Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
A team of researchers has identified biomarkers in the blood that can predict the accumulation of toxic fats in the liver, a sign of early fatty liver disease. The discovery has the potential to lead to a blood test to detect those at risk of advanced fatty liver disease and could represent a new approach in precision medicine.
A new study from Michigan Medicine reveals that pesticide exposure contributes to faster progression of amyotrophic lateral sclerosis (ALS). The research, published in the Journal of Neurology, Neurosurgery and Psychiatry, found that patients with higher levels of pesticides in their blood had a shorter median survival time.
A new machine-learning algorithm uses cholera antibody test results to identify recently infected individuals, making it easier to detect deadly epidemics. The algorithm was tested on a dataset of 1,569 blood samples and showed high accuracy in estimating the time window for cholera infection.
A new study found that eating 200g of blueberries daily for a month improves blood vessel function and reduces systolic blood pressure in healthy people. Anthocyanins, a type of phytochemical responsible for blueberry's color, play a key role in this effect.
A study found that one in four men aged 55-59 is at risk of needing further revision surgery, with serious complications surprisingly common in older people. The lifetime risk of revision surgery was highest during the first five years after surgery.
The CASSINI Trial found that while there was no significant reduction in venous thromboembolism or death over 180 days, cancer patients taking rivaroxaban had a lower incidence of these events while on the drug or during the treatment period.
Screening for irregular heartbeat has been proposed as a potential solution to reduce stroke risk, but experts disagree on its effectiveness. Mark Lown suggests that trained clinicians can accurately identify positive cases, while Patrick Moran raises concerns about the lack of evidence on screening's benefits.
Researchers have found evidence of pre-cancerous lung tumours in mice using a blood-based test, suggesting a potential early detection method for lung cancer. The study used mice with a mutation in the KRAS gene to model the disease and found that circulating DNA levels correlated with tumour size.
A new study found that removing at least 70% of the intracerebral clot is crucial for patients to make a meaningful recovery after a brain hemorrhage. The research, known as MISTIE III, involved 506 patients and showed that ideal outcomes were achieved when no more than 15 milliliters of clotted blood remained at the site of injury.
A study tested minimally-invasive surgery for brain bleeds and found it didn't improve functional recovery compared to medical therapy. However, the procedure was associated with fewer deaths and improved outcomes in patients with smaller blood clots.
A new reversal agent, andexanet alfa, effectively stopped acute life-threatening bleeding in patients taking factor Xa inhibitor blood thinners. Researchers found that good or excellent hemostasis occurred in 81.7% of patients after administering the reversal agent.
Researchers found that removing 70% or more of the blood via minimally invasive surgery can lead to better functional outcomes and milder disability one year later. The study also suggests that the amount of residual blood left at the end of treatment plays a crucial role in determining the success of the procedure.
A study at Vanderbilt University Medical Center found that African-American patients with blood type B can receive blood type A2 kidneys with similar outcomes. This new option has improved access to transplants for minority patients, increasing the number of available organs and reducing disparities in wait times.
A recent study published in the Journal of the American College of Surgeons found that minority patients with blood type B can receive kidneys from donors with blood type A2 without compromising their health. The study showed comparable patient and graft survival rates for both groups, but higher costs for type B recipients who receive...
Researchers found that a minimally invasive surgery combining clot-busting drug and catheter drainage reduced swelling and improved prognoses in hemorrhagic stroke patients. The study showed that every 10 milliliter increase in swelling volume was associated with a 25% higher risk of death at 30 days.
Researchers found a strong relationship between infections during delivery hospitalization and stroke within the following month. Women with an infection during delivery hospitalization were more than five times as likely to be readmitted to the hospital for stroke.
A recent study published in the journal Nutrients found that vegan meals increased beneficial gastrointestinal hormones in individuals with obesity, type 2 diabetes, and healthy participants. This increase in gut hormones can help regulate blood sugar, enhance insulin secretion, promote satiety, and support weight management.
A study of people who grew up in the era of leaded gasoline found that higher blood lead levels at age 11 were associated with signs of mental illness and difficult personality traits by age 38. Participants exposed to higher levels of lead as children were rated as more neurotic, less agreeable, and less conscientious than their peers.
A new blood test reliably detects signs of brain damage in people with Alzheimer's disease, even before symptoms of confusion and memory loss arise. The test may also identify neurodegeneration in other brain diseases, injuries, and conditions such as multiple sclerosis and traumatic brain injury.
Researchers at DZNE and HIH developed a blood test that detects neurofilament, a protein found in the blood, which accumulates long before clinical symptoms of Alzheimer's disease. The test accurately reflects the course of the disease and predicts future developments.
