Articles tagged with Blood
A recent study has revealed that cardiac myosin, a prevalent protein in the heart, can cause blood to thicken or clot during a heart attack, worsening damage to heart tissue. Researchers are now working on creating a therapeutic compound to target this protein's procoagulant activity.
A new study suggests that local doctors in rural areas can safely and effectively care for patients with left ventricular assist devices, reducing travel burdens and improving survival rates. Shared medical care eliminates the need for extensive travel, eases financial and emotional strains on patients.
A team of researchers suggests using a drug commonly used for blood clots, tissue plasminogen activator (tPA), to help Covid-19 patients with severe respiratory distress. The approach is based on emerging data from China and Italy showing a disorder of blood clotting contributing to respiratory failure.
Researchers have successfully produced human protein Apolipoprotein A5 (APOA5) in the laboratory to metabolize and clear excess levels of triglycerides. The study demonstrates a potential pathway for developing drugs that trigger this process.
Researchers studied vampire bat behavior, finding that social grooming and food sharing can build trust among unrelated bats to form long-lasting bonds. This cooperation is crucial for survival, as vampire bats must rely on each other for blood meals or risk starvation.
Children's National Hospital researchers isolated bacterial extracellular vesicles from healthy donors, revealing the gut microbiome communicates with the brain. The discovery could lead to a novel way of addressing antibiotic resistance by targeting bacteria-derived RNA.
According to a new study, accidents involving drivers with low blood alcohol concentrations are more likely to cause harm to others than drivers with levels at or above the limit. The study found that stringent alcohol policies can reduce the likelihood of fatal accidents involving drivers with all levels of alcohol blood concentration.
Research reveals that children diagnosed with type 1 diabetes under 7 years old have a different form of the condition compared to those diagnosed at 13 or above. The study proposes two distinct endotypes: T1DE1 and T1DE2, which could lead to new treatments and a potential cure for some people.
New research suggests that higher concentrations of insulin-like growth factor-1 (IGF-1) may be a probable cause of breast cancer. Studies found an association between IGF-1 and breast cancer development, with higher levels linked to increased risk. The findings support a causal role of the IGF pathway in breast cancer development.
A nationwide prospective cohort study found that adults taking Vitamin K antagonist medication (VKA) had a lower incidence of overall bleeding events compared to direct oral anticoagulants. However, the VKA group also experienced a significantly higher mortality rate over one year.
A large cohort study published in Annals of Internal Medicine found that apixaban was associated with a lower risk of stroke or systemic blood clots compared to rivaroxaban in patients with nonvalvular atrial fibrillation. The study also showed that apixaban was linked to a lower risk of gastrointestinal bleeding or bleeding in the brain.
The Rutgers team's robotic device combines AI, near-infrared, and ultrasound imaging to accurately pinpoint blood vessels, outperforming human healthcare professionals in complex tasks. The device reduces injuries and improves procedure efficiency, enabling healthcare professionals to focus on other critical aspects of medical care.
A smartphone app detecting jaundice in newborns may prevent deaths and disabilities due to its accuracy and low cost. The app uses images captured on a smartphone camera to quantify the yellowness of the eye, similar to expensive hand-held devices.
Researchers studied 51 cats injured in California wildfires and found a high incidence of heart problems, including thickening of the heart muscle and blood clot formation. The study suggests that wildfires may be a harbinger of human health effects, with severe burns increasing cardiovascular changes.
A study published in Blood Advances found that hematologists with caregiving responsibilities had fewer first- or senior-author publications and less percent effort in research compared to those without. Men were negatively affected by caregiving duties, while women showed similar performance regardless of their caregiving status.
A new simple blood test developed by the University of Bristol could help doctors diagnose brain tumors earlier, using fluorescent carbon dots and nanophotonics. The test aims to detect biomarkers such as Glial fibrillary acidic protein (GFAP) in blood samples.
Scientists at Newcastle University have discovered a link between amyloid-beta levels in the blood and cardiovascular disease. Higher levels of amyloid-beta may indicate a higher risk of developing serious heart complications, such as heart failure and progression to heart disease.
A new study by West Virginia University found that 8.10% of newborns in the state had PETH levels consistent with late-pregnancy alcohol use, associated with developmental problems and cognitive deficits. The prevalence varied across the state, with higher rates in the Mid-Ohio Valley.
A new type of heart valve, inspired by human venous valves, has been designed to adapt to a child's growth without losing functionality. The biomimetic two-leaflet design has shown promising results in benchtop studies and large animal models, potentially reducing the risk of blood clots and improving long-term device durability.
