Researchers developed a computer model revealing how single brain cells in nematode worms sense and process environmental information to drive decision-making. The study found that sensory cells use salt cues as 'navigation beacons' to direct foraging behavior, controlling the animal's search strategy.
Researchers found that ribociclib achieved pharmacologically-relevant concentrations in tumor tissue, while everolimus showed minimal penetration. The combination is promising for brain cancer treatment and could lead to new therapeutic drug combinations.
A new study found that people hospitalized with COVID-19 have elevated levels of autoimmune antibodies in their blood, which are strongly linked to disease severity. Patients with high levels of these autoantibodies were five to seven times more likely to develop severe disease than those with stable antibody levels.
A study conducted by RCSI has demonstrated that a saliva PCR test is almost as accurate as the standard nose and throat swab, enabling greater capacity for frequent testing. The saliva screening represents a less invasive alternative with the potential to increase compliance with screening.
Researchers emphasize the importance of high-quality evidence for efficacy and safety when evaluating cannabis-based medicinal products in pediatric epilepsies. The authors caution that unlicensed products pose risks to children with epilepsy and warn against using them as a Trojan horse for the cannabis industry.
A new study analyzes millions of Twitter posts during three major hurricanes to develop a method for measuring social cohesion. The researchers found that monitoring social media chatter can help decision makers understand how communities communicate during disasters and identify areas for improvement.
A new study from Brigham and Women's Hospital found significant racial-ethnic differences in sleep health, with white adults having the best sleep outcomes and Black adults facing the worst. The research used data from over 1,700 adults and identified factors such as irregular timing and duration, insufficient sleep duration, and high ...
Researchers found that large herbivores can reduce wildfire damage by mitigating fire-prone vegetation. Effective solutions depend on factors such as herbivore population density and diet. Integrating extensive grazing into land management policies could help mitigate wildfires.
A new paradigm in breast cancer screening has been established with immediate-read screenings during the pandemic. This approach reduces racial and ethnic disparities in same-day diagnostic imaging, while speeding up diagnoses.
Researchers examined changes in life expectancy after allogeneic blood or marrow transplantation over four decades. The study found improved survival rates and reduced risk of death among transplant recipients.
Research suggests that increased complement factor C1q expression is responsible for chronic inflammation and secondary neuronal loss after mild traumatic brain injury. Blocking C1q expression counteracts these outcomes, suggesting a potential role for this molecule in modifying post-TBI disease.
New research explores conditions for humans and wolves to coexist peacefully in rural communities. Successful approaches to supporting communities have been identified, highlighting the importance of recognizing and celebrating traditional knowledge and skills in living alongside large carnivores.
A new study of 61,000 Microsoft employees found that working from home causes workers to become more siloed in how they communicate, engage in fewer real-time conversations, and spend fewer hours in meetings. The study's findings suggest that a full-time remote workforce may have a harder time acquiring and sharing new information.
The NIH is funding a $185 million research initiative to study genomic variation and its impact on human health and disease. The project aims to identify relevant genetic variants for clinicians, leading to improved treatment options.
Researchers have discovered that elevated levels of serotonin can prevent the development of compulsive cocaine seeking and addiction in mice. This is achieved through the activation of serotonin receptors and inhibition of synaptic transmission between key brain regions, thereby reducing the risk of addiction.
Researchers have synthesized the first 1D cuprate material that can be doped, providing systematic data to understand its behavior. The study suggests that the Hubbard model, a prominent theoretical framework, is missing a key ingredient: an unexpectedly strong attraction between neighboring electrons.
A randomized clinical trial found that students who received eye exams and glasses through a school-based vision program showed improved reading scores and academic achievement over one year. However, these positive effects were not sustained at two years after the program ended.
A new software, ModTect, identifies RNA modifications using pre-existing sequencing data, revealing associations with cancer survival outcomes. The study found dysregulation of the epitranscriptome in patients across multiple cancer types, associated with cancer progression and survival.
Researchers reconstructed the bottom water temperature record in the Northwest Barents Sea over the last 18,000 years and found that warmer temperatures led to increased methane seepage. The study suggests that these events played a key role in driving the retreat of the former ice sheet and destabilizing gas hydrates.
A study by Penn State found that people are more likely to believe fake news in video format, with 58% of participants believing a fake video was real, compared to 33% who read the article and 48% who heard an audio version. The researchers suggest that this is due to the perceived realism of videos, which can lead to a
A new study from the University of Pennsylvania and the University of Bristol found that exposure to false tweets about e-cigarettes' harm can deter adult smokers from quitting. The study recruited 2,400 UK and US adults who were not using e-cigarettes and showed them different health-related information on Twitter.
