Articles tagged with Gut Microbiota
A team of researchers from Penn State found that the microbiomes of warblers are influenced more by evolution than diet, contrary to a recently proposed hypothesis. The study's results suggest that evolutionary history plays a larger role in determining the diversity of bacteria within birds' gut microbiomes.
A team of researchers discovered that the gut microbiome plays a critical role in driving granulopoiesis, a process formation of granulocytes, in mice models. The study found that alterations in the gut microbiome composition induced by neutropenia stimulate reactive granulopoiesis via interleukin 17A secreted by T cells, promoting neu...
A new study by CHOP researchers found that antibiotic-resistant Enterococcus enhances C. difficile virulence by modulating the gut environment, increasing toxin production and nutrient supply. This interaction supports increased colonization and persistence of C. difficile in the gut.
A new study on rhesus macaques reveals a strong link between social connections and the abundance of beneficial gut bacteria. Monkeys with more sociable behavior have a higher presence of microbes like Faecalibacterium, which has anti-inflammatory properties.
Research found tomatoes increased gut microbiome diversity and shifted bacteria toward a more favorable profile in young pigs. The findings suggest a potential link between tomato consumption and improved health outcomes in humans.
Researchers found distinct gut microbiomes in wild marten from pristine and heavily impacted areas, highlighting a tool for assessing ecosystem health. The study's findings suggest that human disturbance affects carnivores' diets, reflected in their gut microbiomes.
A new study found that COVID-19 infection directly interferes with the healthy balance of microbes in the gut, further endangering patients. The research revealed that antibiotic-resistant species can escape into the bloodstream, putting patients at greater risk for life-threatening secondary infections.
Zebrafish studies reveal a key role of gut microbes in shaping brain circuits responsible for social behavior. The findings suggest a possible translation to mice and humans, offering new insights into neurodevelopmental disorders such as autism spectrum disorder.
Research reveals that common gut bacteria enhance cocaine effects in mice by consuming glycine, leading to behavior abnormalities. Supplementing glycine or using a genetically modified bacteria reduces response to cocaine, demonstrating its role as an addiction mediator.
A randomized clinical trial found that applying topical antibiotics to the upper digestive tract can improve survival rates in mechanically ventilated intensive care patients. The study, published in JAMA, also showed a significant reduction in new hospital-acquired infections.
Researchers explore the role of nutrition in cancer development, finding that precise nutritional strategies can be used to supplement treatment and treat cancer. Intermittent fasting is being studied as a promising approach to fight cancer, with studies showing it may increase toxicity on tumour cells and reduce side effects.
A new study published in the European Respiratory Journal found that early treatment with anti-anaerobic antibiotics can deplete gut anaerobes and lead to worse clinical outcomes. The research suggests that these 'good bugs' protect against pneumonia, organ failure, and mortality.
A Baycrest study found that the gut microbiome plays a role in how diet and exercise affect brain health and dementia risk. Lifestyle interventions like Mediterranean-style diets can improve cognition and promote healthier microbiomes.
The event will cover various topics including microbiota dysbiosis, oral and vaginal microbiota, and their impact on diseases like depression, cancer, and respiratory infections. The meeting aims to accelerate Microbiota medicine applications through strategic discussions.
Researchers identified a specific gut bacterium responsible for antibiotic-induced GVHD after stem cell transplants. A sugar supplement was found to improve gut health by distracting the bacteria from attacking mucin in the intestinal lining, reducing complications such as GVHD.
Researchers found that Fecal Microbiota Transplant (FMT) using capsules has a cure rate of 86% at one month and 81% at two months for recurrent CDI, comparable to colonoscopic FMT. Patient selection is key to optimizing FMT success.
Researchers found pre-existing differences in gut bacteria between people with and without HIV, including decreased Bacteroides species and increased Megasphaera elsdenii. These changes were present even before infection occurred, suggesting a potential link between gut microbiome and HIV susceptibility.
The Center for Health Equity Research at NAU has received a $21 million grant from NIH to continue its work on health disparities among diverse populations. The grant will fund dozens of projects over five years, focusing on increasing basic research opportunities and access to resources for underrepresented communities.
Researchers at the University of Toledo found that consumption of highly refined fiber may increase liver cancer risk in some individuals, particularly those with a silent vascular deformity. The study discovered that high concentrations of bile acids caused by a portosystemic shunt led to the development of liver cancer.
A new study conducted by researchers from Aarhus University and Aarhus University Hospital shows that fecal transplantation is an effective cure for life-threatening intestinal infections, with a cure rate of over 90%. The treatment was found to be far superior to the standard treatment, which typically consists of antibiotics.
