Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
The study analyzed blood samples from bottlenose dolphins in the northern Gulf of Mexico, finding changes in gene expression related to immune response and oxidative stress. The results provide new insights into the health impacts of oil spills on marine life.
Researchers at RCSI found that patients with Long COVID syndrome have a blood-clotting imbalance due to high levels of von Willebrand Factor and low levels of ADAMTS13. The study suggests that this imbalance contributes to symptoms such as shortness of breath and fatigue.
Researchers developed a blood test that predicts poor outcomes in patients with traumatic brain injury (TBI), allowing clinicians to make decisions earlier on possible treatment. The test, which measures protein biomarkers GFAP and UCH-L1, showed high accuracy in predicting death and severe disability six months after injury.
A Rutgers scientist has developed a highly sensitive DNA test that can detect Lyme disease in horses, a condition that can cause long-term complications. The test, called genomic hybrid capture assay, was tested on a sick horse and successfully identified the pathogen, allowing for early diagnosis and treatment.
Researchers found that adults with low blood urate levels are more likely to have low skeletal muscle mass and strength. This association is also linked to a higher risk of early death, particularly due to weight loss and adverse body composition.
A 1g reduction in daily salt intake could prevent nearly 9 million cases of heart disease and stroke in China by 2030, saving 4 million lives. This is based on a modelling study that estimates the impact of reducing salt intake across the nation.
A West Virginia University study explores the link between pregnancy, sedentary behavior, and cardiovascular disease risk in women. The research aims to investigate whether physical activity can reduce or eliminate this accelerated risk development in women.
Researchers found that astrocytes can transfer their mitochondria to damaged neurons after a brain hemorrhage, stimulating the production of an enzyme that neutralizes free radicals. This treatment showed improved neurological recovery in mice, but not if the mitochondria were without the protective enzyme Mn-SOD.
A new analysis shows that combining two anti-platelet drugs can reduce the risk of graft failure after coronary artery bypass surgery, but also increase the risk of bleeding. The study found a significant reduction in graft failure rates with dual therapy, but more bleeding events requiring medical attention.
A pooled data analysis of 21 international clinical trials involving nearly 30,000 people found that salt substitutes lowered blood pressure and reduced the risk of heart attack, stroke, and early death. The benefits were consistent across different geography, age, sex, and health conditions.
Researchers at Weill Cornell Medicine found that disrupting circadian clocks leads to increased fat cell growth and insulin production. Stress and other factors can throw the body's 'clocks' out of rhythm, contributing to weight gain.
Researchers found that higher suPAR levels were associated with increased risk of blood clot formation in COVID-19 patients. Combining suPAR and D-dimer may improve predicting who is at high or low risk of blood clots, enabling targeted therapies to prevent critical outcomes.
Researchers discovered that vitamin K acts as an antioxidant, inhibiting ferroptotic cell death and identifying FSP1 as the warfarin-insensitive enzyme responsible. This finding has implications for treating Alzheimer's disease and acute organ injuries.
A new light-based sensor harnesses the light-guiding properties of spider silk to detect and measure small changes in the refractive index of a biological solution, including glucose and other types of sugar solutions. The sensor is practical, compact, biocompatible, cost-effective, and highly sensitive.
Research suggests that chemicals produced by gut microbes after eating red meat may contribute to cardiovascular disease. The study found a 22% higher risk of atherosclerotic cardiovascular disease associated with increased red meat consumption, which was partly attributed to elevated levels of TMAO and related metabolites in the blood.
A new study published in the Journal of the American Heart Association found that walking for exercise at a pace that induces leg pain or discomfort improves walking ability among people with peripheral artery disease. The study involved 264 participants who walked at home at either a comfortable pace or a pace that induced leg symptom...
A new study published in the Journal of the American Heart Association found that people with high genetic risk for stroke can reduce their risk by 30-45% by adopting a healthy cardiovascular lifestyle. The study followed 11,568 adults over 28 years and showed that modifying lifestyle risk factors can offset genetic risk.
Hospitalized COVID-19 patients with high blood viscosity have a 60% higher death rate than those with low blood viscosity. The study suggests that checking for blood viscosity early on could help determine the best treatment course and improve outcomes.
A UNC Charlotte-led team has invented a new biomolecular anticoagulant platform that holds promise as a revolutionary advancement over current blood thinners. The technology uses programmable RNA-DNA fibers to prevent blood clotting as needed, then be swiftly eliminated from the body.
Researchers found that CXCL9 levels were higher in pre-fracture blood samples of Chinese men with subsequent hip fractures, improving the prediction of osteoporotic hip fracture risk in men. In contrast, no association was found between CXCL10 and hip fracture risk in either gender.
