Articles tagged with Gut Microbiota
Eating a Mediterranean diet for a year boosts beneficial gut bacteria, reduces inflammation, and may help curb frailty and cognitive decline in older people. The diet is associated with increased diversity of the microbiome, improved brain function, and reduced harmful inflammatory chemicals.
A study by Dr. Raylene Reimer found that low-calorie sweeteners increased body fat and disrupted gut microbiota in offspring, even when consumed during pregnancy or breastfeeding. The findings suggest a potential link between artificial sweeteners and obesity risk in early life.
A specific gut bacterium, segmented filamentous bacteria (SFB), was found to impair normal skeletal growth and maturation in post-pubertal mice. This is achieved through a Gut-Liver-Bone Axis, where SFB elevates immune responses leading to increased osteoclast activity and decreased osteoblast activity.
A study by Johns Hopkins Bloomberg School of Public Health found that people on high fiber diets are 40% more likely to experience bloating if they consume protein-rich diets. The researchers suggest that substituting high-quality carb calories for protein calories may reduce bloating and make these diets more tolerable.
Research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that teens with obesity and PCOS have an altered gut microbiome compared to those without the condition. This altered microbiome is associated with higher testosterone levels, metabolic complications, and other health risks.
A special issue of Harvard Review of Psychiatry explores new treatments for major depressive disorder (MDD) by examining five key areas, including gender differences, neuroscience-based interventions, the role of the microbiome, opioid-based therapies, and technology in treatment. The research aims to develop more effective treatments ...
A new study finds that a high-fat, high-sugar diet alters the intestinal endocannabinoid system and changes the gut microbiome, with potential interactions between specific bacterial genera and eCB activity observed. These findings could help develop better nutritional strategies to prevent or treat metabolic complications.
Researchers found that Lactobacillus rhamnosus can restore a balanced intestinal microbiome and counter liver damage caused by chronic alcohol consumption. The probiotic effect of the bacteria reduced inflammation and fat accumulation in the liver, indicating potential therapeutic applications for alcohol-induced liver disease.
A recent study by the University of Helsinki found a significant link between increased use of antibiotics and an elevated risk of developing Parkinson's disease. The study suggests that excessive antibiotic use can disrupt the gut microbial ecosystem, leading to pathological changes in the intestine years before typical symptoms appear.
A study found that premature infants with abnormal gut microbiomes are more likely to experience stunted growth. Researchers tested stool samples weekly and discovered a significant association between dysbiosis and growth faltering, even after follow-up visits at ages 2 and 4.
Researchers studied African megafauna diet and gut microbiome, finding correlations between diet composition and microbiome composition. Seasonal changes in diet and microbiome were observed, with some species exhibiting little variability and others showing significant differences.
The Politecnico di Milano has established two new laboratories, MINERVA and ATHENA, to study the microbiota-gut-brain axis. These labs will develop organ-on-a-chip devices that model in vitro the organs involved in this complex interaction.
Scientists have identified a link between gut microbiota and brain cell communication, revealing altered gene expression in immune cells that disrupts learning processes. Restoring gut microbiota at birth rescues learning deficits, suggesting early-life signals play a crucial role.
Studies show intestinal bacterial imbalance linked to neurodegenerative diseases like Alzheimer's Disease and traumatic brain injury. Probiotics may improve brain function by altering the gut microbiome, reducing amyloid beta plaque and memory deficits.
A large-scale study found that vaginally born babies have different gut bacteria than those delivered by Caesarean. Researchers discovered that the mode of delivery impacted the gut microbiome, with vaginal delivery promoting mother's gut bacteria and Caesarean deliveries resulting in hospital-borne bacteria.
A 16-week vegan diet was shown to increase the abundance of Faecalibacterium prausnitzii and Bacteoides fragilis, leading to significant reductions in body weight, fat mass, and visceral fat. Insulin sensitivity also improved in the vegan group.
A team of researchers investigated the link between pregnancy and lupus flares, finding that gut microbiota may regulate disease severity. The study suggests that modulating the gut microbiota community could lead to improved disease management for pregnant women with lupus.
A study found abnormal gut microbiota in veterans with PTSD and cirrhosis is tied to poorer cognitive performance. The research also identified beneficial bacteria like Ruminococcaceae as associated with better performance.
A study found that premature babies' gut microbiomes remain disrupted after antibiotic treatment, leading to an increased risk of disease and health problems later in life. The research suggests that minimizing antibiotic use in preemies may help prevent these issues.
Researchers discovered that providing native foods to captive rodents preserves their gut microbiome diversity, whereas artificial diets lead to significant changes. The study found that feeding woodrats with prickly pear cactus maintained around 90% of their original microbiome diversity.
