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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Microbes scared to death by virus presence

Recent study reveals that microbes like Sulfolobus islandicus can freeze in place when infected with a harmless virus, such as Sulfolobus spindle-shaped virus 9 (SSV9), to protect themselves. The dormant microbes recover if the virus is removed within 24-48 hours, otherwise they die.

Deadly to cancer cells only

Researchers discovered a molecular cause for parvovirus selectivity in cancer cells, revealing the PKCη/Rdx-driven phosphorylation of PDK1. This biomarker predicts therapy effectiveness and identifies cancer cells independent of growth factors.

New study reveals widespread risk of infectious diseases to wild bees

Researchers have discovered a network of viruses that pose a threat to multiple species of bumblebees and managed honeybees, highlighting the urgent need for disease management strategies. The study found five viruses, including deformed wing virus, in wild bees across Great Britain.

New approach to tackle alphavirus infections

A new approach to tackling alphavirus infections has been developed using the protein pentraxin 3, which plays a crucial role in promoting virus infection and disease. This breakthrough discovery paves the way for improved vaccine and drug development.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Lighting up a new path for novel synthetic polio vaccine

Researchers are creating a synthetic vaccine that mimics the structure of the live virus to provide a quicker, easier, and safer alternative. The goal is to eradicate polio without the danger of accidental release associated with traditional vaccines.

New protein detonates 'invincible' bacteria from within

Researchers at Tel Aviv University identified a novel protein capable of targeting and inhibiting the activity of a protein essential to bacterial cells. This discovery may strengthen efforts to combat antibiotic-resistant infections and presents a potential breakthrough in the fight against superbugs.

Tightly packed in its shell

Researchers found that even minimal mutations in viral RNA can make it too bulky for the capsid, preventing replication. The study used computer simulations and verified previous research on optimized RNA packing.

Stay complex, my friends

Researchers found that long-lasting hosts evolved more complex defenses against parasites, providing a survival advantage. The study used the Avida platform to model co-evolution between host and virus, revealing a surprising large proportion of 'switching' mutations in co-evolved hosts.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Response to viral infections depends on the entry route of the virus

Researchers found that immune mechanisms triggered by viruses differ depending on entry route, with Toll pathway activated for feeding-related infections. The study suggests that understanding these differences can help find targets to block human diseases transmitted by insects.

Some flu viruses potentially more dangerous than others

A study found that flu viruses expressing specific avian hemagglutinins led to fatal infections in mice and caused significant cell damage in human lung cells. These findings suggest that certain hemagglutinins may induce programmed cell death, leading to enhanced disease severity.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Self-repairing software tackles malware

Researchers have developed a self-repairing software called A3 that detects and eradicates malware, repairing damage and preventing re-infection. The software can repair complex security vulnerabilities in minutes without taking servers down.

Viral switches share a shape

Researchers have discovered that multiple viruses share an L-shaped switch in their RNA genomes, which can be flipped to prevent replication. The discovery has implications for developing new drugs to inhibit viral replication, particularly for hepatitis C virus.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

New research decodes virus-host interactions in ocean dead zones

A new study reveals that marine viruses are more important to microbial ecology below sunlit surface waters than previously suspected. The research focused on a sulfur-oxidizing bacterium called SUP05, which is dominant in oxygen minimum zones and has not been successfully cultivated in a lab setting.

61 percent fall in female genital warts due to free HPV vaccine

A study from the University of Sydney reveals a 61% decrease in genital wart management among young women since the introduction of the free HPV vaccination program. The vaccine has been effective in reducing genital warts and their treatment costs, with no significant change in other sexually transmitted infections.

Plug n' play protein crystals

Scientists from Aalto University create ordered structures by mixing oppositely charged proteins and virus particles, enabling modular functionalization with various ligands. The method opens possibilities for biomedical and materials science research.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Of bees, mites, and viruses

Researchers found that Deformed Wing Virus (DWV) is the most affected virus species by Varroa infestation, while Kashmir Bee Virus (KBV) peaks two years after initial infestation and disappears. The study highlights the importance of beekeeper awareness, mite monitoring, and efficient Varroa control.

Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Short circuit in the food web

Researchers discovered how viruses affect phytoplankton, like Emiliania huxleyi, altering global carbon cycle and marine food chain. Viruses rewire host lipid metabolism, diverting fixed carbon from traditional food web, with implications for ocean ecosystems.

Platonic solids generate their 4-dimensional analogues

Alicia Boole Stott and Ludwig Schlaefli showed that six platonic solids have four-dimensional counterparts, featuring strange symmetries. The spinorial construction explains these symmetries, shedding new light on both three- and four-dimensional geometries.

CU researchers explain mechanism that helps viruses spread

Researchers at the University of Colorado School of Medicine have solved a biochemical mystery surrounding viral RNA molecules. The study reveals how these molecules mimic cellular RNAs as part of their strategy to infect cells and multiply, offering insights into potential treatments or vaccines against infectious diseases.

Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Relaxation helps pack DNA into a virus

Researchers discovered that DNA relaxes to pack into virus heads at speeds determined by physics. The process counteracts the molecule's tendency to repel itself due to its negative charge.