A study found that individuals with a rare genetic variant common in people of East Asian descent are at higher risk of vessel reclog during or shortly after endovascular therapy for ischemic stroke. The researchers analyzed data from 277 East Asian adults who received the treatment between 2011 and 2021.
Researchers developed a heart-healthy diet based on traditional Chinese cuisine that reduced sodium levels by half, increased dietary fiber, and cut fat intake. The study found significant blood pressure reductions among participants, with potential implications for cardiovascular disease prevention.
A recent clinical trial found that low-dose benzbromarone was more effective in reducing blood urate levels in patients with renal urate underexcretion. The study showed that more participants in the benzbromarone group achieved the target blood urate level of < 6 mg/dL compared to those receiving febuxostat.
A study found that rates of serious complications associated with shoulder surgery are low, but one in 26 patients need further surgery within a year. The effectiveness of some shoulder procedures is doubtful at best, according to experts.
A new study by University of Missouri found that Black nursing home residents and those under 65 are significantly more likely to experience repeat hospital transfers. This phenomenon can be attributed to various factors including 'full-code' status regarding end-of-life care, comorbidities, and inadequate staffing. The study suggests ...
Researchers found that 67.7% of stroke patients with previously undiagnosed major risk factors had one underlying condition, with dyslipidaemia being the most common detected vascular risk factor. The study suggests that identifying and treating these conditions can help prevent future strokes.
Researchers from Dartmouth's Geisel School of Medicine found a significant rate of new TB infections among Tanzanian adolescents. The study used serial testing and identified transient, persistent, and irregular conversions between positive and negative IGRA test results.
Researchers used CT and MRI perfusion techniques to analyze 19 patients with successful free flap reconstruction and five with wound failure. The study found that both methods showed significant differences between the two patient groups. Early postoperative scans could help surgeons intervene earlier, potentially reducing hospital stays.
A new study reveals that inhaled fine particles can take a direct route from lungs to brain through blood circulation, potentially contributing to brain disorders. The particles were found to stay longer in the brain than in other organs, raising concerns about the long-term effects of air pollution on cognitive function.
A study by RCSI University of Medicine and Health Sciences has identified barriers and motivators to blood donation for people from ethnic minority groups in Ireland. Factors that motivate people from minority ethnic backgrounds to give blood include religious reasons and a desire to help others in their own communities.
A nationwide study in Sweden found that receiving red blood cells from female donors does not increase the risk of death in transfused patients. The study controlled for lower haemoglobin levels in women's blood and found no difference in survival rates between male and female donors.
Research linked to PFAS exposure in middle-aged women reveals a stronger association between combined exposure and blood pressure risk. The study suggests strategies to limit PFAS use may help reduce high blood pressure incidence in midlife women.
A pooled data analysis reveals that 14.5% of the global population may have had tick-borne Lyme disease, with higher prevalence in men aged 50+, rural areas, and Central and Western Europe. The study suggests that improvements to antibody detection methods could enhance public health response policies.
Researchers found that increasing serotonin levels in mosquito blood reduces their flight speed and motivation to seek second blood meals, making them less efficient vectors of malaria parasites. This discovery provides a promising new avenue for insect-targeted interventions to prevent malaria transmission.
A comprehensive register study at the University of Gothenburg shows individuals with diabetes have a substantially increased risk of left-sided heart valve disease. Lowering blood pressure and reducing other risk factors may even reduce this risk more than current treatment targets suggest.
A new review analyzes the efficacy of current non-invasive methods for assessing non-alcoholic fatty liver disease (NAFLD) and associated conditions. Blood-based biomarker tests and imaging methods are explored, with some showing promise in early diagnosis and staging liver disorders.
Researchers validated a liquid biopsy test as a better predictor of immunotherapy response in lung cancer patients compared to traditional tumor biopsies. The test measures the PD-L1 biomarker in blood, showing improved accuracy in predicting treatment outcomes and survival.
Researchers found that the effectiveness of exercise depends on the time of day, with morning exercise reducing belly fat and blood pressure in women, while evening exercise increasing muscular performance. For men, evening exercise lowers blood pressure, burns more fat, and improves heart disease risk.
A new systematic review and meta-analysis published in The BMJ provides a comprehensive understanding of the adverse outcomes associated with gestational diabetes mellitus during pregnancy. The study found that women with gestational diabetes had increased odds of caesarean section, preterm delivery, and infant complications.
