Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
Researchers discussed recent clinical study results comparing fibrinogen concentrate and cryoprecipitate in cardiac surgery, highlighting fibryga as a potential alternative for managing perioperative bleeding. The studies provide important data on fibryga's efficacy and safety in treating acquired fibrinogen deficiency.
A study of 1,400 UK children found that exposure to adverse experiences and stress at a young age is associated with elevated levels of inflammation in the blood. The researchers also found that this association persists into young adulthood.
Researchers observed vampire bats developing strong social bonds during captivity that persisted in the wild, suggesting shared history plays a role in maintaining relationships. The study used pioneering technology to track bat interactions and found test bats had stronger bonds with each other than control bats.
A large study of over 200,000 men found that high levels of 'free' testosterone and insulin-like growth factor-I (IGF-I) are associated with an increased risk of prostate cancer. The research suggests that these hormones could be modified to reduce prostate cancer risk, taking us a step closer to strategies for prevention.
Researchers at Boston University have made the first-ever images of cerebrospinal fluid washing in and out of the brain during sleep. The study shows that CSF pulses in rhythmic waves, closely tied to brain wave activity and blood flow, which could provide insights into age-related impairments and neurological disorders.
Researchers found that birds in constant traffic noise had lower levels of corticosterone in their blood compared to quiet environments. This suppression may protect against negative effects of chronic stress on the immune system. Chicks from noisy parents were also smaller but caught up after leaving the nest.
A study published in the American Journal of Human Genetics has identified 57 genetic variations associated with declines in blood oxygen levels during sleep. These findings provide insight into the hereditary basis of this trait and its relationship to sleep disorders and lung diseases.
Researchers at McMaster University have identified chemical signatures detectable in blood and urine that can accurately measure dietary intake. The study validates a panel of metabolites in urine and plasma that correlate with consumption of fruits, vegetables, protein, and fiber.
Researchers at Institut Pasteur have identified GDF11 as a blood factor involved in weight loss and aging. The study shows that GDF11 mimics the benefits of calorie restriction, inducing metabolic changes and promoting neurogenesis in the brain.
A pilot program introducing safer mining practices in Nigerian gold mining communities has reduced blood lead levels among miners by 32%. The study, published in the British Medical Journal Occupational and Environmental Medicine, also found that women miners experienced lower reductions in lead levels. The project's success demonstrat...
Patients who received courteous care during blood draws reported a 390% reduction in pain perception, with 82% experiencing excellent pain control. Empathetic providers were found to make a substantial difference in patient experience.
Researchers are examining whether molecules in young blood could help treat age-related disorders, such as macular degeneration and Alzheimer
A new blood test increased diagnoses of women with heart attacks by 42%, but the gender gap in treatment remains. Women were 50% less likely to receive recommended treatments after a heart attack diagnosis.
Research from The University of Queensland found that even small amounts of alcohol during pregnancy can cause insulin-resistance in male rats. Male rats exposed to low levels of prenatal alcohol showed signs of becoming diabetic at six months old.
A clinical trial found that testosterone significantly increases young women's running capacity, with a notable impact on anaerobic performance and lean body mass. The study suggests that allowing female athletes with high testosterone levels to compete without hormone reduction could be fair.
A systematic review and meta-analysis found that nonpharmacologic treatments, such as massage and touch therapy, were more effective than pharmacologic treatments in reducing aggression and agitation in adults with dementia. The authors recommend prioritizing nonpharmacologic approaches over medications due to potential harms associate...
A Tulane University study links long-term soil lead changes to children's blood lead levels, highlighting urban areas' role in exposing kids to toxic metals. The research also reveals socioeconomic disparities in lead exposure, with black children more likely to have higher blood lead levels.
Researchers discovered a 44% decrease in topsoil lead between 1999 and 2017 and a 64% decline in children's blood lead levels between 2000 and 2016. These findings suggest a link between reduced soil lead and lower blood lead levels in children.
Researchers at the University of Dundee develop a blood test to detect desmosine, an amino acid released by diseased aortas into the blood and urine. This test improves diagnosis and monitoring of aortic aneurysms, potentially saving lives by identifying patients at risk.
The American Heart Association's new scientific statement identifies the benefits and risks of novel interventional devices for treating pulmonary embolism. The devices, which remove or dissolve clots in the lungs, are shown to be effective but carry moderate risks, particularly in patients with intermediate-risk PE.
An observational study of 1,442 mother-child pairs found associations between maternal lead blood levels and intergenerational risk of childhood overweight/obesity. Adequate folate levels in mothers were also shown to mitigate this risk, suggesting a potential protective effect.