A study of 120 older Taiwanese adults found 45.8% experienced sleep problems, linked to living with a partner or needing to get up at night. The study suggests early recognition of these issues can lead to improved health outcomes for this population.
A study by researchers at Mainz University found that digital presence of service employees improves customer loyalty. The study, published in the Journal of Marketing Research, showed that customers perceive websites with images or videos of service employees as more attractive and memorable, leading to increased customer loyalty.
Researchers discovered that particulate emissions from auxiliary heaters can be significantly higher than those of idling gasoline vehicles, raising concerns about their environmental impact. The study highlights the need for further research on the use and development of heaters to reduce emissions.
Scientists have discovered a hydraulic jump mechanism that injects water vapor from the troposphere to the stratosphere above supercell thunderstorms. This process, which can occur several kilometers above the storm, drives intense hydration of the lower stratosphere and may play a major role in severe weather events.
A one-year study found that increased concentrations of fine particulate matter (PM2.5) and lower ventilation rates were associated with slower response times and reduced accuracy on cognitive tests, affecting employees' productivity.
The American Academy of Sleep Medicine has released a new clinical practice guideline recommending referral to upper airway or bariatric surgery for adults with obstructive sleep apnea who are intolerant of CPAP therapy. The guideline provides strong recommendations for treatment, considering factors such as BMI and patient adherence.
Researchers have successfully bonded gallium nitride and diamond without intermediate layers using surface-activated bonding. The resulting GaN-on-diamond material demonstrates stability even at extreme temperatures of up to 1,000℃, enabling the development of highly conductive semiconductors for high-power devices.
In the Brazilian Amazon, small towns are practicing a self-sustaining circular economy by converting waste into inputs for production. The Carauari community produces 100 metric tons of processed fish per year, generating resources from waste that fuel other activities.
Researchers at UMD are developing CRISPR-Combo systems to improve genome editing and crop regeneration. The technology aims to reduce the time and cost of breeding new crop varieties with enhanced nutritional and agronomic traits.
A study found that the ability to lose control over HIV is linked to a decrease in proliferative and cytolytic ability of immune cells, years before actual virus loss. In contrast to other infections, T cell dysfunction here impairs their response only to HIV.
Scientists have identified two new candidate genes, ULK4 and PTTG1, that positively influence the development of an embryo by restoring a strong Sonic Hedgehog signaling pathway. This finding provides new insights into the causes of holoprosencephaly, a congenital malformation affecting around one to four in every 1,000 unborns.
The new center will focus on identifying age-related changes that impact the development, progression, and experience of Alzheimer's disease and related dementias. Researchers will also investigate how factors such as race, age, female sex, and genetic predisposition contribute to racial and geographic disparities in dementia.
A multicenter clinical trial tested the use of lurbinectedin in patients with small cell lung cancer (SCLC), which did not meet its primary end point of overall survival. However, the combination of lurbinectedin and doxorubicin was found to be active in patients with SCLC after one prior platinum-based chemotherapy.
A study by Indiana University researchers found that individuals' socioeconomic status and social networks play a significant role in shaping their decisions about health controversies. Higher-status people faced fewer consequences for resisting medical guidelines, while those with lower statuses experienced more scrutiny. The study em...
A study compared four common DNA extraction methods and found that each method produced slightly different results due to varying 'how' factors. Researchers can now make informed decisions about their methods to optimize results.
Researchers discovered that protein phosphatase 2 (PP2A) is a key player in the development of preeclampsia, a condition characterized by high blood pressure and excess protein in the urine. Inhibiting PP2A with a drug may be a viable treatment option for preeclampsia.
A Penn State-led international research team developed laser-induced graphene (LIG) for wearable health devices, offering superior conductivity and heat resistance. The LIG foam exhibited electrical properties, while fibrous structures showed better performance, opening possibilities for sensing devices.
A recent study of 100 high-risk breast cancer patients revealed that the timing of breast reconstruction does not significantly affect long-term body image scores. Women who received immediate, delayed, or no reconstruction recover from negative impacts within four years of surgery.
Researchers have found that maternal diabetes can cause premature aging of neural tissue, leading to birth defects such as neural tube defects. A study published in Science Advances suggests that treatments could be developed to prevent miscarriages and certain birth defects in babies born from mothers with diabetes.