Researchers identified a blood biomarker that predicts severe Crohn's disease and is detectable up to seven years prior to diagnosis. The biomarker neutralizes protective effects of a cytokine, leading to intestinal damage and weakening the immune system.
The Mount Sinai Hospital will recruit eight postdoctoral trainees for a five-year fellowship program in emergency care research. The program aims to investigate complex medical questions and lead to studies transforming patient care.
Researchers developed a method combining low-power lasers with ultrasound to safely and efficiently remove arterial plaque. The technique reduces the risk of complications and improves the efficiency of plaque removal compared to traditional methods.
A large-scale study has found that men with prostate cancer have a 50% higher risk of developing serious and potentially fatal blood clots during the five years after their diagnosis. This increased risk is significant because venous thromboembolism (VTE) is a leading cause of death among people with cancer.
A new review highlights the risks of fatty liver disease caused by metabolic dysfunction, characterized by fat accumulation in liver cells and oxidative stress. The progression of the disease can lead to inflammation, fibrosis, and cirrhosis with a high risk of hepatocellular carcinoma.
A new study published in the American Journal of Clinical Nutrition finds that choline supplementation increases DHA bioavailability during pregnancy. Choline helps the body more efficiently use omega-3 fatty acid DHA, which is essential for fetal brain, cognition and vision development.
A new study published in Open Heart found that patients with asymptomatic severe aortic stenosis benefit from early valve replacement surgery to prevent irreversible heart muscle damage. The research showed that timing of surgery is crucial in reducing mortality and hospitalization rates.
A study found that high blood adenosine levels at 15 days of life correlated with white matter lesions and brain injury in very low birth weight premature infants. Adenosine may play a role in oligodendrocyte maturation and neuronal development, suggesting its potential as a biomarker for complications of prematurity.
Women's metabolism alters during menopause due to changes in sex hormone levels. Metabolite profiles show increased lipid and cholesterol levels, especially triglycerides and LDL particles, which can lead to atherosclerosis.
A new study from Tel Aviv University finds that women aged 55 and over who snore are at significant risk for sleep apnea, which can be fatal. The researchers warn that the phenomenon often occurs during sleep, causing women to be unaware of their condition.
A meta-analysis published in the European Journal of Clinical Nutrition found that diets containing red meat did not impact glycemic and insulinemic risk factors for type 2 diabetes. The study suggests that more research is needed to fully understand the relationship between red meat consumption and the development of type 2 diabetes.
Researchers assessed metabolites in African savanna elephants for the first time, finding little variation among six healthy adults on the same diet. The study establishes a technique to accurately capture metabolites and provides insights into metabolism and health relationships in these endangered animals.
Scientists use advanced measurement methods to study carotid artery stenosis, discovering significant gaps between their findings and clinical methods. They propose improvements for surgical treatment technology and future medical devices.
A study funded by NIH found that women who had high blood pressure during pregnancy had a 63% increased risk for developing cardiovascular disease later in life. Early screening and monitoring in targeted areas can help delay or prevent future cardiovascular events among these women.
Researchers have identified potential biomarkers in lupus nephritis through large-scale protein analysis, which may replace invasive tests. The study's findings could lead to more accurate diagnosis and treatment of the disease.
A team of researchers, led by UNC's Stephan Moll, monitored astronauts on the International Space Station for signs of blood clots. The study found that slowed blood flow and abnormal vessel size may predispose astronauts to blood clots, highlighting the need for further research.
Research at Mount Sinai Hospital found a significant difference in the prevalence of occult hypoxemia among Black, Hispanic, and White patients undergoing anesthesia. The study showed that Black and Hispanic patients experienced higher rates of unrecognized low oxygen levels despite normal pulse oximeter values.
A study in rural Malawi found high mortality rates for children admitted to hospital with low blood sugar or oxygen levels. The findings suggest that earlier identification and prompt care-seeking could help reduce the risk of death, emphasizing the need for better clinical management of severely ill children.
Researchers developed a disposable electrochemical sensor using graphite-based molecularly imprinted polymers to detect theophylline levels. The sensor can identify low concentrations of theophylline (2.5 μg/mL) in whole blood within 3 seconds, enabling real-time monitoring and potential overdose prevention.
A study led by Richard Isaacson found that individualized, multi-domain interventions improved cognition and reduced Alzheimer's risk in both men and women. Women demonstrated greater improvements in certain risk scores and biomarkers compared to men.
A new study from Boston Medical Center found that COVID-19 infection during pregnancy is associated with elevated inflammatory markers in infants, potentially impacting growth and brain development. Researchers emphasize the importance of COVID-19 vaccinations for pregnant women to avoid long-term adverse consequences for their infant.