Articles tagged with Blood
A large epidemiology study found associations between higher HDL and apoA1 levels with a lower risk of ALS. Lower LDL and apoB levels were also linked to decreased risk. These findings may support population screening and preventative therapy for ALS.
The study found large reductions in uninsurance and improvements in blood pressure and blood sugar control among Hispanic and Black patients after Medicaid expansion. The first five years of expansion were associated with significant benefits for these populations.
Researchers examined changes in life expectancy after allogeneic blood or marrow transplantation over four decades. The study found improved survival rates and reduced risk of death among transplant recipients.
A mechanical engineering faculty-researcher at RIT is developing a microfluidic device to improve the detection of drug-resistant bacteria in blood, which can cause severe infection and death. The goal is to detect these strains early, allowing for prompt treatment and recovery.
A recent study found that individuals with COVID-19 are at a higher risk of developing phlebitis and thrombophlebitis, as well as blood clots in the leg and lung. The study also identified associations between general COVID-19 susceptibility and increased blood clot events and circulatory diseases.
A new study from Uppsala University found that genetic tests are more accurate than traditional blood tests in determining the risk of cardiovascular diseases. The study analyzed data from 500,000 subjects and discovered a significant link between blood group genetics and coagulation proteins.
Researchers found Prozac reduces lipid concentrations in monkey brains, linked to potential side effects in young patients. The study suggests dietary changes may alleviate adverse effects by influencing lipid synthesis.
A clinical trial shows that full-dose blood thinner treatment reduced the need for organ support and improved hospital outcomes in moderately ill COVID-19 patients. However, this benefit was not seen in critically ill patients requiring intensive care.
Researchers at the University of Basel developed a breath test to measure treatment success in epilepsy patients. The test provides immediate results without requiring a blood sample, allowing doctors to adjust medication quickly and precisely tailored to individual patients' needs.
Researchers analyzed patient specimens and clinical trial data from thousands of patients to assess the importance of immune cell molecules called Fc gamma receptors (FCGRs) in the therapeutic efficacy of two antibody drugs. High levels of FCGR2B on tumor cells were found to prevent rituximab efficacy, while obinutuzumab was not impact...
A world-first study found that cancer patients receiving chemotherapy intravenously have more than double the risk of developing a blood clot or thrombosis if the vein is too small and the catheter occupies more than 45% of the vein. Researchers identified specific limits on catheter-to-vein ratios to reduce risks for cancer patients.
Researchers compared various race-free equations and found that removing race adjustments increases eGFR values for Black patients, leading to more chronic kidney disease stage reclassifications. Blending or direct removal of race coefficients resulted in decreased eGFR estimates.
Researchers analyzed Neandertal and Denisovan genomes to identify blood groups, confirming their African origin and Eurasian dispersal. The study also found evidence of low genetic diversity and possible demographic fragility, shedding light on the disappearance of Neandertals.
A study analyzing ancient DNA has uncovered new information on the blood types of Neanderthals and Denisovans. The analysis reveals consistent African origins and increased vulnerability to diseases affecting fetuses and newborns, confirming previous evidence of low genetic diversity leading to eventual demise.
A proposed Canadian Immunization Services model could provide a coordinated approach to vaccination across the country, addressing fragmentation in data sharing, vaccine procurement, and supply chain management. The independent not-for-profit corporation would be funded by provinces, territories, and potentially the federal government.
A scientific review suggests a disruption in blood clotting and immune system may contribute to psychosis development. The researchers propose that an imbalance of these systems leads to inflammation, which contributes to the development of psychosis.
A novel body tissue adhesive incorporating snake venom has been developed to stop life-threatening bleeding in seconds. The 'super glue' works with visible light and offers 10 times the strength of existing fibrin glue, cutting blood clotting time in half.
Middle- to older-aged adults who eat at least three servings of whole grains daily have smaller increases in waist size, blood pressure, and blood sugar levels over time. Whole grains may protect against heart disease by reducing these risk factors.
Researchers found that a type of echocardiogram can predict which COVID-19 patients are most at risk of developing atrial fibrillation, a condition that increases the risk of heart failure and stroke. Patients with high levels of certain biomarkers in their blood also showed increased risk.
Researchers at Johns Hopkins Medicine report a potential noninvasive biomarker for tracking gene editing therapies in early-stage Huntington's disease. By measuring blood volume in the brain, they found that suppressing the mutant huntingtin gene can normalize altered arteriolar blood volumes and delay or prevent symptom development.