Adult lymphoma patients treated with CAR-T therapy reported improved physical and social function, as well as better emotional and mental health. The study suggests that CAR-T may not only extend survival but also improve quality of life after treatment.
Researchers at EPFL discovered that fruit flies remove and excrete damage-causing lipids, preventing lipid peroxidation and ROS-induced inflammatory oxidized lipids. This mechanism may play an important role in other insects and even animals, helping to protect against oxidative stress damage.
Researchers create molecular 'fishing' technology using customized receptors to detect specific proteins in blood, offering a precise diagnostic tool for diseases and drug discovery applications.
A study by DZNE researchers found that a good blood supply to the hippocampus is crucial for healthy memory performance. Participants with doubly supplied hippocampi showed improved cognitive scores compared to those with single-supplied hippocampi or microbleeding, suggesting better oxygen delivery may be key.
A new study found that two popular bariatric surgeries can change patients' sensitivity to alcohol, increasing blood alcohol concentrations by 50% after consumption. Some women experienced reduced sensitivity, reporting almost no sedative effects from alcohol.
A study found that women living in green spaces had a later age at menopause, with an average age of 51.7 years compared to 50.3 years in areas with little green space. Lower cortisol levels and reduced risk of depression may contribute to this association.
Scientists have made a breakthrough in understanding the rapid reproduction of the malaria parasite by identifying crucial molecules involved in cell division. This discovery could pave the way for developing novel therapeutic strategies against the disease.
A study published in Nature Communications reveals a major link between protein FHR4 and age-related macular degeneration, affecting 1.5 million people in the UK alone. The findings show that higher levels of FHR4 in the blood increase the risk of AMD by activating part of the immune system.
A new protein called factor H-related protein 4 (FHR-4) has been linked to age-related macular degeneration. Higher levels of FHR-4 in the blood may indicate increased risk of developing the disease, which affects over 1.5 million people in the UK.
A new robot created by Rutgers University has performed as well or better than humans in blood sampling, providing quick results and reducing complications. The device includes an ultrasound-guided robot that draws blood from veins, and could be used in various medical procedures to improve patient outcomes.
Researchers at Oxford University have found a protein called Plexin D1 that detects disturbances in blood flow and triggers inflammation and plaque formation, leading to serious health problems. The discovery offers new hope for developing treatments to block plaques before they form.
A study published in the British Journal of Dermatology found that higher mercury levels in the blood are associated with an increased prevalence of non-melanoma skin cancer. Participants with high total or methyl mercury levels had nearly double or 1.7 times greater odds of non-melanoma skin cancer, respectively.
A UCLA-led study found that six blood proteins can be used to gauge a person's risk for cerebral small vessel disease, which affects an estimated 11 million older adults in the U.S. The test correlates with white matter changes in the brain and provides a more quantitative scale for evaluating the disease.
Researchers developed a novel gas imaging system to visualize and measure gases released through the skin in real-time. The system uses VOCs present in circulating blood to diagnose metabolic disorders, genetic diseases, and cancer.
A new study by the University of Alberta found that pregnant women with elevated fasting blood sugar levels are at a higher risk of complications, including large babies, high blood pressure, and preterm births. Despite receiving diabetes drug treatments, these women were more likely to experience adverse outcomes.
A study published in Radiology found that patients with abdominal aortic aneurysms and blood clots on the aorta wall experience faster growth and increased rupture risk. The researchers suggest adjusting imaging follow-up schedules for these patients to reduce the risk of rupture.
A groundbreaking study published in PNAS used a multi-modal precision health platform to identify adults at risk of key health conditions, including cancer, heart disease, and neurological disorders. The study found that integrating whole-genome sequencing with advanced imaging and blood metabolites led to clinically significant findin...
Overweight adults who followed the Mediterranean, Intermittent Fasting and Paleo diets experienced modest weight loss (2-4kg) and clinically significant improvements in blood pressure. The Mediterranean diet also improved blood sugar levels, while the fasting diet led to slightly more weight loss.
Researchers developed a total-body PET/CT scanner with advanced reconstruction techniques to capture radiotracer transport in humans at 100 ms timescales. This approach offers clear images of cardiac blood pool changes throughout the cardiac cycle, enabling real-time motion tracking and neural activity analysis.
A study published in PLOS Neglected Tropical Diseases found that typhoid prevalence is likely higher than estimated due to missed blood cultures, with patients more likely to have cultures if older, feverish or suspected urinary tract infection.
