Articles tagged with Gut Microbiota
The international conference will focus on translating phage research into clinical reality, exploring key sessions and major speakers. Companies from various sectors are attending the event, highlighting the growing interest in phage therapy.
A study published in Cell Metabolism finds that a combination of gut bacteria and acetate reduces obesity in mice. The researchers discovered that the specific combination of Bacteroides species and acetate leads to increased fat burning and reduced sugar storage, resulting in weight loss.
A Brazilian study of over 700 infants found that ultra-processed food consumption negatively affects gut diversity and abundance, particularly in non-breastfed children. Breastfeeding mitigates this effect, promoting higher Bifidobacterium levels and better health markers.
Researchers have shown that good gut bacteria can manipulate the immune system's response, leading to rheumatoid arthritis. The study found that T cells in the gut can transform into super-powerful and potent cells that attack the body's tissues.
A study by Swansea University reveals that native and invasive small mammals are sharing their gut microbes as habitats change, highlighting the importance of microbiome similarity in adaptation to new environments. This finding has implications for understanding the impact of urbanization on wildlife health and disease spread.
A new study by Virginia Tech researchers suggests that bacteriophages, or virus-like particles, may increase the sensitivity of gut bacteria to antibiotics. The team created a mouse model that allows them to control phage populations and found evidence that phages can exacerbate antibiotic damage.
A new review from Marshall University researchers highlights emerging connections between gut health and sleep apnea, pointing to potential new therapeutic approaches for managing this common disorder. Alterations in gut microbiota composition have been consistently observed in individuals with sleep apnea, inducing systemic inflammati...
The study found that fecal microbiota transplantation (FMT) can outcompete H. pylori, producing antimicrobial peptides and metabolic byproducts to create a hostile environment. FMT may also mitigate adverse effects of antibiotic treatments, improving patient tolerance.
A study in the journal Cell Host & Microbe found that a diet rich in soluble fiber can protect against pathogenic bacteria like Clostridioides difficile. Consuming soluble fiber produces compounds like acetate, which regulates immune response and reduces inflammation.
The 8th World Congress on Targeting Phage Therapy 2025 will bring together global phage community to address clinical, regulatory, and industrial challenges. The event will feature cutting-edge research, real-world clinical insights, and applications of bacteriophage therapy across medicine, oncology, agriculture, and industry.
A cross-disciplinary research team from HKU has found a connection between oral microbiota and ASD, identifying 11 bacterial species as potential biomarkers. The study developed a prediction model with an 81% accuracy rate for early detection, paving the way for non-invasive screening tools during dental check-ups.
A new study from Cedars-Sinai examined the effectiveness of a specialized diet in improving symptoms of gastrointestinal disorders linked to an imbalance in gut microbiota. The research found that most participants reported tolerating the diet well and experienced significant relief from common symptoms like bloating and discomfort.
A study published in Cell suggests that the gut microbiome can play a key role in protecting against gastrointestinal (GI) diseases by breaking down certain plant compounds. The researchers found that specific intestinal microbes release beneficial small molecules that regulate inflammation and promote resistance to pathogens, such as ...
Research reveals the gut microbiota-metabolite-brain axis plays a critical role in Sevoflurane-induced neurotoxicity, particularly in neonatal mice. The study demonstrates that fecal microbiota transplantation and bile acid regulation can rescue social behavior deficits and improve synaptic function.
Researchers found that changes in gut bacteria after a stroke lead to an increase in harmful substances and a decrease in beneficial ones, potentially causing inflammation. Restoring these beneficial substances from gut bacteria could help reduce inflammation after a stroke.
Researchers developed a transformation process to boost H₂Sₙ yield from garlic-derived compounds, achieving significant H. pylori eradication outcomes. The use of chitosan-encapsulated microreactors demonstrated enhanced efficacy and faster eradication rates compared to conventional methods.
Research suggests flavonoids improve insulin sensitivity, enhance β-cell function, modulate the gut microbiota, inhibit gluconeogenesis, and regulate enteroendocrine hormones in type 2 diabetes management. Flavonoid-specific effects on GLP-1, GIP, PYY, and CCK secretion contribute to improved glycemic control.
The summit will highlight the latest research on coronavirus, plant-based protein, and probiotics, with a focus on their applications in clinical practice. Studies have found that COVID-19 affects the gut microbiome in children, while dietary protein like S100B may promote a healthy microbiome.
A study has established the importance of immunoglobulin A in generating a response to pneumonia vaccines. The research found that poor regulation of gut microbiota can lead to an inadequate immune response, leaving individuals vulnerable to respiratory infections.
Researchers investigated the effects of electroacupuncture on gut microbiota and metabolomics in ALS patients, finding a reduction in Eisenbergiella abundance and improvements in Lachnospiraceae levels. The study suggests that this treatment may be beneficial for patients with ALS.
