Articles tagged with Gut Microbiota
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A recent study published in Cell reveals a new mechanism in the gut microbiome that regulates pro- and anti-inflammatory cells, potentially preventing inflammatory bowel disease. The research also suggests that changes in the gut microbiome can increase the risk of other autoimmune disorders.
Research suggests that mouth bacteria can contribute to conditions like IBD, UC, and Crohn's disease by triggering severe inflammation in susceptible individuals. The study found that saliva samples from patients with these diseases contain Klebsiella bacteria, which can colonize the intestine and exacerbate symptoms.
A BYU study with mice reveals stress can alter gut microbiota to resemble a high-fat diet, potentially contributing to gender-specific health disparities. Researchers found distinct changes in female mice's digestive microorganisms upon exposure to stress.
A new study suggests that high-fat diets can change gut fungi and potentially contribute to the development of obesity. The research shows significant differences in fungal and bacterial communities between mice fed standard and high-fat diets.
Researchers aim to reduce comorbid illness in people living with HIV by developing personalized prebiotic and probiotic therapies, targeting gut bacteria balance. The study seeks to attenuate metabolic health issues associated with harmful alcohol use and heart disease.
Researchers found that formula-fed or cesarean-delivered infants had altered bacterial colonization trajectories compared to vaginally-born and breastfed babies. This could have implications for their future health, particularly in the development of food allergies.
New research finds that antibiotic use reduces the diversity of microbes in the gut, making it harder for the immune system to fight off infections. This disruption can compromise the intestinal barrier and leave the gut vulnerable to severe infection.
UC Davis Health researchers found that dietary fiber acts as the right fuel to help intestinal cells maintain gut health. The beneficial microbes metabolize indigestible fiber to produce short-chain fatty acids, signaling cells to maximize oxygen consumption and limit harmful microbes.
Scientists found that certain compounds produced by gut bacteria can predict how animals will respond to high-fat diets, including weight gain and tolerance to glucose. The study uses urine chemical signatures to identify individuals at risk of obesity and related health conditions.
Researchers found that restoring a healthy balance in gut bacteria can treat Autism Spectrum Disorder (ASD) symptoms. The review highlights several studies showing positive impacts of probiotics, prebiotics, diet changes and faecal matter transplants on ASD symptoms.
Researchers found that capsaicin in red chili prevents microbial dysbiosis and gut barrier dysfunction, leading to reduced inflammation and obesity. The study suggests that the gut microbiome plays a critical role in the anti-obesity effects of capsaicin.
Researchers discovered that changing the circadian clock in mouse liver alters how the body responds to diet and changes the microbes living in the digestive tract. The study found that mice lacking a specific gene in their liver had different gut microbiomes and responded differently to weight loss diets.
Scientists identify abnormal levels of specific gut bacteria in individuals with chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS), including those with and without irritable bowel syndrome (IBS). The study suggests that analyzing fecal microbiome may help subtype patients with ME/CFS.
Renowned researchers gathered to discuss stevia's health benefits, safety, and innovations in low/zero calorie sweeteners. Stevia was found to not alter during extraction and purification, providing evidence for its naturality, while research on its impact on blood glucose, diabetes, and overall health showed promising results.
A new study reveals that newborns are more prone to intestinal infections due to underdeveloped gut microbiomes. Colonization with healthy adult microbes significantly reduces disease in infected infant mice, highlighting a potential way to boost their immune system.
A new study finds that deep transcranial magnetic stimulation (dTMS) causes weight loss in obese individuals by improving their intestinal bacteria composition. After five weeks of treatment, dTMS-treated subjects lost more than 3 percent of their body weight and 4 percent of their fat compared to the control group.
Researchers from U-M Medical School and VA Ann Arbor Healthcare System studied the DNA of bacteria in healthy volunteers' lungs, finding most bacteria arrived through microaspiration. The study confirms that bronchoscope-based techniques can be used to study the lung microbiome in both healthy and sick individuals.
Preliminary study in mice suggests that aged gut bacteria can worsen brain damage after a stroke. Researchers found that mice treated with older gut bacteria had impaired recovery and higher levels of immune cells that worsen stroke severity.
Researchers found that the Inuit gut microbiome is remarkably similar to that of urbanized Westerners, with subtle differences in relative abundances of individual taxa. Dietary fiber is identified as a major factor driving the overall composition of the microbiome.
Researchers at the University Health Network found that a single fecal transplant is not more effective than the standard of care in treating recurrent C. difficile infection. The study's results suggest that more research is needed to determine the effectiveness and long-term implications of fecal transplantation.
