Articles tagged with Neurons
Recent PsychENCODE research provides a better understanding of brain development and neuropsychiatric risks, with critical expression differences in genes identified during early brain development and adolescence. The findings highlight the importance of studying specific cell types and time points in brain development to model disease...
Stanford researchers have developed a way to study the firing of individual brain cells using only light, eliminating the need for invasive methods. The new approach measures subtle changes in cell shape when they fire, allowing for a cleaner and simpler way to study the brain.
A recent study by Harvard Medical School researchers has identified a critical nerve-signaling pathway that drives sustained pain following injury. The study found that neurons called Tac1 play a key role in pain-coping behaviors, but not in reflexive defensive reactions to external threats.
A new noninvasive technology detects nerve cell firing based on changes in shape, allowing for quantitative monitoring of visual function at the cellular level. This technique could be used to observe nerve activity in light-accessible parts of the body, such as the eye.
A study published in Cell Stem Cell found that glial cell development involves three stages and is regulated by specific transcription factors. The researchers discovered that the proteins NFIA, ATF3, and Runx2 play key roles in organizing glia-specific gene expression.
A Stanford study found that methotrexate damages brain cells, leading to cognitive impairment. Researchers identified a potential remedy and hope to improve treatment for cancer survivors struggling with debilitating side effects.
Scientists at Cold Spring Harbor Laboratory found that brain cells in mice associate sounds with emotions through experience and learning. The amygdala, a key brain region, shows specific patterns of neuron activity when animals are trained to fear or anticipate rewards.
Researchers at Cedars-Sinai Medical Center have discovered neurons that signal the detection of errors, offering insights into executive function capabilities and possible treatments for conditions like obsessive-compulsive disorder and schizophrenia. The study also found a single-neuron correlate of self-monitoring for errors in humans.
Researchers developed niosomes, a type of non-viral vector, to transfer genetic material into the brain. The innovative formulation uses lycopene as a helper lipid, improving transfection efficiency in neuronal and glial cells.
A single workout can activate neurons influencing metabolism for up to two days, according to a mouse study from UT Southwestern Medical Center. The finding provides an avenue to explore potential treatments to improve glucose metabolism in diabetes patients.
The company's discovery engine identified a series of compounds that shielded cells against alpha-synuclein-induced toxicity by inhibiting stearoyl-CoA desaturase. This finding suggests that inhibition of fatty acid desaturation could be a potential therapeutic approach for treating Parkinson's disease and other synuclein-based disorders.
Researchers at the Salk Institute discovered a framework that mimics how fruit flies detect novel odors, using a Bloom filter-like data structure. This new approach improved accuracy for detecting duplicates or anomalies in large datasets.
Research reveals that the Nax channel in circumventricular organs detects increases in body fluids' sodium levels, triggering sympathetic nerve activity and blood pressure elevations. The study identifies acid-sensing ion channel 1a as a key mediator of this process, opening new avenues for treating salt-sensitive hypertension.
The Blue Brain Cell Atlas provides detailed information on major cell types, numbers, and positions in all 737 brain regions, accelerating progress in brain science. The atlas is freely available online, allowing users to visualize brain regions and download data for new analyses and modeling.
Researchers at MIT found a mysterious RNA buildup in neurons that increases with age, reducing protein production and potentially contributing to neurodegenerative diseases. The discovery was made using a novel technique that allowed them to isolate and sequence messenger RNA from specific types of cells.
Scientists at the National Eye Institute have found that neurons in the superior colliculus are key players in allowing us to detect visual objects and events. The findings show that a specific population of neurons directly cause a behavior, and a mathematical model can predict behavior based on these neurons.
Researchers at Polytechnique Montréal have developed a technology that uses a femtosecond laser and gold nanoparticles to make precise incisions in cells, allowing for effective gene delivery. This breakthrough offers new hope for treating eye diseases such as glaucoma, retinitis, and macular degeneration.
Cytocybernetics is developing the Cybercyte for use with brain cells to study how drugs affect electrical activity in neurological disorders. The company will expand its focus beyond cardiac applications with the new funding.
A UCLA cell study has discovered the impact of head injuries on individual cells and genes, leading to serious brain disorders. The researchers found that hundreds of genes are adversely affected by mild traumatic brain injury, which can later lead to diseases such as Alzheimer's and Parkinson's.