Experts discuss the importance of vaccination in preventing serious complications from diseases like measles, influenza, and cystic fibrosis. The panel emphasizes that vaccines are effective in keeping disease rates low when majority of people are vaccinated.
A new blood test can detect liver cancer and life-threatening vascular complications in diabetic patients with high accuracy. The test analyzes DNA in just a few drops of blood and has already shown promise in detecting other major cancers.
A new model simulates fluid dynamics in arteriovenous grafts, finding that vein flexibility can reduce disrupted blood flow. The study suggests several options for improving AVG designs to prevent thrombosis and extend their lifespan.
The Blood and Immune Deficiency-Cellular Therapy Program (BID-CTP) integrates expertise from multiple medical specialties to treat rare blood and immune system diseases. Patients with hundreds of different primary immune deficiency diseases can now receive unified care through a single, multi-specialty team.
A Stanford-led study reveals that turmeric is sometimes adulterated with lead-laced chemical compounds in Bangladesh, leading to elevated blood lead levels among consumers. The researchers aim to shift consumer behaviors, reduce incentives for the practice and develop business opportunities to promote lead-free turmeric.
A study published by researchers from the Turku Bioscience Centre found changes in circulating molecules in the blood that may be new markers of type 1 diabetes. This discovery could provide an early window for intervention and prevention of the disease.
Research found patients with highly variable blood sugar control are more likely to experience adverse cardiovascular events and microvascular complications. The study suggests that even a moderate increase in HbA1c variability is associated with increased risks of mortality, cardiovascular disease, and diabetes-related complications.
A new study finds that drawing blood cultures after starting antimicrobial treatment can result in a significant loss of available clinical information. The study suggests that drawing blood cultures prior to treatment may be more effective in identifying the bacteria causing the infection and selecting the right antibiotic.
A new study has found that initiating antibiotics immediately before obtaining blood cultures significantly affects their sensitivity and ability to diagnose bacterial and fungal infections. This change in guidelines may reduce mortality rates from sepsis, a life-threatening condition with a 20% mortality rate.
A recent study published in Annals of Internal Medicine found that early blood sampling for microorganisms is critical to treating sepsis. Emergency rooms must follow sepsis guidelines, which demand trained personnel and proper equipment, to prevent organ damage and death.
A new study from Ohio State University found that eating iron-rich foods with tomato sauce can decrease lycopene uptake by twofold. This could have significant implications for individuals consuming high amounts of lycopene and iron, such as those eating Bolognese sauces or fortified cereals.
Researchers found that carbohydrate content and meal type are the most important factors affecting carb-counting accuracy. Larger meals tend to have more errors, while smaller meals have fewer mistakes.
Researchers found that 2.5% of women and 12.1% of men without established CVD could derive net benefit from aspirin treatment for 5 years. The study used data from a well-characterized web-based decision support program in New Zealand, identifying persons likely to benefit from aspirin treatment based on personalized benefit-harm analy...
A study found that desensitization from peanut oral immunotherapy can be maintained by continuing a modest dose of peanut protein, offering more protection against allergic reactions. Participants who passed food challenges had lower initial levels of antibodies and indicators of allergic activity in their blood.
A recent study found that rabbit and mouse papillomaviruses can be transferred by blood to their respective hosts, raising the possibility of human papillomavirus (HPV) transmission through blood in humans. The researchers also detected HPV sequences in mucous membranes like the tongue and genitals, as well as in the stomach.
Researchers from Trinity College Dublin isolated a family of proteins linked to better control of blood sugar levels in type 2 diabetes patients. These IL-36 cytokines alter the intestinal microbiome, potentially mitigating insulin resistance and glucose build-up.
A blood test has been shown to detect lung cancer earlier, identifying 32% of cases with a high specificity of 90%. This could lead to reduced late-stage presentations and improved survival rates for patients.
A new study developed a blood-based biomarker panel that can diagnose posttraumatic stress disorder (PTSD) in male combat veterans with 77% accuracy. The panel uses genomic, metabolic, and protein biomarkers to identify genetic and cellular changes associated with PTSD.
A team of researchers, including Northwestern University professor Gary Galbreath, analyzed the physical condition of the antlers and confirmed they belonged to a Schomburgk's deer. The antlers showed signs of being fresh, despite being excised from the deer's head, suggesting the deer may still be alive today.