A longitudinal study of 358 diabetics found that proteins ANGPT1, TNFSF12, and FGF20 are associated with slower kidney decline. These proteins may help identify individuals at higher risk of diabetic kidney disease, enabling earlier interventions and treatment.
A recent study has made a breakthrough in understanding the process that leads to pulmonary embolism, a condition that kills over 2,000 people in the UK each year. Researchers have identified a protein called fibrin as crucial in stabilizing clots and preventing fragments from breaking loose.
A new study published in Neurology found that trying more than one time to remove blood clots during endovascular treatments for ischemic strokes was associated with increased disability and brain damage. Researchers suggest aiming for a single attempt at removal with new devices, highlighting the need for further development.
The NIH ACTIV-4B trial found that not treating certain symptomatic but stable outpatients with anticoagulant or antiplatelet therapy may be the best course of action, suggesting a very low rate of thrombotic complications. This recommendation has immediate implications for prophylactic treatment and management of mild COVID-19 symptoms.
Researchers successfully engineered yeast to produce spermidine, a natural molecule that induces autophagy, in hopes of addressing age-related diseases. The production yield reached 2.3 grams per liter, paving the way for fermentation-based manufacture of polyamines and their analogues.
A new study highlights the high risk of kidney failure and cardiovascular complications in patients with primary nephrotic syndrome, particularly those with focal segmental glomerulosclerosis. Adults with this condition are 19.63 times more likely to develop kidney failure over a median follow-up period of 4.5 years.
Researchers found that COVID-19 patients have higher levels of pro-clotting VWF molecules and lower levels of anti-clotting ADAMTS13. This disruption leads to severe blood clots, which can be life-threatening.
A new device that fits over a person's ears can measure real-time changes in blood alcohol levels through the skin. The device collects gas released through the skin and uses an ethanol vapour sensor to calculate ethanol concentrations.
A study published in Environment International found high levels of lead in indigenous people living in Peruvian Amazonia, with the highest concentrations found near oil extraction areas. The research, led by Cristina O'Callaghan-Gordo, highlights the need for urgent action to address the potential health effects on these communities.
Women are more likely to experience acute aortic dissection with older age and different presenting symptoms, leading to delayed diagnosis and treatment. The study highlights the need for sex-directed strategies to improve outcomes in female patients.
A clinical trial found an implantable device is more than three times more effective in detecting atrial fibrillation in ischemic stroke patients. The device could prevent disabling strokes by almost 70% if detected early.
A study published in Nature Metabolism found that specific proteins in the blood can predict an individual's trainability and response to exercise. The researchers identified 147 proteins related to cardiorespiratory fitness, which improved their ability to predict an individual's change in VO2max.
A new study published by the American Heart Association found that adults with OCD were more than three times as likely to experience an ischemic stroke, with the greatest risk among older adults. Researchers also discovered that medications used to treat OCD did not increase the risk of stroke.
The research team found that tenascin-C plays a crucial role in damaging vision cells following ischaemia. In mice without tenascin-C, retinal function improved after ischaemic damage, and fewer photoreceptors died.
A study of 1,095 patients with COVID-19 found abnormal blood-oxygen levels and breathing rates are strong predictors of poor patient outcomes. Researchers recommend monitoring for these signs at home or seeking medical attention earlier to potentially save lives.
A new study published in JAMA Network Open found that a game-based program increased physical activity levels among diabetes patients by an average of 503 steps per day. The program used wearable devices and digital scales with personalized goals to encourage competition, collaboration, or support from family members.
A new study on the 25 million-year-old fossil skull of Aetiocetus weltoni reveals that it had both teeth and baleen in adulthood. The discovery provides evidence of a major shift in feeding behavior from raptorial carnivory to filter-feeding, and sheds light on the evolution of modern baleen whales.
A new type of coronary artery stent is being developed with ultra-low profile struts and a smart surface that can help improve healing and prevent blood clots. The stents aim to reduce the risk of restenosis and thrombosis, which occur in 3-10% of cases.
A study found that exposure to the 2016 US presidential election was associated with an increase in potentially life-threatening cardiac events. The research, conducted in North Carolina, showed a 77% rise in the risk of arrhythmias during the election period compared to control periods.
A predictive model has been developed to identify pediatric patients at risk of developing blood clots or venous thromboembolisms. The model includes 11 risk factors and has been validated on over 44,000 separate admissions. In a trial called CLOT, the model is being used to inform personalized prevention plans for high-risk patients.