Research by University of Adelaide scientists has revealed that poor blood oxygenation during sleep is a significant indicator of the chance of heart-related death. Extended episodes of interrupted breathing while asleep also increase the risk.
Researchers have made significant progress towards developing a blood test for Alzheimer's disease, with sensitive assays able to detect smaller amounts of peptides that form when amyloid breaks down. A reliable blood test could aid in diagnosis and help identify participants for clinical trials, potentially leading to better treatments.
A new health check has been developed to discover the diets, migrations, and conservation needs of whale sharks. The research revealed that some whale sharks may have gone weeks or months without eating, and surprisingly, all tested showed signs of eating plants and algae.
Researchers found that trained alert dogs can detect hypoglycaemic episodes in 83% of cases, helping Type 1 patients regulate blood sugars non-invasively. The study provides the first large-scale evaluation of medical detection dogs in detecting hypoglycaemia.
Scientists have identified natural antibodies within protein corona that trigger immune system response to nanoparticles. Depleting these antibodies reduces complement system activation, enabling safe delivery of cancer-fighting drugs and imaging agents.
A large study published in The BMJ found that HRT tablets are associated with a higher risk of rare but serious blood clots, particularly those containing equine oestrogen. No increased risk was found for skin patches, gels and creams. The study provides important information for women and their doctors to make informed treatment choices.
Women taking HRT tablets are up to two times more likely to develop potentially life-threatening blood clots. The study found a higher risk for tablet treatments, particularly those containing horse urine-derived oestrogen, but no increased risk for patch, gel, or cream forms.
Researchers at the University of Arizona have discovered a protein in mosquitoes that prevents them from hatching. By blocking this protein, females can no longer produce viable eggs, leading to the death of embryos. This discovery could lead to the development of new drugs as birth control for mosquito populations.
A new study found that ketogenic supplements can delay tonic-clonic seizures caused by high levels of oxygen, even in a normal diet. The supplements increased blood ketone levels, providing therapeutic ketosis and resistance to seizures.
A new study found that eating one egg per day is associated with a blood metabolite profile linked to a lower risk of type 2 diabetes. Researchers identified several biochemical compounds in blood that predicted a higher risk of developing the disease, including tyrosine.
Chemists at McMaster University have identified new chemical signatures in a small amount of blood that could detect cystic fibrosis in infants earlier and more accurately. These biomarkers can be analyzed using mass spectrometry, reducing costs and anxiety for families.
Researchers found that ankylosaurs had a built-in air conditioner in their snouts, which was just as efficient as those in living animals. The long, twisty noses allowed for effective heat exchange and cooling of the brain.
A new study found a robust link between higher levels of several nutrient biomarkers in the blood and enhanced performance on specific cognitive tests. The analysis revealed that omega-3 fatty acids, carotenoids, lycopene, and vitamins B and D worked synergistically to improve brain health and cognition in older adults.
A Marshall University study found significant differences in umbilical cord blood metal levels between urban and rural newborns. Copper and molybdenum were higher in urban samples, while no marked differences occurred for other elements. The study suggests a potential link between prenatal exposure to toxins and neonatal outcomes.
A Scottish study found that changing the legal drink-driving limit did not reduce road traffic accidents despite substantial initial public awareness campaigns. The researchers suggest inadequate enforcement and publicity as possible reasons for the lack of impact.
Researchers at Aarhus University have made a breakthrough in understanding hereditary angioedema by identifying cellular defects leading to the rare disease. The study reveals that genetic mutations cause intracellular retention of C1-inhibitor, resulting in patients producing only 10-20% of normal levels.
Researchers found that people who eat a diet rich in red meat have triple the TMAO levels of those who eat a diet rich in either white meat or mostly plant-based proteins. However, discontinuation of red meat eventually lowers these TMAO levels, suggesting a promising new strategy for individualizing diets and preventing heart disease.
A new study found that 14% of people with Type 2 diabetes who don't require insulin test their blood sugar levels two or more times a day, exceeding medical guidelines. This can result in millions of unneeded tests and wasted insurance funds.
A study by Oregon State University found that consuming hazelnuts daily for 16 weeks improved magnesium levels and reduced low-density lipoproteins (LDL) in older adults. Urinary levels of a vitamin E breakdown product also increased, indicating an improvement in overall nutritional status.
A research team from Universitat Autonoma de Barcelona develops a new Double Factor Preimplantation Genetic Testing (DF-PGT) strategy using massive sequencing techniques. This allows for simultaneous diagnosis of genetic mutations and chromosomal alterations, increasing the security of the diagnosis and the viability of embryos.
