A new blood test has been developed to detect early stage ovarian cancer using a bacterial toxin, with the test detecting significant levels of cancer glycan in over 90% of women with stage 1 ovarian cancer. The test also showed 100% accuracy for later stages of the disease and has potential for simple liquid biopsy monitoring.
A new study found that inflammatory skin disorders like psoriasis increase the risk of type-2 diabetes. Improving skin health could be crucial for controlling blood sugar levels and reducing diabetes risk.
A new study at Johns Hopkins Medicine shows that educating hospitalized patients quickly can lower missed dose rates of blood clot-preventing medications. The educational intervention led to a 47% decrease in non-administration rates due to patient refusal, with no change on control floors.
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Researchers found that hot-water immersion improved inflammatory markers and blood sugar levels in overweight men. A two-week treatment period showed a reduction of fasting blood sugar and insulin levels as well as improved low-grade inflammation.
Scientists from CNRS and partners have found a promising strategy for protecting neurons after a stroke, involving the extracellular matrix. The new approach, using an agent mimicking structural components of this matrix, has shown effectiveness in rats and may complement existing clot-elimination techniques.
A new study found that Agile Implementation reduced central-line associated blood stream infections by 30 percent, improving patient safety and reducing costs. The methodology enabled fast and effective implementation of evidence-based solutions, involving all stakeholders in the change management process.
A water T2 biomarker discovered by Texas Tech University Health Sciences Center El Paso researcher David P. Cistola can detect individuals at risk of developing Type 2 diabetes, allowing for potential disease prevention through lifestyle modifications or therapies.
A recent Ohio University study found that individuals who experience fear while donating blood tend to overestimate the frequency of fainting and other adverse reactions. The study, conducted by Christopher R. France and Janis L. France, revealed a significant correlation between fear levels and exaggerated risk assessments.
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The Infectious Diseases Society of America (IDSA) has released new guidelines for outpatient parenteral antimicrobial therapy (OPAT), emphasizing the importance of review by an infectious diseases specialist before starting treatment. Regular monitoring and blood tests are also recommended to ensure patient safety.
A recent study of peripheral pulse oximeters found that non-approved devices accurately measure oxygen saturation above 90%, potentially ruling out hypoxemia. However, below 90%, medical-grade pulse oximeter measurements are recommended for accurate patient management decisions.
The Center for Advancing Point-of-Care Technologies (CAPCaT) will assist inventors developing innovative point-of-care devices and technologies for patients with heart, lung, blood, and sleep disorders. The center aims to reduce in-patient hospital stays and improve quality of life.
A new flexible sensor maps blood-oxygen levels over large areas of skin and organs, allowing for real-time monitoring of healing wounds. This innovation could benefit patients with diabetes, respiration diseases, and sleep apnea by tracking blood-oxygen levels 24/7.
Researchers found patients with broken heart syndrome who developed cardiogenic shock had a higher short-term and long-term mortality rate compared to those without the complication. The study suggests careful long-term follow-up is crucial for this patient group.
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Researchers found that higher lead and mercury levels in the blood were associated with increased levels of bad cholesterol and total cholesterol. The study suggests a potential link between heavy metal exposure and cardiovascular disease.
Researchers found that very low troponin levels can rule out stress-inducible ischemia, allowing doctors to avoid routine stress testing. This could reduce healthcare costs and radiation exposure by triaging individuals with stable CAD before performing stress tests.
Researchers are exploring a new treatment using two existing drugs to reduce heart damage during cardiac surgery. The team will test the treatment in pigs and assess its safety and feasibility before moving to human trials.
The South African National Blood Service has increased the proportion of donations from black South Africans by fivefold since 2005. This significant improvement is attributed to the implementation of individual donation nucleic acid testing (NAT), which has reduced HIV transmission risks.
A team of researchers has discovered a biomarker, named cBIN1 Score, that measures muscle deterioration and protein regulation in the heart, indicating onset of heart failure. This simple blood test can aid doctors in diagnosing at-risk patients before symptoms appear.
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A University of Guelph study has found that opening up the blood vessels to an ovarian tumour can potentially improve the effectiveness of treatment. By creating a healthy blood supply, the tumour becomes more accessible to treatment, increasing success rates.
A recent study analyzed the impact of mass shootings on blood supply and demand for blood products. The research found that a call for immediate blood donation was unnecessary and resulted in wasted blood resources. The study suggests that cities develop protocols for mass casualty events, such as issuing calls for donations by ZIP code.