A new study by Xi'an Jiaotong-Liverpool University found that cultural context greatly affects the likelihood of unhappy employees becoming entrepreneurs. Countries with low uncertainty avoidance and high social acceptance of entrepreneurship have a stronger link between job satisfaction and entrepreneurial intent. In contrast, countri...
Air pollution attributed to lung cancer ranks highest in Balkan countries and Poland, particularly among those aged 50-69. The top five countries are Serbia, Montenegro, North Macedonia, Bosnia/Herzegovina, and Poland.
Researchers found that young female black bears in Asheville, NC, weigh nearly twice as much as those in national forests and reproduce at a younger age, producing cubs by their second birthday. The study's findings raise questions about the diet and foraging activities of urban bears.
A new study found hospitals employing more inpatient nurse practitioners have lower surgical mortality, higher patient satisfaction, and lower costs of care. Nurse practitioners enhance hospital success by improving clinical excellence, patient satisfaction, and reducing per-patient expenditures.
A study by University of Cologne researchers found that negative student expectations outweighed positive ones regarding remote learning during the pandemic. Students feared a decrease in social interaction, quality of teaching, and feedback, while hoping for increased flexibility and improved media competency.
A new study in the Journal of Marketing uses big data from over 100 million social media user engagements to derive marketing insights. The research captures latent relationships among thousands of brands and across many categories, revealing a highly precise market structure. This allows product managers to identify potential threats ...
Researchers have identified a molecule called fractalkine that can boost the production of brain cells producing myelin, a key factor in diseases such as multiple sclerosis. The study's findings suggest that fractalkine could be used to treat certain neurodegenerative disorders by restoring lost myelin.
Researchers have shown that physical exercise normalizes metabolic abnormalities caused by cancer, reducing anemia and associated fatigue. Exercise regenerates metabolism, blunting excessive blood cell formation and destruction, leading to improved tolerance of chemotherapy and radiotherapy.
The American Association for the Advancement of Science (AAAS) has launched a revamped website, integrating its six journals and elevating scientist voices through improved navigation and visuals. The new platform offers readers a more immersive experience, with features such as interactive study images and customizable reading modes.
The Center for Integration of Modern Optoelectronic Materials on Demand will develop new semiconductor materials and scalable manufacturing processes for applications in displays, sensors, and quantum communication. The center aims to connect academic research with industrial and governmental needs, educating a diverse STEM workforce.
Researchers built a robot that mimics the movement of mantis shrimp, which can deliver impressive forces. The study sheds light on the biology of mantis shrimp and reveals how they control their movements using geometry.
Researchers will examine protective immunity in older adults and assess the duration of immunity against emerging strains of COVID-19. The study aims to inform booster vaccine recommendations for seniors.
A team of scientists at ETH Zurich has discovered a new correlated state in twisted double layers of graphene, where negatively charged electrons and positively charged holes pair up to form an electrically neutral state. This state can transmit information or conduct heat without conducting electric current.
The European Medicines Agency (EMA) and the US Food and Drug Administration (FDA) have applied a similar mindset when advising live biotherapeutic product developer YSOPIA Bioscience. This collaboration has provided valuable regulatory feedback for the company's clinical development efforts. The review highlights the need for harmonize...
A study on dating and married couples in India found that relationship satisfaction and love were significantly lower post-lockdown compared to pre-lockdown. Non-traditional activities like cooking, watching movies, and sharing household chores were associated with higher levels of connectedness and intimacy.
A new study suggests that same-day discharge for high-risk patients undergoing hip and knee replacement surgery is safe and feasible. The research found no increase in complications or adverse outcomes with same-day discharge compared to inpatient surgery.
A study of 541 survivors in Kenya found children were 1.6 times more likely to be attacked during the day and 1.7 times more likely to be attacked in private, compared to adults. The research highlights the need for policy-makers to address sexual and gender-based violence (SGBV) risks in national crisis policies.
Researchers developed a robust, deep neural network model to analyze automobile traffic impacts of construction zones. The model estimates hourly traffic volumes without adjustment factors, helping transportation agencies plan for efficient work zone operations.
Researchers at Johns Hopkins Medicine used food science concepts to study membrane-free droplets in cells, finding they are highly organized and respond to the environment. They discovered a protein called MEG-3 that stabilizes these droplets, allowing them to separate and react quickly to changes.
Researchers developed WebFRIS, a web-based platform to provide socio-economic vulnerability analysis and simplify flood risk information. The tool can help formulate targeted solutions and enhance social capacity and resilience in flood-prone regions.