Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
Researchers at UC Riverside are exploring a hormone-targeting approach to control mosquito reproduction, which is linked to blood feeding. The goal is to develop innovative vector control methods and potentially reduce the spread of diseases transmitted by mosquitoes.
Researchers at Lund University have found a direct link between the gastrointestinal flora and lung disease in the setting of blood transfusions. The composition of the gut bacteria drives the pathogenic immune response in the lungs during Transfusion Related Acute Lung Injury (TRALI), a complication that can be fatal.
A breakthrough discovery by RMIT University could enable early detection of Type 1 diabetes in newborns, potentially delaying or preventing the onset of the disease. The collaboration combines lab-on-a-chip technologies with biomarker detection to identify early loss of beta cells.
The University of Hong Kong research team developed a C-reactive protein sensor integrated onto a medical catheter, enabling real-time CRP sensing with a thickness less than one micrometer. This allows doctors to take immediate actions, speeding up testing and curing of inflammation by 30 times.
A study suggests that abnormal metabolism of three essential amino acids may contribute to the development of type 2 diabetes in women who have a history of gestational diabetes. Women with a history of gestational diabetes had higher levels of branched-chain amino acids in their blood, regardless of their dietary intake.
A recent study published in the European Respiratory Journal found that obstructive sleep apnea is associated with changes to brain structure similar to those seen in early-stage dementia. The study suggests that screening for OSA and treating it could help prevent dementia in older adults.
A new microfluidics technique has been developed to construct microchannels with efficient gas exchange, potentially delivering nearly a third of the oxygen needed by preterm newborns. The design uses both sides of the membrane for gas exchange and is more effective than previous single-sided counterparts.
A new blood test can determine an individual's internal clock, allowing for personalized drug administration and more effective treatment. The test identifies biomarkers that reliably report internal time, differentiating early and late types.
A Portsmouth researcher is developing a mathematical model to speed up the delivery of life-saving blood to victims of disasters, reducing blood wastage and loss of life. The model will inform venue and location for temporary blood donation centres, transportation routes, and quantities delivered.
A new observational study reveals that apixaban is potentially safer than warfarin in dialysis patients with atrial fibrillation, with a significantly lower risk of major bleeding. The study found that patients on apixaban had a 30% lower risk of major bleeding without a difference in stroke rate.
A new study published in Journal of the American Heart Association found that young adults who frequently binge drink are more likely to have risk factors for cardiovascular disease. The research revealed that young men who reported repeated binge drinking had higher systolic blood pressure and cholesterol levels than non-binge drinker...
A team of researchers at Ohio State University has developed a painless microneedle technology inspired by the mosquito's proboscis. The new design incorporates four key elements: a numbing agent, a serrated design, vibration during insertion, and a combination of soft and hard parts on the proboscis.
Researchers at the University of Maryland Baltimore County (UMBC) have developed a novel method to produce therapeutic proteins within two hours using human blood. The technique involves extracting cellular protein synthesis machinery from human blood and adding recombinant DNA to produce specific treatments.
A study published in Nature and Science of Sleep found that concurrent elevations of haemoglobin A1c, C-reactive protein, and erythropoietin in the blood may indicate obstructive sleep apnea. These biomarkers proved superior to standard screening methods, particularly in non-obese males.
D-transposition of the great arteries is a cyanotic congenital heart disease affecting 3-5% of CHDs, with surgical management evolving to anatomic repair. Clinicians must closely monitor patients through adulthood and beyond for long-term outcomes.
A new blood test identified biomarkers in maternal blood that accurately predicted gestational age and preterm delivery, which may help doctors assess pregnancies more effectively. The study's findings offer hope for preventing premature birth, a crisis affecting millions of babies worldwide each year.
A Stanford-led study developed a blood test detecting premature birth with 75-80% accuracy. The test also estimates gestational age, reducing infant mortality risk and improving prenatal care in low-resource settings.
A new study lengthens intervals between blood draws for stable warfarin patients, reducing frequency and discomfort. Researchers found that more than two-thirds of patients can wait longer than five weeks without needing a blood draw.
A new blood test using cardiac myosin-binding protein C (cMyC) can rapidly rule out heart attacks in more people than the standard troponin test, freeing up hospital bed space and resources. The test is sensitive enough to give an almost immediate diagnosis, which could save hundreds of thousands of pounds per UK hospital every year.
A decade-long study has shown that sulphonylurea tablets are a safe and effective treatment option for babies with neonatal diabetes, providing excellent blood sugar control over the long-term. The treatment has been hailed as a 'miracle cure' by patients and their families, offering improved quality of life.
