Articles tagged with Blood
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A multi-disciplinary team at Harvard's Wyss Institute developed an electrochemical diagnostic sensor platform for multiplexed detection of clinically relevant biomarkers in whole blood. The device accurately detects three different sepsis biomarkers simultaneously and has the potential to revolutionize point-of-care diagnostics.
A new study found that a gene-based blood test can accurately monitor treatment progress in people with late-stage melanoma, allowing for swift treatment modification and potentially saving lives. The test targets the most common mutations in melanoma cells, detecting DNA fragments released by dying tumor cells.
A new algorithm detects hidden fingerprints in routine blood test results to identify people silently developing liver cirrhosis. The CIRRUS algorithm has an accuracy rate of 90% and can pick up over 70% of cases months or years before emergency admissions.
A new study by researchers from Linköping University suggests that long-term stress is a risk factor for heart attacks. Cortisol levels in hair samples were found to be statistically significantly higher in individuals who suffered a heart attack, even after adjusting for other cardiovascular risk factors.
A new drug, semaglutide, has been shown to cut body weight by 20% in a major global study involving over 1,900 participants. The study, published in the New England Journal of Medicine, found that three quarters of people who received the drug lost more than 10% of their body weight.
Researchers observed a young vampire bat pup being adopted by an unrelated female after its mother died, revealing intimate details about changing social relationships between the mother, pup, and adoptive mother. The study highlights the importance of grooming and food-sharing interactions in forming these relationships.
Researchers found that Black individuals show signs of diminished heart muscle strength and higher blood pressure from early childhood, increasing the risk of congestive heart failure. Midwall fractional shortening analysis revealed a decrease in cardiac muscle function over time, associated with increased risk.
Researchers found that lead levels in songbirds' drinking water impaired their ability to produce normal vocalizations and attract mates. The study suggests that even low levels of lead can have negative effects on the brain and learning abilities of these birds.
Researchers developed an enhanced CMV detection method that accurately detects the infection in newborns with almost 90% accuracy. This improvement enables earlier intervention, which can improve hearing, speech, language, and intellectual/neurodevelopmental outcomes for affected children.
A new study found that some COVID-19 patients have an unbalanced ability to break down clots, contributing to a high bleeding risk. This imbalance is linked to a potential clinical biomarker seen in later stages of the disease and may be consistent with recent trial pauses.
The immune system surveils the brain from a distance and only enters when it finds a problem. This finding explains why the brain was thought to be immunoprivileged. Targeting immune cells at surveillance sites may lead to new treatments for conditions driven by brain inflammation, such as multiple sclerosis.
A Danish research team has discovered a new control mechanism in the innate immune system, involving the ITIH4 protein. The study found that ITIH4 inhibits proteases via an unknown mechanism, preventing damage to healthy cells.
Researchers at UBCO's Heart Valve Performance Lab have developed a novel bileaflet mechanical heart valve that functions like the real thing, improving blood flow and preventing clots. The design incorporates a slight twist to mitigate clotting risk and enhances overall performance.
University of Kentucky researchers discovered that low blood amylin levels may protect against Alzheimer's disease progression, suggesting a potential therapeutic target. The study found that modulating blood amylin levels could improve cognitive decline and slow the disease.
Researchers studied 18 men's livers after a day of eating and drinking, finding some responded by increasing fat storage while others reduced it. The study suggests that high carbohydrate consumption may protect the liver, contradicting typical associations with alcohol.
A new review describes the current status of commercial assays for Procollagen type I N-propeptide (PINP) and C-terminal telopeptide of type I collagen (β-CTX) in blood. The authors recommend harmonization or standardization of these assays to improve clinical implementation and international multicentre trials.
Researchers discovered hundreds of previously unknown genetic variations affecting small molecule concentrations in the blood, which can impact diseases such as diabetes and eye disorders. The findings provide valuable biomarkers for clinical diagnosis and therapy.
A new protocol has been established to evaluate patients for elective surgeries following COVID-19, taking into account the high risk of complications and clinical uncertainty. The guidelines include minimum recovery times, patient history assessments, and objective testing to determine safe surgery procedures.
Researchers found that laypeople underestimate blood loss in female victims more than male victims, regardless of volume, and perceive it as less life-threatening. This knowledge can inform the design of training programs to teach people how to respond effectively in emergency situations.
A large-scale international study found a panel of 15 gut microbes associated with lower risks of common conditions. Diets rich in healthy foods encourage the presence of these beneficial microbes, which are linked to improved health outcomes.