Researchers found a modified Mediterranean-ketogenic diet altered gut microbiome and reduced Alzheimer's markers in participants with mild cognitive impairment. The study suggests that specific gut bacteria changes may impact dementia development.
A study found that bacteria in coronary plaques were pro-inflammatory, whereas gut bacteria were diverse and varied. Patients with acute coronary syndrome had different gut microbiota compared to those with stable angina. The research suggests a possible role for microbes in plaque destabilization and heart attack onset.
Researchers found that faecal inoculations changed the koalas' microbiomes, allowing them to eat messmate. This could affect all aspects of their ecology, including nutrition and habitat selection. The study provides a proof of concept for using encapsulated faecal material to introduce new microbes in koalas' guts.
Long-term survivors of pancreatic cancer have a diverse tumor microbiome, which boosts their immune attack on tumors. Fecal transplant treatments can alter the tumor microbiome, suggesting a potential therapeutic opportunity for improving pancreatic cancer treatment.
Researchers at University of Utah Health identified a specific class of gut bacteria called Clostridia that prevents mice from becoming obese. Giving these microbes back to mice with an impaired immune system allows them to stay slim, suggesting a potential therapeutic approach for humans.
Researchers created a diet that can help restore digestive tracts damaged by acute childhood malnutrition, supporting growth and functioning. Protein-rich plant foods like chickpeas, bananas, and peanut flours were found to support microbial transition and increase protein biomarkers related to child development.
A new computational modeling method, MTV-LMM, predicts how the gut microbiome will change over time by analyzing snapshots of microbes found in a person's gut. This could lead to better diagnosis and treatment of diseases, as well as insights into other types of temporal microbiome processes.
Researchers found that gut microbiota influences morphine tolerance, with tolerant mice lacking Bifidobacteria and Lactobacillaeae. Probiotics restored these depleted communities, reducing morphine tolerance in mice pretreated with probiotics.
Critically ill children with reduced numbers of 'good' bacteria and decreased levels of beneficial chemicals have a higher risk of organ failure. Chemical analysis revealed dramatic depletion of certain bacterial compounds, including hippurate, formate, and 4-cresol sulphate.
A recent review of studies found that regulating intestinal microbiota through probiotics and non-probiotic interventions can effectively reduce anxiety symptoms in people. Probiotic supplements were only effective in about half of the studies, while non-probiotic interventions showed a 86% rate of effectiveness.
Researchers found that long-term antibiotic treatment alleviates Alzheimer's disease symptoms in male mice by reducing inflammation and slowing amyloid plaque growth. However, the same treatment had no effect on female animals, with changes in the gut microbiome leading to increased proinflammatory factors.
A new study found that titanium dioxide nanoparticles, used in over 900 food products, can affect the gut microbiota and potentially trigger diseases like inflammatory bowel diseases and colorectal cancer. The research suggests that better regulation of E171 consumption is needed to ensure safe use.
Researchers found that a diet enriched with ω-3 PUFAs and vitamin A can normalize gut microbiome composition and hippocampal protein levels, leading to improved emotional and memory performance in stressed rats. The study also suggests long-term links between diet and cognitive function.
Research suggests that mode of delivery influences the development of the gut microbiota in infants, with C-sections linked to delayed bacterial colonization and increased risk of respiratory infections. This may have implications for future respiratory health.
A study found that a newborn's first stool microbiome is linked to their risk of becoming overweight at age 3. Infants exposed to antibiotics during infancy had altered gut bacteria populations, which may contribute to long-term weight gain.
The study reveals that dietary phytoestrogens are metabolized by the gut microbiota of southern white rhinoceroses, leading to infertility. The researchers also found species differences in estrogen receptor sensitivity to phytoestrogen metabolites.
A new study found that Microbiota Transfer Therapy (MTT) led to significant improvements in autism symptoms and gut health, persisting even two years post-treatment. Parents reported slow but steady reductions in ASD symptoms over time.
A recent study has found that garlic can protect memory by improving gut health, which is associated with age-related memory problems. The researchers observed that mice receiving the garlic compound showed better long- and short-term memory than those not receiving the treatment.
Researchers have established disease-specific microbiome changes that are globally robust, despite differences in environment, diet, and lifestyle. These findings provide a basis for future non-invasive cancer screening and may enable new research into the causal role of gut microbes in colorectal cancer development.
Researchers at UC San Diego identified unique bacterial features in the stool of people with nonalcoholic fatty liver disease and their twins, allowing for 92% accurate diagnosis of liver cirrhosis. The test also showed promise in detecting previously undiagnosed cases with 87% accuracy.