A new study found that combining EPA and DHA in popular supplements may blunt heart health benefits, while higher EPA levels alone lowered the risk of major cardiac events. Higher DHA levels worsened health outcomes, suggesting that not all Omega-3s are created equal.
A recent study found that using a rapid, high-sensitivity troponin T testing protocol did not improve patient outcomes after one year. In fact, patients who received this protocol were more likely to experience a heart attack or death compared to those in the standard-care group.
A large international study led by McMaster University found that removing the left atrial appendage significantly cuts the risk of strokes by more than one-third in patients with atrial fibrillation. The procedure is simple, quick, and safe for the majority of heart surgery patients with this condition.
Researchers found that left atrial appendage occlusion significantly reduced stroke risk by 33% in patients with AFib or atrial flutter. The procedure, performed during heart surgery, added less than 10 minutes to the operation and demonstrated long-term safety.
A new study by Rutgers researchers found that COVID-19 can trigger a rare recurrence of upper extremity blood clots, requiring vigilant monitoring and treatment. Patients with a history of deep vein thrombosis or chronic medical conditions are at higher risk for recurrence.
Researchers at Hospital for Special Surgery found that oral tranexamic acid (TXA) is non-inferior to intravenous TXA in preventing blood loss during total knee and hip replacement surgeries. The study suggests that oral administration of TXA may be logistically easier, less costly, and equally effective as IV TXA.
A recent study led by University College London researchers has found that mild COVID-19 infections do not lead to lasting heart damage. The study of 149 healthcare workers with mild COVID-19 infections showed no significant differences in heart structure or function compared to healthy controls.
Researchers created a probe that glows when detecting an enzyme associated with blood clots and strokes. The probe, made up of two components, can host fluorescent molecules and detects an increase in fluorescence intensity when the probe comes into contact with the enzyme.
A team of researchers at Massachusetts General Hospital has identified a consistent protein signature in patients with severe COVID-19. The study found that this signature is associated with an immune response, but also with older patients who have chronic diseases and weakened immune systems.
A new study found that high-intensity cycling sprints can increase maximum oxygen consumption, anaerobic power, and total blood volume, improving aerobic exercise endurance. These results may encourage people to exercise with a short and effective workout that only takes 10 minutes a day.
Researchers have found a link between certain blood types and increased risk of diseases such as kidney stones, pregnancy-induced hypertension, and bleeding conditions. A study scanning health data on over five million people revealed new connections and confirmed previously reported associations.
Researchers predict and capture the reversal of blood droplet flight due to gun muzzle gases, impacting forensic analysis of bloodstain patterns. The study also reveals the breakup of blood droplets in flight, affecting the formation and size of blood droplets.
Researchers from University of Illinois at Chicago and Iowa State University cracked a forensic puzzle by exploring the fluid physics involved in a 2009 murder case. They found that backward blood spatter droplets can be entrained within a turbulent vortex ring of muzzle gases, potentially leaving shooter clothing bloodstain-free.
A new study found that nearly one-third of patients prescribed a direct oral anticoagulant were also taking aspirin without a clear reason, leading to an increased risk of bleeding events. The researchers emphasize the importance of consulting with doctors to determine if combination therapy is necessary for individual patients.
A recent study found that Flint adults suffered a range of adverse physical and mental health symptoms, including skin rashes, hair loss, depression, anxiety, and PTSD, linked to the water crisis. Black residents were particularly affected, with higher rates of reported symptoms.
Researchers at Medical University of Vienna improved liver transplant mortality prediction by adding laboratory parameters to the MELD score, which showed significant benefits in identifying high-risk patients. The study used vWF antigen and CRP levels to assess portal hypertension and inflammatory processes.
Researchers developed an ultrasensitive assay to measure cathepsin B in blood, detecting the biomarker for a range of disease states. This breakthrough aims to improve diagnosis and treatment strategies for conditions such as traumatic brain injury.
The US Preventive Services Task Force recommends against routine screening for vitamin D deficiency in healthy adults due to insufficient evidence. Individual requirements for vitamin D levels vary, making a one-size-fits-all approach challenging.
A study published in Nature Metabolism found that individuals who experience significant 'sugar dips' after eating tend to be hungrier and consume more calories throughout the day. Big dippers had a 9% increase in hunger and ate around 312 calories more than little dippers, potentially leading to weight gain over time.
A study published in the Journal of Endocrinology found an association between higher body weight and greater menstrual blood loss, potentially due to delayed womb lining repair. The research used a combined approach of human and mouse studies, suggesting obesity may contribute to heavier periods through increased inflammation.