Articles tagged with Blood
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that 'The Secret', a centuries-old folk medicine remedy, does not prevent bleeding after invasive coronary procedures. However, the study suggests that it may have therapeutic value due to its placebo effect, potentially providing stress relief for its believers.
Researchers at Kyoto University have discovered a vital role of two proteins, ABCA1 and Aster-A, in maintaining the asymmetric distribution of cholesterol within cells. This process allows for selective control over substances entering and leaving cells.
A study by Osaka University tracked the survival of antibody-producing plasma cells, finding that most die shortly after immune response, but a small population can survive for months or years. The researchers identified molecular markers distinguishing these long-lived plasma cells from short-lived ones.
Researchers found that simultaneously targeting two signalling switches can severely inhibit tumour angiogenesis, cancer growth and metastasis in multiple models of cancer. This approach has the potential to restrict a cancer's ability to escape therapy by rapidly destroying the VEGF receptor when both receptors are targeted.
A new study identifies anti-Müllerian hormone (AMH) as a key factor in regulating cholesterol levels during the menopause transition. High AMH levels are associated with lower HDL-C, or good cholesterol, which may indicate cardiovascular risk despite its traditionally protective effects.
A study found that antibodies to common antibiotic gentamicin are associated with an increased risk of progression to type 1 diabetes in children already genetically at risk. The researchers also identified an association between the FUT2 gene and the production of these antibodies, which may be compounding risks for type 1 diabetes.
A new, non-invasive malaria detection tool developed by a University of Queensland-led team can quickly identify entire villages or towns suffering from the disease. The device uses infrared-light and is chemical-free, needle-free, and detects malaria through the skin.
A study of 510 children with chronic kidney disease found that declining hemoglobin levels were associated with significant growth impairment even when above guideline-targeted levels. Lower hemoglobin values are linked to poorer growth, independent of kidney function and age.
A new diagnostic pathway for prostate cancer reduces the number of harmless tumors found during screening, halving the risk of overdiagnosis. This strategy involves using MRI to guide targeted tissue sampling, reducing the need for unnecessary biopsies and associated complications.
A large study found that most Canadian children and adults younger than 60 had been exposed to SARS-CoV-2 through a combination of vaccination and infection. The study, conducted in British Columbia, shows a dramatic change in the proportion of the population with antibodies over the first 2.5 years of the pandemic.
Researchers developed an efficient engineered pathogen capture method to quickly identify infectious microbes in tiny blood samples. This advanced technology could significantly improve clinical outcomes for children with bloodstream infections and sepsis.
A study of over 1000 Australian adults found that people with trouble sleeping were more likely to have indicators of poor cardiometabolic health, including inflammatory markers, cholesterol, and body weight. Prioritizing a good night's sleep is crucial for maintaining good health, according to researcher Dr Lisa Matricciani.
Researchers found shared genetic factors that contribute to severe COVID-19 risk and blood analyte levels. High triglyceride levels were strongly linked to increased risk of severe disease, supporting the use of lipid-lowering drugs against severe COVID-19.
Scientists at Medical College of Georgia discover a new target to intervene in coronary artery disease, the most common type of heart disease. The target is ATIC, a gene essential for purine production, which increases in response to arterial disease.
A new study suggests that blood tests can predict survival odds for patients with metastatic cancer by analyzing the proportion of tumor DNA in the bloodstream. Patients with higher levels of tumor DNA in their bloodstreams were found to have poorer survival rates across all cancer types studied.
A study found that individuals with blood group Rh(D) have a higher risk of contracting parvovirus, which causes fifth disease. The study screened over 160,000 blood donors in Germany and found all infected persons belonged to the Rh(D) blood group.
A new microfluidic multiplexed chip uses CRISPR technology to detect SARS-CoV-2 and monitor antibiotic levels, offering a rapid and sensitive solution for managing COVID-19 patients. The test omits nucleic acid amplification and can be easily adapted to new virus mutations.
A trial found that extending anti-clotting treatment after a blood clot in the lower leg reduced further clot risk up to two years. Rivaroxaban administered for three months effectively and safely reduced venous thromboembolism compared to six weeks of treatment.
Researchers found that individuals with persistent asthma have higher levels of inflammation and artery plaque, which may increase heart attack or stroke risk. The study also highlights the importance of addressing risk factors for cardiovascular disease in people with persistent asthma.
Research published in General Psychiatry finds a significant causal relationship between diastolic blood pressure and neuroticism, while systolic blood pressure has no association. Controlling high diastolic blood pressure may help reduce neurotic behaviors, anxiety, and cardiovascular diseases.
