Articles tagged with Neuroimaging
Researchers developed an experimental protocol to monitor brain activity in mouse models, finding that brain activity shifts from inner layers to cortex throughout the day. This discovery could lead to new methods for assessing fatigue and understanding mental health issues.
The study used advanced neuroimaging methods to identify early, network-level changes in over 3,000 individuals at varying levels of risk for psychosis. Individuals at high clinical risk exhibited early disruptions in brain network organisation despite mild clinical symptoms.
The MiniVolt microscope enables recording of both rapid electrical spikes and smaller sub-threshold voltage changes in freely moving animals. This allows for a more complete view of how brain cells process information during natural behavior, leading to potential new treatments for neurological disorders.
The EBRAINS Summit 2025 will bring together experts to assess how neuroscience can drive medical progress, digital innovation, and responsible data use. Preliminary results from the EPINOV clinical trial, integrating virtual brain technology for epilepsy surgery planning, will be presented.
Researchers have developed a new method to image brain tissue using X-rays, achieving unprecedented resolution and resolving the long-standing challenge of studying connectomics. The technique uses a specially designed epoxy resin and cooled stage to stabilize the sample, enabling the study of synapses and neural connections in three d...
Researchers at the University of Plymouth have successfully used transcranial ultrasound stimulation (TUS) to change the function of a deep region of the human brain, specifically the nucleus accumbens. This tiny element is triggered by enjoyable experiences and helps us learn behaviours that lead to rewards.
Researchers analyzed clips from Hollywood films to identify brain structures linking visual and tactile experiences. They discovered eight remarkably similar maps in the visual cortex, mirroring the body's organization in the somatosensory cortex.
Researchers identified five phases of brain structure, each supported by four turning points between birth and death, revealing key developments in cognitive performance, neural efficiency, and regional compartmentalization. The study provides context for understanding why brains develop differently at various stages of life.
A USC study mapped tiny structural differences in white matter among children and young adults with autism, pinpointing patterns that earlier methods would have missed. The findings highlight the importance of developing new methods to better understand brain differences in autism.
A new study found that individuals with a history of major depression showed higher MRI markers associated with neuroinflammation in the VTA, suggesting increased extracellular inflammatory processes. Current depressive symptom severity was associated with distinct microstructural changes indicating different underlying pathophysiologi...
Researchers will study neural mechanisms of visual perceptual learning (VPL) to generalize across the visual field, improving vision rehabilitation and AI systems. The project aims to develop a unified model of visual processing, VPL, and attention.
Researchers developed a novel method called cytoarchitecture-based link estimation (CABLE) to infer axonal pathways from routine histology, reconstructing three-dimensional whole-brain fiber tracts at cellular scale. CABLE outperforms existing neuroimaging tools in resolving complex geometries and has potential applications in psychiat...
A new study by Carnegie Mellon University's Wood Neuro Research Group uses advanced brain imaging and a digital visualization tool to better understand how pain is processed in the brain for people with sickle cell disease. The team found that patients had reduced connectivity across key brain networks linked to pain perception, partic...
A study published in Radiology found that soccer fans' brain activity is triggered by positive and negative emotions when watching their favorite team play. The researchers used fMRI to examine the brain's response to goal sequences from matches, revealing patterns of neural activation associated with social identity and fanaticism.
A new brain atlas developed by UCL researchers enables analysis of brain scans at an unprecedented level of detail, opening up possibilities for studying neurodegenerative diseases and ageing. The atlas uses AI to identify hundreds of brain regions in living patients quickly and consistently.
A mega-analysis of 16 neuroimaging studies found that brain activity in reward and social processing regions can predict which messages are well-received by both scanned individuals and broader audiences. Effective messages activate brain responses related to mentalizing, anticipating rewards, and evoking emotions.
Researchers have developed a new large-scale brain data resource that integrates data from five studies of brain development in children and young adults across three continents. The Reproducible Brain Charts (RBC) project provides a harmonized dataset for tracking changes in brain structure and function, allowing researchers to better...
Researchers discovered that brains and economies follow similar rules in crisis, using physics principles to predict collapse and recovery. The study found that networks closer to first-order transition show faster collapse and slower recovery after a crisis.
A University of Minnesota Medical School research team, led by Ziad Nahas, has been awarded a $4.4 million grant to explore how large-scale brain networks regulate mood in bipolar disorder. The team will test a novel type of brain stimulation called Personalized and Adaptive Cortico Electrostimulation (PACE) to relieve symptoms and ide...
Researchers have discovered a key role for the Frazzled protein in fruit fly neural circuits, revealing how it helps neurons form reliable connections. The study showed that when Frazzled is missing or mutated, neurons fail to form proper electrical connections, leading to communication breakdowns.