Researchers discovered that secretin stimulates appetite suppression and increased brown fat heat production in mice. Human volunteers showed similar results, suggesting a link between secretin and satiation. This finding may lead to new approaches for treating obesity.
Researchers discovered that lab-grown kidney cells can contain rogue brain and muscle cells, making them imperfect models for human kidneys. However, they found a way to prevent most of these off-target cells from forming, which could accelerate progress in developing better treatments for kidney disease.
Researchers at Carnegie Mellon University have developed a new method that uses neural networks to analyze single cell RNA sequencing data, identifying key genes and cell subtypes. This approach enables the analysis of all cell types, providing a method for comparative analysis.
Researchers developed a technique to create tissue-like structures from human stem cells, which were then transplanted into mouse brains. This approach showed improved cell survival and differentiation compared to traditional methods.
Researchers at Yale University have identified a new fluorescent protein, VARNAM, that allows for live neurons to glow red when activated, making it possible to monitor brain activity in a less invasive way. This breakthrough enables scientists to capture complex brain activity spikes in multiple systems.
Researchers solved a 125-year-old brain mystery by discovering that perineuronal nets modulate electrical impulses in the brain. Without these structures, inhibitory neurons fire too slowly, leading to seizures. The findings have implications for various forms of acquired epilepsy and may lead to new treatments.
Researchers identified a unique frequency of brainwaves associated with communication between the amygdala and hippocampus, which correlates with worsening mood related to depression and anxiety. The study used intracranial EEG to measure brainwave activity in epilepsy patients and found fluctuations in electrical activity at a specifi...
A study in mice found that eliminating microglia cells eliminated inflammation following traumatic brain injury, offering a potential target for treatment. The research aims to understand cellular-level changes associated with sports-related concussion and other brain injuries.
New analysis improves knowledge of physical, biological systems by studying time that components take to influence each other. Researchers developed formulas to understand how this affects synchronization in oscillator systems, which are common in nature and technology.
Researchers found that adolescent marijuana use reduces perineuronal net formation around inhibitory cells, affecting decision-making and self-control. This alteration may have long-term consequences for brain function and behavior.
Biopsychologists demonstrate that subtle timing differences in the right hemisphere allow it to control specific functions, while the left hemisphere delays its activity. The study reveals a sophisticated mechanism underlying hemispheric dominance.
Researchers from UCI School of Medicine have found that neurons in blind rats' brains function normally after receiving fetal retinal cell transplants. The study reveals the potential for retinal transplants to treat retinal degeneration in people.
Rhesus monkeys' brain neurons in the orbitofrontal cortex differentiate between faces and nonfaces before recognizing emotional content and social categories. The specialized neurons are unaffected by auditory cues or learned rewards associated with faces.
Researchers at the University of California, Irvine, have successfully restored vision in rats with severe retinal degeneration through cell transplantation. The study demonstrates that donor cells can integrate into the retina and generate nearly normal visual activity in the brains of blind animals.
New studies reveal extracellular vesicles transport molecular signals, signs of disease, and stress effects onto offspring. These particles may help diagnose neurological disorders with similar symptoms.
The NIH BRAIN Initiative Cell Census Network has released its first data set, featuring the molecular identities of over 1.3 million mouse brain cells and anatomical data from 300 brains. This comprehensive characterization aims to integrate molecular, anatomical, and functional data on cell types in mice, humans, and non-human primates.
Researchers have created a groundbreaking cellular atlas of the brain, revealing over 70 different types of neurons, their locations, and functions. This breakthrough technology allows for unprecedented insights into brain organization and behavior.
A research group from Kumamoto University discovered a new neurogenic mechanism responsible for brain development, revealing that Matrin-3 regulates the differentiation of neural stem cells into neurons. The absence of this protein causes disordered differentiation and collapse of brain layer structure.
Astrocytes communicate with neurons to regulate sleep time in fruit flies, a finding that suggests a similar mechanism may exist in mammals. The study used fruit flies to identify mechanisms of sleep regulation and found that a protein called Eiger plays a critical role in regulating sleep.
A recent study published in Nature suggests that gut bacteria play a crucial role in regulating movement in fruit flies. The researchers found that specific bacterial strains, such as Lactobacillus brevis, can slow down the speed of germ-free flies by fine-tuning levels of carbohydrates.
The Paul G. Allen Frontiers Group has awarded $13.5 million to 10 researchers studying lymphoma, neuroimmunology, nuclear biophysics, and brain cell function. These studies aim to shed light on Alzheimer's disease and develop new treatments for blood cancers.
