diabetes within the next decade. The 'East London Diabetes Belt' maps areas of high risk, highlighting need for targeted public health strategies.
Researchers identified 14 novel biomarkers for type 2 diabetes that can serve as the basis for developing new treatment and prevention methods. These biomarkers provide insight into the complex mechanisms of this disease, which are still not fully understood.
A study published in Annals of Behavioral Medicine found that gender-specific group therapy reduced depressive symptoms in women with Type 2 diabetes by half compared to usual care. The therapy program, SWEEP, taught participants how blood sugar affects emotions and helped them recognize stress signs.
A new study published in The Lancet found that widespread diabetes screening programs do not reduce overall mortality rates. The study, which included over 20,000 patients, also showed no significant difference in mortality rates between screened and non-screened groups.
A 5-year, $134 million grant from the National Institute of Health will support a clinical trial examining four glucose-lowering medications for type 2 diabetes treatment. The study aims to determine which therapy most effectively and safely reaches and maintains near normal levels of blood glucose.
A study published in Nature reveals that people with type 2 diabetes have a high level of pathogens in their intestines, which can increase resistance to certain medicines. The research also identifies biological indicators that could be used for faster and earlier diagnosis of the disease.
A new study published in the Journal of the American Medical Association found that obese individuals with visceral fat are at a higher risk for developing Type 2 diabetes. In contrast, those with excess abdominal subcutaneous fat were not at greater risk. The study, which sampled over 700 obese adults, used imaging methods to determin...
Researchers at Sahlgrenska Academy, University of Gothenburg, have found that metformin is effective in reducing the risk of cardiovascular disease, serious infection, and death in patients with mild kidney impairment. The study suggests that metformin can be prescribed for many more patients with diabetes than previously thought.
Researchers at Columbia University Irving Medical Center discovered that beta cells in type 2 diabetes do not die but de-differentiate under stress, suggesting a potential new approach to treatment. By targeting signaling pathways such as Wnt or Notch, scientists may be able to promote re-differentiation of beta cells.
A study published in the New England Journal of Medicine reveals that mutations in the PTEN gene can improve metabolism and increase insulin sensitivity in people with Cowden syndrome. The researchers found that those with Cowden syndrome had higher levels of obesity, but the extra weight was caused by extra fat storage, not muscle mass.
A recent study published in Diabetes Care found that Latinos are more vulnerable to fatty pancreas and Type 2 diabetes due to their ability to store excess fat in the pancreas. This can lead to a reduced capacity for insulin production, increasing the risk of developing the disease.