Recent advances in deep learning techniques have overcome limitations in spatial and temporal resolution of BOLD-fMRI. DL models improve image quality through super-resolution reconstruction, automate segmentation, and enhance registration, enabling finer localization of neural activity and more precise brain activity quantification.
Researchers used data from the Human Connectome Project to build computational models that linked connectivity with brain activation across various cognitive processes. The findings show a consistent correlation between connectivity and function, suggesting that specific patterns of connectivity can predict brain activity.
Researchers have discovered that deep sleep plays a crucial role in controlling cerebrospinal fluid dynamics, which is essential for clearing waste from the brain. During slow-wave sleep, changes in cerebrospinal fluid signals are time-locked to slow brain waves and other neural events.
A new study from Washington University School of Medicine found that social conflicts, particularly family fighting and peer bullying, were the strongest predictors of near- and long-term mental health issues in teens. The research also revealed sex differences in how boys and girls experience stress from peer conflict.
A new study reveals that astrocytes, a type of glial cell, are responsible for stabilizing memories through repeated engagement. The researchers found that Fos activity in astrocytes only occurs during recall, and that these cells can be activated to produce stable memories.
MetaSeg achieves the same segmentation performance as U-Nets but requires 90% fewer parameters, making medical image segmentation more cost-effective. The new approach leverages implicit neural representations to quickly adjust to new images and decode accurate labels.
A researcher is exploring the hidden functions of vascular-neuronal interfaces to uncover how blood vessels influence brain development and connectivity. The study aims to develop new therapeutic strategies for diseases caused by disrupted communication between blood vessels and neurons.
A study by UC Riverside researchers identifies a strong connection between demyelination and seizure activity in multiple sclerosis. The findings suggest targeted treatments could address the root cause of seizures without suppressing overall brain activity.
Researchers have developed an AI model that creates a detailed map of the mouse brain featuring 1,300 regions/subregions. The CellTransformer model uses spatial transcriptomics data to identify previously uncharted subregions of the brain, opening new avenues for neuroscience exploration.
Scientists have developed a device that allows them to stimulate three or five precisely defined points in the brain simultaneously, improving the technique of ultrasonic stimulation. This non-invasive method has the potential to treat various brain diseases, including Alzheimer's, epilepsy, and depression.
Adolescents who frequently prefer solitude show measurable differences in brain structure and function, with weaker connections and greater fragility in social circuits. Clinicians can help families recognize risks by spotting early patterns of persistent withdrawal, opening the door to strategies that may protect mental health.
Researchers developed a fiber-optic method to track Alzheimer's plaques in freely behaving mice, allowing for real-time monitoring and long-term tracking of pathological changes. The technique uses fluorescent dye to bind specifically to amyloid fibrils and provides a minimally invasive way to study disease progression.
Professor John O'Brien's research focuses on understanding the impact of electrical synapses and gap junction plasticity on the retina and other neurological functions. The study aims to identify proteins that control electrical synapse strength, shedding light on their role in human disorders such as autism and seizures.
A new study found that healthy habits such as optimism, good sleep, and social support are strongly linked to healthier brains. Study participants who reported the most protective factors had brains eight years younger than their chronological age, and their brains aged more slowly over time.
A $10-million grant from the Weston Family Foundation will fund a project at McGill University to discover new Alzheimer's biomarkers. The ultra-high-sensitivity whole body PET/CT scanner, Panorama GS, will aid in understanding disease progression and developing personalized therapies.
The VasCog-2-WSO criteria update provide operationalization and guidance on neuroimaging and fluid biomarkers for VCID diagnosis. This new standard aims to facilitate diagnostic consistency among clinicians and researchers worldwide.
Researchers have developed a miniaturized microscope capable of real-time, high-resolution imaging of brain activity in mice. The device uses a novel neural network to reconstruct images in 3D and is nearly the size of a grape.
The UTHealth Houston Novel Treatments for Acute Brain Injury Institute focuses on improving care for patients with acute brain injuries through research, clinical expertise, education, and community outreach. The institute aims to advance pharmaceutical and device therapies and train the next generation of neurocritical care experts.
Researchers developed a new method to correct for variations in brain imaging measurements, reducing bias and increasing the accuracy of studies on ADHD. The traveling-subject method demonstrated reduced measurement bias while maintaining sampling bias, revealing decreased brain volume in critical regions for cognitive functions.
A new study from the University of Turku found that AI systems can accurately evaluate social features from images and videos, comparable to human evaluations. The researchers compared AI's evaluations with those made by over 2,000 humans, showing that AI's results were consistently accurate.