A 69-year-old male patient was conscious during CPR after a cardiac arrest, despite efforts to restore a pulse and circulation. The study suggests that the high level of patient awareness was due to good peripheral and cerebral blood flow, but raises questions about proper sedation during resuscitation.
A study published in the European Society of Anaesthesiology and Intensive Care suggests that nail treatments do not impact digital pulse oximetry readings. Experimental results found no significant variation in blood oxygen saturation levels, even under different physiological conditions. The findings contradict widespread concern and...
Subarachnoid hemorrhage can disrupt brain signaling, leading to extreme constriction of blood vessels and energy deprivation. The 'negative ultraslow potential' is an electrophysiological correlate of infarction and tissue death due to inadequate blood supply.
New research reveals that high altitudes reduce heart function by decreasing blood volume and increasing lung pressure. The study's findings will improve our understanding of how the human body adapts to high-altitude environments, making exploration and tourism safer and facilitating exercise performance at high altitude.
Researchers are reevaluating lactate's role in metabolism and its potential as a treatment for various diseases. Lactate supplementation has been shown to speed recovery after injury or illness and is being explored as a tool to control blood sugar, fuel the brain, and manage inflammation.
Research reveals a significant rise in postpartum haemorrhage in Victoria, with one in five women experiencing primary blood loss after childbirth. The study highlights the need for improved monitoring and treatment protocols to address this concerning trend.
A new brain stimulation technique, dTMS, has shown promising results in reducing food cravings in obese patients. The study found that high-frequency dTMS significantly increased beta-endorphins levels, leading to a decrease in glucose and leptin levels, suggesting a potential safer alternative to treat obesity.
A study of 30,626 Danish patients found that anticoagulation therapy after stroke significantly reduced the risk of blood vessel-blocking clots. Patients with atrial fibrillation are at increased risk of ischemic stroke, and OAC can reduce this risk.
Researchers discovered a genetic mutation in troponin T that disrupts the heart's ability to increase pumping force when needed. This limits the heart's capacity to pump additional blood around the body, potentially leading to severe consequences for individuals with hypertrophic cardiomyopathy.
The updated 'Hour-1 Bundle' introduces five critical steps for treating sepsis immediately upon recognition, including measuring lactate levels, performing blood cultures, and administering broad-spectrum antibiotics. This revised bundle aims to further reduce mortality rates among patients with sepsis by beginning treatment promptly.
A Kaiser Permanente study found that patients with intermittently recurring atrial fibrillation who experience longer periods of abnormal heart rhythms are three times more likely to have strokes or blood clots. Continuous heart monitoring may help physicians identify high-risk patients and tailor treatments.
Researchers have discovered four separate lineages of green-blooded lizards, each with unique evolutionary history. The study suggests that high levels of biliverdin in these lizards may have adaptive value, potentially leading to new approaches to treating human diseases such as malaria.
The VTC Research Institute is developing a test to diagnose mild traumatic brain injury (mTBI), which can have long-term damage despite subtle or no physical signs. The test combines analysis of multiple biomarkers with imaging and cognitive tests.
A national trial has found that measuring electrical activity in the brain can predict a patient's response to an antidepressant, improving treatment accuracy. Researchers believe combining EEGs with blood and brain tests will lead to more effective treatments for depressed patients.
A 6-week CrossFit exercise programme improved blood sugar control and reduced heart disease risk in people with Type 2 diabetes. Participants showed significant improvements in insulin sensitivity and heart disease risk factors, even with shorter exercise sessions than traditional guidelines recommend.
Researchers discovered a protective protein activated by vitamin K is inactive and abundant in African-Americans on dialysis. High levels of the protein, matrix Gla protein (MGP), correlate with increased arterial stiffness and impaired endothelial function.
Researchers at Michigan State University have identified how MRSA absorbs human fatty acids to resist antimicrobials, providing a new target for developing more effective treatments. By inhibiting the cell membrane's ability to produce lipids, scientists may improve the efficacy of existing antibacterial agents like triclosan.
A new film, 'Voices from the Mine', sheds light on the human costs of artisanal diamond mining in Sierra Leone, where miners face poverty and hardship despite the industry's $250 million annual value. The film highlights the need for a more nuanced understanding of the diamond trade, particularly among consumers and policy makers.
A new biomarker, CKAP4, has been identified in patients with stage I lung cancer, offering a potential non-invasive diagnostic marker that could improve patient outcomes. The sensitivity of serum CKAP4 was found to be higher than current sero-diagnostic markers.