Viruses hijack deep-sea bacteria at hydrothermal vents

Researchers found viruses force bacteria to burn sulfur reserves, releasing energy for viral replication. The study reveals a new microbial interaction in deep-sea environments, hinting that viruses act as agents of evolution in chemosynthetic systems.

Viral infections: Identifying the tell-tale patterns

Researchers at Ludwig-Maximilians-Universität München have identified the structural features that enable the innate immune system to distinguish viral from host RNAs. The RIG-I like receptors (RLRs) recognize specific patterns in viral RNAs, which differ from endogenous cellular RNAs.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

How the body fights against viruses

The human immune system uses enzymes like ADAR1 to modify viral genetic information, rendering it useless for new virus particles. The study reveals how the cell protects itself from accidental import of viral RNA into the nucleus.

The taming of the shrew

Researchers have discovered that the bicolored shrew acts as a 'pathogen reservoir' for the Borna virus, transmitting it to horses. The virus is not directly contagious and requires an intermediate host to spread, highlighting the importance of keeping shrews away from stables to prevent transmission.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Nano-paper filter removes viruses

Researchers at Uppsala University have developed a paper filter that can remove virus particles with efficiency matching the best industrial filters. The filter uses 100% high purity cellulose nanofibers directly derived from nature, overcoming previous limitations in virus removal.

New research seeks beneficial qualities of viruses

A multi-institutional team, led by Rachel Whitaker, studies host-viral interactions to understand how viruses can protect hosts from competitors and aid in survival. The research aims to develop a theoretical model of eco-evolutionary dynamics between viruses and microbes.

Now in 3-D: Video of virus-sized particle trying to enter cell

Scientists at Princeton University have created a 3D video of a virus-like particle attempting to enter a cell, revealing unprecedented details about the interaction. The technique developed could help deliver drugs via nanoparticles and prevent viral infections.

Predatory organisms at depth

In deep, old, and nutrient-poor marine sediments, viruses outnumber microbes by up to 225 times, controlling the size and composition of microbial communities. Viruses produce new viruses that remain in sediment for longer periods due to limited enzymatic destruction, leading to a high turnover rate.

Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Viral puzzles

Researchers identified weak points in capsids and inferred spontaneous assembly processes, discovering each shell is made of protein 'tiles' that spontaneously join up like Lego pieces.

Crop-infecting virus forces aphids to spread disease

Researchers at the University of Cambridge discovered that crop-infecting viruses use aphids as pawns to spread infection to healthy vegetation. By altering plant biochemistry, these viruses repel visiting aphids and force them to move to healthier plants, unwittingly transporting and spreading the virus.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Scientists discover why newborns get sick so often

New research reveals that newborns are born without the toll-like receptor 3, a key protein needed to protect against viruses. This impairment makes newborn immune cells unable to recognize and react to certain viruses, increasing their susceptibility to infections like herpes simplex virus.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Food additive may prevent spread of deadly new avian flu

Researchers at the University of Illinois Chicago have discovered a common food additive that can block a deadly new strain of avian influenza virus from infecting healthy cells. The compound, tert-butyl hydroquinone, targets a previously untapped region of the flu virus called hemagglutinin.

Drug activates virus against cancer

Researchers have found a synergistic combination of valproic acid and oncolytic parvovirus H-1PV that can effectively treat cervical and pancreatic carcinomas by activating virus-induced cell death and killing cancer cells. This new therapy has the potential to arrest tumor growth in severe cases of cancer.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

How a ubiquitous herpesvirus sometimes leads to cancer

Researchers discovered distinct EBV subtypes with varying public health risks, including a strain associated with nasopharyngeal carcinoma. This finding highlights the importance of tailoring prevention efforts to specific viral strains.

Making the most of what you have

The study reveals that the nonstructural protein 3 (NS3) protease of classical swine fever virus is capable of self-cleavage, generating two smaller proteins with distinct activities. This discovery sheds light on the complex regulation of viral replication and has significant implications for understanding persistent infections.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Viruses associated with coral epidemic of 'white plague'

Researchers at Oregon State University have identified a group of viruses associated with the coral epidemic 'white plague,' which has killed 70-80% of some reefs. The study suggests that viral diversity is higher in diseased corals, highlighting the need for further research to prevent this disease.

New technology transforms research in viral biology

Researchers developed a new system to test how viruses interact with cells in the body, revealing insights that will improve viral therapy. The technology allows for the use of real viruses in real environments, enabling scientists to study host targets for antiviral drugs.

Shingles symptoms may be caused by neuronal short circuit

Scientists at Princeton University discovered that herpes viruses may cause repetitive nerve cell firing, leading to persistent itching and pain. Understanding this mechanism could lead to improved treatments for shingles, oral, and genital herpes.

Malware bites and how to stop it

Researchers have developed a new approach to virus detection that uses data mining algorithms and machine learning techniques to identify malicious code and behavior patterns.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Rice writes rules for gene-therapy vectors

Researchers at Rice University have made strides toward creating a set of rules to design custom viral capsid proteins for gene therapy. By combining pieces of different adeno-associated viruses, they can create new, benign viruses that deliver DNA payloads to specific cells. This research has the potential to treat diseases such as ge...