A recent study of Alaskan brown bears reveals that their gut microbiomes play a crucial role in supporting health and achieving comparable size despite eating vastly different diets. The research sheds light on the importance of diverse dietary niches for bears, which can help them extract nutrition from various food sources.
Researchers at UMC Utrecht will investigate how intestinal microbiota impacts cancer immunotherapy and therapy side effects. The project aims to develop microbiota-targeted therapies to improve ICI treatment effectiveness and reduce severe inflammation.
Researchers found that transplanted gut bacteria from mice with obstructive sleep apnea caused increased blood pressure and impaired coronary function in recipient mice. Probiotics improved symptoms for the recipients but not the donor mice, highlighting a potential therapeutic strategy to mitigate cardiovascular disease.
Researchers at Stanford University have created a synthetic microbiome comprising over 100 bacterial species, successfully transplanted into mice and demonstrated protection against E. coli infection. The team's achievement enables the study of specific bacteria contributing to health benefits, ultimately leading to the development of ...
Research found that air pollution exposure in the first six months of life impacts a child's inner world of gut bacteria, increasing risk of allergies, obesity, and diabetes. The study also suggests that exposure to pollutants can influence brain development.
Researchers found that Morinda officinalis oligosaccharides increase serotonin production in the gut microbiota, alleviating depression. The study revealed a significant anti-depressant effect through promoting 5-hydroxytryptophan production in the gut microbiota.
A study published in Cell found that a Western-style diet high in sugar alters the gut microbiome, leading to metabolic disease, pre-diabetes, and weight gain. Eliminating sugar from the diet restored the protective effects of Th17 immune cells, which were depleted by the sugar.
Extracellular vesicles and exosomes are membrane-bound vesicles that facilitate intercellular exchange of proteins, lipids, and genetic material. They will be highlighted in upcoming events focusing on mitochondrial quality control, skin ageing, and microbiota.
Gut epithelial cells control mutualism between host immune system and gut microbiome by regulating SFB and Th17 cell levels. Lack of IκBζ gene impairs defense mechanisms against pathogens, leading to inflammatory diseases.
A substance produced by gut microorganisms, TMAO, can lead to scarring and vascular damage in scleroderma. The Western diet rich in meat contributes to TMAO formation, which reprograms cells to become scar-forming myofibroblasts.
Researchers create polymeric micelles that deliver butyrate, a compound produced by healthy gut bacteria, to restore the gut's protective barrier and microbiome. The treatment prevents life-threatening anaphylactic responses in mice with peanut allergies.
A study published in Frontiers in Immunology found that Japanese herbal medicine DKT reduces colitis severity by preventing gut bacteria loss and increasing immune cells. It restores Lactobacillus levels and promotes type 3 innate lymphoid cells, alleviating inflammatory responses.
A new study suggests that acetate produced by the liver diffuses into the intestines, supporting bacterial growth and causing imbalanced microbiota. This imbalance does not appear to play a major role in alcoholic liver disease risk.
Research found that breastfed premature infants have improved gut barrier function and nutrient absorption due to the presence of Bifidobacterium breve. This strain strengthens the intestinal wall, protecting against disease. The discovery could lead to promising clinical interventions to increase survival rates of vulnerable preemies.
A new study from the University of Illinois found that dog gut bacteria can change rapidly after introducing a new diet, with microbial turnover occurring in under a week. The research also confirmed previous findings on the health benefits of high-fiber diets over high-fat and high-protein diets.
Research from Anglia Ruskin University found that microbial instability in the gut hinders endurance athlete performance. High-carbohydrate diets were associated with improved time trial performance, while a short-term high-protein diet led to reduced time trial performance by 23.3%.
A new study explores relationships between domestic cats' hormone levels, gut microbiomes, and social behaviors in cohabitating groups. The research found that low testosterone and cortisol concentrations enabled cats to share space, while high oxytocin levels were associated with less affiliative behavior.
Researchers discovered a specific gut bacterial strain, Klebsiella aerogenes, that produces histamine and triggers abdominal pain in IBS patients. The study found that reducing histamine production by colonizing mice with low fermentable carbohydrates led to decreased pain.
Gut bacteria produce inositol lipids, vital for cellular processes in humans, and these substances impact the symbiosis between bacteria and their hosts. The discovery sheds light on how gut bacteria thrive in their human hosts.
A study published in Cell Reports found that a rhythmic small intestinal microbiome prevents obesity and type 2 diabetes in mice. The researchers used mouse models to explore how diet and feeding patterns affect the gut microbiome and its impact on host health, particularly with obesity and type 2 diabetes.