Engineers developed a new technique to eliminate particularly tough blood clots by using engineered nanodroplets and an ultrasound drill to break up the clots from the inside out. In vitro testing showed promising results, with the use of nanodroplets, ultrasound, and drug treatment reducing clot mass by 40%, plus or minus 9%.
Global campaigns to eliminate tropical parasitic worm infections require better diagnostic tools. Researchers at WashU Medicine are developing improved diagnostics with a $2.95 million grant from the Bill & Melinda Gates Foundation.
A new study found that lower hydroxychloroquine blood levels are associated with a higher risk of clots in lupus patients. By monitoring blood levels, clinicians may be able to reduce clotting rates by up to 12% with increased dosing.
A study published in PLOS Pathogens reveals that mosquitoes feeding on blood multiple times increase malaria transmission potential, shortening the incubation period and making disease control more challenging. The research suggests that younger mosquitoes with reduced reproductive ability may contribute to infection, undermining curre...
Researchers at EPFL have developed a miniaturized endovascular device that can explore capillaries without causing tissue damage. The technology harnesses hydrokinetic energy and uses magnetic steering to navigate the vascular system.
A collaboration of three clinical trial platforms has paused enrollment for critically ill COVID-19 patients due to the lack of improvement in outcomes with full-dose anticoagulants. Moderately ill hospitalized COVID-19 patients can still be enrolled, and the trials will continue to analyze data.
A study of over 1,400 protein-coding genes resolved the mystery of fleas' placement in the insect tree of life. Fleas are classified as scorpionflies, evolving to feed on vertebrates between 290 and 165 million years ago.
A new study found that many weight loss surgery patients in the UK are not receiving annual nutritional monitoring and weight checks as recommended by clinical guidelines. This can lead to serious health consequences, including weight regain and nutrient deficiencies. The study's lead researcher calls for improved support for GPs and p...
A new study by Michigan Medicine researchers found that pulse oximeter readings may be less accurate in Black patients than in White patients, leading to potential mismanagement of treatment. The findings suggest that device makers may need to make changes to ensure accurate readings for all patients.
A new study from University of Alberta researchers found that women are at a 20% higher risk of dying or experiencing heart failure after a heart attack compared to men. The study examined data on over 45,000 Canadians who were hospitalized for their first heart attack between 2002 and 2016.
Researchers discovered biomarkers associated with COVID-19 immunopathology and multi-organ damage, enabling early identification of patients at risk of severe symptoms. The study's findings have potential for developing prognostic classification models to target treatments accordingly.
A new AI tool, AI-COVID, uses routine blood work to assist clinical labs in ruling out COVID-19 infection. The software achieved an area under the curve (AUC) of 0.91 and high sensitivity of 95% while maintaining moderate specificity.
A study from the University of East Anglia found that blood biomarkers such as cholesterol, inflammation, and liver function can predict future disability and healthcare demand. The researchers also discovered a pro-rich inequity in health care use, where people with higher incomes are more likely to seek medical attention.
Researchers at the University of Pittsburgh School of Medicine have developed a method to create lab-grown liver organoids with blood- and bile-handling systems using synthetic biology and machine learning. The resulting organs can mature faster than natural organs, extending the life of mice with failing livers.
Researchers at Lund University developed an app that predicts Alzheimer's disease risk based on blood biomarker levels, providing a more reliable and accessible early diagnosis method than current cerebral spinal fluid (CSF) analyses.
A study published by the American Academy of Neurology found that Black people have a higher risk of ischemic stroke due to blood clots, which cannot be fully explained by known risk factors. The researchers identified differences in left atrium structure and function between Black and white participants.
Researchers found that flavanol-enriched cocoa drink improved blood oxygenation levels in the brain, leading to enhanced cognitive performance. Participants completed complex tasks faster and with higher accuracy after consuming the flavanol-rich drink.
Researchers found a significant association between COVID-19 infection and an increased risk of mortality due to blood clots. The study suggests that thromboembolism may be a critical factor in COVID-19-related deaths, particularly among hospitalized patients.
Researchers used computer modeling to investigate the mechanisms behind silent hypoxia in COVID-19 patients. They found that a combination of biological factors, including damaged lung tissue, blood clotting, and air-to-blood flow mismatch, contribute to low oxygen levels. This understanding can inform treatment decisions for clinicians.
Research reveals greater mosquito susceptibility to Zika virus, fueling global epidemics and congenital abnormalities. The invasive subspecies of Aedes aegypti has marked preference for human blood and is effective in transmitting the virus.
Researchers at UIC are conducting three national NIH studies to investigate the safety and effectiveness of various types of blood thinners for treating adults diagnosed with COVID-19. The trials aim to prevent life-threatening cardiovascular or pulmonary complications, including stroke, pulmonary embolism, and heart attacks.
