Articles tagged with Gut Microbiota
The Experimental Biology (EB) 2022 meeting features live presentations and a moderated Q&A session on groundbreaking studies. The virtual press conference reveals potential treatments for Parkinson's disease, COVID-19 vaccine-associated side effects, and alleviating food allergies.
A study of nearly 15,000 US nurses found that significant antibiotic use in midlife is associated with increased risk of cognitive decline later in life. The researchers suggest that this may be related to changes in the gut microbiome, which can impact brain function and overall health.
Researchers at Université Laval found that yogurt's health benefits for obesity may be due to its impact on the gut microbiota and production of branched chain hydroxy acids (BCHA). The study, published in Nature Communications, suggests that BCHA can help improve fasting glucose and liver function in obese mice.
A new tool called vibration of effects (VoE) has been developed to analyze the reliability of reported links between gut microbes and various diseases. The tool found that a third of reported microbe-disease associations were inconsistent, with outcomes changing depending on study design and variable inclusion.
A recent study published in Nature Medicine has confirmed the link between a healthy gut microbiome and the response to cancer immunotherapy. The study found that certain bacterial species, such as Bifidobacterium pseudocatenulatum, Roseburia spp., and Akkermansia muciniphila, are associated with a better immune response.
Researchers discovered that gut bacteria can awaken dormant viruses by producing colibactin, leading to cell-killing infections. This finding suggests a possible link between colibactin-producing bacteria and cancer, potentially benefiting the bacteria's own survival.
Researchers analyzed the gut microbiome of 1,241 middle-aged individuals and found that about half of the bacterial species were modified by drug treatment, while 75% of disturbances occurred in early stages of overweight and type 2 diabetes. The study suggests that an imbalanced gut microbiome may play a role in heart disease development
A study found that specific bacterial groups from the Lachnospiraceae family were associated with an increased risk of developing type 2 diabetes. The research used machine learning techniques and analyzed fecal samples from a large Finnish population cohort, identifying microbial biomarkers that predicted disease incidence.
A recent study by researchers from Ritsumeikan University found that athletes with a history of sprained ankle showed reduced gut bacteria diversity compared to those without such a history. This suggests that musculoskeletal injury may have a negative impact on the gut microbiota, potentially leading to long-term health consequences.
Researchers discovered that nerves in the intestines regulate gut acidity to maintain a healthy balance of gut bacteria. They used zebrafish with genetic mutations to study the connection between the enteric nervous system and microbial communities.
Researchers at Tel Aviv University found that a specific type of bacteria, Weissella, becomes dominant in the gut microbiomes of locusts when they form swarms. This change may provide the bacteria with an evolutionary advantage, allowing them to spread and infect more locusts.
Prunes have been found to help prevent or delay bone loss in postmenopausal women by reducing inflammation and oxidative stress. This is due to their potential to alter the gut microbiome, which can lead to lower levels of pro-inflammatory cytokines and markers of oxidative damage.
Researchers at Oregon Health & Science University have made a groundbreaking connection between the gut microbiome and cognitive decline in an animal model of Alzheimer's disease. Fecal implants induced significant behavioral and cognitive changes in mice, offering new avenues for treating or forestalling dementia.
A UC Davis Health study found that taking bile acids or treatments regulating their production levels can help control psoriasis inflammation. Bile acids inhibited skin inflammation by stopping immune T cells from producing proinflammatory protein IL-17A and blocking immune cell movement to the site.
A University of Ottawa review provides the first field-wide summary of how pesticide exposure affects social bee gut microbiotas. The study found that pesticides disturb microbial communities, leading to a loss of benefits and potential decline in bee health and performance.
Researchers at TUM discover that intestinal bacteria interact with Paneth cells in the gut mucus layer, leading to chronic inflammation. This finding may lead to new treatments for IBD.
Beneficial gut microbes transfer genes to acquire vitamin B12, increasing their ability to survive. This process, called bacterial sex, allows them to form a tube that DNA can pass through to another cell, demonstrating the horizontal gene exchange among microbes.
A new study reveals that microbes in the guts of hibernating ground squirrels play a crucial role in recycling nutrients and maintaining muscle mass. The discovery could have significant implications for humans with muscle-wasting disorders and astronauts on extended space voyages.
A study by UConn Health and Washington University School of Medicine found that eating more meat correlates with worse MS symptoms, altered gut bacteria, and increased immune cells. The research identified key bacteria and metabolites associated with the disease, providing new insights into its causes.
Researchers found a distinct microbial profile associated with long COVID symptoms, including fatigue, muscle weakness, and insomnia. Patients with long COVID had a less diverse and abundant gut microbiome compared to those without the condition.
