Articles tagged with Blood
A Tel Aviv University study shows that pressure chamber therapy can improve social skills and reduce neuroinflammation in the autistic brain. The treatment, which involves high-pressure chambers with oxygen enrichment, was found to increase blood and oxygen supply to the brain, leading to improved brain function and social behavior.
A recent investigation by The BMJ reveals dozens of UK companies offering private blood tests with misleading claims, contradicting official medical guidance and potentially harming individuals. Experts argue for regulation to protect consumers and prevent unnecessary costs for the NHS.
A new protein called TANGO2 helps mobilize heme from sites of synthesis and storage for use in cells. Understanding its role may lead to therapeutic strategies for diseases associated with heme dysregulation.
Researchers from McGill University developed a medical adhesive inspired by flatworms that uses suction to absorb blood and promote blood coagulation. The adhesive can be removed without causing re-bleeding, making it a potential replacement for wound sutures or delivering drugs.
Researchers found that higher levels of cell-free DNA in the blood are associated with increased cognitive decline and worsening frailty over an eight-year period. The study suggests that a simple blood test could detect risk of Alzheimer's disease and other forms of cognitive decline, potentially leading to early interventions.
Aneurysms occur when blood vessel thins and expands, leading to increased stress on walls and rising rupture probability. The new model uses computed tomography scans to reconstruct geometry and blood flow patterns.
A UC Riverside-led study found that acute THS exposure initiates mechanisms of inflammatory skin disease and elevates urinary biomarkers of oxidative harm. The researchers discovered elevated molecular biomarkers in blood associated with early-stage activation of contact dermatitis, psoriasis, and other skin conditions.
Researchers have developed a novel, non-invasive way to measure blood flow to the brains of newborn children at the bedside. This method uses real-time ultrasound color flow technique and 3D sampling to capture flow in a completely painless and safe manner.
Researchers analyzing over 3,000 blood samples from Alzheimer's patients and healthy individuals to identify reliable biomarkers. They investigate how well blood tests can diagnose Alzheimer's disease and predict its progression.
Researchers at Hokkaido University have developed a biosensing technology to detect amyloid β build-up in the brain from biomarkers in blood samples. The Digital ICA TM technology can detect Aβ-binding exosomes in mice, increasing with age and disease progression.
Researchers have used single-cell sequencing to uncover novel gene expression patterns in injured kidney cells, providing new avenues for biomarker discovery and treatment. The studies reveal that epithelial cells of all tubule segments are involved in the injury processes, with distinct molecular patterns across patients.
Researchers at the University of Pittsburgh discovered that a cellular channel outside the kidneys plays a crucial role in maintaining healthy blood pressure levels. The study found that subtle mutations in this channel can influence blood pressure, providing a potential new target for existing medications.
Researchers developed an AI algorithm to assess retinal vasculature, predicting cardiovascular disease and death. The model captured half to two-thirds of circulatory disease deaths in those most at risk, outperforming traditional risk frameworks.
A new research paper has demonstrated that psychological factors, such as feeling unhappy or being lonely, add up to 1.65 years to one's biological age, significantly impacting overall health and longevity.
A USC-led team has found indications for an early breast cancer detection method using high-definition liquid biopsies. The test detected multiple cancer biomarkers, including 'oncosomes,' in the blood samples of most early-stage breast cancer patients.
Researchers discovered that macrophages eliminate stressed stem cells with high levels of reactive oxygen species, while healthy cells are amplified. The study found that a specific marker, calreticulin, acts as an 'eat me' signal for stressed cells.
A new study proposes reducing toxic proteins in the blood as a potential therapy for Alzheimer's disease. By doing so, it aims to improve memory and learning capacity, as well as correct cognitive impairments. The next step is to test this treatment at a clinical level.
A study published in Science finds that gut rotation is regulated by two waves of Pitx2 expression, triggered by mechanical cues and a latent TGF-beta sensor. This discovery sheds light on the mechanisms of organ formation and has implications for understanding birth defects such as intestinal malrotation.
Women with a history of gestational diabetes are at substantially higher risk of cardiovascular and cerebrovascular diseases, including coronary artery disease, heart attack, and stroke. Continuous monitoring is crucial to mitigate these risks.
Research at Kumamoto University reveals that fetal liver blood cells are stem cell-independent, contrary to the long-held view that HSCs are essential for their production. The study provides new insights into the origin of HSCs and suggests a reconsideration of their role in embryo formation.
A randomized clinical trial found that protein restriction diets can lead to weight loss, improved blood sugar and lipid levels, and controlled blood pressure. The study involved 21 patients with metabolic syndrome, who were given either a calorie or protein restriction diet for 27 days.
