Articles tagged with Blood
A recent clinical trial found that low-dose benzbromarone was more effective in reducing blood urate levels in patients with renal urate underexcretion. The study showed that more participants in the benzbromarone group achieved the target blood urate level of < 6 mg/dL compared to those receiving febuxostat.
A study found that rates of serious complications associated with shoulder surgery are low, but one in 26 patients need further surgery within a year. The effectiveness of some shoulder procedures is doubtful at best, according to experts.
A new study by University of Missouri found that Black nursing home residents and those under 65 are significantly more likely to experience repeat hospital transfers. This phenomenon can be attributed to various factors including 'full-code' status regarding end-of-life care, comorbidities, and inadequate staffing. The study suggests ...
Researchers found that 67.7% of stroke patients with previously undiagnosed major risk factors had one underlying condition, with dyslipidaemia being the most common detected vascular risk factor. The study suggests that identifying and treating these conditions can help prevent future strokes.
Researchers from Dartmouth's Geisel School of Medicine found a significant rate of new TB infections among Tanzanian adolescents. The study used serial testing and identified transient, persistent, and irregular conversions between positive and negative IGRA test results.
Researchers used CT and MRI perfusion techniques to analyze 19 patients with successful free flap reconstruction and five with wound failure. The study found that both methods showed significant differences between the two patient groups. Early postoperative scans could help surgeons intervene earlier, potentially reducing hospital stays.
A new study reveals that inhaled fine particles can take a direct route from lungs to brain through blood circulation, potentially contributing to brain disorders. The particles were found to stay longer in the brain than in other organs, raising concerns about the long-term effects of air pollution on cognitive function.
A study by RCSI University of Medicine and Health Sciences has identified barriers and motivators to blood donation for people from ethnic minority groups in Ireland. Factors that motivate people from minority ethnic backgrounds to give blood include religious reasons and a desire to help others in their own communities.
Researchers found that increasing serotonin levels in mosquito blood reduces their flight speed and motivation to seek second blood meals, making them less efficient vectors of malaria parasites. This discovery provides a promising new avenue for insect-targeted interventions to prevent malaria transmission.
A nationwide study in Sweden found that receiving red blood cells from female donors does not increase the risk of death in transfused patients. The study controlled for lower haemoglobin levels in women's blood and found no difference in survival rates between male and female donors.
Research linked to PFAS exposure in middle-aged women reveals a stronger association between combined exposure and blood pressure risk. The study suggests strategies to limit PFAS use may help reduce high blood pressure incidence in midlife women.
A pooled data analysis reveals that 14.5% of the global population may have had tick-borne Lyme disease, with higher prevalence in men aged 50+, rural areas, and Central and Western Europe. The study suggests that improvements to antibody detection methods could enhance public health response policies.
A comprehensive register study at the University of Gothenburg shows individuals with diabetes have a substantially increased risk of left-sided heart valve disease. Lowering blood pressure and reducing other risk factors may even reduce this risk more than current treatment targets suggest.
Researchers validated a liquid biopsy test as a better predictor of immunotherapy response in lung cancer patients compared to traditional tumor biopsies. The test measures the PD-L1 biomarker in blood, showing improved accuracy in predicting treatment outcomes and survival.
A new review analyzes the efficacy of current non-invasive methods for assessing non-alcoholic fatty liver disease (NAFLD) and associated conditions. Blood-based biomarker tests and imaging methods are explored, with some showing promise in early diagnosis and staging liver disorders.
Researchers found that the effectiveness of exercise depends on the time of day, with morning exercise reducing belly fat and blood pressure in women, while evening exercise increasing muscular performance. For men, evening exercise lowers blood pressure, burns more fat, and improves heart disease risk.
A new systematic review and meta-analysis published in The BMJ provides a comprehensive understanding of the adverse outcomes associated with gestational diabetes mellitus during pregnancy. The study found that women with gestational diabetes had increased odds of caesarean section, preterm delivery, and infant complications.
Researchers developed a method combining low-power lasers with ultrasound to safely and efficiently remove arterial plaque. The technique reduces the risk of complications and improves the efficiency of plaque removal compared to traditional methods.
Researchers identified a blood biomarker that predicts severe Crohn's disease and is detectable up to seven years prior to diagnosis. The biomarker neutralizes protective effects of a cytokine, leading to intestinal damage and weakening the immune system.
The Mount Sinai Hospital will recruit eight postdoctoral trainees for a five-year fellowship program in emergency care research. The program aims to investigate complex medical questions and lead to studies transforming patient care.