A study found that a daily supplement of urolithin A improved muscle function and reduced inflammation in older adults. The supplement, produced by gut bacteria, was shown to stimulate mitophagy, a process that recycles damaged mitochondria.
Researchers discovered that Black women have a greater relative abundance of Actinobacteria, associated with reduced insulin sensitivity and elevated inflammation. The study highlights the importance of understanding the role of gut microbiome in cardiometabolic health disparities among Black women.
Researchers found that giant pandas' gut microbiota shifts in season, helping them gain weight and store fat. The team used a fecal transplant experiment to show that the metabolic product of Clostridium butyricum can upregulate lipid synthesis and storage.
A recent study reveals significant differences between the gut microbiomes of male and female American minks, suggesting a surprising sexual distinction in carnivores. The findings have implications for future wildlife research, as analyzing fecal samples may not provide accurate assessments of population sex.
A recent study by researchers at Case Western Reserve University found that Candida tropicalis fungus can trigger chronic inflammation in the gut microbiome of Crohn's disease patients. This imbalance of fungi and bacteria can create a predisposition to inflammatory bowel disease.
Patients with sufficient fiber intake had improved progression-free survival and response to immunotherapy in melanoma. A high-fiber diet was associated with slower tumor growth and increased CD4+ T cells in pre-clinical models, supporting the potential benefits of dietary interventions on cancer treatment outcomes.
A high-fiber diet has been shown to improve the response of melanoma patients to immunotherapy by influencing the gut microbiome. Patients who consumed at least 20 grams of dietary fiber per day lived longer without their cancer progressing, compared to those who consumed less fiber.
A study published in Annals of the Rheumatic Diseases found that crAss-like phages, a component of the gut virome, are less abundant in individuals with autoimmune diseases. This discovery may lead to the development of targeted therapies to manage autoimmune conditions.
Researchers found high levels of toxic metabolites produced by gut bacteria in MS patients' cerebrospinal fluid and plasma. The discovery suggests a potential therapeutic target for developing new MS therapies.
Researchers found fecal transplants increase IL-25, reducing tissue inflammation and boosting immune system response to C. difficile infections. The transplants also promote beneficial microbial diversity, helping patients heal from life-threatening diarrhea.
A new study published in the journal Nutrients found that probiotics can reduce nausea and vomiting during pregnancy by up to 33% and improve quality of life symptoms. The study also identified specific gut microbes associated with higher levels of nausea, suggesting potential biomarkers for future research.
Researchers have discovered that certain microbes can prevent Clostridioides difficile infection by consuming nutrients essential for its growth. This new understanding challenges existing approaches to probiotic treatment options, which focus on restoring secondary bile acids.
Researchers found that adding a specific bacterium to the gut microbiome of mice with colon cancer increased immune cell activity and reduced tumor size. The study suggests leveraging gut microbiota to enhance anti-tumor immunity in advanced colon cancer, offering a promising new approach for treatment.
A new study has shed light on the gut microbiome of gorillas, revealing significant diversity among individuals and institutions. The research found that even healthy gorillas can have unique microbial profiles, emphasizing the importance of understanding individual context for health assessment.
Research found that proton pump inhibitors (PPIs) may reduce the effectiveness of immune checkpoint inhibitor drugs in patients with non-small-cell lung cancer. PPI use was associated with worse survival rates and a significant decrease in the benefit of immune therapy treatment.
Researchers discovered that these 'meat-eating' bees have a unique gut microbiome enriched with acid-loving bacteria, similar to those found in vultures. The bees' ability to eat dead bodies is surprising, but they can also store honey and have special chambers for meat storage.
Research identifies two distinct microbial signatures in irritable bowel syndrome (IBS) patients, with one showing a significant response to the low FODMAP diet. The study found that patients with the pathogenic-like signature experienced improved symptoms after adopting the diet.
A new study published in Gut Microbes found that exercise intervention reduced pain and lowered inflammatory substances in people with arthritis. Exercise increased levels of cannabis-like substances called endocannabinoids, which may help treat certain conditions.
A University of Utah team analyzed woodrat gut bacteria and found that evolutionary history plays the greatest role in shaping microbiome structure. Diet and geography also influenced microbiome composition, but host relatedness was the strongest predictor in both wild and captive populations.
University of Calgary researchers have discovered specific microbial factors that help regulate the enteric nervous system, which controls the gastrointestinal tract. This finding may lead to novel ways to treat gastrointestinal disorders such as irritable bowel syndrome and inflammatory bowel disease.
A study found that children with autism tend to have less diverse diets and lower gut microbiome diversity compared to their non-autistic peers. This suggests that dietary preferences may contribute to the development of autism-related traits.
