Articles tagged with Gut Microbiota
Research from RIKEN Center for Integrative Medical Sciences found that infant gut bacteria are associated with food sensitivities and allergies, particularly to eggs. The study suggests that probiotic supplements, such as Bifidobacterium, may help prevent food allergies in at-risk infants.
A new study reveals that a non-industrialized diet can significantly reduce the risk of chronic diseases such as obesity, diabetes, and heart disease. The diet, called NiMe TM, improved gut microbiome features damaged by industrialization, leading to beneficial changes in cardiometabolic markers.
A recent study from Purdue University reveals that adopting a consistent dietary pattern featuring lean red meat can contribute to gut microbiota balance and support cardiovascular health. The study found that maintaining a balanced diet with lean red meat is more effective in sustaining long-term health benefits.
A new study finds that excess RELMb protein in the intestine disrupts tolerance to triggering foods and increases the risk of food allergy. Inhibiting RELMb may lead to a cure or prevention of food allergy, offering a promising therapeutic approach.
Researchers found that a person's microbiome signature can predict the likelihood of Enterobacteriaceae colonization. Fiber-rich foods support the growth of beneficial Faecalibacterium, which produce short-chain fatty acids protecting against infection.
Scientists at HIRI have made significant progress through a series of in vitro and in vivo experiments, revealing a complex RNA-based regulatory circuit governing PUL expression in B. thetaiotaomicron.
A new study from Aarhus University Hospital shows that fecal microbiota transplantation can be a safe and effective treatment for patients with type 1 diabetes and gastroenteropathy. The treatment has significantly improved quality of life and symptoms for participants, offering hope to those with debilitating symptoms.
A new Tulane University study suggests that the Mediterranean diet's brain-boosting benefits may work by changing the balance of bacteria in the gut. Researchers found that subjects following a Mediterranean diet developed distinctly different gut bacteria patterns compared to those eating a typical Western diet.
A University of Toronto study discovered a new communication pathway between the gut and lung, highlighting the role of a little-known protozoan in shaping immune responses. The study found that this microbe can worsen airway inflammation in allergic asthma but provide protection against respiratory infections.
Researchers found a link between chronic gut infection with cytomegalovirus and the development of Alzheimer's disease, suggesting that the virus may contribute to immune system changes and brain inflammation. The study suggests that existing antiviral drugs could potentially treat or prevent this form of Alzheimer's.
A study by Michigan Medicine researchers suggests that sulfur-producing bacteria may be behind lingering Crohn's disease symptoms, even in the absence of inflammation. The study found that these bacteria can lead to increased visceral hypersensitivity and altered intestinal permeability, contributing to persistent symptoms.
Researchers discovered a set of genes in Lactiplantibacillus plantarum that enable it to stably attach to host tissue, revolutionizing our understanding of microbiome colonization. This breakthrough could lead to the creation of targeted probiotics and improved gut health.
A new study has linked the diversity of a wild bird's gut microbiome with its ornamentation and body condition. Researchers found that a cardinal's gut microbiome can be predicted by its body condition, and the quality of its ornamentation, such as red plumage and beak. This discovery has important applications for conservation biology.
Researchers used MRI to investigate how a gluten-free diet affects people with coeliac disease, finding improved gut symptoms but persistent issues. The study also identified changes in the gut microbiome, suggesting potential prebiotic treatments.
A new study has unveiled how stem cells respond to their environment, with implications for inflammatory bowel disease and colorectal cancer. Stem cells rely on PIEZO1 and PIEZO2 ion channels for survival, and loss of these channels leads to severe illness and rapid death.
A Northwestern University study found that gut microbes from large-brain primate species, such as humans and squirrel monkeys, can increase energy production in mice, while those from small-brain species like macaques store more energy as fat. This suggests a link between the microbiota and brain evolution.
Chronic cigarette exposure in mice leads to altered gut and oropharyngeal microbiota, aggravating flu severity. The study suggests that the smoker's microbiota plays a significant role in respiratory disease and viral infection.
A new study reveals dramatic changes to gut and mouth bacteria in people with chronic liver disease, correlating with increased antibiotic resistance and poor clinical outcomes. The findings suggest a need for personalized microbiome-based treatments and rapid diagnosis of infections to improve patient care.
Recent studies have demonstrated a causal role for the gut microbiome in multiple diseases, including gastrointestinal conditions and immune-related disorders. Manipulating the gut microbiome may open new avenues for treatment, such as fecal microbiota transplantation (FMT) showing efficacy in reducing CDI recurrence rates up to 93%.