A large-scale study has found that men with prostate cancer have a 50% higher risk of developing serious and potentially fatal blood clots during the five years after their diagnosis. This increased risk is significant because venous thromboembolism (VTE) is a leading cause of death among people with cancer.
A new review highlights the risks of fatty liver disease caused by metabolic dysfunction, characterized by fat accumulation in liver cells and oxidative stress. The progression of the disease can lead to inflammation, fibrosis, and cirrhosis with a high risk of hepatocellular carcinoma.
A new study published in the American Journal of Clinical Nutrition finds that choline supplementation increases DHA bioavailability during pregnancy. Choline helps the body more efficiently use omega-3 fatty acid DHA, which is essential for fetal brain, cognition and vision development.
A new study published in Open Heart found that patients with asymptomatic severe aortic stenosis benefit from early valve replacement surgery to prevent irreversible heart muscle damage. The research showed that timing of surgery is crucial in reducing mortality and hospitalization rates.
A study found that high blood adenosine levels at 15 days of life correlated with white matter lesions and brain injury in very low birth weight premature infants. Adenosine may play a role in oligodendrocyte maturation and neuronal development, suggesting its potential as a biomarker for complications of prematurity.
Women's metabolism alters during menopause due to changes in sex hormone levels. Metabolite profiles show increased lipid and cholesterol levels, especially triglycerides and LDL particles, which can lead to atherosclerosis.
A new study from Tel Aviv University finds that women aged 55 and over who snore are at significant risk for sleep apnea, which can be fatal. The researchers warn that the phenomenon often occurs during sleep, causing women to be unaware of their condition.
A meta-analysis published in the European Journal of Clinical Nutrition found that diets containing red meat did not impact glycemic and insulinemic risk factors for type 2 diabetes. The study suggests that more research is needed to fully understand the relationship between red meat consumption and the development of type 2 diabetes.
Researchers assessed metabolites in African savanna elephants for the first time, finding little variation among six healthy adults on the same diet. The study establishes a technique to accurately capture metabolites and provides insights into metabolism and health relationships in these endangered animals.
Scientists use advanced measurement methods to study carotid artery stenosis, discovering significant gaps between their findings and clinical methods. They propose improvements for surgical treatment technology and future medical devices.
A study funded by NIH found that women who had high blood pressure during pregnancy had a 63% increased risk for developing cardiovascular disease later in life. Early screening and monitoring in targeted areas can help delay or prevent future cardiovascular events among these women.
Researchers have identified potential biomarkers in lupus nephritis through large-scale protein analysis, which may replace invasive tests. The study's findings could lead to more accurate diagnosis and treatment of the disease.
A team of researchers, led by UNC's Stephan Moll, monitored astronauts on the International Space Station for signs of blood clots. The study found that slowed blood flow and abnormal vessel size may predispose astronauts to blood clots, highlighting the need for further research.
Research at Mount Sinai Hospital found a significant difference in the prevalence of occult hypoxemia among Black, Hispanic, and White patients undergoing anesthesia. The study showed that Black and Hispanic patients experienced higher rates of unrecognized low oxygen levels despite normal pulse oximeter values.
A study in rural Malawi found high mortality rates for children admitted to hospital with low blood sugar or oxygen levels. The findings suggest that earlier identification and prompt care-seeking could help reduce the risk of death, emphasizing the need for better clinical management of severely ill children.
Researchers developed a disposable electrochemical sensor using graphite-based molecularly imprinted polymers to detect theophylline levels. The sensor can identify low concentrations of theophylline (2.5 μg/mL) in whole blood within 3 seconds, enabling real-time monitoring and potential overdose prevention.
A study led by Richard Isaacson found that individualized, multi-domain interventions improved cognition and reduced Alzheimer's risk in both men and women. Women demonstrated greater improvements in certain risk scores and biomarkers compared to men.
A new study from Boston Medical Center found that COVID-19 infection during pregnancy is associated with elevated inflammatory markers in infants, potentially impacting growth and brain development. Researchers emphasize the importance of COVID-19 vaccinations for pregnant women to avoid long-term adverse consequences for their infant.
A new study found that three experimental Alzheimer's blood tests perform differently in Black individuals compared to white individuals, putting Black patients at risk of misdiagnosis and inappropriate medical care. The PrecivityAD test was equally effective across racial groups.
A study of 8,900 patients in New York State hospitals revealed racial and ethnic disparities in pain treatment for obstetric patients. Obstetric patients in minority groups were less likely to receive an epidural blood patch (EBP) for postdural puncture headache during delivery hospitalization.
