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Crystal study may resolve DNA mystery

A study by Rice University bioscientists has revealed the presence of a central metal ion critical to DNA replication and implicated in misincorporation. The research found that three metal ions are involved in the process, with the first supporting nucleotide binding and the second stabilizing the binding of loose nucleotides. This di...

SourceRice University·JournalNature Communications·TypeExperimental study·DateMay 9, 2022

Environmental DNA analysis to manage fecal contamination

A team of researchers has developed a new method using environmental DNA analysis to track the source of fecal contamination in surface water. By analyzing specific DNA sequences, they can identify the main contributors to pollution and potentially pinpoint areas with faulty wastewater treatment infrastructure or poor manure management.

SourceInstitut national de la recherche scientifique - INRS·JournalEnvironmental Monitoring and Assessment·DateFeb 24, 2022

New simple method for surveying amphibians: A vital contribution to conservation efforts

Researchers developed a simple and efficient method for surveying amphibians using environmental DNA analysis, which can be conducted by anyone without specialist knowledge. This technique resolves issues with conventional methods such as capture and observational surveys, allowing for more accurate monitoring of amphibian habitats.

SourceKobe University·JournalMetabarcoding and Metagenomics·TypeExperimental study·DateFeb 21, 2022

New assay shows promise for advancing personalized cancer treatment

Researchers have developed a rapid and affordable test to identify specific genetic mutations in cancer cells using SuperSelective PCR primers. This assay can detect rare mutations, enabling targeted therapy and monitoring minimal residual disease. The study demonstrates the potential of this approach for personalized cancer treatment.

SourceElsevier·JournalJournal of Molecular Diagnostics·TypeExperimental study·DateFeb 10, 2022

Powerful new tool makes coral reef monitoring faster, easier, cheaper

Researchers have developed a powerful new tool that can determine the diversity of hard corals on a reef by analyzing DNA in seawater samples. This method is faster, easier, and less expensive than traditional visual identification, allowing for more accurate coral reef conservation and restoration.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalFrontiers in Marine Science·TypeExperimental study·DateDec 6, 2021