Articles tagged with Blood
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at McMaster University have developed a surface that repels all components of human blood except for the critical cytokine Interleukin-6 (IL-6), which can be measured with high accuracy and sensitivity.
Washington State University scientists developed a method to detect Alzheimer's disease biomarkers in blood, 10 times more sensitive than current technology. The artificial enzyme, called a nanozyme, can detect the biomarkers at levels lower than commercial ELISA tests.
Researchers found that a D-dimer blood test alone can accurately identify patients at risk of deep vein thrombosis (DVT), allowing for targeted follow-up with ultrasound examinations. The study suggests this simplified approach could reduce unnecessary tests and improve diagnosis accuracy.
A study by University of Zurich's Brain Research Institute found that early childhood trauma can lead to changes in lipid metabolism and glucose levels in offspring and grand-offspring. The researchers discovered a molecular mechanism involving the PPAR receptor, which is activated by fatty acids and regulates gene expression.
Two studies suggest individuals with blood type O may have a lower risk of COVID-19 infection and reduced likelihood of severe outcomes. In contrast, those with blood groups A and AB may be more likely to experience severe clinical outcomes and organ complications.
A new blood test, the Dublin-Boston score, accurately predicts which COVID-19 patients will develop a severe form of the disease. The score uses the ratio of pro-inflammatory IL-6 to anti-inflammatory IL-10 levels and can inform doctors on best treatment options.
Researchers found a group of neurons in female mosquitoes' stylets that activate only when sugar, salt, and other components of blood are present together. This discovery opens the door to further examination of novel forms of taste detection and unique feeding strategies.
Higher HMGB1 levels associated with obesity, inflammation and cardiovascular disease in younger adults, particularly females and blacks. The study found a link between circulating HMGB1 levels and increased blood pressure, stiffer arteries and inflammation.
Researchers found that IgG antibodies remain stable for up to 105 days after symptom onset in COVID-19 patients, while IgA and IgM antibodies decay rapidly. Saliva can be used as an alternative biofluid for antibody testing due to detectable levels of spike protein-specific antibodies.
Exposing diabetic mice to electromagnetic fields normalizes two major hallmarks of type 2 diabetes, including reduced blood sugar levels and improved insulin sensitivity. The effects are long-lasting, suggesting a potential EMF therapy for managing diabetes during sleep.
A UNICEF study reports that 800 million children have high lead values in their blood, posing permanent brain damage risks. The study highlights the need for international measures to address lead exposure, particularly among marginalized groups.
Researchers discovered that iodide levels increase in people's and animals' blood during severe stress, such as trauma or hibernation. This finding could lead to new treatments for traumatic injuries and COVID-19 by harnessing the body's natural response to stress.
Research reveals that older adults are less able to regulate body temperature and hydration during exercise in hot environments due to decreased sensitivity to elevated blood osmolality. This can lead to increased risk of heat-related injuries and adverse heart problems, highlighting the importance of staying hydrated.
Scientists at CNIC designed an algorithm that estimates cardiovascular risk in healthy middle-aged individuals based on variables like age, blood pressure, diet, and biomarkers. The EN-PESA algorithm provides a personalized risk profile for those with subclinical atherosclerosis or high short-term disease progression risk.
A team from the University of Pittsburgh is using a $1.1M grant to optimize small-diameter tissue-engineered vascular graft design and manufacturability. They aim to develop a feasible alternative to decades-old vessel harvesting methods, with the goal of reducing complications like stenosis.
A team of researchers at Case Western Reserve University has identified new biomarkers in the blood that can indicate damage to brain tissue, which could help emergency clinicians quickly recognize minor strokes. The discovery has the potential to reduce delays in treatment and improve patient outcomes.
A new study on chimpanzees shows that a plant-based diet and substantial opportunities for exercise can reduce cardiovascular disease risk to human levels. Free-ranging chimpanzees in sanctuaries exhibit lower body weight and lipid levels, indicative of better health.
A large observational study suggests that individuals with type 2 diabetes are 36% more likely to develop vascular dementia and 9% more likely to be diagnosed with non-vascular dementia compared to their diabetes-free counterparts. The risk of Alzheimer's disease is not higher in those with type 2 diabetes.
A study published in Diabetologia suggests that regular heat exposure through hot baths is associated with improved glycated haemoglobin levels and reduced body weight in patients with type 2 diabetes. The research found daily hot-tub bathing to have beneficial effects on cardiovascular risk factors, including blood pressure.
Researchers at Lund University have discovered biomarkers to predict how type 2 diabetes patients will respond to metformin treatment. The study, conducted on 363 participants, shows promise for personalized therapy and reducing side effects.