A new study from Mount Sinai Hospital finds a strong association between age-related macular degeneration and severe forms of heart disease, including heart failure, heart attacks, and stroke. The study highlights the importance of increased screening for eye disorders to diagnose undetected heart disease.
A study by Leiden University Medical Center found six proteins in blood samples that were altered one to two years before a breast cancer diagnosis. The researchers believe these proteins could be used to develop a blood test for early detection of breast cancer in high-risk women.
A new injectable hydrogel has been developed with enhanced shear-thinning properties, improved cellular biocompatibility, and significantly reduced clotting times. The biomaterial was created by adding sodium phytate to a gelatin-based compound, promoting even greater cohesion and triggering the initiation of blood coagulation.
A large South Korean cohort study found a five-fold increased risk of chronic kidney disease (CKD) for adults with persistent hematuria. Associations were stronger in men compared to women.
A study of 2,400 women found nearly a quarter developed high blood pressure more than six weeks after delivery. The research suggests monitoring during this period could mitigate severe cardiovascular complications.
A randomized controlled trial found that both total ankle replacement and ankle fusion improve quality of life and have similar clinical scores in patients with end-stage ankle osteoarthritis. However, TAR is associated with greater wound-healing complications and nerve injuries, while AF is linked to more blood clots and nonunion of t...
Researchers have created a chemical tag that can be added to drugs, allowing them to enter blood circulation via the intestines. The tag, called EPP6, is a neutral peptide that can deliver drugs orally, potentially replacing injections for diabetes and cancer patients.
A Rice University bioengineer has developed a noninvasive technology to measure gene expression in deep tissues, particularly in the brain. This innovation could improve the monitoring of gene therapy treating neurodegenerative disorders such as epilepsy, ALS, and Huntington's disease.
A recent study found that restoring blood flow to the legs through bypass surgery or stent placement reduced pain and improved quality of life for people with peripheral artery disease (PAD). The Best Endovascular versus Best Surgical Therapy for Patients with Chronic Limb Threatening Ischemia Trial enrolled 1,830 participants and foun...
A clinical trial found that early use of ECMO devices did not improve outcomes for adults with rapidly deteriorating or severe cardiogenic shock. Participants who received immediate ECMO therapy showed similar clinical outcomes as those receiving early conservative therapy, including treatment with inotropes and vasopressors.
Researchers found that two common diuretics, chlorthalidone and hydrochlorothiazide, had no difference in cardiovascular outcomes among study participants. However, those taking chlorthalidone showed a reduced risk of heart disease and death by an average of 27% among patients with a history of heart attack or stroke.
A customized mindfulness program that incorporates skills like attention control and self-awareness has been shown to lead to lower systolic blood pressure measures in participants. The intervention, which also focuses on health behavior change, is promising as a novel way to improve blood pressure control.
A new study has shown that bivalirudin is a safer and more effective anticoagulant than heparin for treating heart attack patients. The trial found that bivalirudin significantly reduced death, major bleeding, and thrombosis in patients undergoing percutaneous coronary intervention.
A study published in the American Heart Association found that six common dietary supplements did not lower LDL cholesterol levels when compared to a low-dose statin medication or placebo. The research suggests that these supplements are unlikely to offer meaningful impact on cholesterol levels, and a heart-healthy lifestyle is still t...
Researchers describe how oxygen levels in the blood are detected using specialized mitochondria in glomus cells. A study on genetically modified mice reveals that a functional electron transport chain is crucial for this process, which has implications for respiratory depression and diseases.
Researchers have discovered a new role for VWF in regulating immune responses at sites of blood vessel injury, leading to potential treatment options for inflammatory and blood clotting disorders. The study found that VWF plays a key role in repairing damaged blood vessels, which could help prevent heavy bleeding and blood clots.
A new metric estimates cumulative exposure to PFAS chemicals, enabling comparisons across studies and applications. The calculator takes into account patterns of exposure to multiple chemicals, providing a robust tool for biomonitoring and disease assessment.
A study of over 1.3 million young Asian American adults hospitalized for atrial fibrillation found a significant increase in obesity and other modifiable cardiovascular disease risk factors. Young adults with at least one cardiovascular risk factor were almost three times more likely to be hospitalized for atrial fibrillation.
A study of 9,303 US adults found that people with cardiovascular disease were less likely to use wearable devices, highlighting disparities in access and use. The research emphasizes the need to ensure equitable access to wearables to benefit high-risk populations.