The winners of the Applied Microbiology International Horizon Awards 2024 have been named, including the One Health Microbiome Center at Penn State and researchers Dr. François Thomas and Dr. Helen Onyeaka.
A longitudinal study found that bacteria associated with inflammation in the gut increases ten months before patients develop clinical rheumatoid arthritis. Researchers are exploring potential treatments at this early stage to prevent disease progression.
A new study found that gut bacteria may promote healthy aging by replacing declining gut bacteria species with alternative substrates. Researchers identified key microbial species associated with aging and their potential effects on health.
A new perspective paper emphasizes the critical role of diet in shaping the efficacy of prebiotics and probiotics. The authors found that diet significantly affects gut microbiome composition and function, potentially impacting the success of these interventions. Researchers are urged to collect data on participants' background diets a...
A study reveals that infant gut microbiota succession is predictable and malleable, allowing for the shaping of gut health through birth mode and feeding practices. This research has significant implications for reducing childhood allergic diseases, overweight, and respiratory infections.
A new study found compositional and functional differences in the gut microbiota of Chinese long-living adults (over 90 years) compared to elderly adults (65–74 years). The researchers noted lower relative abundances of bacteria in certain genera, which may regulate biological processes like autophagy and telomere maintenance. These fi...
Researchers identify two distinct groups of bacteria: the Foundation Guild and Pathobiont Guild, crucial for maintaining human health. The Two Competing Guilds model offers personalized nutrition and targeted therapies to restore balance in the gut microbiome.
A new study reveals how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer. The research identified a particular bacterial species as a potential therapeutic target, specifically Lactobacillus genus, which is essential for a healthy immune response against cancer.
Researchers at TUM found that mitochondrial dysfunction in mice leads to chronic intestinal inflammation and changes in the gut microbiome. The study suggests potential new treatments targeting mitochondrial pathways or addressing the connections between the microbiome and mitochondria.
A Baylor University researcher has earned a transformative research award to develop personalized treatments for gut microbiome diseases. The project aims to identify specific bacteria that perform restorative activities and develop targeted fecal microbiota transplantations tailored to individual needs.
A new study reveals that fecal microbiota transplants can increase Lachnospiraceae bacteria, which outcompete C. diff for resources and alter bile acids to create an environment favorable for other good bacteria to thrive.
A new framework outlines essential criteria for establishing prebiotic status, emphasizing selective utilization, measurable health benefits, and safe use. The proposed guidelines aim to promote clarity and informed decision-making around prebiotic products.
A study found that doxycycline post-exposure prophylaxis (doxy-PEP) did not significantly alter the overall composition of gut bacteria in individuals who took it for six months. However, the researchers noted signs of resistance building against tetracycline, a class of antibiotics to which doxycycline belongs.
Scientists have created carbon dot nanozymes that reduced oxidative stress, rebalanced gut microbes and alleviated stress-induced depression in rats. The treatment restored the balance of microbes, which can trigger inflammation and alter brain function, highlighting the link between gut health and mental health.
A new study found that antibiotic use in aged care leads to antibiotic-resistant bacteria in the gut, posing a significant risk to vulnerable residents. Researchers analysed stool samples from 164 residents and discovered nearly all carried resistant genes without symptoms.
A randomized clinical trial found camu-camu extract reduced liver lipids by 7.43%, while a placebo increased them by 8.42%. The effect is attributed to polyphenols and their relationship with intestinal microbiota.
Researchers have discovered a new site on beta-2 adrenergic receptors that allows healthy signals to pass through, minimizing harmful side effects of beta-blocker medication. The gut microbial pathway is associated with cardiovascular disease risks and can be independently targeted.
Researchers at UBC have identified a specific cascade of events that lead to allergies and asthma after early-life antibiotic use. The study found that butyrate-producing bacteria play a key role in halting the allergic response, and that targeting ILC2 cells may provide new treatment options.
Researchers discuss the role of gut microbiota in regulating basal inflammation levels and promoting healing of the bowel after surgery. Weakened gut barrier function may lead to persistent low-grade inflammation and increased risk of cancer recurrence.
A new study by Ohio State University Wexner Medical Center found that probiotics can improve the immune system and behavior of both mothers and their offspring during pregnancy. Probiotics may also help counteract negative effects of prenatal stress, such as changes in brain inflammation and amino acid metabolism.
A new Cleveland Clinic study reveals that diet-derived molecules called metabolites are the main drivers of young-onset colorectal cancer risk, particularly those associated with red and processed meat. The research suggests that addressing diet with doctors can help prevent colon cancer in younger adults.