Scientists have discovered that tiny brain vessels pulse to regulate blood flow through bursts of contraction and relaxation. The research reveals that these bursts originate from the walls of small arteries and spread through the vascular network in short intervals, providing insights into how the brain regulates its blood supply.
Researchers found neglected children had abnormalities in critical brain regions, including right corticospinal tract and superior longitudinal fasciculus, linked to behavioral difficulties. These findings provide objective markers for identifying children affected by neglect.
A study published by the American Psychological Association reveals that extreme liberals and conservatives exhibit similar brain responses to political content. The researchers used fMRI scans, skin conductance measures, and eye-tracking to analyze 44 participants with varying political ideologies and levels of extremism.
The Fork It Fund has awarded $1 million to support a major initiative at Stevens INI, accelerating scientific discovery by making critical research data more accessible worldwide. GAAIN is a global data-sharing platform connecting Alzheimer's disease and dementia-related data repositories from around the world.
Researchers found that brain maps of the hand and lips remained consistent even after amputation, contradicting previous views of reorganization. This study has implications for treating phantom limb pain and controlling robotic replacement limbs via neural interfaces.
Despite long-held assumptions, a new study reveals that the brain's somatosensory cortex holds a stable 'body map' even after limb loss. The findings have significant implications for treating phantom limb pain and restoring sensation in prosthetic limbs via brain-computer interfaces.
The TReNDS Center has received two new NIH-funded R01 grants aimed at tackling Alzheimer's disease progression and advancing multimodal brain imaging techniques in neuropsychiatric disorders. The center will develop flexible models to link data and uncover complex patterns in neuroimaging and genomics.
Scientists have successfully decoded inner speech using brain-computer interfaces (BCIs) with an accuracy rate of up to 74%. The BCI system can interpret neural activity related to thought processes, allowing individuals with severe paralysis or motor impairments to communicate more naturally and comfortably.
Researchers discovered a link between stomach rhythm and psychological well-being, finding stronger coordination is linked to higher levels of anxiety, depression, and stress. The study suggests the stomach's 'second brain' may play a crucial role in mental health diagnosis and treatment.
Researchers discovered a brain mechanism behind 'specific musical anhedonia,' where people experience no pleasure from music despite normal hearing and other experiences. Studies using the Barcelona Music Reward Questionnaire support this idea, showing reduced activity in the reward circuit when listening to music.
Researchers create breakthrough imaging system that shows sensory activity in real time, enabling them to distinguish between different sensations. The technique uses a genetically encoded voltage sensor to observe electrical signals from neurons and has major implications for treating chronic pain and sensory disorders.
Researchers aim to uncover how menopause and lifestyle factors shape brain aging in women during midlife. The three-year project will analyze MRI scans and health data from thousands of women worldwide to track changes in brain structure and connectivity.
Researchers at the Institute for Basic Science have discovered that excessive GABA produced by astrocytes impairs fear extinction in PTSD. A new brain-permeable drug called KDS2010 has reversed PTSD-like symptoms in mice, providing a promising therapeutic approach.
The largest neuroscience event will convene in San Diego from November 15-19, featuring over 10,000 presentations on various topics. Registered journalists will gain access to cutting-edge research, expert interviews, and press-only events.
Researchers explored neuroanatomy underlying social dominance in nonhuman primates, focusing on the uncinate fasciculus and its correlation with social dominance measures. The study found a significant correlation between this brain tract and social aggression, supporting human studies linking it to social dominance.
Researchers discovered a two-step mechanism where inhibitory neurons release nitric oxide to rapidly dilate blood vessels, followed by slower, localized vasodilation via astrocyte activation. This breakthrough sheds light on how neural signals are translated into blood volume changes in brain imaging.
A study published in Alzheimer's & Dementia found that regular opioid use is associated with a 20% increased risk of all-cause dementia and over 70% increased risk of dementia among those taking strong opioids. Regular opioid use was also linked to reduced brain volume, lower fluid intelligence, and higher risk of vascular dementia.
A NUS-led global study reveals that 30-minute functional MRI scans deliver up to 22% in cost savings while retaining or improving prediction accuracy. This finding could reshape how researchers design neuroscience and mental health studies, especially for hard-to-recruit populations.
Researchers at Stanford University have developed new technology to image brain waves, revealing three new types of brain activity. The ultra-sensitive optical instruments can detect signals of genetically engineered proteins and show neural activity across the majority of the mouse neocortex.
Researchers found that adults with autism perceive visual body information similarly to neurotypical adults, challenging long-standing assumptions about social difficulties in ASD. The study used fMRI to compare brain activity patterns in adults with autism and typically developing adults while viewing images of body parts.