A recent investigation by The BMJ reveals dozens of UK companies offering private blood tests with misleading claims, contradicting official medical guidance and potentially harming individuals. Experts argue for regulation to protect consumers and prevent unnecessary costs for the NHS.
A Tel Aviv University study shows that pressure chamber therapy can improve social skills and reduce neuroinflammation in the autistic brain. The treatment, which involves high-pressure chambers with oxygen enrichment, was found to increase blood and oxygen supply to the brain, leading to improved brain function and social behavior.
A new protein called TANGO2 helps mobilize heme from sites of synthesis and storage for use in cells. Understanding its role may lead to therapeutic strategies for diseases associated with heme dysregulation.
Researchers from McGill University developed a medical adhesive inspired by flatworms that uses suction to absorb blood and promote blood coagulation. The adhesive can be removed without causing re-bleeding, making it a potential replacement for wound sutures or delivering drugs.
A UC Riverside-led study found that acute THS exposure initiates mechanisms of inflammatory skin disease and elevates urinary biomarkers of oxidative harm. The researchers discovered elevated molecular biomarkers in blood associated with early-stage activation of contact dermatitis, psoriasis, and other skin conditions.
Researchers found that higher levels of cell-free DNA in the blood are associated with increased cognitive decline and worsening frailty over an eight-year period. The study suggests that a simple blood test could detect risk of Alzheimer's disease and other forms of cognitive decline, potentially leading to early interventions.
Aneurysms occur when blood vessel thins and expands, leading to increased stress on walls and rising rupture probability. The new model uses computed tomography scans to reconstruct geometry and blood flow patterns.
Researchers analyzing over 3,000 blood samples from Alzheimer's patients and healthy individuals to identify reliable biomarkers. They investigate how well blood tests can diagnose Alzheimer's disease and predict its progression.
Researchers have developed a novel, non-invasive way to measure blood flow to the brains of newborn children at the bedside. This method uses real-time ultrasound color flow technique and 3D sampling to capture flow in a completely painless and safe manner.
Researchers at Hokkaido University have developed a biosensing technology to detect amyloid β build-up in the brain from biomarkers in blood samples. The Digital ICA TM technology can detect Aβ-binding exosomes in mice, increasing with age and disease progression.
Researchers have used single-cell sequencing to uncover novel gene expression patterns in injured kidney cells, providing new avenues for biomarker discovery and treatment. The studies reveal that epithelial cells of all tubule segments are involved in the injury processes, with distinct molecular patterns across patients.
Researchers developed an AI algorithm to assess retinal vasculature, predicting cardiovascular disease and death. The model captured half to two-thirds of circulatory disease deaths in those most at risk, outperforming traditional risk frameworks.
Researchers at the University of Pittsburgh discovered that a cellular channel outside the kidneys plays a crucial role in maintaining healthy blood pressure levels. The study found that subtle mutations in this channel can influence blood pressure, providing a potential new target for existing medications.
A new research paper has demonstrated that psychological factors, such as feeling unhappy or being lonely, add up to 1.65 years to one's biological age, significantly impacting overall health and longevity.
A USC-led team has found indications for an early breast cancer detection method using high-definition liquid biopsies. The test detected multiple cancer biomarkers, including 'oncosomes,' in the blood samples of most early-stage breast cancer patients.
Researchers discovered that macrophages eliminate stressed stem cells with high levels of reactive oxygen species, while healthy cells are amplified. The study found that a specific marker, calreticulin, acts as an 'eat me' signal for stressed cells.
A study published in Science finds that gut rotation is regulated by two waves of Pitx2 expression, triggered by mechanical cues and a latent TGF-beta sensor. This discovery sheds light on the mechanisms of organ formation and has implications for understanding birth defects such as intestinal malrotation.
A new study proposes reducing toxic proteins in the blood as a potential therapy for Alzheimer's disease. By doing so, it aims to improve memory and learning capacity, as well as correct cognitive impairments. The next step is to test this treatment at a clinical level.
Women with a history of gestational diabetes are at substantially higher risk of cardiovascular and cerebrovascular diseases, including coronary artery disease, heart attack, and stroke. Continuous monitoring is crucial to mitigate these risks.
A randomized clinical trial found that protein restriction diets can lead to weight loss, improved blood sugar and lipid levels, and controlled blood pressure. The study involved 21 patients with metabolic syndrome, who were given either a calorie or protein restriction diet for 27 days.
Research at Kumamoto University reveals that fetal liver blood cells are stem cell-independent, contrary to the long-held view that HSCs are essential for their production. The study provides new insights into the origin of HSCs and suggests a reconsideration of their role in embryo formation.