Researchers discover reduced glucagon sensitivity in people with fatty liver and type 2 diabetes, leading to increased glucose production. This finding opens up new possibilities for early detection and treatment of the diseases.
A new blood protein test can detect the severity of head trauma with high accuracy and speed, potentially saving millions in medical expenses annually. The research team developed a point-of-care testing device that uses a hand-held device to measure glial fibrillary acidic protein (GFAP) levels in patient blood.
A Rutgers study found that children on oral steroids are at higher risk of developing diabetes, high blood pressure, and blood clots, with high-dose steroid users facing the greatest risk. The study, which examined over 933,000 US children, also found that these complications were more common among those with autoimmune diseases.
A new machine learning model accurately identifies children most at risk of lead poisoning, equitably targeting resources to prevent poisonings. The model is about twice as accurate as previous simpler models and considers various factors such as housing, economic status, and sociodemographic data.
The Texas Heart Institute will develop the first fully implantable circulatory support device for pediatric patients, aiming to stop advanced heart failure progression. Led by Dr. O.H. Frazier, the team will conduct preclinical studies and collaborate with international consultants.
Research reveals that Type 2 diabetes affects brain function in older women, leading to sensory and motor deficits. A unique fNIRS technique detects decreased oxygenated blood use in the brain, suggesting underlying mechanisms such as muscle changes and cortical dysfunction.
Patients with severe COVID-19 infections who have high levels of the blood clotting protein factor V are at risk for serious injury from blood clots. Critically ill patients with low levels of factor V appear to be at increased risk for death due to a coagulopathy resembling disseminated intravascular coagulation.
Researchers found that fibroblast growth factor 1 repairs damaged perineuronal nets in the brain, a critical response required for sustained diabetes remission. The discovery sheds light on the intricate biology of the brain's response to the protein and may lead to more effective diabetes treatments.
A blood test detecting SARS-CoV-2 presence in patients with confirmed COVID-19 can predict severe cases, highlighting the importance of early treatment and monitoring. Admitted patients without detectable virus have a low risk of severe symptoms.
Research reveals that babies born with higher levels of cadmium may be at increased risk of developing childhood asthma and allergies. Cadmium exposure has been found to interfere with immune systems and increase allergic reactions.
A new wearable device could accurately assess blood loss due to hemorrhage using seismic vibrations and electrical signals from the heart. The device would provide a numerical score indicating the severity of cardiovascular system performance, helping first responders make life-saving decisions.
A new physiological test for diagnosing autism spectrum disorder (ASD) has shown promise, accurately identifying 124 of 131 children with ASD regardless of co-occurring medical conditions. The test measures metabolites in a blood sample and predicts diagnosis with minimal impact from other health issues.
Research suggests that not all vegetarian diets are created equal, with healthier choices linked to maintaining normal blood pressure, blood lipids, and blood sugar. Whole grains, fruits, vegetables, nuts, and olive oil were found to be key contributors to better heart health.
Researchers found that therapeutic and prophylactic doses of blood thinners reduced mortality by roughly 50 percent in COVID-19 patients. The study also showed that anticoagulation therapy was associated with improved outcomes both in and out of the intensive care unit.
A new study aims to determine if sleep optimization interventions can help adults with Type 1 diabetes improve their sleep and glycemic control. Participants will receive a wearable sleep tracker and brief phone counseling sessions.
A meta-analysis published in eLife reveals low HDL cholesterol is the most common lipid disorder in Latin America and the Caribbean. The study suggests that efforts to boost HDL cholesterol may provide the greatest heart health benefits to people living in these regions.
Researchers at Lund University found that a strict six-week low-calorie diet had the greatest positive effect on health markers after bariatric surgery. The operation itself caused minor changes, and most effects disappeared after six weeks.
Researchers developed an algorithm to monitor high blood sugar in COVID-19 patients, reducing secondary infections and kidney issues. The tool identifies risk categories based on hyperglycemia severity, insulin resistance and inflammatory markers.
Researchers identified five blood biomarkers associated with increased odds of clinical deterioration and death in COVID-19 patients. Elevated levels of these biomarkers were linked to inflammation and bleeding disorders, increasing the risk of ICU admission, ventilatory support, and mortality.
A new study found that prenatal Viagra treatment worsened growth-restriction in baby sheep by impairing the fetus' ability to redirect blood flow to essential organs. This impairment occurred despite lower levels of oxygen in the fetal blood, suggesting a potential mechanism underlying increased morbidity observed clinically.