A new study found that following a Mediterranean-style diet can lower the risk of preeclampsia by at least 20% in pregnant women. The research surveyed over 8,000 women and found that racial differences in rates of preeclampsia were more related to socioeconomic factors than genetic or biological ones.
Researchers developed an automated system called Clinical Antimicrobials Susceptibility Test Ramanometry (CAST-R) to identify the best antibiotics for treating acute blood infections. The system uses Raman microspectroscopy and machine learning to achieve rapid and accurate results, outperforming conventional methods in just three hours.
A new study published in the Chinese Medical Journal assessed mortality risk in middle-aged and older Chinese individuals with multiple diseases. The study identified four multimorbidity patterns, with cardiometabolic being the most common, and found that individuals with these patterns had a significantly increased mortality risk.
Researchers discovered a link between non-O blood types and an increased risk of developing venous thromboembolism in cancer patients. This finding suggests that blood typing may serve as another important predictive measure for identifying individuals at high risk.
Researchers developed innovative smart sensors to test new vaccines, revealing significant discrepancies between subjective self-reports and objective measurements. The study found that side effects escalate over the first 48 hours and then stabilize, with parameters returning to pre-vaccination levels.
Scientists have developed a method using DNA from blood meals of blood-sucking leeches to survey vertebrate species in large areas. The study, led by Harvard researchers, identified 86 vertebrate species in the reserve, including near-threatened and threatened species.
A study by University of Gothenburg researchers has identified two biomarkers that can distinguish between patients with subcortical small-vessel disease, Alzheimer's disease, and mixed dementia. The discovery opens up new possibilities for diagnosis, treatment, and medication development.
A study of patients treated with edoxaban and dual antiplatelet therapy (DAPT) after TAVR found that edoxaban reduced subclinical leaflet thrombosis, but did not affect stroke risk. Rates of death, stroke, and cognitive decline were similar in both groups.
A randomized clinical trial comparing FFR-guided and IVUS-guided PCI found similar outcomes for patients with intermediate coronary artery stenosis. Patients evaluated by FFR underwent fewer stents but had similar rates of adverse events and improved quality of life.
The study found significant improvements in blood flow through the heart and quality of life at one year, with all 36 patients achieving a reduction in tricuspid regurgitation severity. Longer follow-up is needed to determine how well the device continues to perform.
Researchers found a significant decline in in-hospital mortality and secondary endpoints for STEMI patients with COVID-19 in 2021 compared to 2020. Vaccination status showed zero hospital deaths among vaccinated patients, while unvaccinated patients experienced high death rates.
Researchers found significant and sustained improvements in left ventricular outflow tract gradients, health status, symptoms, and exercise capacity among patients taking mavacamten. The drug appears to be safe and well-tolerated long-term with no new adverse events reported.
The study found that patiromer significantly lowers blood potassium levels in patients taking RAASi medications for heart failure. The results suggest that patiromer can be used to control excess potassium buildup in the blood, which is a common side effect of RAASi therapy.
A new study found that customized digital alerts via an electronic health record system significantly increased the number of guideline-directed medications prescribed for heart failure patients. The alerts improved medication use by over a quarter of patients, translating to one medication addition per every 14 alerts received.
Researchers found that SLN360, an experimental siRNA therapy, significantly reduced blood levels of lipoprotein(a), a lesser-known driver of heart disease risk. Participants who received higher doses saw their lipoprotein(a) levels drop by up to 98% and remained lower even after five months.
A post-hoc subgroup analysis of the AFIRE trial found that reduced kidney function significantly influences bleeding events during antithrombotic therapy. Patients with healthy kidney function have a decreased risk of bleeding over time, while those with reduced kidney function remain at high risk.
Researchers have identified a blood biomarker called glial fibrillary acidic protein (GFAP) that may uniquely aid prediction of dementia in Mexican Americans. The study analyzed 745 participants over four years, finding that higher levels of GFAP predicted increased risk of developing dementia.
A study found that 42% of TikTok videos on high blood pressure focused on alternative medicine, while only 5% mentioned exercise. Most creators were not healthcare professionals, highlighting the need for more emphasis on credible sources.
A study found that many nursing home residents continue to receive insulin and other medications despite blood test results suggesting tight control. Only 27% of overtreated and 19% of potentially overtreated residents had their medications adjusted within 2 weeks.
A study suggests that smartwatch heart rate measurement algorithms are less effective in people with darker skin tones due to increased melanin absorption. Researchers emphasize the need for diverse population inclusion and explore alternative light wavelengths for more accurate readings.