Articles tagged with Gut Microbiota
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
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Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found fecal transplants increase IL-25, reducing tissue inflammation and boosting immune system response to C. difficile infections. The transplants also promote beneficial microbial diversity, helping patients heal from life-threatening diarrhea.
A new study published in the journal Nutrients found that probiotics can reduce nausea and vomiting during pregnancy by up to 33% and improve quality of life symptoms. The study also identified specific gut microbes associated with higher levels of nausea, suggesting potential biomarkers for future research.
Researchers found that adding a specific bacterium to the gut microbiome of mice with colon cancer increased immune cell activity and reduced tumor size. The study suggests leveraging gut microbiota to enhance anti-tumor immunity in advanced colon cancer, offering a promising new approach for treatment.
Researchers have discovered that certain microbes can prevent Clostridioides difficile infection by consuming nutrients essential for its growth. This new understanding challenges existing approaches to probiotic treatment options, which focus on restoring secondary bile acids.
A new study has shed light on the gut microbiome of gorillas, revealing significant diversity among individuals and institutions. The research found that even healthy gorillas can have unique microbial profiles, emphasizing the importance of understanding individual context for health assessment.
Research found that proton pump inhibitors (PPIs) may reduce the effectiveness of immune checkpoint inhibitor drugs in patients with non-small-cell lung cancer. PPI use was associated with worse survival rates and a significant decrease in the benefit of immune therapy treatment.
Researchers discovered that these 'meat-eating' bees have a unique gut microbiome enriched with acid-loving bacteria, similar to those found in vultures. The bees' ability to eat dead bodies is surprising, but they can also store honey and have special chambers for meat storage.
Research identifies two distinct microbial signatures in irritable bowel syndrome (IBS) patients, with one showing a significant response to the low FODMAP diet. The study found that patients with the pathogenic-like signature experienced improved symptoms after adopting the diet.
A new study published in Gut Microbes found that exercise intervention reduced pain and lowered inflammatory substances in people with arthritis. Exercise increased levels of cannabis-like substances called endocannabinoids, which may help treat certain conditions.
A University of Utah team analyzed woodrat gut bacteria and found that evolutionary history plays the greatest role in shaping microbiome structure. Diet and geography also influenced microbiome composition, but host relatedness was the strongest predictor in both wild and captive populations.
University of Calgary researchers have discovered specific microbial factors that help regulate the enteric nervous system, which controls the gastrointestinal tract. This finding may lead to novel ways to treat gastrointestinal disorders such as irritable bowel syndrome and inflammatory bowel disease.
A study found that children with autism tend to have less diverse diets and lower gut microbiome diversity compared to their non-autistic peers. This suggests that dietary preferences may contribute to the development of autism-related traits.
A new clinical study found that grape consumption increased gut bacterial diversity and reduced cholesterol levels, including total cholesterol by 6.1% and LDL cholesterol by 5.9%. This suggests a potential role for grapes in promoting good gut health and supporting heart health.
Researchers found diet-associated molecules in the gut are associated with aggressive prostate cancer, linking them to higher levels of metabolites like phenylacetylglutamine and nutrients choline and betaine. The study's findings may have clinical implications for diagnosing and preventing lethal prostate cancer.
A recent study published in Annals of the Rheumatic Diseases reveals a link between systemic lupus erythematosus and an altered gut microbiome. Researchers at Osaka University identified two species of Streptococcus bacteria significantly increased in SLE patients, which can affect the body's functions by altering plasma metabolites. T...
A study found that infant formula is associated with a 70% higher occurrence of antibiotic resistance genes in newborns. Breastfeeding, on the other hand, reduces the proliferation of opportunistic pathogens, potentially lessening the risk of difficult infections.
Cadmium exposure has been linked to an increased risk of developing allergies, particularly asthma, in children. Researchers found that gut bacteria over-produce an enzyme degrading vitamin D after cadmium ingestion, mimicking a deficiency, leading to enhanced allergic reactions.
A recent University at Buffalo study found that patients using proton pump inhibitors (PPIs) for heartburn had smaller probing depths in their gums, indicating less severe gum disease. The researchers suggest that PPIs' side effects may be linked to reduced periodontitis severity.
Researchers at Ben-Gurion University of the Negev have discovered that artificial sweeteners can significantly impair bacterial communication. Three out of six tested FDA-approved sweeteners were found to inhibit quorum sensing, a key process for bacteria to communicate with each other.
Researchers tracked individual Kirtland's Warblers and found that their gut bacteria differed in The Bahamas and Michigan. This suggests that birds' microbiomes adapt to changing environments during migration.
