Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
A new drug lead has been developed to treat type 2 diabetes, improving blood sugar levels without nausea and weight loss. The research combines two molecules using a novel technique called 'corrination', reducing vomiting compared to existing GLP-1R agonists.
The study provides a comprehensive understanding of the diversity of blood thinners in leech saliva, shedding light on their potential use in hospital settings. The leech genome sequence offers critical insight into the evolution of bloodfeeding in leeches and may revolutionize the treatment of certain medical conditions.
Scientists at the University of Sussex have identified a potential pattern within blood that signals the presence of motor neuron disease. The discovery could significantly improve diagnosis with a future development of a blood test that identifies the unique biomarker, simplifying and speeding up diagnosis.
Researchers have developed a blood test that can accurately diagnose frontotemporal lobar degeneration (FTLD) and predict disease severity. The test measures neurofilament light chain levels in the blood, which are associated with FTLD progression, clinical phenotype, and prognosis.
A new study found that older adults with low vitamin K levels had a higher risk of death over 13 years compared to those with adequate vitamin K levels. The research suggests that vitamin K may have protective health benefits as we age, particularly in reducing the risk of death.
A new study of regular cannabis users found that high-potency marijuana concentrates spike blood levels of THC more than twice as much as conventional weed, but do not lead to greater impairment. Despite this, the study raises concerns about the potential long-term health risks of concentrated cannabis use.
A recent study published in the Journal of the American Society of Nephrology found that kidney function deteriorates with age, even in healthy individuals. The research, involving over 3,000 participants from Norway, Germany, and Iceland, suggests that kidney decline is a natural part of aging.
A study found that more than half of COVID-19 ICU patients developed clinically significant blood clots undetected by routine screenings. Researchers recommend using thromboelastography (TEG) tests to identify these patients and administer additional blood thinners.
A study published in Radiology found that 51% of patients with a pulmonary embolism were diagnosed in the Emergency Department, and 72% of PE diagnoses occurred in patients not requiring ICU-level care. Early detection using CT angiography was key to treatment, and preventive blood thinners should be considered for COVID-19 patients.
A new study reveals that metabolic differences in Humboldt penguins' blood can indicate their nesting habitat, with distinct patterns of sugars found in sheltered and exposed nests. The findings suggest that penguins in exposed areas are more likely to be exposed to air pollution.
Researchers are developing a novel approach to protein analysis using iron-detecting nanosensors. The technology detects defective iron-carrying proteins in blood, which could help explain anemia and lead to new therapeutics. This project has the potential to provide a baseline for protein analysis in the future.
High-resolution imaging of human placenta reveals uniform oxygenation levels and efficient blood flow, while also discovering rapid draining from veins and utero-placental pump contractions that facilitate better circulation and fetal growth. These findings improve placental models and optimize MRI protocols for better diagnosis.
A blood test using neurofilament light chain may predict recovery time after concussion, especially for those with multiple concussions. High levels of the biomarker are associated with severe symptoms like post-traumatic stress disorder and depression years later.
Researchers discovered that copper ions are primarily bound to ceruloplasmin and serum albumin in the blood, with implications for diagnosing and treating Alzheimer's disease. The study's findings provide new insights into normal copper metabolism and its disturbances in genetic diseases.
A new study published in Experimental Physiology found that fire service instructors experience higher levels of inflammation, which may lead to chronic health problems. The researchers suggest limiting their exposure to nine times per month to reduce the risk of cardiovascular disease.
A recent study presents an automatic method to detect and segment the intrauterine cavity using artificial intelligence and deep learning techniques on MRI data from 71 pregnancies. The proposed method achieves high segmentation performance, highlighting its potential for use in daily clinical practice as a surgical planning method.
A new blood test can identify women at risk of developing type 2 diabetes up to 10 years after delivery, allowing for potential interventions such as diet and exercise. The test uses metabolic markers that are present in the blood of women who have had gestational diabetes.
Researchers have discovered a link between exposure to certain environmental chemicals and an increased risk of chronic kidney disease. The study analyzed data from 46,748 US adults and found that elevated levels of seven chemicals were associated with markers of kidney disease.
A new analysis found that fewer people with COVID-19 suffer from stroke compared to previous reports. However, strokes in patients with the virus tend to be more severe and have poorer outcomes.
A blood test detecting neurofilament light chain can predict which people with multiple sclerosis will experience worsening symptoms and disability over the next year. The study found that individuals with high levels of this biomarker were more likely to develop significant disability and secondary progressive MS.
Researchers are studying COVID-19's effects on the brain, including stroke, anosmia, and seizures. They hope to find better treatments for patients at risk of developing cognitive problems.