Researchers identified the paraventricular thalamus as a key player in tracking important details for animals to learn. The study's findings suggest that the brain can adapt its focus on good and bad outcomes based on context, which could lead to new treatments for drug addiction.
A research team led by Professor Byung-Chang Suh has observed the dynamic combination of alpha 1 and beta subunits in calcium channels, revealing competitive replacement and stability. This breakthrough enables precise control of calcium ion inflow inside cells and opens a new horizon for treating high blood pressure and brain diseases.
A new study published in Frontiers in Behavioral Neuroscience confirms the potent relaxing effects of lavender and its active compound linalool. The research suggests that the scent of linalool must be smelled, not absorbed, to exert its calming effects.
A study reveals how a single mutation in the GFAP protein, the most common protein in astrocytes, produces devastating effects on brain cells. The mutated protein causes widespread tangles and disturbs cellular processing units, reducing myelin formation.
A new study found 'timing cells' in the brain that turn on when an animal waits, allowing it to measure a time interval. The research could lead to early-detection tests for Alzheimer's disease by asking people to judge how much time has elapsed.
Scientists developed a new method to record limb control neural circuits in fruit flies using two-photon microscopy. The study found different patterns of activity across neurons during movement and behavior, including walking and grooming.
Researchers have developed memristors that mimic the brain's ability to process information efficiently and adapt to changing conditions. The new devices, made from niobium-doped strontium titanate, can 'forget' and retain memories, making them suitable for future electronic brains.
Researchers found a brain region strongly connected to food choice decisions, suggesting its potential use in developing therapies for healthy eating. The ventral pallidum area was activated when rats preferred certain foods, indicating context-dependent decisions.
Researchers have developed a new approach to understand cancer's complex causes, enabling the analysis of multiple gene mutations simultaneously. This will accelerate the development of new treatments and provide insights into strategies for stopping cancer formation and spread.
Researchers at UCL have identified a new mechanism for neural crest cells to move from the back of the head to the front, crucial for forming facial features. This discovery could help understand how facial defects form and pave the way for developing new therapies.
Researchers developed a new way to engineer rhodopsin proteins, enabling the creation of tools with distinct properties. This technique doubles the number of available optogenetics tools, allowing for more precise experiments and advancing neuroscience research.
Researchers at Tufts University have developed 3D human tissue culture models for the central nervous system that mimic brain structure and function. The models allow for the exploration of cell interactions, disease progression, and response to treatment, enabling the study of neurodegenerative diseases like Alzheimer's and Parkinson's.
Researchers find that the autonomic nervous system directly controls stem cell proliferation in the intestinal lining and potentially other parts of the body. This discovery opens up new avenues for targeting cancer stem cells or inducing desired tissue growth through targeted drug delivery.
Researchers at Osaka University have developed an AI-based system to track individual fluorescently labeled molecules in living cells. The system can analyze hundreds of thousands of molecules in a short period, providing reliable data on molecule status and dynamics.
Researchers found altered patterns of neuron activity in the brain controlling reproductive endocrine systems in mice with epilepsy. The differences in activity in female mice fluctuated across their reproductive cycles, suggesting a dynamic connection between epilepsy and reproductive health.
Researchers transplanted human brain cells into mice brains to study the development and function of these cells in a natural environment. The study found that brain cells from individuals with Down syndrome were less coordinated but more stable than those without the condition.
A recent study from CNRS has cast doubt on the connection between magnetite particles and Alzheimer's disease, as previous research suggested that magnetite could cause oxidative stress and lead to neuron degeneration. The new findings suggest that magnetite is unlikely to be involved in this process.
Researchers are exploring ways to speed up and enhance the recovery of the sense of taste after a significant injury. By understanding how IL-1 signaling works in the body, they hope to develop novel treatments to aid regeneration and recovery. In mice, studies have shown that IL-1 plays a crucial role in repairing the taste system.
Research by Johannes Kohl identified the medial preoptic area (MPOA) neurons bearing Galanin as critical for parental behavior in mice. The study found that individual pools of these neurons control specific components of parenting, such as motor control and natural reward circuitry.
Researchers at the Institute of Molecular Pathology Biomarkers at the University of Extremadura have discovered a new biomarker for Alzheimer's disease of sporadic origin, protein STIM1. A deficiency in this protein has been linked to calcium ion transport abnormalities, which can lead to neurodegeneration and cell death.