Research in mice found that early-life gut microbes shape insulin-producing cell development and reduce long-term changes in metabolism and diabetes risk. Exposure to a fungus called Candida dubliniensis during infancy may also promote lifelong metabolic health by supporting the growth of insulin-producing cells.
The Blavatnik Awards for Young Scientists in the UK recognize promising scientists under 42 for their work on pressing issues. The three winners are tackling infant mortality, green manufacturing, and predicting long-term climate change. Their prize-winning research will receive £100,000 in unrestricted funds.
Researchers from the University of Toronto have shown that a low-carb diet can worsen the DNA-damaging effects of certain gut microbes, increasing the risk of colorectal cancer. A unique strain of E. coli bacteria was found to drive polyp growth in the colon when paired with a low-carb diet.
Researchers developed a synthetic microbiome therapy using limited strains of gut bacteria to effectively protect against C. difficile infections in mice. The treatment was as effective as traditional fecal transplants and had fewer safety concerns, offering a new alternative for treating this notoriously difficult-to-treat infection.
Researchers have discovered that giraffes maintain species-specific gut flora, even when eating different sets of plants. This finding has significant implications for the conservation of endangered giraffe species, highlighting the importance of understanding their diets and habitats to ensure their survival.
A Dartmouth-led study reveals that cystic fibrosis disrupts the maturation of the gut microbiome in infants, leading to a depletion of health-associated bacteria and potentially poor health outcomes. The study found that the microbiomes of infants with CF remained stunted or delayed in their development compared to healthy infants.
Researchers found a clear causal relationship between gut microbiota and vagal nerve activity in mice. Introducing gut bacteria restored vagal activity, while antibiotics had no impact on germ-free mice. The study identified specific metabolites produced by the gut microbiome that activate the vagus nerve.
Researchers at TUM have developed a new therapeutic approach combining dietary therapy with fecal microbiome transfer to sustain inflammation-free states in Crohn's disease patients. The study found that the gut microbiome changes as a result of dietary therapy contribute to treatment success.
A new Weizmann Institute study identified all proteins in a stool sample – those from the microbiome, human body, and food – revealing secrets of the intestines and their impact on human disease. The method, dubbed IPHOMED, decodes microbiome activity by showing which proteins come from bacterial strains and amounts.
Researchers identified a potential mechanism linking sugary beverage consumption to diabetes risk through alterations in the gut microbiome and blood metabolites. High sugar-sweetened beverage intake was associated with changes in bacterial species that produce short-chain fatty acids, negatively impacting glucose metabolism.
Research from RIKEN Center for Integrative Medical Sciences found that infant gut bacteria are associated with food sensitivities and allergies, particularly to eggs. The study suggests that probiotic supplements, such as Bifidobacterium, may help prevent food allergies in at-risk infants.
A new study reveals that a non-industrialized diet can significantly reduce the risk of chronic diseases such as obesity, diabetes, and heart disease. The diet, called NiMe TM, improved gut microbiome features damaged by industrialization, leading to beneficial changes in cardiometabolic markers.
A recent study from Purdue University reveals that adopting a consistent dietary pattern featuring lean red meat can contribute to gut microbiota balance and support cardiovascular health. The study found that maintaining a balanced diet with lean red meat is more effective in sustaining long-term health benefits.
A new study finds that excess RELMb protein in the intestine disrupts tolerance to triggering foods and increases the risk of food allergy. Inhibiting RELMb may lead to a cure or prevention of food allergy, offering a promising therapeutic approach.
Researchers found that a person's microbiome signature can predict the likelihood of Enterobacteriaceae colonization. Fiber-rich foods support the growth of beneficial Faecalibacterium, which produce short-chain fatty acids protecting against infection.
Scientists at HIRI have made significant progress through a series of in vitro and in vivo experiments, revealing a complex RNA-based regulatory circuit governing PUL expression in B. thetaiotaomicron.
A new study from Aarhus University Hospital shows that fecal microbiota transplantation can be a safe and effective treatment for patients with type 1 diabetes and gastroenteropathy. The treatment has significantly improved quality of life and symptoms for participants, offering hope to those with debilitating symptoms.
A new Tulane University study suggests that the Mediterranean diet's brain-boosting benefits may work by changing the balance of bacteria in the gut. Researchers found that subjects following a Mediterranean diet developed distinctly different gut bacteria patterns compared to those eating a typical Western diet.
A study by Michigan Medicine researchers suggests that sulfur-producing bacteria may be behind lingering Crohn's disease symptoms, even in the absence of inflammation. The study found that these bacteria can lead to increased visceral hypersensitivity and altered intestinal permeability, contributing to persistent symptoms.