Researchers have analyzed the polychromy of the Pachacamac idol using non-invasive techniques, revealing that red is not blood but mercury from cinnabar. The study also confirms the idol's age as around 731 AD, with local ritual importance before Inca rule.
A pilot study of 25 donor-recipient pairs reveals young stem cell donors have previously undetected and potentially disease-causing mutations in their blood stem cells. These mutations, linked to post-transplant complications, are more prevalent in young donors than thought.
Researchers at UT Southwestern Medical Center found a significant association between malignant left ventricular hypertrophy and an increased risk of heart failure among black individuals. The study, published in the journal Circulation, suggests that early intervention can be beneficial in preventing future risk.
Researchers have identified a mechanism that contributes to clot formation in mechanical heart valves. By modifying the valve's design, turbulent vortices can be eliminated, reducing the risk of blood clots and strokes. This breakthrough could lead to life without blood thinners for thousands of people with artificial heart valves.
The American grasshopper's circulatory system responds dramatically to changes in body position due to gravity, affecting blood and air distribution. Physiological compensation mechanisms similar to vertebrates suggest an ancient, widespread response to gravitational forces.
Grasshoppers adjust their cardiovascular and respiratory activity in response to gravity, with mechanisms similar to those found in vertebrates. The study reveals that insects have functional valves and can control fluid flow to prevent blood pooling in the brain.
A new study published in Blood Advances reveals that patients with metabolic syndrome are more likely to experience recurrent blood clots. The study analyzed 151,054 patients diagnosed with deep vein thrombosis and found that those with comorbid metabolic syndrome conditions had a higher risk of VTE recurrence.
A study published in PLOS ONE found that using altruistic terminology may not be effective in targeting non-donors. Instead, focusing on a sense of social obligation could lead to better cut-through rates. The researchers also discovered that blood donors tend to have higher primary prosocial characteristics like altruism and empathy.
Researchers have developed a superhydrophobic material that repels blood and promotes fast clotting, making it ideal for use as a bandage. The material's antibacterial effect also reduces the risk of infection when changing bandages.
A new blood test has been developed to measure microRNAs in children's blood, which can indicate sufficient or inadequate sleep. This test may provide a more reliable metric for assessing sleep hygiene and predicting susceptibility to various health conditions.
A preliminary study found that losing a night of sleep increases tau levels in blood by an average 17-percent compared to a good night of sleep. Higher levels of tau may reflect clearance of proteins from the brain or elevated levels in the brain.
A study by Uppsala University found that sleeping deprivation for just one night increased tau protein levels in the blood of young, healthy men. This accumulation can start decades before Alzheimer's symptoms appear.
Researchers at Children's National Hospital developed a direct measurement technique for cardiac output in newborns, utilizing changes in blood velocity after injecting saline. The study used ultrasound dilution and reported promising results, with potential implications for personalized care of critically ill newborns.
A new study reveals that peripherally inserted central catheters (PICCs) increase the risk of blood clots and bloodstream infections in children. Children with a prior history of VTE, larger caliber catheters, or leukemia are more susceptible to these complications.
Researchers found that a ketone monoester drink can help participants with Type 2 diabetes and pre-diabetes better control their blood sugar levels without insulin changes. The study's lead author notes that while ketone supplements are not a magic bullet, they may be another strategy for managing the disease.
A team of researchers discovered a case of stagnant blood flow resulting in a clot in the internal jugular vein of an astronaut on the International Space Station. The study found that anticoagulation therapy was effective in reducing the size of the clot, but not eliminating it entirely.
A US astronaut on the International Space Station developed a deep vein thrombosis, prompting UNC expert Stephan Moll to consult and develop a treatment plan. Moll advised on using Enoxaparin and Apixaban to effectively treat the blood clot, which was successfully managed over 90 days.
A review article published in The New England Journal of Medicine suggests that intermittent fasting can improve blood sugar regulation, increase resistance to stress, and suppress inflammation. Studies have shown that this adaptation may trigger a slower metabolic process, which can lead to weight loss and reduced belly fat.
A study by McMaster University researchers found that levels of NT-proBNP, a common cardiac blood test, can predict cardiac and vascular complications after non-cardiac surgery. The test may help doctors identify patients at risk and inform treatment decisions.
A genetic risk score can identify individuals at a 3-fold increased risk of developing ischaemic stroke, a devastating condition. This scoring system may require more intensive preventive measures than current guidelines recommend.
A new study found that over 24 routine blood tests are affected by childhood obesity, including liver function tests and inflammation markers. This discovery could help doctors better interpret test results and provide more accurate diagnoses.