A new study found that treatment with antibodies and steroids restored heart function in most children with COVID-19-related multi-system inflammatory syndrome. The majority of patients recovered quickly with intravenous immune globulin and adjunctive steroid therapy, suggesting a promising approach to managing this condition.
Researchers found critically ill COVID-19 patients with severe blood clotting who were at high risk of developing complications like renal failure, venous blood clots, and stroke. The study linked blood clotting measurements with patient outcomes, suggesting early testing may help identify and treat dangerous complications.
A clinical trial found that anti-clotting drugs alone are as effective as graduated compression stockings in preventing blood clots. The study suggests that current guidelines should be revised for patients undergoing elective surgery who are at moderate or high risk of VTE.
Research at NYU Langone Health found a link between elevated blood levels of toxic chemicals and an increased risk for celiac disease in young people. Young females were eight times more likely to become gluten intolerant, while males were twice as likely with fire-retardant exposure.
A new analysis of outpatient COVID-19 clinic data provides clues to distinguish between patients with COVID-19 and those with other conditions mimicking its symptoms. Key findings include fever not being a reliable indicator, COVID-19 often presenting with various permutations of cough without fever, and loss of the sense of smell as a...
A study published in Brain found that a lag in blood drainage from the deep region of the brain is associated with ventriculomegaly and can be detected with MRI. The researchers identified this biomarker as a potential predictor for dementia and ventriculomegaly, which can be reversed by removing excess fluid.
A new study found that a 'soft opt-out' system for organ donation increased consent rates by 2.1 times compared to England, with the impact taking several years to be fully realized. The Welsh system allowed organs to be donated without explicit consent from patients or their families.
A new genetic risk score identified more men at increased risk for abdominal aortic aneurysm and could benefit from screening to detect it prior to rupture. The study suggests that current screening recommendations should be extended to include testing for those with high polygenic risk scores.
A study published by King's College London found that spaceflight and combined oral contraceptive pill use do not increase the risk of venous thromboembolism in female astronauts. The research looked at 38 flights between 2000 and 2014 and proposed more frequent blood tests during astronaut selection and training.
The American Thoracic Society warns of the dangers of equating COVID-19 symptoms with high altitude pulmonary edema, highlighting key differences in pathophysiology and treatment. Clinicians must rely on scientific evidence to guide treatment, as oxygen therapy is ineffective for COVID-19-related lung injury.
A study by RCSI University of Medicine and Health Sciences found that Irish patients with severe COVID-19 infection experience abnormal blood clotting, leading to micro-clots in the lungs. This abnormal blood-clotting disorder contributes to a worse prognosis and increased risk of ICU admission.
A multicancer blood test safely detected 26 undiagnosed cancers and enabled potentially curative treatment in a study of over 9,900 women. The test was found to be complementary and additive to standard screening methods for detecting breast, colon, and lung tumors.
A blood test developed by Thrive Earlier Detection Corp. has identified multiple cancers in over 10,000 women without a prior history of cancer. The study found that the test more than doubled the number of 'screen-detected' cancers, increasing from 25% to 52%.
Researchers have developed a multipurpose nanoscale bio-probe that allows precise monitoring of iron disorders in cells, tissue, and body fluids. The test is more sensitive and specific than current blood testing methods, enabling early disease diagnosis and potential prevention of serious diseases.
Researchers at University of British Columbia discovered that soil silicates can help control bleeding after injury by triggering clotting. The presence of soil in wounds activates a blood protein called coagulation Factor XII, leading to the formation of a plug and limiting blood loss.
A recent study has revealed that cardiac myosin, a prevalent protein in the heart, can cause blood to thicken or clot during a heart attack, worsening damage to heart tissue. Researchers are now working on creating a therapeutic compound to target this protein's procoagulant activity.
A new study suggests that local doctors in rural areas can safely and effectively care for patients with left ventricular assist devices, reducing travel burdens and improving survival rates. Shared medical care eliminates the need for extensive travel, eases financial and emotional strains on patients.
A team of researchers suggests using a drug commonly used for blood clots, tissue plasminogen activator (tPA), to help Covid-19 patients with severe respiratory distress. The approach is based on emerging data from China and Italy showing a disorder of blood clotting contributing to respiratory failure.
Researchers studied vampire bat behavior, finding that social grooming and food sharing can build trust among unrelated bats to form long-lasting bonds. This cooperation is crucial for survival, as vampire bats must rely on each other for blood meals or risk starvation.