A high-fat diet increases the incidence of colorectal cancer by suppressing MHC-II levels in intestinal cells. This disruption allows cancer cells to grow unchecked. Researchers hope that reconfiguring the gut microbiome and boosting immune recognition molecules can help combat cancer.
Studies found distinct patterns in nasal microbiota of individuals infected with SARS-CoV-2, with symptomatic patients showing reduced bacterial counts and increased presence of certain bacteria. The findings suggest that altered microbiota may impact immune response to the virus.
A recent study published in Cell Host & Microbe found that certain gut bacteria are associated with an increased risk of colon cancer. Researchers discovered a correlation between the presence of non-enterotoxigenic Bacteroides fragilis and inflammation in small polyps. The study suggests that normally healthy gut bacteria may adapt to...
A new study by Oregon State University finds that xanthohumol improves glucose metabolism in mice only when the gut microbiota is present. The researchers discovered that three specific bacteria, Akkermansia muciniphila, Parabacteroides goldsteinii and Alistipes finegoldii, are responsible for XN's health benefits.
A study by Kazan Federal University found that probiotics administered to antibiotic-treated mice improved behavior, reduced oxidative stress, and restored gut microbiota diversity. The researchers demonstrated a strong link between the gut microbiota and brain functioning, with potential therapeutic benefits for treating dysbiosis-rel...
A high-fat diet causes inflammation and damages intestinal epithelial cells, leading to the growth of harmful microbes and increased production of trimethylamine-N-oxide, a metabolite associated with cardiovascular disease. Researchers found that restoring intestinal function with a drug can blunt this effect.
A study from the University of South Carolina's Environmental Health & Disease Laboratory found that andrographolide successfully restored bacteriomes and viromes, increasing beneficial bacteria and decreasing harmful bacteria. The treatment also decreased gut inflammation and neuroinflammation in veterans with Gulf War Illness.
Researchers found that fasting decreases signs of bacterial infection and inflammation in mice. Fasting also alters gut microbiomes, which appear to sequester nutrients and prevent pathogens from infecting the host.
A Rutgers study suggests that newborns at risk for Type 1 diabetes due to antibiotic exposure can have their condition reversed by receiving a maternal fecal transplant. The transplant restored key gut microorganisms and brought diabetes risk back to baseline levels.
Researchers from Tokyo Medical and Dental University found that IgA deficiency causes substantial inflammation in the ileum of mice, making them susceptible to disease. The study reveals IgA plays a protective role in maintaining gut health by regulating microorganisms.
A University of Alberta study found that infant boys with a high Bacteroidetes gut bacterial composition scored higher in cognition and language skills. The researchers believe this association may be due to the production of metabolites called sphingolipids, which are instrumental for neuron formation and structure.
A longitudinal study of infants at risk of developing celiac disease found increased microbial strains and metabolites associated with autoimmune conditions, while decreased protective effects were observed. These preclinical gut microbiome changes may serve as early markers of disease progression.
Newborns are more susceptible to GBS meningitis due to immature gut microbiota and epithelial barriers. This study highlights the critical role of microbiota in protecting against infection, demonstrating its importance in newborn health.
A study found specific gut microbiota signatures correlate with high-grade adverse events and response to combined CTLA-4 and PD-1 blockade treatment. The research identified a potential new strategy to treat toxicity while maintaining response through IL-1R inhibition or manipulation of the gut microbiota.
Researchers found that most IBS patients have visible bacterial biofilms in their gut under endoscopic examination, which can impair gut function. Biofilms can also occur in ulcerative colitis patients, and irrigation therapy shows promise in alleviating symptoms.
A double-blind trial found that faecal microbiota transplantation did not improve treatment outcomes or reduce symptoms in patients with active peripheral PsA. The study suggests that FMT may not be an effective treatment option for this condition, and future research is needed to explore its potential benefits.
Researchers found that diet can alter the breast microbiome to affect breast cancer risk. The study, published in Cancer Research, showed that a high-fat diet led to more aggressive tumors and reduced effectiveness of fish oil supplements.
A comprehensive review suggests that gut microbiota play a crucial role in immune responses to vaccinations. The study aims to improve vaccine effectiveness by understanding the microbiota's impact on B and T cell immune responses.
Researchers found that intermittent fasting lowers blood pressure by altering the gut microbiota composition. The study suggests that gut dysbiosis contributes to hypertension by changing bile acid signaling.
A study published in eLife found that an overgrowth of yeast in the gut within the first few months of life may increase the risk of asthma later on. The period after birth is critical for immune system development and gut microbiome health, and disruptions to gut bacteria can lead to asthma.