A new experimental vaccine has shown to reduce the risk of secondary strokes caused by blood clots for over two months without triggering an autoimmune response. The vaccine, S100A9, provides protection against blood clot formation and works as well as oral blood thinner clopidogrel in a major artery.
Stroke specialists often see conditions known as stroke mimics and 'chameleons' that can mimic ischemic strokes, making accurate diagnosis complicated. Accurate diagnosis requires a detailed history and neurologic examination to avoid administering clot-busting drugs incorrectly.
A clinical trial showed that low-phosphorus diets and medication can decrease FGF23 levels in hemodialysis patients. This reduction decreases the risk of cardiovascular problems and increases life expectancy.
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A new blood test developed by UNC Lineberger researchers demonstrates the ability to track HPV-linked head and neck cancer patients after treatment, reducing the need for costly imaging scans. Preliminary findings show that patients with positive blood tests had a higher risk of developing recurrence.
A recent study published in JAMA Surgery found that patients taking aspirin alone had similar protection against blood clots as those on anticoagulant treatments. Aspirin use has become increasingly popular among Michigan surgeons, with 70% of surgeons prescribing it to patients after knee replacement surgery.
A trial revealed that nurse-led care significantly improves gout treatment outcomes, including higher ULT adoption and better patient adherence. Patients receiving nurse-led care had lower urate levels, reduced flare-ups, and improved quality of life.
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A new blood test at emergency departments could quickly and accurately rule out heart attacks. A preliminary study of 350 patients found the test to be as effective as longer laboratory tests in ruling out heart attacks.
Researchers at UC Riverside successfully used CRISPR-Cas9 to disrupt serotonin receptor Aa5HT2B in mosquitoes, reducing body size, lifespan, egg development, and fat accumulation. This breakthrough offers a novel approach for controlling mosquito populations and diseases they carry.
A US study found that higher blood levels of omega 3 fatty acids from seafood are associated with a lower risk of unhealthy ageing, defined as survival free of major chronic diseases and without mental or physical dysfunction. Participants who consumed more seafood-derived EPA had a 24% lower risk of unhealthy ageing.
A new study suggests that a neck collar may help protect the brain of female high school soccer players from cumulative head impact exposure. The Q-Collar, designed to increase brain blood volume during collisions, showed no significant white matter changes in those who wore it.
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Researchers found that most hospital-acquired bloodstream infections come from patients' own gut, with 15 of 30 patients having the same strain in both stool and blood samples. The study used bioinformatics software to rapidly identify the source of infections, which could help address risk factors and prevent recurrence.
Researchers at Rush University Medical Center developed a metal-coordinated molecule, poly-zinc-liothyronine (PZL), which works well in laboratory studies and may provide an improved therapy for all hypothyroid patients. PZL's slow release of active hormone can supplement standard therapy, offering a more effective solution for treatme...
Researchers developed Prescience, a system that uses patient charts and sensor data to predict hypoxemia. The system provides explanations for its predictions, enabling anesthesiologists to better understand patient risks and prevent complications.
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A new study published in The BMJ suggests that genetics play a significantly larger role in the development of high serum urate levels than diet. Despite long-held assumptions about diet's impact on gout, researchers found that only a small percentage of variation in urate levels could be explained by food choices.
A study published in Neurology found that people with atrial fibrillation, an irregular heartbeat, are at a faster rate of decline in thinking and memory skills and a higher risk of dementia. Taking anticoagulants to prevent clots may decrease the risk of dementia.
Researchers used statistical tools to analyze data from 55 studies on dietary oils and found seed oils, such as sunflower oil and flaxseed oil, perform best in improving cholesterol. However, there are caveats, including the study only measured blood lipids and may not be applicable to clinical outcomes.
Researchers developed a glow-in-the-dark paper strip that can detect the presence of infectious diseases using antibodies in blood, offering a quick and affordable alternative to traditional lab tests. The test measures antibody concentration by analyzing blue-green light produced through bioluminescence.
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Researchers found that SHBG levels at baseline can predict insulin resistance years later in both men and women. Lower SHBG levels are associated with higher insulin resistance, a precursor to type 2 diabetes.
A new accelerated diagnostic protocol, HEART Pathway, is effective in identifying low-risk ED patients with acute chest pain who can be safely sent home without hospitalization or comprehensive cardiac testing. The study found a 6% reduction in hospitalizations and significant decreases in median length of stay and use of stress testing.
A study by University of Pennsylvania researchers identified a rare example where being older improves tissue function, leading to reduced scar formation. The key factor is a compound called stromal cell-derived-factor-1 (SDF1), which is secreted in the bloodstream and is more abundant in younger individuals.