A University of Toronto study discovered a new communication pathway between the gut and lung, highlighting the role of a little-known protozoan in shaping immune responses. The study found that this microbe can worsen airway inflammation in allergic asthma but provide protection against respiratory infections.
Researchers found a link between chronic gut infection with cytomegalovirus and the development of Alzheimer's disease, suggesting that the virus may contribute to immune system changes and brain inflammation. The study suggests that existing antiviral drugs could potentially treat or prevent this form of Alzheimer's.
Researchers discovered a set of genes in Lactiplantibacillus plantarum that enable it to stably attach to host tissue, revolutionizing our understanding of microbiome colonization. This breakthrough could lead to the creation of targeted probiotics and improved gut health.
A new study has linked the diversity of a wild bird's gut microbiome with its ornamentation and body condition. Researchers found that a cardinal's gut microbiome can be predicted by its body condition, and the quality of its ornamentation, such as red plumage and beak. This discovery has important applications for conservation biology.
Researchers used MRI to investigate how a gluten-free diet affects people with coeliac disease, finding improved gut symptoms but persistent issues. The study also identified changes in the gut microbiome, suggesting potential prebiotic treatments.
A Northwestern University study found that gut microbes from large-brain primate species, such as humans and squirrel monkeys, can increase energy production in mice, while those from small-brain species like macaques store more energy as fat. This suggests a link between the microbiota and brain evolution.
A new study has unveiled how stem cells respond to their environment, with implications for inflammatory bowel disease and colorectal cancer. Stem cells rely on PIEZO1 and PIEZO2 ion channels for survival, and loss of these channels leads to severe illness and rapid death.
Chronic cigarette exposure in mice leads to altered gut and oropharyngeal microbiota, aggravating flu severity. The study suggests that the smoker's microbiota plays a significant role in respiratory disease and viral infection.
A new study reveals dramatic changes to gut and mouth bacteria in people with chronic liver disease, correlating with increased antibiotic resistance and poor clinical outcomes. The findings suggest a need for personalized microbiome-based treatments and rapid diagnosis of infections to improve patient care.
Recent studies have demonstrated a causal role for the gut microbiome in multiple diseases, including gastrointestinal conditions and immune-related disorders. Manipulating the gut microbiome may open new avenues for treatment, such as fecal microbiota transplantation (FMT) showing efficacy in reducing CDI recurrence rates up to 93%.
The winners of the Applied Microbiology International Horizon Awards 2024 have been named, including the One Health Microbiome Center at Penn State and researchers Dr. François Thomas and Dr. Helen Onyeaka.
A longitudinal study found that bacteria associated with inflammation in the gut increases ten months before patients develop clinical rheumatoid arthritis. Researchers are exploring potential treatments at this early stage to prevent disease progression.
A new study found that gut bacteria may promote healthy aging by replacing declining gut bacteria species with alternative substrates. Researchers identified key microbial species associated with aging and their potential effects on health.
A new perspective paper emphasizes the critical role of diet in shaping the efficacy of prebiotics and probiotics. The authors found that diet significantly affects gut microbiome composition and function, potentially impacting the success of these interventions. Researchers are urged to collect data on participants' background diets a...
A study reveals that infant gut microbiota succession is predictable and malleable, allowing for the shaping of gut health through birth mode and feeding practices. This research has significant implications for reducing childhood allergic diseases, overweight, and respiratory infections.
A new study found compositional and functional differences in the gut microbiota of Chinese long-living adults (over 90 years) compared to elderly adults (65–74 years). The researchers noted lower relative abundances of bacteria in certain genera, which may regulate biological processes like autophagy and telomere maintenance. These fi...
Researchers identify two distinct groups of bacteria: the Foundation Guild and Pathobiont Guild, crucial for maintaining human health. The Two Competing Guilds model offers personalized nutrition and targeted therapies to restore balance in the gut microbiome.
A new study reveals how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer. The research identified a particular bacterial species as a potential therapeutic target, specifically Lactobacillus genus, which is essential for a healthy immune response against cancer.
Researchers at TUM found that mitochondrial dysfunction in mice leads to chronic intestinal inflammation and changes in the gut microbiome. The study suggests potential new treatments targeting mitochondrial pathways or addressing the connections between the microbiome and mitochondria.
A Baylor University researcher has earned a transformative research award to develop personalized treatments for gut microbiome diseases. The project aims to identify specific bacteria that perform restorative activities and develop targeted fecal microbiota transplantations tailored to individual needs.
A new study reveals that fecal microbiota transplants can increase Lachnospiraceae bacteria, which outcompete C. diff for resources and alter bile acids to create an environment favorable for other good bacteria to thrive.