Articles tagged with Viruses
A new study found that nonhuman primates in Bangladesh and Cambodia harbor diverse astroviruses, including human astroviruses, challenging the paradigm that AstV infection is species-specific. The researchers also detected recombinant viruses that may be more efficiently transmitted.
Researchers have discovered a new virus, Parramatta River virus, carried by saltmarsh Aedes vigilax mosquitoes, which do not pose direct health risks to humans. The discovery may lead to stopping outbreaks of mosquito-borne diseases by preventing the spread of 'bad' viruses.
The University of Pittsburgh Center for Vaccine Research has received a $7.6 million grant from the U.S. Department of Defense to accelerate development of drugs and vaccines against alphaviruses, deadly viruses transmitted by mosquitoes. The team aims to develop therapies and protection against these diseases.
New study reveals that histone deacetylase 6 inhibition improves the ability of oncolytic herpes simplex virus type 1 to kill glioma cells. HDAC inhibitors increase viral trafficking to the nucleus, leading to increased replication and tumor cell death.
Researchers have developed a high-speed electron tomography technique that sets new standards for 3D imaging of the nanoworld. The method enables visualization of dynamic processes and structures with sub-nanometre precision, opening up new horizons in life sciences and soft matter research.
Researchers discovered that flu viruses gain ability to spread through air by adapting to bind to specific human receptors, with the soft palate playing a key role in this process. The findings provide insight into how flu viruses evolve airborne transmissibility and can help identify viruses with potential to cause global outbreaks.
Researchers mapped antigenic differences in dengue virus strains, finding overlap among previously thought distinct groups. The findings suggest a continuum rather than separate groups, making vaccine development harder.
Researchers found significant antigenic difference within each dengue serotype, suggesting individuals infected with one type may not be protected against different strains. The study's findings have implications for vaccine design and understanding of the virus's evolution.
A new study found that viruses flourish in the guts of healthy infants, with diverse viral strains and a dynamic ecosystem of interacting organisms. The researchers discovered viral strains that exclusively kill bacteria, which declines as the babies grow older.
Researchers at the University of Wisconsin-Madison have developed a new method for making flu vaccines using cell culture, which could lead to faster and more efficient vaccine production. This technology could potentially replace traditional egg-based vaccine production methods, which are limited by avian influenza outbreaks.
Florida State University researchers have identified a viral protein that inhibits the major DNA sensor, suggesting a new pathway for fighting infections, cancer, and autoimmune diseases. By manipulating this protein, scientists may be able to enhance or tune down the immune response.
Researchers studied bats and rodents to identify characteristics of cross-species virus transmission. They found that viruses pass more easily between bat species than rodent species, with unique bat traits like gregariousness facilitating transmission.
Researchers develop VirSorter to identify previously unknown microbial hosts and analyze viral-host interactions, revealing a wide range of prophage-like viruses that coexist with their host microbes.
Harvard researchers have reconstructed an ancient virus effective at delivering gene therapies to liver, muscle, and retina. The discovery may lead to novel vectors for safer and more potent gene therapies.
A new diagnostic test has been developed to quickly detect enterovirus D68, a respiratory virus that caused unusually severe illness in children last year. The test is more effective than previous methods and can be completed in just a few hours, reducing the time needed to detect the virus.
Researchers discovered a human antibody specific to dengue virus serotype 2 that protects mice from the virus, regardless of administration timing. The antibody may act as both a preventative and therapeutic agent by locking viral envelope proteins on the surface, preventing them from entering host cells.
Singapore researchers have identified specific molecular interactions in the dengue virus genome that allow it to manipulate human immune defenses and spread more efficiently. These genetic changes increase the virus's capacity for epidemic outbreaks, highlighting the need for targeted surveillance and response strategies.
Researchers at UMN identified two key mutations in MERS virus enabling its transmission from bats to humans. These mutations allowed the virus to infect human cells, highlighting a crucial evolutionary strategy used by the virus.
Researchers developed a new technology called VirScan to identify all viruses an individual has been exposed to over their life. The study found that people are exposed to around 10 viral species on average, but some individuals encountered up to 84 different viral species.
Researchers have developed VirScan, a method that can analyze a single drop of blood to identify past and present viral infections. The technology shows promise in uncovering unexpected factors affecting individual patients' health and expanding opportunities for large-scale analysis.