A recent study found that C-section antibiotics have a subtle impact on the infant gut microbiome, whereas diet has a significant impact. The study analyzed data from 172 infant samples and found that feeding mode explained 12% of variation in overall infant gut microbiome composition.
A new study from the University of Surrey found that higher faecal bacterial diversity at one month old is positively associated with the athletic performance of Thoroughbred foals. Lower bacterial diversity in early life also increases the risk of respiratory disease and soft-tissue issues.
A new study published in Cell Reports Medicine found that a ketogenic diet can reduce beneficial gut bacteria and increase unfavorable fats in the blood. The diet, which is high in fat and low in carbohydrates, may have long-term health implications such as increased risk of heart disease and stroke.
A randomized crossover clinical trial reveals that swapping refined corn flour for a blend of refined corn flour and corn bran lowers LDL cholesterol concentrations by 5-13.3%. The study found significant reductions in LDL cholesterol among 70% of participants who consumed the blend, while whole-grain corn meal had no impact.
Researchers found that Megamonas degrades intestinal myo-inositol, enhances lipid absorption, and contributes to obesity. The study suggests potential strategies for future obesity management by illustrating the bacterium's mechanism.
A study identified a protein called IL-22BP that affects the composition of gut microbiota and the body's response to bacterial infection. The absence of this protein results in stronger defenses against intestinal infections, including increased production of short-chain fatty acids that promote an anti-inflammatory environment.
A clinical trial found that fecal microbiota transplants can boost the effectiveness of immunotherapy in a range of gastrointestinal cancers. The study identified specific bacterial strains associated with better or worse responses, and showed promise for improving treatment outcomes.
A new study found that high doses of red seaweed reduce methane emissions in cows, but the effect is short-lived. The researchers discovered that the seaweed inhibits methanogenic microbes, leading to a near-total elimination of a key microbe involved in methane formation.
Researchers analyzed fecal samples from fat cats undergoing different dietary changes and found striking similarities to human studies, particularly in the presence of short-chain fatty acids. The study suggests that feline gut microbiome shifts may correlate with metabolic outcomes and provide valuable insights for obesity treatment.
Researchers found that bowel movement frequency is linked to long-term health, with younger people, women, and those with lower BMI tending to have less frequent bowel movements. The study also showed associations between bowel movement frequency and chronic disease risk, mental health history, and gut microbiome composition.
Research found that unhealthy gut microbiome patterns are associated with a heightened risk of death after solid organ transplant. The analysis revealed that the more the gut microbiome patterns diverge from those of the general population, the more likely they are to die sooner after their procedure. High numbers of certain bacterial ...
Researchers found that a live biotherapeutic product CBM588, when taken orally, can improve health outcomes in people with metastatic kidney cancer. The study, published in Nature Medicine, suggests that the agent may enhance effectiveness of FDA-approved cancer immunotherapies by adjusting the gut microbiome.
Research by a University of Virginia undergraduate may help explain recurrent Crohn’s disease in children and open the door to new ways to treat or even cure the devastating condition. Children with relapsing Crohn’s had persistent disruptions of their microbiomes even after inflammation was successfully controlled.
Researchers have identified Stomoxys flies as carriers of pathogenic bacteria that cause bovine mastitis. The study found that these bacteria are more abundant in the fly gut than in manure samples, suggesting a link between insect bites and disease transmission.
A new Cornell University study found that dietary fiber recommendations should be tailored to each person's unique gut microbiome. The research identified two types of resistant starch and found that individuals may respond differently to these foods, with some benefiting from increased fiber intake and others experiencing no effect.
Researchers developed a novel approach to simulate personalized, microbiome-mediated responses to diet using microbial community-scale metabolic modeling. The method predicts individual-specific short-chain fatty acid (SCFA) production rates in response to different dietary, prebiotic, and probiotic inputs.
A new UCLA Health study found that resilient individuals have neural activity in brain regions associated with emotional regulation and better cognition. They also exhibited a healthy gut microbiome with reduced inflammation and improved gut barrier function.
Researchers found a link between gut microbiota and Parkinson's disease, revealing reduced B vitamins and intestinal barrier issues. Treatment with B vitamins could alleviate PD symptoms and slow disease progression.
Researchers found that nasal microbiota of ICU patients with sepsis is significantly lower in community richness and has distinct compositions compared to non-septic patients. Key bacterial genera such as Corynebacterium, Staphylococcus, Acinetobacter, and Pseudomonas were enriched in the nasal microbiota of septic patients.
Researchers found that many bacterial strains present in infants at 3 weeks, months, and 12 months originated from the father, not the mother. This discovery highlights the importance of physical and social interactions between newborns and their fathers, as well as with other family members.