Research examines neuroendocrine effects of grief, finding elevated cortisol levels in bereaved individuals with possible long-term health consequences. The study calls for more research on potential markers of neuroendocrine activity associated with grief to inform tailored interventions.
Researchers developed a blood test that can identify babies at risk of serious neurodisabilities like cerebral palsy and epilepsy just hours after birth. The test looks for specific genes being switched on or off, which may provide new targets for treating brain damage before it becomes permanent.
Researchers at EPFL have developed a synthetic inhibitor of coagulation factor XII that efficiently blocks blood clotting without causing bleeding side-effects. The inhibitor has high potency and selectivity, but its short retention time requires constant infusion to achieve sustained thrompobrotection.
A new analysis of data from the ALLSTAR study published in the European Heart Journal shows that cell infusions, also known as cardiosphere-derived cells (CDCs), can benefit patients with heart disease by reducing the volume of blood the heart holds and a blood protein that measures heart failure severity. The findings contradict previ...
A new study suggests that COVID-19 may cause deadly blood clots in pregnant women and those taking estrogen, highlighting the need for anticoagulation therapy or discontinuation of estrogen medicines. Research is underway to understand how the coronavirus causes blood clots, which could inform prevention strategies.
Researchers used computational models to study the effects of thinner biological tissues on transcatheter aortic valve replacement. The findings indicate that thinner tissues can lead to high levels of 'flutter energy', causing blood damage and accelerating leaflet deterioration.
A new blood test has demonstrated remarkable promise in discriminating between individuals with and without Alzheimer's disease. The test measures phospho-tau217, a protein found in tau tangles, and shows great accuracy in detecting the disease, even in its early stages.
Researchers have identified a blood test target, phosphorylated tau 217, that correlates with the presence of amyloid plaques in the brain. This protein can be detected in the blood of people who have yet to show signs of forgetfulness or confusion, making it a promising tool for early Alzheimer's diagnosis.
A new study found elevated levels of transforming growth factor beta-induced protein (TGFBIp) in hospitalized COVID-19 patients, correlating with disease severity. The research suggests TGFBIp could serve as a viable therapeutic target to treat severe inflammation and cytokine storms in patients with severe COVID-19.
A recent study by the University of Bath found that healthy adults can consume twice their normal calorie intake without experiencing immediate metabolic problems. The research revealed that blood sugar and lipid levels remained within normal ranges despite consuming large amounts of calories.
Researchers detected novel fluoroethers in 85% of participants' blood, representing 24% of total PFAS, and showed faster excretion rates compared to legacy PFAS. The study aimed to understand the effects of these chemicals on human health.
A new study published by The Endocrine Society found that cinnamon supplementation lowered abnormal fasting glucose levels and improved response to eating carbohydrates. Cinnamon was well-tolerated without adverse effects.
A Vanderbilt University Medical Center study found that post-surgical bleeding is associated with a higher mortality rate compared to blood clots. The researchers analyzed nearly 15 years of data on millions of patients and found that bleeding had a consistent signal for mortality, while blood clots did not.
Scientists at Joslin Diabetes Center discovered that increased blood sugar levels can impair aerobic fitness and muscle adaptation in mice and humans. Despite this, regular aerobic exercise is still recommended for maintaining health, especially when combined with dietary changes.
Scientists identify ten regions of the genome linked to long lifespan, healthspan, and longevity, finding a potential link between iron metabolism and healthy aging. The study's findings suggest that maintaining healthy levels of iron in the blood could be key to slowing aging and living longer.
Researchers found severely limited exercise capacity in adults with type 2 diabetes, increasing risk of heart failure. Subtle impairments in blood flow and heart function were detected using advanced imaging techniques.
Researchers developed a new use for a common blood test to adjust T3 dosage, suggesting improved cardiac function and reversal of heart failure genes. The study suggests that brain natriuretic peptide (BNP) levels can be used to titrate T3 required, providing a potentially life-saving treatment for heart failure.
Researchers found COVID-19 patients with symptoms of inadequate blood supply to the lower extremities had larger clots and higher rates of amputation and death. In contrast, those with only leg symptoms were more likely to avoid amputation or death.
A review of available evidence suggests that prediabetes is associated with a higher risk of all-cause mortality and cardiovascular disease in both the general population and patients with a history of heart disease. Screening and proper management of prediabetes may contribute to primary and secondary prevention of CVD.
A new finger-stick test can estimate radiation exposure in mice with high accuracy, using microRNA biomarkers. The test distinguishes between various doses of radiation, including those requiring triage, and could improve acute radiation syndrome diagnosis and treatment.