A new study uses the COstatus monitor to directly measure cardiac output in neonates, providing a more accurate and less invasive way to gauge heart function. The results show that cardiac output can be precisely measured in the first two weeks of life with no adverse events.
Researchers at UTA are investigating the biochemical mechanism of ovarian hormones regulating cholesterol balance in the blood, aiming to open up new therapeutic avenues for treating cardiovascular disease. The study may lead to preventive treatments and customized therapies.
Researchers at the University of Cincinnati discovered that female mosquitoes bite not only to get protein but also to quench their thirst during a drought. Dehydration prompted as many as 30 percent of female mosquitoes to seek a blood meal, increasing the risk of disease transmission.
Researchers found that mid-back muscle decline is associated with increased kyphosis curvature, but not low-back muscle decline. Targeted resistance exercises may help prevent kyphosis progression
A new study by University of Gothenburg researchers identifies a superior blood-based biomarker for assessing subtle brain injury after sports-related concussions. The protein neurofilament light (NfL) levels were found to correlate with the severity of concussion and the duration of post-concussive symptoms.
A new DNA method efficiently screens vampire bat blood meal and faecal samples to determine which domestic animals they feed on, while also assessing population structure. This technique may aid in preventing rabies exposure by identifying animal hosts at risk.
A new study finds nearly one in four blood bank supplies contain malaria parasites, putting children and pregnant women at risk. The lack of sensitive diagnostic technology exacerbates the issue, highlighting the need for better vigilance and screening practices to keep blood banks safe.
Research reveals vampire bats' reliance on their genome and microbiome for survival on a low-energy diet. The study shows that the bat's microbiome helps compensate for the lack of vitamins and fatty substances in their blood-based diet.
In a study on Baltimore neighborhoods, researchers found that mosquito bites vary by socioeconomic status, with rats being the primary blood meal source in lower-income areas. Humans and cats are also bitten, but proportionally more frequently in higher-income neighborhoods due to human behavior.
A new blood test has been developed to detect early indicators of Alzheimer's disease, measuring the relative amounts of pathological and healthy amyloid-beta forms in the blood. The test was found to reliably detect signs of the disease on average eight years before diagnosis, with an overall diagnostic accuracy of 86%.
A new blood test has been developed to predict tuberculosis (TB) development in high-risk individuals, such as those living with active TB, up to two years before its onset. The 'RISK4' signature measures the expression levels of four genes associated with inflammatory responses and shows improved accuracy compared to existing tests.
Researchers have identified genetic variants associated with type 2 diabetes and blood sugar levels in a large Chinese population study. The findings suggest that these variants can reduce gene activity, leading to elevated blood sugar levels. Further analysis is needed to understand the role of these variants in human insulin secretion.
A study from the University of Iowa found that pre-pregnant women with higher fitness levels had a 21% lower risk of developing gestational diabetes. Moderate physical activity, such as brisk walking, can help reduce this risk.
A follow-up study of infected but asymptomatic individuals reveals parasite levels drop quickly after infection onset. Despite low levels at day 28, the study suggests that these individuals pose a shorter transmission risk to communities aiming for malaria elimination.
The BIABooster device characterizes DNA in blood circulation with new precision and sensitivity, identifying promising signatures for cancer monitoring. It has been shown to detect DNA up to a concentration of 10 fg/μL with precisions of 20% and 3%.
A study by Michigan Medicine and Rutgers New Jersey Medical School found Flint childhood blood lead levels decreased from 11.8% in 2006 to 3.2% in 2016, with a historic low of 1.15 micrograms per deciliter in 2016. A random spike in blood lead levels was also observed between 2010 and 2011.
Researchers have identified a specific sugar found on aggressive breast cancer cells that can be used as a biomarker to detect high-risk patients. This discovery aims to improve screening for early-stage breast cancer patients, reducing unnecessary treatments such as chemotherapy or radiation.
The new instrument increases the sensitivity of optical mammography by up to 1000-fold, allowing for earlier detection of breast cancer. This advancement offers a safer and more gentle alternative to traditional X-ray imaging, which is often limited by patient age, weight, or other factors.
Researchers found that tuberculosis patients with lower blood concentrations of key medications are more likely to be contagious. This discovery highlights the need for routine checks and potentially increased dosages to control the spread of the disease.
Yogalakshmi Rajendran, an Assistant Professor at the University of California, San Francisco, received the fellowship for her clinical application of autologous blood products in regenerative dentistry and NIH-funded study on oral cavity microflora.
Researchers studying cavefish found that they can live healthy lives with high blood sugar levels, contrary to what is seen in humans. The fish have insulin resistance but no apparent harm from chronically elevated glucose levels.