Articles tagged with Gut Microbiota
A new study maps the impact of stressors during pregnancy on the developing fetal brain, revealing a cell atlas and identifying key immune pathways. The research sheds light on how maternal gut-immune disruptions can shape neurodevelopmental disorders in children.
A groundbreaking study from Northwestern University found that changes to the gut microbiome can change the way the brain works across different primate species. The researchers discovered patterns of gene expression associated with conditions like ADHD and schizophrenia in mice with microbes from smaller-brained primates.
A new international study found significant changes in gut bacteria at the onset of inflammatory bowel disease (IBD), a condition that affects the digestive system. The study reveals a loss of beneficial anaerobic bacteria and an increase in oxygen-tolerant bacteria, which may trigger inflammation.
Research reveals that low doses of nanoplastics can alter gut and liver function, with diet playing a key role. The study found that exposure to nanoplastics disrupted fat metabolism and glucose intolerance, especially in mice on Western-style diets.
Estrogen activates previously unknown pathways in the colon, triggering pain and increasing sensitivity to certain foods. This explains why women are more likely to suffer from IBS and provides potential new ways to treat the condition.
A recent rat study found that an individual's genes can shape their own gut microbiome as well as the microbiomes of those they live with. The research identified three new gene-microbe links and demonstrates how genetic influences can ripple through social groups via shared microbes
A UCLA study found that gut microbes are evolving differently in industrialized and non-industrialized parts of the world. Gene variants associated with starch digestion have
Researchers identified a specific type of gut bacteria, Turicibacter, that promotes metabolic health and reduces weight gain in mice. The bacterium produces fatty molecules that are absorbed by the small intestine, improving ceramide levels and preventing excessive weight gain.
The Algae for Health in Food and Pharma summit explores the latest developments in algae cultivation and processing, food innovation, and pharmaceutical applications. The event aims to advance the understanding of algae's health potential and highlight its applications across the food and pharmaceutical sectors.
Researchers have discovered that certain gut bacteria with similar structures to the protective layer of nerves can misdirect the immune system and cause it to attack its own nervous system. This mechanism accelerates the progression of multiple sclerosis.
Researchers have developed a new test that uses microbes to determine the age of termite droppings, allowing for rapid on-site infestation assessments. The study found that the amount of DNA from E. coli bacteria in the pellets decreases significantly over time, with a nearly 190-fold drop by the 12-month mark.
Research reveals that Methanogenic archaea, particularly M. smithii, play a crucial role in postnatal growth retardation by depleting β-hydroxybutyrate levels and inducing liver inflammation. Transplanting fecal microbiome from PGR piglets to mice confirms the same phenotypes.
A new study published in Gut Microbes reveals that married individuals with higher perceived emotional support have a lower body mass index and fewer food addiction behaviors. The study found that oxytocin pathways linking the brain, gut microbiome, and eating behaviors play a crucial role in shaping obesity risk.
Research finds that sorbitol, a common sugar substitute, can induce similar effects on the liver as fructose, leading to steatotic liver disease. The study also shows that gut bacteria play a crucial role in clearing sorbitol, and that excessive consumption can overwhelm them.
Research suggests that owning a family dog during adolescence can boost mental well-being and social support by altering the gut microbiota. The study found that adolescents with dogs had higher mental health scores and lower social problems compared to those without dogs.
Research highlights the connection between fungi and cancer, revealing that fungal microbiome can promote tumour progression and activate immunosuppressive pathways. Modulating the fungal microbiome may enhance antitumour immunity, with preliminary validation from preclinical and clinical trials.
A study by Shinshu University researchers highlights the potential of probiotics, prebiotics, and synbiotics to enhance livestock gut health, immunity, and growth while reducing dependence on antibiotics. The findings support sustainable livestock management and contribute to reducing antimicrobial resistance risks.
Researchers identified a group of metabolites produced in the intestine that travel to the liver and heart, influencing metabolic pathways and insulin sensitivity. The study found that environmental factors can regulate these metabolites, which play a crucial role in obesity and type 2 diabetes.
A large-scale laboratory screening identified 168 chemicals toxic to human-made gut bacteria. Washing fruit and veggies before consumption may help avoid exposure to these pollutants. Researchers developed a machine learning model to predict chemical harm, emphasizing the need for safer industrial practices.
A new review connects gut microbiome imbalances to obesity, metabolic syndrome, and colorectal cancer, highlighting the potential for diet and microbiome-based treatments. The study also explores racial and socioeconomic disparities in microbiome-related diseases, emphasizing the need for inclusive prevention strategies.
A new study at Ohio State University found that adding a prebiotic to rat diets before and after traumatic brain injury (TBI) lowers impulsivity in decision-making tasks. The research suggests that gut dysbiosis may be a causal force behind long-term symptoms after TBI.