Researchers discovered that replacing missing gut bacteria or restoring a key metabolite called inosine could help treat children with IPEX syndrome, an often fatal autoimmune disease. The study found that probiotic Lactobacillus reuteri and A2A receptor agonists inhibited T cell-mediated autoimmunity, extending the animals' life span.
A recent study published in Molecular Metabolism has found that cholesterol from animal sources helps mice burn fat, while plant-based fats hinder it. The research suggests a critical link between gut bacteria and energy metabolism, challenging the conventional wisdom on dietary fats and obesity.
New research identifies nitrogen as a key driver for gut health, revealing how diet impacts the microbiota. The study suggests that the availability of intestinal nitrogen to microbes is crucial in shaping the microbiome.
A new study has identified a connection between gut microbiota and fat distribution in children and teenagers, with obese youth having different microorganisms living in their digestive tracts. The research suggests that short-chain fatty acids produced by certain gut bacteria can contribute to the development of obesity.
A study published in Frontiers in Microbiology found that pesticides applied to hives to control Varroa mites can damage the gut microbiome of honeybees, impacting their ability to metabolize sugars and peptides. The research suggests that these chemicals can specifically harm the microbes crucial for honey bee nutrition and health.
HIV-infected mothers' breast milk alters oligosaccharide composition, leading to less diverse and immature gut microbiomes in their uninfected infants. This study suggests preventing microbiome disruptions may improve HIV-exposed babies' health.
Researchers found that chronic high fat diet disturbs neural messages in rats by shifting gut bacteria populations. Manipulating the gut microbiome can reverse this effect, leading to less overeating and weight gain. Additionally, specific foods like blueberries may also target and improve the microbiota composition.
A study of 39 Finnish infants found that antibiotic treatments during childhood reduced the diversity and stability of their intestinal microbiota. The research highlights the potential long-term health consequences of unnecessary antibiotic use in children.
New studies show antibiotics can delay infant microbiome development, reduce bacterial diversity, and lead to temporary antibiotic resistance gene presence. The findings suggest a need for further research on long-term consequences of gut microbiome disturbances linked to obesity, diabetes, and allergies.
Researchers have discovered a signature of gut bacteria associated with primary sclerosing cholangitis (PSC), a liver disease with no effective treatment. The findings may lead to a novel diagnosis tool and microbiota-based therapies, enabling better identification of PSC patients and personalized treatment approaches.
A recent study found that broad-spectrum antibiotics can raise the risk of complications from stem cell transplantation, including graft-versus-host disease. The study suggests that selecting antibiotics that spare
A recent study reveals differences in gut bacteria between children with and without multiple sclerosis. Key findings include an association between MS and increased inflammatory bacteria, as well as decreased anti-inflammatory bacteria. The discovery may pave the way for new therapeutic approaches by identifying novel drug targets.
A systematic review of seven randomized controlled trials found little evidence of an effect of probiotics on the gut microbiota of healthy adults. The study suggested that measuring the effect of probiotics in healthy individuals is more difficult due to the lack of a clear definition of a normal or healthy fecal microbial community.
Parasitic worms, or helminths, have been found to beneficially influence the composition of gut microbiota in individuals with inflammatory bowel disease. By infecting mice deficient in a gene that models Crohn's disease, researchers discovered that these parasites restore a compromised layer of mucus and intestinal cell morphology.
Early antibiotic use can permanently alter the diversity of children's immune cells, potentially leading to increased risks of inflammatory bowel disease and allergies. The study aims to understand how antibiotics impact T cell education and balance in the gut microbiota.
A new animal study finds that exposure to triclocarban, a common ingredient in antibacterial soap, can alter the composition of intestinal bacteria and other micro-organisms in offspring. The study suggests that this disruption may have unintended health consequences, including changes in obesity, diabetes, and asthma.
A new study in mice suggests that a mother's microbiome shapes her offspring's immune system. The research found that maternal antibodies facilitate the transmission and retention of microbial molecules from a mother to her offspring.
Despite increased demand, medical professionals are unable to recommend vaginal seeding due to the lack of evidence. Research suggests a potential risk of transferring harmful bacteria to the baby via swabbing, and there is currently only one ongoing study into its effects.
A new study reveals that the transition to family foods drives gut microbiota development in infants, rather than maternal obesity. The study found that breastfeeding duration and complementary diet composition played key roles in shaping the infant's gut microbiome.
A recent study found that a mother's diet during pregnancy and lactation significantly affects the composition of her breast milk microbiome. The researchers speculate that this may contribute to the establishment of the infant's gut microbiome, potentially influencing their disease susceptibility. The study provides new insights into ...