A new clinical study found that grape consumption increased gut bacterial diversity and reduced cholesterol levels, including total cholesterol by 6.1% and LDL cholesterol by 5.9%. This suggests a potential role for grapes in promoting good gut health and supporting heart health.
Researchers found diet-associated molecules in the gut are associated with aggressive prostate cancer, linking them to higher levels of metabolites like phenylacetylglutamine and nutrients choline and betaine. The study's findings may have clinical implications for diagnosing and preventing lethal prostate cancer.
A recent study published in Annals of the Rheumatic Diseases reveals a link between systemic lupus erythematosus and an altered gut microbiome. Researchers at Osaka University identified two species of Streptococcus bacteria significantly increased in SLE patients, which can affect the body's functions by altering plasma metabolites. T...
A study found that infant formula is associated with a 70% higher occurrence of antibiotic resistance genes in newborns. Breastfeeding, on the other hand, reduces the proliferation of opportunistic pathogens, potentially lessening the risk of difficult infections.
Cadmium exposure has been linked to an increased risk of developing allergies, particularly asthma, in children. Researchers found that gut bacteria over-produce an enzyme degrading vitamin D after cadmium ingestion, mimicking a deficiency, leading to enhanced allergic reactions.
A recent University at Buffalo study found that patients using proton pump inhibitors (PPIs) for heartburn had smaller probing depths in their gums, indicating less severe gum disease. The researchers suggest that PPIs' side effects may be linked to reduced periodontitis severity.
Researchers at Ben-Gurion University of the Negev have discovered that artificial sweeteners can significantly impair bacterial communication. Three out of six tested FDA-approved sweeteners were found to inhibit quorum sensing, a key process for bacteria to communicate with each other.
Studies found distinct patterns in nasal microbiota of individuals infected with SARS-CoV-2, with symptomatic patients showing reduced bacterial counts and increased presence of certain bacteria. The findings suggest that altered microbiota may impact immune response to the virus.
Researchers tracked individual Kirtland's Warblers and found that their gut bacteria differed in The Bahamas and Michigan. This suggests that birds' microbiomes adapt to changing environments during migration.
A high-fat diet increases the incidence of colorectal cancer by suppressing MHC-II levels in intestinal cells. This disruption allows cancer cells to grow unchecked. Researchers hope that reconfiguring the gut microbiome and boosting immune recognition molecules can help combat cancer.
A recent study published in Cell Host & Microbe found that certain gut bacteria are associated with an increased risk of colon cancer. Researchers discovered a correlation between the presence of non-enterotoxigenic Bacteroides fragilis and inflammation in small polyps. The study suggests that normally healthy gut bacteria may adapt to...
A new study by Oregon State University finds that xanthohumol improves glucose metabolism in mice only when the gut microbiota is present. The researchers discovered that three specific bacteria, Akkermansia muciniphila, Parabacteroides goldsteinii and Alistipes finegoldii, are responsible for XN's health benefits.
A study by Kazan Federal University found that probiotics administered to antibiotic-treated mice improved behavior, reduced oxidative stress, and restored gut microbiota diversity. The researchers demonstrated a strong link between the gut microbiota and brain functioning, with potential therapeutic benefits for treating dysbiosis-rel...
A high-fat diet causes inflammation and damages intestinal epithelial cells, leading to the growth of harmful microbes and increased production of trimethylamine-N-oxide, a metabolite associated with cardiovascular disease. Researchers found that restoring intestinal function with a drug can blunt this effect.
Researchers found that fasting decreases signs of bacterial infection and inflammation in mice. Fasting also alters gut microbiomes, which appear to sequester nutrients and prevent pathogens from infecting the host.
A study from the University of South Carolina's Environmental Health & Disease Laboratory found that andrographolide successfully restored bacteriomes and viromes, increasing beneficial bacteria and decreasing harmful bacteria. The treatment also decreased gut inflammation and neuroinflammation in veterans with Gulf War Illness.
Researchers from Tokyo Medical and Dental University found that IgA deficiency causes substantial inflammation in the ileum of mice, making them susceptible to disease. The study reveals IgA plays a protective role in maintaining gut health by regulating microorganisms.
A Rutgers study suggests that newborns at risk for Type 1 diabetes due to antibiotic exposure can have their condition reversed by receiving a maternal fecal transplant. The transplant restored key gut microorganisms and brought diabetes risk back to baseline levels.
A University of Alberta study found that infant boys with a high Bacteroidetes gut bacterial composition scored higher in cognition and language skills. The researchers believe this association may be due to the production of metabolites called sphingolipids, which are instrumental for neuron formation and structure.