Researchers at ETH Zurich developed a new multiplexing technique that accelerates nanoMRI imaging, enabling faster and more efficient scanning of nanoscale objects. The technique cuts normal scan time from two weeks to just two days.
Marine viruses and microbes interact on a global scale, driving ecological processes and producing half of the oxygen we breathe. A study by an international team led by University of Arizona scientists reveals how viral communities maintain high regional diversity through passive transport by ocean currents.
Researchers have discovered a way to make pancreatic cancer cells more susceptible to oncolytic viruses by exploiting the communication between cancer cells and supportive cells, such as cancer-associated fibroblasts. This weakness can be exploited to improve treatment outcomes for patients with pancreatic cancer.
Researchers at UAB have created an artificial virus that can self-assemble, surround DNA fragments, and reach the nucleus of cells without biological risk. This innovation provides a promising alternative to traditional viruses in gene therapy, enabling the efficient delivery of therapeutic DNA and drugs directly to target cells.
The USGS has detected a novel, mixed-origin HPAI H5N1 avian flu virus in a green-winged teal in Washington State, differing from the well-known Asian H5N1 HPAI virus. The population-level impact of this virus on free-living wild bird species is currently unknown.
Recent study reveals that microbes like Sulfolobus islandicus can freeze in place when infected with a harmless virus, such as Sulfolobus spindle-shaped virus 9 (SSV9), to protect themselves. The dormant microbes recover if the virus is removed within 24-48 hours, otherwise they die.
Researchers discovered a molecular cause for parvovirus selectivity in cancer cells, revealing the PKCη/Rdx-driven phosphorylation of PDK1. This biomarker predicts therapy effectiveness and identifies cancer cells independent of growth factors.
Researchers have discovered a network of viruses that pose a threat to multiple species of bumblebees and managed honeybees, highlighting the urgent need for disease management strategies. The study found five viruses, including deformed wing virus, in wild bees across Great Britain.
A new approach to tackling alphavirus infections has been developed using the protein pentraxin 3, which plays a crucial role in promoting virus infection and disease. This breakthrough discovery paves the way for improved vaccine and drug development.
Researchers are creating a synthetic vaccine that mimics the structure of the live virus to provide a quicker, easier, and safer alternative. The goal is to eradicate polio without the danger of accidental release associated with traditional vaccines.
Researchers at Tel Aviv University identified a novel protein capable of targeting and inhibiting the activity of a protein essential to bacterial cells. This discovery may strengthen efforts to combat antibiotic-resistant infections and presents a potential breakthrough in the fight against superbugs.
Researchers found that even minimal mutations in viral RNA can make it too bulky for the capsid, preventing replication. The study used computer simulations and verified previous research on optimized RNA packing.
Researchers found that long-lasting hosts evolved more complex defenses against parasites, providing a survival advantage. The study used the Avida platform to model co-evolution between host and virus, revealing a surprising large proportion of 'switching' mutations in co-evolved hosts.
Researchers found that herpes simplex virus 1 rearranges telomeres to improve viral replication, suggesting a molecular mechanism for viral efficiency. The study also highlights the role of telomere proteins in protecting against viral infection.
Researchers found that immune mechanisms triggered by viruses differ depending on entry route, with Toll pathway activated for feeding-related infections. The study suggests that understanding these differences can help find targets to block human diseases transmitted by insects.
Researchers at NYU Langone Health found that infection with a common virus helped mice repair damaged intestinal tissue and restore their immune defenses. The study suggests that the virome, or natural presence of viruses in the gut, plays a crucial role in maintaining health and fighting infections.
A study found that flu viruses expressing specific avian hemagglutinins led to fatal infections in mice and caused significant cell damage in human lung cells. These findings suggest that certain hemagglutinins may induce programmed cell death, leading to enhanced disease severity.
Researchers have developed a self-repairing software called A3 that detects and eradicates malware, repairing damage and preventing re-infection. The software can repair complex security vulnerabilities in minutes without taking servers down.
Researchers analyzed the host range of canine parvovirus (CPV) and found that viruses in domestic dogs and raccoons could infect a wider range of wild carnivores than previously thought. The study identified specific genetic changes associated with host adaptation, suggesting that these mutations can overcome barriers to infection.
Researchers have discovered that multiple viruses share an L-shaped switch in their RNA genomes, which can be flipped to prevent replication. The discovery has implications for developing new drugs to inhibit viral replication, particularly for hepatitis C virus.