Researchers analyzed over 6,700 patients treated for blood clots and irregular heart rhythms. Stopping aspirin significantly reduced bleeding complications by 32.3% and prevented one major bleeding event per every 1,000 patients who stopped taking aspirin.
Researchers from Temple University Health System developed a device that significantly reduces blood clot size in pulmonary arteries, leading to improved heart function and shorter treatment duration. The breakthrough is based on data collected in the NIH-sponsored RESCUE trial.
A new genomic test can predict a patient's risk of developing severe COVID-19, according to research from the University of Virginia Health System. The test, called CovGENE, analyzes genes expressed in a person's blood to determine if they may experience a severe disease course with increased risk of death.
Valentin Fuster, MD, PhD, is honored with the TCT Career Achievement Award for his transformative work in interventional cardiology and patient care. He has made significant global contributions to cardiovascular medicine.
Researchers at UNSW Sydney have made significant discoveries about embryonic blood stem cell creation that could one day eliminate the need for blood stem cell donors. Two studies have emerged from UNSW researchers in this area that shine new light on how precursors to blood stem cells occur in animals and humans, and how they may be i...
A study from Linköping University shows that individuals with type 1 diabetes should keep their mean long-term sugar level below 53 mmol/mol (7.0%) to avoid serious damage. The risk of eye- and kidney complications increases as the level increases.
A new blood test has shown promising results for detecting multiple types of cancer from tumor DNA in the blood, enabling early detection and potentially changing cancer screening practices. The test's accuracy and effectiveness have been demonstrated in a recent study, with high sensitivity and specificity rates.
Researchers found higher total and non-HDL cholesterol levels associated with GenX exposure in a new study. Legacy PFAS chemicals like PFOS and PFNA were most strongly linked to elevated cholesterol, particularly in older participants.
A large study found that obstructive sleep apnea is independently associated with an increased risk of cancer. Patients with more severe OSA were also at a greater risk of developing blood clots. Additionally, a second study linked OSA to a decline in mental processing powers, particularly in the elderly.
Researchers at Tel Aviv University develop a groundbreaking method to eradicate glioblastoma brain tumors by targeting astrocytes and starving them of energy. The study found that in the absence of these brain cells, tumor cells die and are eliminated, offering a promising basis for developing effective medications.
A meta-analysis of genetic studies found a stronger link between blood types A and O and early stroke, suggesting that people with these gene variants may be more likely to develop blood clots leading to stroke. Those with blood type A had an increased risk and those with blood type O had a decreased risk compared to other blood types.
Researchers at Brain Chemistry Labs have developed a new blood test for ALS using microRNA sequences, which accurately discriminated between patients and healthy individuals. The test works even with varying environmental conditions, offering hope for rapid diagnosis and improved patient outcomes.
A study published in Circulation found that moderate or vigorous physical activity can lower the risk of developing heart failure. The research, which analyzed data from over 94,000 adults, suggests that increasing physical activity duration and intensity may provide greater protection against heart failure.
A clinical trial has shown that full-dose anticoagulation therapy is more effective than standard-dose prophylactic anticoagulation in preventing blood clotting complications in COVID-19 patients. The study found a significant reduction in venous or arterial clotting complications among patients who received full-dose treatment.
Researchers developed a novel blood test that measures cell-free DNA to evaluate PAH severity and predict survivability. The test showed significant improvement over conventional tests and may allow doctors to intervene faster to prevent disease progression.
African American adults with higher levels of religiosity and spirituality may be more likely to meet key cardiovascular health metrics. The study found associations between religious behavior, spirituality, and improved health outcomes in terms of diet, physical activity, and smoking.
The study analyzed blood samples from bottlenose dolphins in the northern Gulf of Mexico, finding changes in gene expression related to immune response and oxidative stress. The results provide new insights into the health impacts of oil spills on marine life.
Researchers at RCSI found that patients with Long COVID syndrome have a blood-clotting imbalance due to high levels of von Willebrand Factor and low levels of ADAMTS13. The study suggests that this imbalance contributes to symptoms such as shortness of breath and fatigue.
Researchers developed a blood test that predicts poor outcomes in patients with traumatic brain injury (TBI), allowing clinicians to make decisions earlier on possible treatment. The test, which measures protein biomarkers GFAP and UCH-L1, showed high accuracy in predicting death and severe disability six months after injury.
Researchers found that adults with low blood urate levels are more likely to have low skeletal muscle mass and strength. This association is also linked to a higher risk of early death, particularly due to weight loss and adverse body composition.