Researchers have successfully produced human protein Apolipoprotein A5 (APOA5) in the laboratory to metabolize and clear excess levels of triglycerides. The study demonstrates a potential pathway for developing drugs that trigger this process.
Children's National Hospital researchers isolated bacterial extracellular vesicles from healthy donors, revealing the gut microbiome communicates with the brain. The discovery could lead to a novel way of addressing antibiotic resistance by targeting bacteria-derived RNA.
According to a new study, accidents involving drivers with low blood alcohol concentrations are more likely to cause harm to others than drivers with levels at or above the limit. The study found that stringent alcohol policies can reduce the likelihood of fatal accidents involving drivers with all levels of alcohol blood concentration.
Research reveals that children diagnosed with type 1 diabetes under 7 years old have a different form of the condition compared to those diagnosed at 13 or above. The study proposes two distinct endotypes: T1DE1 and T1DE2, which could lead to new treatments and a potential cure for some people.
New research suggests that higher concentrations of insulin-like growth factor-1 (IGF-1) may be a probable cause of breast cancer. Studies found an association between IGF-1 and breast cancer development, with higher levels linked to increased risk. The findings support a causal role of the IGF pathway in breast cancer development.
A large cohort study published in Annals of Internal Medicine found that apixaban was associated with a lower risk of stroke or systemic blood clots compared to rivaroxaban in patients with nonvalvular atrial fibrillation. The study also showed that apixaban was linked to a lower risk of gastrointestinal bleeding or bleeding in the brain.
A nationwide prospective cohort study found that adults taking Vitamin K antagonist medication (VKA) had a lower incidence of overall bleeding events compared to direct oral anticoagulants. However, the VKA group also experienced a significantly higher mortality rate over one year.
The Rutgers team's robotic device combines AI, near-infrared, and ultrasound imaging to accurately pinpoint blood vessels, outperforming human healthcare professionals in complex tasks. The device reduces injuries and improves procedure efficiency, enabling healthcare professionals to focus on other critical aspects of medical care.
A smartphone app detecting jaundice in newborns may prevent deaths and disabilities due to its accuracy and low cost. The app uses images captured on a smartphone camera to quantify the yellowness of the eye, similar to expensive hand-held devices.
Researchers studied 51 cats injured in California wildfires and found a high incidence of heart problems, including thickening of the heart muscle and blood clot formation. The study suggests that wildfires may be a harbinger of human health effects, with severe burns increasing cardiovascular changes.
A study published in Blood Advances found that hematologists with caregiving responsibilities had fewer first- or senior-author publications and less percent effort in research compared to those without. Men were negatively affected by caregiving duties, while women showed similar performance regardless of their caregiving status.
Scientists at Newcastle University have discovered a link between amyloid-beta levels in the blood and cardiovascular disease. Higher levels of amyloid-beta may indicate a higher risk of developing serious heart complications, such as heart failure and progression to heart disease.
A new simple blood test developed by the University of Bristol could help doctors diagnose brain tumors earlier, using fluorescent carbon dots and nanophotonics. The test aims to detect biomarkers such as Glial fibrillary acidic protein (GFAP) in blood samples.
A new study by West Virginia University found that 8.10% of newborns in the state had PETH levels consistent with late-pregnancy alcohol use, associated with developmental problems and cognitive deficits. The prevalence varied across the state, with higher rates in the Mid-Ohio Valley.
Adult lymphoma patients treated with CAR-T therapy reported improved physical and social function, as well as better emotional and mental health. The study suggests that CAR-T may not only extend survival but also improve quality of life after treatment.
A new type of heart valve, inspired by human venous valves, has been designed to adapt to a child's growth without losing functionality. The biomimetic two-leaflet design has shown promising results in benchtop studies and large animal models, potentially reducing the risk of blood clots and improving long-term device durability.
Researchers at EPFL discovered that fruit flies remove and excrete damage-causing lipids, preventing lipid peroxidation and ROS-induced inflammatory oxidized lipids. This mechanism may play an important role in other insects and even animals, helping to protect against oxidative stress damage.
Researchers create molecular 'fishing' technology using customized receptors to detect specific proteins in blood, offering a precise diagnostic tool for diseases and drug discovery applications.
A study by DZNE researchers found that a good blood supply to the hippocampus is crucial for healthy memory performance. Participants with doubly supplied hippocampi showed improved cognitive scores compared to those with single-supplied hippocampi or microbleeding, suggesting better oxygen delivery may be key.
A new study found that two popular bariatric surgeries can change patients' sensitivity to alcohol, increasing blood alcohol concentrations by 50% after consumption. Some women experienced reduced sensitivity, reporting almost no sedative effects from alcohol.