A study by Loyola Medicine researchers found that pharmacist presence in the ER speeds up delivery of coagulation drug, improving patient outcomes. Patients with a bedside pharmacist spent less time in ICU (2 days vs. 5 days) and hospital overall (5.5 days vs. 8 days).
A UK study found that vegetarians and pescetarians have a lower risk of coronary heart disease (CHD) than meat eaters, but a higher risk of stroke. This may be due to low blood levels of total cholesterol or certain vitamins. The study included 48,188 participants over 18 years.
A study using a blood marker of inflammation found an association between late adolescence inflammation and death among Swedish men up to age 57. The results suggest that chronic inflammation in young adulthood may increase the risk of mortality decades later.
Research in mice reveals that XX sex chromosomes increase blood fat levels, leading to narrowed arteries and higher heart attack risk. The study suggests a new therapeutic target for treating coronary artery disease in post-menopausal women.
The new guidelines clarify the diagnosis and treatment of acute pulmonary embolism, emphasizing the importance of quick and reliable diagnosis to prevent death. The guidance also provides recommendations on the use of anticoagulant drugs and clot busters, as well as distinguishing between fresh thrombi and chronic obstructions.
A new blood test has been developed to detect concussions and subconcussive injuries in children and adults, which can cause wear and tear on the brain over time. The study included over 700 patients with varying injury mechanisms, revealing elevated levels of two biomarkers GFAP and UCH-L1 in patients with non-concussive head trauma.
Scientists discover two compounds that can dry up tick saliva, reducing feeding and potentially limiting pathogen transmission. The treatment effectively kills ticks within 12 hours, a significant timeframe for pathogen transmission.
A new blood test developed by UCSF has shown high accuracy in detecting concussions absent on CT scans, with the potential to prevent unnecessary radiation exposure and improve patient care. The test measures brain protein levels, which are significantly elevated in patients with traumatic brain injuries.
Researchers at Rutgers University have found that brown fat can filter and remove branched-chain amino acids (BCAAs) from the blood, which are linked to diabetes and obesity. The study suggests that environmental factors such as cold temperatures or spicy foods may be able to control BCAA uptake by brown fat.
A recent study by the University of Pennsylvania School of Medicine found that nicotine-free e-cigarettes can immediately reduce vascular function and impair blood flow. The researchers used MRI exams on healthy adults to measure changes in blood vessels after vaping a single e-cigarette, revealing significant damage.
Researchers have discovered bone-like particles in the peripheral circulation of individuals with advancing age, which may lead to vascular calcification and restricted blood flow. These particles are potentially more dangerous due to their sharp edges and could contribute to diseases such as heart attack and stroke.
A study by University of Helsinki found that 84% of Finnish trotters had soft tissue damage in the bit area, with mild, moderate, and severe lesions detected. The researchers hope their developed classification system will facilitate comparative research.
Researchers studied skulls of New World leaf-nosed bats to understand the evolution of specialized diets and faces. They found that heterochrony influenced development, leading to primate-like faces for fruit-eating bats and wolf-like faces for bird- and rodent-eating bats.
Researchers found a significant association between elevated post-exercise troponin levels and an increased risk of severe cardiovascular disease or death. The study suggests that exercise may serve as a stress test for the heart, allowing for early identification of susceptible individuals who require closer monitoring.
A study found that a diet with reduced carbohydrate content, high protein content, and moderately increased fat content improves patients' ability to regulate their blood sugar levels. This diet also reduces liver fat content and has a beneficial effect on fat metabolism in type 2 diabetics.
Researchers developed a new technique to analyze blood spatter patterns, which can help investigators determine the origins of blood spatters and potentially identify the weapon used. The study's findings reveal that bullet shape and velocity play a crucial role in determining blood spatter patterns.
Research from the University of Copenhagen found that remnant particle cholesterol in the blood is constantly increasing and often remains at a high level for life. Maintaining a normal body weight is key to reducing remnant cholesterol and triglycerides, according to experts.
Researchers have developed a blood test that can detect Alzheimer's disease with 94% accuracy when combined with age and genetic risk factor. The test measures levels of amyloid beta in the blood to predict brain changes, potentially allowing for earlier intervention.
The Endocrine Society recommends regularly screening older adults for heart disease and diabetes risk, prioritizing lifestyle modification as the first-line therapy. Patients with at least three metabolic risk factors should be screened annually, while those with one or two risk factors should be screened every three years.
A study found that plastic ingestion can have a significant negative impact on seabirds, causing reduced blood calcium levels, body mass, and kidney function. The research also revealed that the simple presence of plastic is enough to cause negative consequences, regardless of the amount.