Researchers at Baylor College of Medicine have made significant discoveries about the 3D structure of mammalian ferroportin, revealing two iron-binding sites and a unique mode of action. This new understanding has potential implications for treating iron overload diseases, such as anemia and cancer.
Researchers identify blood biomarkers indicative of brain injury in COVID-19 patients, offering potential for timely diagnosis and cost-effective treatment approaches. The study highlights the increased risks of persistent neurological deficits, psychiatric disorders, and neurodegenerative diseases associated with COVID-19.
Researchers found that masks have minimal effects on lung function, even in healthy individuals, and do not increase the risk of shortness of breath or difficulty breathing. The study suggests that wearing a mask can be uncomfortable but does not impact cardiopulmonary function.
A new study by George Washington University researchers found that high-dose anticoagulation may be ineffective and even harmful for patients with COVID-19. The study compared clinical outcomes between patients treated with standard low-dose blood thinners and those receiving higher doses, finding no additional benefit.
Researchers at UHN have discovered a simple method to reverse alcohol intoxication by accelerating the elimination of ethanol from the body through hyperventilation. The device, small enough to be made anywhere in the world, uses a valve system and mask to remove excess carbon dioxide while maintaining normal blood levels.
Researchers propose that declining hip fracture rates may be linked to generational differences in lifetime lead exposure, with bone mineral density and risk of fractures decreasing as lead levels decrease. The authors suggest that assessing lead levels in bones removed during hip replacements could help validate this hypothesis.
A recent study published in Gastroenterology identified rare and common genetic variants that significantly increase the risk of developing life-threatening blood clots in IBD patients. The research suggests that genomic medicine could help lower this threat, enabling physicians to provide more precise care.
Researchers found that neurofilament light protein levels in the blood can predict stroke severity and prognosis, as well as anticipate future recovery. Higher NFL levels forecast worse functional outcomes and shorter survival time after a stroke. This discovery establishes NFL as a promising prognostic biomarker for stroke.
A new medication, centhaquine, has been found safe and effective in treating severe blood or fluid loss caused by trauma. The study showed significant improvements in patient outcomes, including reduced mortality rates and improved blood pressure and organ function.
A recent study published in the Journal of Neurology, Neurosurgery & Psychiatry found that COVID-19 is associated with worse stroke outcomes, particularly among people of Asian descent. The study revealed a significantly higher mortality rate and more severe strokes among patients with COVID-19 at stroke onset compared to those without.
A study published in the British Journal of General Practice found that poor awareness of Heart Failure with preserved Ejection Fraction (HFpEF) leads to missed diagnosis and treatment opportunities. The condition affects half of all heart failure cases in England, but frequently goes undiagnosed due to lack of understanding among clin...
A new study from Queen Mary University of London discovers that certain small molecules in patients' blood can predict response to disease-modifying anti-rheumatic drugs (DMARDs). Up to 50% of RA patients are unresponsive to treatment, and the research provides potential solutions for predicting patient responsiveness.
Researchers identified a new prognostic laboratory sign for imminent postoperative thrombosis, which appears on the first postoperative day. Early detection using this sign can help prevent life-threatening thrombotic complications and improve patient outcomes.
A large observational study found that regular consumption of omega-3s EPA and ALA can decrease the risk of death three years after a STEMI, with both types providing unique protective qualities. Walnuts were also shown to have significant benefits due to their high content of alpha-linolenic acid.
Researchers developed a more precise screening index to identify areas with high levels of chronic lead exposure in children. The method uses established risk factors, including poverty and housing built before 1950, and can be applied to any area in the US.
Researchers found a distinct DNA methylation signature in cord blood of newborns with autism spectrum disorder (ASD), spanning regions linked to early fetal neurodevelopment. The findings may hold clues for early diagnosis and intervention.
Hospitalized COVID-19 patients taking daily low-dose aspirin had lower risk of ICU admission, ventilation, and dying from the virus. The study found a 44% reduction in mechanical ventilator use, 43% decrease in ICU admission, and 47% decrease in hospital death compared to those not taking aspirin.
Researchers developed a simple blood test to distinguish between pancreatic cancers that respond to treatment and those that do not. The test detects the levels of a sugar called sTRA, which is produced by a certain subtype of cancer and escapes into the bloodstream.
A new study published in The Journal of Physiology found that administering a low dose of ketamine to healthy individuals does not alter their ability to tolerate simulated major blood loss. This study provides valuable insights for medical personnel when choosing pain medication for serious injuries with accompanying blood loss.