Researchers at UNC will investigate the epidemiology of Zika virus in pregnancy and its effects on infant neurodevelopment. The team will follow infants exposed to Zika in Nicaragua and test new diagnostic protocols to understand the virus's impact.
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Colorado State University chemists are developing biologically friendly coatings to mitigate blood-device interactions in extracorporeal life support systems. These advancements aim to eliminate the need for blood thinners, reducing side effects and improving patient outcomes.
Researchers found that immediate compression therapy significantly reduced the risk of residual vein occlusion and post thrombotic syndrome in patients with DVT. The study suggests that starting compression therapy within 24 hours of diagnosis can prevent debilitating complications.
A blood test for microRNAs may help predict the likelihood of disease in dairy cows and improve animal welfare. This approach is already being applied to human disease diagnosis.
Researchers aim to develop and evaluate non-contrast based imaging methods to diagnose peripheral arterial disease without relying on gadolinium-based contrast agents. The proposed techniques have high applicability to other medical procedures, including venography and vessel wall imaging.
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A novel, paper-based method detects metabolite levels in blood using a bioluminescent sensor protein, measuring compounds like phenylalanine in minutes. The approach shows promise for point-of-care monitoring of diseases and injuries, potentially leading to faster diagnosis and management.
Researchers at Penn State are developing a new generation of blood pumps that use computational methods to predict clot formation and design safer devices. This could enable earlier intervention for patients with congestive heart failure, reducing recovery time and improving outcomes.
Researchers are developing portable sensors that can detect toxic metals like manganese in a single drop of blood. The sensors will enable faster and cheaper research as well as rapid detection of neurotoxins affecting cognitive development and neuromotor function.
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Researchers at Northwestern University developed a simple blood test called TimeSignature that can identify the body's precise internal time clock. The test measures gene expression markers and can be taken any time of day, allowing for more accurate diagnosis and treatment of diseases such as heart disease, diabetes, and Alzheimer's.
A new study published in the American Journal of Respiratory and Critical Care Medicine found that New York State's sepsis reporting mandate led to improved care and reduced mortality rates for critically ill patients. Patients who received standardized treatment protocols had shorter hospital stays and lower mortality rates.
A new lab-on-a-chip device developed by KU Leuven researchers can detect infections and viruses in blood with high accuracy, making it ideal for diagnosing people in developing countries. The device is simple, cheap to produce, and can be activated with a finger touch, allowing anyone to use it.
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Sherpas' unique physiological adaptations to high altitude may help improve oxygen delivery in critically ill patients. By increasing blood flow and delivering oxygen to tissues, Sherpas thrive at low oxygen environments, offering a potential alternative to traditional high oxygen content strategies.
The National Heart Lung and Blood Institute will award $20 million to four academic centers over five years, with UC San Diego receiving $5 million. The program aims to correct the lack of attention given to glycans in biomedical research and train 18 early-career glycoscientists.
A study found that a specific E. coli strain from retail poultry products is causing urinary tract infections in people, with nearly 80% of meat samples and 72% of patient cultures positive for the bacteria. The research suggests that cooking poultry thoroughly and handling it carefully are crucial to prevent foodborne illnesses.
Researchers reduced household lead levels and found significant reductions in dust lead levels, especially among black children. However, the intervention did not result in significant neurobehavioral improvements, such as improved IQ or behavior. The study suggests that eliminating residential lead exposure may be necessary to fully p...
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A new study found that using oral anticoagulants for 45 days after hospital discharge reduced the rate of non-fatal blood clots in medically ill patients. The trial, MARINER, showed no increase in major bleeding risk while offering protection against non-fatal blood clots.
A new study suggests that performing simple leg exercises while lying down can help prevent impairment of blood vessel function caused by a sedentary lifestyle. The research found that even a brief period of inactivity reduced the ability to rapidly increase blood flow to the lower legs.
A blood test can predict which patients with diffuse large B cell lymphoma are likely to respond positively to initial therapy. Researchers tracked circulating tumor DNA levels in 217 patients and found a correlation between rapid decline and improved outcome.
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A blood test using Kidney-injury-molecule-1 (KIM-1) can predict clear cell kidney cancer risk and survival up to five years before diagnosis, with higher levels associated with poorer outcomes. The test substantially improves accuracy in predicting kidney cancer risk.
A new blood test can quickly detect early signs of liver disease in dogs, enabling prompt treatment and reducing the need for invasive biopsies. The test is based on insights from human patients and has been successfully tested on 250 dogs.