A Rutgers scientist has developed a highly sensitive DNA test that can detect Lyme disease in horses, a condition that can cause long-term complications. The test, called genomic hybrid capture assay, was tested on a sick horse and successfully identified the pathogen, allowing for early diagnosis and treatment.
A 1g reduction in daily salt intake could prevent nearly 9 million cases of heart disease and stroke in China by 2030, saving 4 million lives. This is based on a modelling study that estimates the impact of reducing salt intake across the nation.
A West Virginia University study explores the link between pregnancy, sedentary behavior, and cardiovascular disease risk in women. The research aims to investigate whether physical activity can reduce or eliminate this accelerated risk development in women.
Researchers found that astrocytes can transfer their mitochondria to damaged neurons after a brain hemorrhage, stimulating the production of an enzyme that neutralizes free radicals. This treatment showed improved neurological recovery in mice, but not if the mitochondria were without the protective enzyme Mn-SOD.
A new analysis shows that combining two anti-platelet drugs can reduce the risk of graft failure after coronary artery bypass surgery, but also increase the risk of bleeding. The study found a significant reduction in graft failure rates with dual therapy, but more bleeding events requiring medical attention.
A pooled data analysis of 21 international clinical trials involving nearly 30,000 people found that salt substitutes lowered blood pressure and reduced the risk of heart attack, stroke, and early death. The benefits were consistent across different geography, age, sex, and health conditions.
Researchers at Weill Cornell Medicine found that disrupting circadian clocks leads to increased fat cell growth and insulin production. Stress and other factors can throw the body's 'clocks' out of rhythm, contributing to weight gain.
Researchers found that higher suPAR levels were associated with increased risk of blood clot formation in COVID-19 patients. Combining suPAR and D-dimer may improve predicting who is at high or low risk of blood clots, enabling targeted therapies to prevent critical outcomes.
Researchers discovered that vitamin K acts as an antioxidant, inhibiting ferroptotic cell death and identifying FSP1 as the warfarin-insensitive enzyme responsible. This finding has implications for treating Alzheimer's disease and acute organ injuries.
A new light-based sensor harnesses the light-guiding properties of spider silk to detect and measure small changes in the refractive index of a biological solution, including glucose and other types of sugar solutions. The sensor is practical, compact, biocompatible, cost-effective, and highly sensitive.
Research suggests that chemicals produced by gut microbes after eating red meat may contribute to cardiovascular disease. The study found a 22% higher risk of atherosclerotic cardiovascular disease associated with increased red meat consumption, which was partly attributed to elevated levels of TMAO and related metabolites in the blood.
A new study published in the Journal of the American Heart Association found that walking for exercise at a pace that induces leg pain or discomfort improves walking ability among people with peripheral artery disease. The study involved 264 participants who walked at home at either a comfortable pace or a pace that induced leg symptom...
A new study published in the Journal of the American Heart Association found that people with high genetic risk for stroke can reduce their risk by 30-45% by adopting a healthy cardiovascular lifestyle. The study followed 11,568 adults over 28 years and showed that modifying lifestyle risk factors can offset genetic risk.
Hospitalized COVID-19 patients with high blood viscosity have a 60% higher death rate than those with low blood viscosity. The study suggests that checking for blood viscosity early on could help determine the best treatment course and improve outcomes.
A UNC Charlotte-led team has invented a new biomolecular anticoagulant platform that holds promise as a revolutionary advancement over current blood thinners. The technology uses programmable RNA-DNA fibers to prevent blood clotting as needed, then be swiftly eliminated from the body.
Researchers found that CXCL9 levels were higher in pre-fracture blood samples of Chinese men with subsequent hip fractures, improving the prediction of osteoporotic hip fracture risk in men. In contrast, no association was found between CXCL10 and hip fracture risk in either gender.
A study found that individuals with a rare genetic variant common in people of East Asian descent are at higher risk of vessel reclog during or shortly after endovascular therapy for ischemic stroke. The researchers analyzed data from 277 East Asian adults who received the treatment between 2011 and 2021.
Researchers developed a heart-healthy diet based on traditional Chinese cuisine that reduced sodium levels by half, increased dietary fiber, and cut fat intake. The study found significant blood pressure reductions among participants, with potential implications for cardiovascular disease prevention.
A recent clinical trial found that low-dose benzbromarone was more effective in reducing blood urate levels in patients with renal urate underexcretion. The study showed that more participants in the benzbromarone group achieved the target blood urate level of < 6 mg/dL compared to those receiving febuxostat.