A recent study reveals that two viruses have led to the collapse of three amphibian species and impacted six others in northern Spain, causing severe disease and mass mortality.
A new study reveals that marine viruses are more important to microbial ecology below sunlit surface waters than previously suspected. The research focused on a sulfur-oxidizing bacterium called SUP05, which is dominant in oxygen minimum zones and has not been successfully cultivated in a lab setting.
A study from the University of Sydney reveals a 61% decrease in genital wart management among young women since the introduction of the free HPV vaccination program. The vaccine has been effective in reducing genital warts and their treatment costs, with no significant change in other sexually transmitted infections.
Researchers found the avian H3N8 flu virus, which killed harbor seals, can spread through respiratory droplets and pose a threat to humans. Human immunity to the virus is lacking, raising concerns about possible person-to-person airborne spread.
Scientists from Aalto University create ordered structures by mixing oppositely charged proteins and virus particles, enabling modular functionalization with various ligands. The method opens possibilities for biomedical and materials science research.
Researchers found that viruses infecting algae drive the life-and-death dynamics of massive algal blooms, with a single bloom fixing about as much carbon as an equivalent patch of rainforest. This has significant implications for climate and ocean carbon sequestration.
Researchers found that Deformed Wing Virus (DWV) is the most affected virus species by Varroa infestation, while Kashmir Bee Virus (KBV) peaks two years after initial infestation and disappears. The study highlights the importance of beekeeper awareness, mite monitoring, and efficient Varroa control.
A GW researcher has discovered an antibody that recognizes ancestral fossil viruses in the human genome, providing a new target for HIV-1 immunotherapy. This breakthrough could help overcome the virus's frequent mutations and improve treatment options.
Using lab-cultured bacteria as 'bait,' researchers sequenced complete and partial genomes of 10 million viruses from an ocean water sample, revealing distinct categories and enabling recognition of actual virus populations. This breakthrough enables scientists to study the ecology and evolution of viruses in nature.
Researchers discovered how viruses affect phytoplankton, like Emiliania huxleyi, altering global carbon cycle and marine food chain. Viruses rewire host lipid metabolism, diverting fixed carbon from traditional food web, with implications for ocean ecosystems.
Alicia Boole Stott and Ludwig Schlaefli showed that six platonic solids have four-dimensional counterparts, featuring strange symmetries. The spinorial construction explains these symmetries, shedding new light on both three- and four-dimensional geometries.
A new study reveals that late-stage sepsis triggers the reactivation of dormant viruses in the body, leading to secondary infections. Researchers found that 43% of sepsis patients had multiple viruses detected in their blood or urine.
Researchers at the University of Colorado School of Medicine have solved a biochemical mystery surrounding viral RNA molecules. The study reveals how these molecules mimic cellular RNAs as part of their strategy to infect cells and multiply, offering insights into potential treatments or vaccines against infectious diseases.
Researchers discovered that DNA relaxes to pack into virus heads at speeds determined by physics. The process counteracts the molecule's tendency to repel itself due to its negative charge.
Researchers found viruses force bacteria to burn sulfur reserves, releasing energy for viral replication. The study reveals a new microbial interaction in deep-sea environments, hinting that viruses act as agents of evolution in chemosynthetic systems.
Scientists found viruses that infect bacterial cells in deep-sea environments, forcing them to burn sulfur reserves and release energy. The viral genes are similar to those used by the infected bacteria, suggesting a genetic exchange that helps the viruses propagate.
Researchers at Ludwig-Maximilians-Universität München have identified the structural features that enable the innate immune system to distinguish viral from host RNAs. The RIG-I like receptors (RLRs) recognize specific patterns in viral RNAs, which differ from endogenous cellular RNAs.
The human immune system uses enzymes like ADAR1 to modify viral genetic information, rendering it useless for new virus particles. The study reveals how the cell protects itself from accidental import of viral RNA into the nucleus.
Researchers at Aalto University have successfully developed a novel nanocrystalline cellulose that effectively inhibits alphavirus infection in cells. The compound was found to prevent viral spread in 88-100% of cases, with no negative effects on cell viability.
Researchers have discovered that the bicolored shrew acts as a 'pathogen reservoir' for the Borna virus, transmitting it to horses. The virus is not directly contagious and requires an intermediate host to spread, highlighting the importance of keeping shrews away from stables to prevent transmission.