The study found that antibiotic use in early childhood alters the composition of intestinal microbiota, reducing biodiversity and affecting age-driven development. Macrolide antibiotics were particularly associated with changes in microbiota features linked to obesity and metabolic diseases.
A study published in Molecular Nutrition and Food Research found that rats who cycled between healthy and junk food diets over 16 weeks showed similar gut microbiota changes to those fed junk food continuously. The researchers suggest targeting certain gut bacteria may help treat metabolic disorders.
A Georgia State University researcher is investigating how the adaptive immune system can control intestinal bacteria to prevent inflammation in the gut. The project aims to identify a way to activate the mucosal immune system to reduce levels of bacteria with high potential to promote inflammation.
Researchers at Université de Genève found that cold exposure alters microbiota composition, leading to increased brown fat activation, improved insulin sensitivity, and weight loss. The discovery highlights the key role of Akkermansia muciniphila in regulating nutrient absorption and may lead to new anti-obesity treatments.
Two studies found that a specific gut bacteria, Bifidobacterium, is positively associated with anti-tumor T cell responses and upregulates genes critical for anti-tumor responses. Fecal transplants also slowed tumor growth in mice treated with immunotherapy agents.
Experts share insights on fecal microbiota transplantation, Clostridium difficile infection, and constipation management. Key findings highlight predictors of treatment failure and the cost-effectiveness of competing strategies for managing multiply recurrent C. difficile infections.
A study by researchers at the University of Pennsylvania School of Medicine found that different treatments for Crohn's disease in children have distinct effects on their gut microbiome. The use of antibiotics suppressed bacterial growth but facilitated fungal growth, while immunosuppressant medications reduced inflammation and bacteri...
A Georgia State University researcher is investigating the impact of emulsifiers on gut microbiota, leading to chronic inflammatory diseases and metabolic syndrome. The study aims to determine how emulsifiers alter the intestinal tract's relationship with beneficial bacteria.
Scientists have discovered that the gut microbiome of right whales and other baleen species shares traits with both cows and meat-eating predators. This dual microbial community enables whales to digest not only copepods but also their chitin-rich shells, providing a significant nutritional benefit.
A new study found that daily changes in mouse gut bacteria are linked to the internal clock and gender. The researchers analyzed circadian rhythms in abundance and type of microbiota in mice and found that female mice showed more significant oscillation than males.
A study found that severe burns alter bacteria populations dramatically, leading to a decrease in beneficial bacteria and an increase in potentially harmful Enterobacteriaceae. This imbalance may contribute to sepsis and other infectious complications in burn patients.
A study by University of Pennsylvania researchers found that maternal stress during pregnancy can 'reprogram' the developing brains of her children through changes in the vaginal microbiome. This initial exposure affects gut microbiota, metabolism, and brain development.
Research suggests that maternal stress during pregnancy can impact offspring gut and brain development by altering the vaginal microbiome. This study found disruptions in both maternal and offspring gut microbiota composition, leading to metabolic reprogramming of the gut and brain.
Giant pandas have a carnivore-like gut microbiota that can't efficiently digest bamboo due to the lack of genes for plant-digesting enzymes in their genome. Their gut diversity is also lower compared to other herbivores, leading to nutritional challenges and increased risk of extinction.
Recent studies show that breast milk contains beneficial bacteria to protect infants from diseases, while probiotics may restore balance in the gut and improve psychiatric symptoms in autism. Research also highlights the connection between gut microbiota and cancer prevention and treatment, as well as diet and intestinal health.
Research suggests that African American men with pre-diabetic blood sugar levels have fewer beneficial and more harmful intestinal bacteria. The study found that a specific microbiota is associated with stable, normal blood glucose levels, while a different profile is linked to pre-diabetes.
A study by North Carolina State University, Indiana University and Wellesley College found that the gut microbiome of honey bee queens remains consistent regardless of environment. The researchers characterized the microbiome throughout the queen's development, from larval stage to emergence as adults.
Researchers found that gut microbiota affects mucus barrier properties in mice, with different microbial compositions leading to varying levels of protection against bacterial invasion. The study suggests that a well-developed inner mucus layer is crucial for overall health and highlights the importance of the gut microbiota composition.
A new study links molecular signaling pathways in the gut, intestinal microbiome, and development of nonalcoholic fatty liver disease (NAFLD). Disruption of the gut microflora prevented NAFLD in mice fed a high-fat diet, suggesting that altering microbial populations may protect against the disease.
Researchers found a link between gut microbiota and Parkinson's disease, with patients having lower levels of Prevotellaceae bacteria and higher levels of Enterobacteriaceae family in their intestines. The study suggests that intestinal dysfunction may be part of the pathology and potentially related to the progression of the disease.