Researchers have found a causal link between caesarean section birth and peanut sensitivity in infants, with effects more pronounced in children of Asian descent. Infants born by C-section were eight times more likely to develop peanut allergy by age three compared to those born vaginally.
Research found high dietary intake of animal products, processed foods, and sugary drinks is linked to an 'inflammatory' gut microbiome. Conversely, a diet rich in plant-based foods may promote 'friendly', anti-inflammatory microbes that help control inflammation.
Researchers at UC Santa Barbara have deciphered the composition and function of sea urchin microbiomes, revealing significant differences between red and purple species and habitats. The study suggests that sea urchins may be able to produce their own food using microbes in their guts.
A new study has demonstrated a correlation between autism spectrum disorder and changes in the gut microbiome. The researchers found that individuals with autism exhibited differences in gut microbiome composition compared to neurotypical controls, with gastrointestinal symptoms being significantly higher in those with autism. Longitud...
Researchers found that high-fiber compounds reduced the expression of a gene and cytokine receptor involved in viral cell entry and inflammation. The findings suggest that high-fiber diets may help control inflammation caused by COVID-19, which can lead to gastrointestinal symptoms and changes in gut microbiota.
A new review published in the Journal of Dairy Science suggests that fermented milks may help reduce hypertension by modulating gut microbiota. The researchers propose the development of tailor-made fermented milks to target this effect, which could have significant implications for cardiovascular health.
A new study found that exposure to antibiotics within the first 14 days of life is associated with reduced weight and height in boys up to age six. However, antibiotic use after neonatal period leads to higher body mass index (BMI) in both boys and girls during childhood.
Researchers at Monash University have discovered two novel molecules that provide profound protection in experimental models of asthma and reduce the severity of asthma attacks. These molecules, including one commercially available as a dietary supplement, also show promise in treating respiratory illness associated with COVID-19.
A recent study found no association between gut fungi and Parkinson's disease, contrary to previous studies on the bacterial microbiome. The researchers analyzed fecal samples from 95 PD patients and 57 controls, concluding that fungi were sparse in the gut microbiomes of PD patients.
Researchers found that gut microbes in anorexia patients are less diverse and more abundant in 'harmful' species. Transferring fecal samples from anorexia patients to mice resulted in similar symptoms, suggesting a link between gut bacteria and anorexia symptoms. Targeting the microbiome may be a viable treatment for anorexia.
Research suggests that COVID-19 severity may be influenced by the composition of the gut microbiome, with certain bacteria contributing to inflammatory responses. The study found that patients with COVID-19 had altered gut microbiota compared to healthy individuals, including lower levels of beneficial species.
A large-scale international study found strong associations between specific gut microbes, dietary habits, and cardiometabolic disease risk. Participants who consumed a healthy, plant-based diet had higher levels of beneficial gut microbes.
Research reveals that an imbalance in gut bacteria can cause depressive-like behaviors by reducing essential lipid metabolites. Transferring healthy gut bacteria from one animal to another can restore normal brain function and alleviate depression.
Researchers analyzed ten cancer patients with refractory melanoma and found that fecal microbiota transplant improved patient outcomes in three out of ten cases. The treatment was safe and feasible, suggesting a potential role in overcoming resistance to anti-PD-1 immunotherapy.
Research reveals significant microbial changes in women with polycystic ovary syndrome, associated with metabolic health. The study also found differences in microbiome profile between pre-diabetic and healthy women, shedding light on the causes of the condition.
Researchers identified distinct gut microbiome signatures in individuals with major depressive disorder (MDD), including higher levels of Bacteroides and lower levels of Blautia. A biomarker-based diagnostic tool may help physicians diagnose MDD, providing a companion to clinical interviews.
Researchers discovered that black bears' gut microbiomes are surprisingly simple and consistent throughout the intestinal tract. This finding has practical applications for wildlife researchers, as a fecal sample can provide insight into the entire gut microbiome.
Researchers found significant differences in gut microbiome and metabolite profiles between COPD patients and healthy individuals. The study suggests that stool sampling could be used to non-invasively diagnose and monitor for COPD.
A European study confirms that altered intestinal microbiota increases the production of imidazole propionate, a molecule that prevents insulin's blood sugar-lowering effects. Elevated levels of imidazole propionate are also found in prediabetes, suggesting it may contribute to disease progression.
Researchers found that children born by caesarean section have an increased risk of developing asthma if their gut microbiota still carries a caesarean signature at age 1 year. This study proposes restoring the perturbed microbiome to potentially prevent asthma development in high-risk children.