A team of ecologists from CU museum identified over 7,000 organisms, mostly bacteria, in the guts of Rocky Mountain snails collected between 1920 and 2018. The findings show that microbiomes can offer insights into how animals interacted with their environments centuries ago.
Researchers at Georgia State University developed a personalized treatment to prevent ulcerative colitis in mice by modifying gut microbiota. The study found that orally administering metabolites from treated microbiota provided strong protection against chronic inflammation.
A new study published in iScience found that the co-development of the gut microbiome, immune system, and respiratory system is correlated with a baby's respiratory health. Disruption of any of these systems resulted in greater respiratory morbidity for infants, highlighting the importance of timing in intervening with therapies.
Researchers sequenced the whole genomes of three species of carpenter bees, gaining insights into their gut microbiome, diet, and viral load. They found beneficial bacteria, including Lactobacillus, which protect against fungal pathogens and boost the immune system.
Researchers at MD Anderson Cancer Center found distinct gut microbiome signatures associated with immunotherapy response in patients with newly diagnosed glioblastoma. The study identified a link between gut microbiome signatures and immune checkpoint blockade response in melanoma, NSCLC, and sarcoma.
Research reveals antibiotics can knock out essential gut bacteria, leading to reduced motivation and endurance in athletes. The study found that high-performance mice were more affected by antibiotic treatment, highlighting the microbiome's impact on exercise behaviors.
A recent study published in eLife found that wildlife living in urban environments have picked up some gut bugs from humans, leading to a 'humanization' of their microbiota. The researchers analyzed gut microbiomes in distantly related vertebrates from urban and rural areas and discovered significant differences between the two.
Researchers from UToledo found that a dominant gut bacteria species, Coprococcus comes, can break down quinapril and ramipril, reducing their efficacy. This study provides insights into the impact of gut bacteria on blood pressure medication, potentially leading to new ways to overcome treatment-resistant hypertension.
A new study found that exposure to dogs, particularly from ages 5 to 15, was linked to healthy gut permeability and balance in the gut microbiome. Additionally, growing up in a large family with three or more siblings may also provide protection against Crohn's disease by influencing microbiome composition.
A new study suggests that growing up with dogs and in large families may lower the risk of inflammatory bowel disease. Exposure to dogs, particularly between ages 5-15, was linked to healthy gut permeability and a balanced immune response, which may help protect against Crohn's disease.
A randomized clinical trial found that a specific probiotic supplement accelerated the maturation of the microbiome in extremely preterm infants, leading to reduced intestinal inflammation and improved feeding tolerance. The study also showed potential benefits for reducing the risk of food allergies in these vulnerable infants.
Scientists estimate 20% of children and 26% of adults in the US consume high levels of live microorganisms daily. These findings suggest a link between dietary microbes and health outcomes, highlighting the importance of quantifying live microbes consumed through food and supplements.
A recent study published by the Murdoch Children's Research Institute found no significant association between caesarean birth and the development of food allergies in infants. The research involved over 2,000 infants and suggested that babies born via caesarean delivery are not at a higher risk of developing food allergies.
Scientists discovered that commensal fungi like Candida albicans need to be alive and actively producing proteins to elicit a beneficial immune response. The fungus oscillates between high and low expression of the UME6 gene, signaling its benefits to the body.
Researchers found microbes influence which genes are used for fat digestion and absorption, leading to changes in epithelial cells. The study also showed microbes promote lipid absorption and impact systemic processes like weight gain.
The study found that gut microbiota releases membrane vesicles containing bacterial DNA, which triggers the cytosolic cGAS-STING-IFN-I axis to protect distal organs against viral infections. Antibiotic treatment impairs this ability, making mice more susceptible to viral infections.
Researchers discovered a link between traumatic brain injuries and changes in the gut microbiome, suggesting a potential diagnostic tool for concussions. The study found two bacterial species that dropped significantly after concussions, indicating a correlation with traumatic brain injury-linked proteins in the blood.
A new study suggests that supplementing a diet with Ascidiacea, also known as sea squirts, reverses some main signs of aging in animal models. The researchers found that plasmalogens, vital to body processes, decrease with age and contribute to neurodegenerative diseases like Alzheimer's and Parkinson's.
A new study reveals that recurrent urinary tract infections (UTIs) may be caused by an imbalance in the gut microbiome, which can lead to chronic inflammation and increased risk of future UTIs. Antibiotics given to treat UTIs can disrupt the microbiome, making it easier for disease-causing bacteria to spread.
Scientists have found that transplanting faecal microbiota from young mice into old mice can reverse hallmarks of ageing in the gut, eyes, and brain. The study suggests that gut microbes play a role in regulating some of the detrimental effects of ageing, offering a potential solution in the form of gut microbe replacement therapy.