A new paper outlines a global coalition dedicated to conserving microbial biodiversity, which accounts for 99% of life on Earth. The Microbial Conservation Specialist Group will develop Red List-compatible metrics, pilot restoration projects, and promote public awareness to ensure microbes are recognized as essential to planetary health.
Researchers found that eating a Mediterranean diet with moderate portions of lean beef did not increase blood levels of trimethylamine N-oxide (TMAO), an emerging indicator of cardiovascular disease risk. This suggests that dietary quality is more important than the amount of beef eaten in relation to heart health.
Researchers found that bifidobacterium can boost cancer treatment by regulating the immune system, reducing inflammation, and supporting anti-tumor responses. The probiotic also helps detoxify carcinogens and convert food-based substances into cancer-fighting agents, offering a promising natural ally for cancer prevention and treatment.
Research reveals that medications can reshape the trillions of microbes in the gut by competing for nutrients, leading to predictable changes in the microbiome. The study provides a framework for predicting how a person's microbial community might change with a given drug, potentially helping scientists find ways to prevent side effects.
A recent study at UC Davis has shown that feeding cows red seaweed can dramatically cut the amount of methane produced, with a 60% reduction in emissions. The research identified specific microbes in the cow's gut that help reduce methane production, opening the door to engineering these microbes for a long-term solution.
Researchers conclude that the hypothesis of a causal relationship between the gut microbiome and autism is unsupported by science. Key findings include inadequate sample sizes and flawed statistical methods in studies attempting to establish this link. The authors argue for a more rigorous approach to studying this topic.
A team of researchers led by Dr. Michele Ardolino is bridging scientific fields to unlock the mechanisms behind effective immune responses in cancer patients. They will study the interactions between the immune system, nervous system, and gut microbiome to design more personalized treatment strategies.
Scientists have discovered a method to induce the production of colanic acid, a compound found to promote longevity in animals, by exposing their gut microbiota to low doses of antibiotic cephaloridine. This approach shows promise for leveraging bacteria-targeting drugs to enhance lifespan.
Primary Biliary Cholangitis (PBC) is a chronic autoimmune liver disease characterized by immune-mediated destruction of small intrahepatic bile ducts. Recent studies have highlighted the significance of gut microbiota dysbiosis in PBC, with reduced diversity and imbalanced flora contributing to disease progression. The gut microbiome a...
Researchers identified 15 bacterial species linked to CAD, including strains of friendly bacteria that can turn harmful. The study suggests that microbes play a critical role in the development and progression of CAD through inflammation, metabolic imbalance, and other pathways.
A new study from Texas Biomedical Research Institute found that low-dose THC significantly reduced side effects and inflammation caused by HIV and antiretroviral therapy. The treatment also increased serotonin levels, lowered cholesterol and toxic bile acids, and improved cardiovascular health.
A recent study published in The FEBS Journal found that specific gut bacteria can efficiently metabolize different forms of nitrogen, preventing carcinogenic nitrosamine formation. This process is critical for maintaining intestinal and systemic health, potentially decreasing the risk of certain cancers.
A comprehensive review synthesizes current insights into the intricate connections between gut microbiota and sleep regulation, highlighting the crucial role of peripheral organs in modulating brain function and behavior. Disruptions in gut microbiota composition are closely linked to sleep disturbances across multiple disorders.
The microbiota is recognized as a dynamic organ producing molecules that regulate gene expression, immunity, and mitochondrial function. Biomarkers of inflammation, metabolism, and aging can be predicted through microbiota signatures, establishing the microbiota as a pillar of predictive medicine.
A new UCLA Health study found that a child's early gut microbiome may influence their risk of developing depression, anxiety or other internalizing symptoms in middle childhood. The effect appears to be related to the way bacteria are linked to communication across emotion-related brain networks.
A study from the Champalimaud Foundation found that when fruit flies are deprived of essential amino acids, their brains upregulate two olfactory receptor genes involved in smell, leading to a refined sense of smell that guides them to protein-rich yeast and gut bacteria. This interplay between smell and taste regulates feeding behavior.
A new study reveals that a specific E. coli strain can block the gut's defense mechanism by injecting a protein called NleL, allowing it to spread more easily. This discovery could lead to new treatments that target how bacteria cause disease.
A healthy microbiome promotes overall well-being, influencing areas like cognition, mood, immunity, and disease susceptibility. By incorporating proven dietary interventions, regular exercise, stress reduction, and adequate sleep, individuals can harness their microbiome for optimal health.
Research from the University of Gothenburg has identified two bacteria that can produce bioactive serotonin, a key player in bowel movements and brain function. These findings suggest new avenues for treating functional gastrointestinal disorders like IBS.