A recent study found that opioids like methadone and buprenorphine can impair cognitive tasks and increase sleepiness, with four participants stopping their tests due to drowsiness. The study's results indicate that patients should be informed about the potential driving impairment caused by these medications.
A clinical trial found that a low dose of apixaban safely prevents blood clots in over half of newly diagnosed cancer patients. The strategy is expected to prevent clots in 57,000 people per year, saving lives and reducing healthcare costs.
The American Society of Hematology has released new clinical practice guidelines for venous thromboembolism, covering evidence-based recommendations for prevention, diagnosis, and treatment. The guidelines aim to improve care for patients with blood clots, addressing current uncertainties and variations in clinical practice.
Researchers found that starving ticks have higher activity levels and increased questing behavior to find a meal. Their metabolism speeds up by 100% after three months without food, preparing them for an imminent meal.
A new blood test has been developed to detect early stage ovarian cancer using a bacterial toxin, with the test detecting significant levels of cancer glycan in over 90% of women with stage 1 ovarian cancer. The test also showed 100% accuracy for later stages of the disease and has potential for simple liquid biopsy monitoring.
A new study found that inflammatory skin disorders like psoriasis increase the risk of type-2 diabetes. Improving skin health could be crucial for controlling blood sugar levels and reducing diabetes risk.
A new study at Johns Hopkins Medicine shows that educating hospitalized patients quickly can lower missed dose rates of blood clot-preventing medications. The educational intervention led to a 47% decrease in non-administration rates due to patient refusal, with no change on control floors.
Researchers found that hot-water immersion improved inflammatory markers and blood sugar levels in overweight men. A two-week treatment period showed a reduction of fasting blood sugar and insulin levels as well as improved low-grade inflammation.
Scientists from CNRS and partners have found a promising strategy for protecting neurons after a stroke, involving the extracellular matrix. The new approach, using an agent mimicking structural components of this matrix, has shown effectiveness in rats and may complement existing clot-elimination techniques.
A new study found that Agile Implementation reduced central-line associated blood stream infections by 30 percent, improving patient safety and reducing costs. The methodology enabled fast and effective implementation of evidence-based solutions, involving all stakeholders in the change management process.
A recent Ohio University study found that individuals who experience fear while donating blood tend to overestimate the frequency of fainting and other adverse reactions. The study, conducted by Christopher R. France and Janis L. France, revealed a significant correlation between fear levels and exaggerated risk assessments.
A water T2 biomarker discovered by Texas Tech University Health Sciences Center El Paso researcher David P. Cistola can detect individuals at risk of developing Type 2 diabetes, allowing for potential disease prevention through lifestyle modifications or therapies.
The Infectious Diseases Society of America (IDSA) has released new guidelines for outpatient parenteral antimicrobial therapy (OPAT), emphasizing the importance of review by an infectious diseases specialist before starting treatment. Regular monitoring and blood tests are also recommended to ensure patient safety.
A recent study of peripheral pulse oximeters found that non-approved devices accurately measure oxygen saturation above 90%, potentially ruling out hypoxemia. However, below 90%, medical-grade pulse oximeter measurements are recommended for accurate patient management decisions.
The Center for Advancing Point-of-Care Technologies (CAPCaT) will assist inventors developing innovative point-of-care devices and technologies for patients with heart, lung, blood, and sleep disorders. The center aims to reduce in-patient hospital stays and improve quality of life.
A new flexible sensor maps blood-oxygen levels over large areas of skin and organs, allowing for real-time monitoring of healing wounds. This innovation could benefit patients with diabetes, respiration diseases, and sleep apnea by tracking blood-oxygen levels 24/7.
Researchers found that very low troponin levels can rule out stress-inducible ischemia, allowing doctors to avoid routine stress testing. This could reduce healthcare costs and radiation exposure by triaging individuals with stable CAD before performing stress tests.
Researchers found patients with broken heart syndrome who developed cardiogenic shock had a higher short-term and long-term mortality rate compared to those without the complication. The study suggests careful long-term follow-up is crucial for this patient group.
Researchers found that higher lead and mercury levels in the blood were associated with increased levels of bad cholesterol and total cholesterol. The study suggests a potential link between heavy metal exposure and cardiovascular disease.
A team of researchers has discovered a biomarker, named cBIN1 Score, that measures muscle deterioration and protein regulation in the heart, indicating onset of heart failure. This simple blood test can aid doctors in diagnosing at-risk patients before symptoms appear.