A new study found that probiotic bacteria can evolve and change inside the mouse's gut, making them less effective and sometimes harmful. The researchers discovered that the bacteria's DNA changes and they develop new capabilities after living in the mice's intestines for a few weeks.
Researchers discovered that knocking out NLRP6 protein in mice led to better survival and less severe symptoms after bone marrow transplant. The study also found that NLRP6 played a non-microbiome dependent role in GVHD, suggesting potential therapeutic targets for reducing its effects.
Research suggests that an aging microbiome may be the key to understanding vascular decline and cardiovascular disease risk. The study found that suppressing the microbiome in old mice restored vascular health to that of young mice, highlighting the potential for gut-friendly diets and supplements.
A recent study by WVU researchers found that stroke patients' microbiomes may still be out of balance a month after the stroke has passed. The team discovered changes in the structure of their guts, including less prominent beneficial bacteria and increased inflammation.
The microbiota controls neutrophil activity by producing Serum Amyloid A (Saa), a host protein that restricts aberrant activation while enhancing migration to wounds. Saa reduces bactericidal activity and expression of pro-inflammatory genes in neutrophils.
A study by researchers from Charité - Universitätsmedizin Berlin has identified a molecule, c-Maf, that regulates the balance between the immune system and gut microbiota. This finding may lead to new therapies for chronic inflammatory bowel disease.
A researcher at Georgia State University is studying how dietary fiber can protect against diabetes and other metabolic disorders. The study aims to develop new strategies to maintain a healthy gut-microbiota relationship, which could enable safe treatment and prevention of type 2 diabetes.
Research suggests that higher cardiorespiratory fitness is associated with greater gut microbiota diversity, independent of body fat percentage. The study found that exercise at a high intensity improved gut microbiota diversity in cancer survivors.
The study, published in JAMA Network Open, demonstrates that an individualized approach to diet considering a person's unique gut microbiome is more accurate in predicting blood glucose response to food. The research found that this approach was superior to traditional models based on carbohydrates or calories.
A recent study analyzed the gut microbiomes of ethnically diverse Africans from seven populations, revealing wide ranges of microbiome profiles. The researchers found that while there were differences between industrialized and non-industrialized populations, there were also unexpected similarities between groups.
A study found that fruit flies with a full microbiome can choose to feed on larger but less nutritious droplets of food, whereas those without gut bacteria are limited to smaller droplets containing essential amino acids. This allows scientists to develop strategies to control invasive pests.
This special issue of Clinical Gastroenterology and Hepatology delves into the relationship between the gut microbiome and specific digestive diseases. Key findings include the role of the microbiome in inflammatory bowel disease, functional gastrointestinal diseases, colorectal cancer prevention, and pancreatic disease.
A study of over 1,700 individuals found distinct gut microbiome compositions between IBD and IBS patients. The results may help identify new therapeutic targets for these gastrointestinal disorders.
Researchers discovered that tropical fish control their gut microbes to better survive extreme temperatures. The host's genetic background influences the microbiome's composition and response to temperature, with cold-resistant fish having a distinct core group of tolerant microbes.
Researchers found fecal microbiota transplantation (FMT) to be an effective treatment for severe colitis caused by immune checkpoint inhibitors. The study showed both patients experienced significant improvements in inflammation and ulcerations after FMT, with reduced resemblance to their own pre-treatment gut microbiome.
New NYU Abu Dhabi research suggests corals produce molecules that can help resist disease by maintaining healthy surface microbiomes. The study found unique molecules at the surface of Acropora and Platygyra corals, which may structure beneficial microbial communities and defend against parasitic bacteria.
Researchers at Sahlgrenska Academy discovered that gut microbiota in people with type 2 diabetes produces a substance impairing insulin response. This finding highlights the importance of diet and gut microbiota interaction in understanding metabolism in health and disease.
Research reveals that babies establish a healthy gut microbiome until around 2.5 years old, with breastfeeding playing a crucial role in early life. After weaning, the microbiome rapidly changes and becomes more stable, but the loss of beneficial bacteria can occur if breast milk is not available.
A recent study suggests that infant gut microbiota composition at 2 years of life is associated with body mass index (BMI) at age 12. The researchers found a stronger relationship between gut microbiota taxa and BMI z-scores as the kids got older, indicating that gut microbiota may be an early warning sign for detecting obesity.
Research found that six weeks of endurance exercise altered the gut microbiota, decreasing inflammation-causing Proteobacteria and increasing Akkermansia, a genus linked to enhanced metabolism. Exercise also improved cardiometabolic health by reducing VLDL particles.