Researchers found that Candida albicans overgrowth increases inflammatory molecules PGE2, altering dopamine signaling and reducing desire for alcohol. Blocking PGE2 activity reverses the behavior, suggesting a potential link between gut microbiota and alcohol consumption.
Researchers discovered a mechanism by which certain bacteria can induce quiescence in cancer epithelial cells, making them resistant to chemotherapy. Understanding this microbe-tumor relationship may lead to the development of smarter therapies that can target treatment-resistant cancers.
Researchers discovered that non-hibernating pikas alter their gut microbiota to increase urea nitrogen salvaging, maintaining protein homeostasis during winter. This adaptation helps the animals cope with the scarcity of dietary protein during the cold season.
Researchers analyzed feces samples from 11 herbivore species in Namibia's Etosha National Park to understand how environmental factors shape their gut microbiomes. The study found five types of bacteria serving as environmental indicators, which could help monitor ecosystem changes and animal adaptation.
A new study links gut dysbiosis to severe steatosis in MASLD, improving diagnostic accuracy when microbiota status is added to standard clinical tools. The inflammation-linked Bact2 enterotype is strongly associated with severe hepatic steatosis in MASLD.
Dr. Amin's transformative insights reshape international understanding of depression genetics, identifying novel therapeutic targets and biomarkers for diagnosis and treatment. Her systemic disease model challenges traditional views of depression as a brain disorder.
Researchers found that hosts harboring different microbial strains exhibited neurobehavioral differences. The study identified 34 significant associations between microbial single nucleotide variations and host plasma metabolites, primarily related to key physiological processes such as neuroactive regulation and oxidative stress.
Researchers from the University of South Australia explore the connection between the gut and brain to decipher their role in mental health and wellbeing. The study found that changes in the gut microbiome can directly affect brain chemistry, suggesting a potential link between gut health and mental illness.
The 2-day conference focuses on bridging the fields of mitochondrial biology, microbiome research, and extracellular vesicle science to advance translational innovation. Experts will discuss EVs as core messengers in intercellular communication and their potential therapeutic applications.
The study reveals that Christensenella tenuis significantly reduces LPS levels and improves glucose and lipid metabolism in diet-induced obesity mice. It achieves this through a distinct bile acids-LPS interaction, preventing LPS from translocating into the bloodstream.
A year-long study on Japanese macaques found that their gut microbiome composition and fermentative ability adjust seasonally to improve digestive efficiency. The study reveals that mature leaf consumption boosts the fermentative ability of the gut microbiome, helping monkeys handle chemically defended foods during harsh winters.
This comprehensive metagenomic survey reveals vast gut microbiome diversity, with 21,902 species-level genome bins identified. The study also uncovers a significant reservoir of previously uncharacterized microbes and identifies high-risk antibiotic resistance genes across 14 mammal species.
Researchers identified a cellular mechanism that alters the gut microbiome in a way that promotes cancer. Long-chain fatty acids serve as food for certain bacteria, such as Desulfovibrio fairfieldensis, which multiply and displace other microbes.
The University of California - Riverside is receiving a $2 million grant to investigate how gut microbes interact with their human hosts to influence health. The research aims to create next-generation probiotics that strengthen the gut microbiome, improve vaccine effectiveness, and prevent infections.
Research links oral bacteria to Parkinson's disease via the gut-brain axis, finding Streptococcus mutans produces metabolite imidazole propionate that contributes to disease progression. Targeting the oral-gut microbiome may offer a new therapeutic approach for Parkinson's treatment.
Researchers developed an engineered strain of gut-homing bacteria that induces mature tertiary lymphoid structures, associated with improved survival and stronger treatment responses. The therapy also restored healthy gut microbiota and showed excellent biocompatibility.
A study in mice found that maternal consumption of emulsifiers can alter the gut microbiota of their offspring, leading to increased risk of chronic inflammatory gut disorders and obesity. The research highlights the importance of regulating food additives, particularly in powdered baby formulas, to prevent long-term health consequences.
Researchers at DTU have discovered a way to combat antibiotic-resistant bacteria by nourishing special bifidobacteria that is naturally occurring in the gut. Special lactic acids produced by bifidobacteria play a key role in keeping antibiotic-resistant bacteria at bay.
Researchers found genetic peptides called alpha-defensins that shape gut bacteria, producing healthier microbiomes and reducing insulin resistance. This discovery suggests personalized treatments can be tailored to individual genes, offering new hope for addressing chronic diseases like obesity and diabetes.
A study published in Cell Host & Microbe found a significant link between the maternal gut microbiome and preterm birth. The researchers identified Clostridium innocuum as a key bacteria species that may contribute to preterm birth by degrading estradiol, a critical hormone during pregnancy.