A new device has been developed to reduce radiation exposure in nanoscale-level imaging of living cells, allowing for more accurate and undamaged images. This innovation enables the study of biological, chemical, and materials science samples in their near-native environments.
Researchers at the Alfred Wegener Institute found higher amounts of microplastic in arctic sea ice, with concentrations up to 12,000 particles per litre. The unique composition and layering of plastic particles suggest sources such as the Pacific Ocean's garbage patch and intensified shipping and fishing activities.
A large-scale study has revealed two gene variants linked to increased malaria risk and one variant that protects against other childhood diseases. The study found that the Sl2 mutation in the CR1 gene offers protection against cerebral malaria, but only if alpha-thalassaemia is not present.
Researchers found more than 200 attacks on healthcare in Syria in 2016, resulting in 112 health worker and 185 patient deaths. A new mobile reporting tool improved data collection accuracy, highlighting the need for consistent methods to quantify these attacks.
A study published in PLOS Biology found that exercise-induced appetite suppression is linked to the activation of temperature-sensitive TRPV1-like receptors in hypothalamic arcuate nucleus cells. These cells respond to heat and play a role in suppressing food intake in response to exercise.
New research finds that thinning forests due to wildfires can reduce water stress and save up to 17 billion gallons of water annually. This approach may help offset the costs of forest restoration, which could increase water flow from Sierra Nevada watersheds by as much as 10 percent.
Acute myeloid leukemia (AML) has a poor five-year survival rate of less than 20%. Researchers at the National University of Singapore identified a novel molecular pathway involving circadian clock gene SHARP1, which causes AML growth. Removing or reducing SHARP1 levels can stop leukemic cell growth.
A groundbreaking study by Case Western Reserve University estimates that exposure to domestic violence carries significant long-term consequences for children and society. The research found that the average cost to the national economy over a child's lifetime is nearly $50,000, including increased medical costs, violent crimes, and pr...
A study of 92 trials found that music significantly decreased anxiety and pain in surgical patients, with a reduction of 21 mm in anxiety and 10 mm in pain. The findings suggest guidelines for implementing music interventions during surgery can be created.
A recent study of 2.7 billion tweets confirms Twitter's echo chambers are real, with partisan users dominating networks and content endorsement. Bipartisan users who bridge the gap between opposing sides face a price in network position, community connections, and content endorsement.
Researchers found that mid-back muscle decline is associated with increased kyphosis curvature, but not low-back muscle decline. Targeted resistance exercises may help prevent kyphosis progression
Researchers at the National Institute of Genetics have elucidated a neuronal population essential for fear conditioning in zebrafish, revealing a functional equivalent of the amygdala in mammals. This discovery has significant implications for understanding fundamental neural circuits and their evolution.
Scientists have solved the puzzle of trans 1,3-butadiene's electronic-structural dynamics using ultrafast laser spectroscopy. The research reveals an ultrafast competition between ethylenelike and polyenelike dynamics in butadiene.
Researchers at Carnegie Mellon University used an inexpensive 3D printer to produce self-folding plastic objects that can be heated to assume predetermined shapes. The process utilizes a common printing defect, warpage, which is typically considered a problem with these printers.
Researchers estimate that airborne dust levels could increase by 10-30% due to drought conditions, resulting in a 20-130% rise in premature deaths and a 60-300% growth in hospitalizations. The US Southwest is projected to experience severe and persistent droughts by 2100, posing a substantial public health burden.
A new study found that nearly half of people with metabolically healthy obesity (MHO) developed metabolic syndrome within 10 years, increasing their risk for cardiovascular disease and diabetes. MHO is defined as a body mass index of more than 30 and two or fewer risk factors.
Researchers have developed a platform for 3-D printing food with customized texture and body absorption characteristics, enabling personalized nutrition. The technology has the potential to reduce food waste and meet the increasing demands of a growing world population.
A new study by UCL found that socio-political factors are the primary cause of conflict and displacement in East Africa, with climate change playing a significant but secondary role. The research suggests that stable governance, economic growth, and reduced population growth can help reduce conflict and displacement.
Research suggests that mental fatigue, rather than physical fatigue, has a significant impact on older adults' walking ability. Volunteers performed physically and mentally tiring tasks, with their gait speed and stride length decreasing significantly in those who reported more cognitive fatigue.
Researchers found that children's muscles are more fatigue-resistant and recover faster than those of untrained adults and even well-trained endurance athletes. This discovery may lead to better understanding of how our bodies change from childhood to adulthood and inform the development of athletic potential in children.
This study reveals that cybergossiping has a positive impact on adolescents' relationships, promoting social interaction and understanding. The researchers also found that addressing cybergossip in the classroom can help promote healthy virtual relationships and reduce risky behavior.
A new study reveals that similar-status F1 drivers are more prone to collide, especially when they are age-similar, performing well, and feeling safe. The research team found structural equivalence triggers antagonism among interactants, leading to increased conflict.
The University of Louisville will receive a five-year, $11.2 million federal grant to establish an interdisciplinary research program focused on the microbiome, inflammation, and disease development. Researchers will study various diseases, including inflammatory bowel disease, periodontitis, and neurological disorders.
Researchers identified age-related differences in breast tissue that contribute to increased risk of developing breast cancer in older women. The study found that accumulation of multipotent progenitor cells leads to defective luminal cells, which may be related to the increased susceptibility to breast cancer with age.
Researchers at Sanford Burnham Prebys Medical Discovery Institute discovered that PKC zeta deficiency promotes liver metastasis through the inactivation of enzyme ADAR2, leading to increased secretion of miR-200s. Treatment with a compound inhibiting miR-200s reduced liver metastasis in mice with colorectal cancer.
Researchers developed a model to predict genomic variation in Eucalyptus melliodora, allowing for more resilient reforestation efforts. The study identified broadly sourced seeds as an effective strategy to combat climate change, promoting the recovery of critically endangered tree species.
Researchers found that a defective protein in Huntington's disease disrupts the mTORC1 pathway, leading to cardiac problems. Adjusting this pathway improved heart function in experimental animals, offering new insights into the biology of the disease.
Increasing temperatures and mercury pollution shift female-to-male ratios in snapping turtles, favoring male offspring in agricultural habitats. Field experiments found that temperature profiles and soil moisture content influenced sex determination, while mercury levels correlated with the development of more male offspring.
Researchers discovered that baricitinib prevented graft-versus-host disease and even reversed established cases in mouse studies. The drug boosts immune cells to fight cancer while keeping donor T cells from attacking vital organs.
A new study suggests that a partial collapse of the Atlantic Meridional Overturning Circulation (AMOC) could lead to extreme warming in European summers. This phenomenon, known as the 'cold-ocean-warm-summer' feedback, is linked to atmospheric blocking and has been observed in recent record-breaking cold ocean temperatures.
Teens prioritize family as the most important factor in happiness, but many don't consider their own family a positive example. Researchers believe this may contribute to high divorce rates and unpreparedness for married life.
A global meta-analysis found that engaging in physical activity decreases the chance of developing depression in people of all ages and geographical regions. The study pooled data from over 250,000 individuals and found consistent evidence that higher levels of physical activity are protective against future depression.
A new RAND Corporation paper warns that AI's potential to encourage risky behavior and undermine strategic stability poses a significant threat to global security. Improved sensor technologies and the rise of first-strike capabilities could erode mutual assured destruction, making nuclear war more likely.
A common genetics study method called Mendelian randomization has been found to be distorted by a phenomenon called horizontal pleiotropy in nearly 50% of its studies. This distortion can lead to false positive causal relationships and affects the accuracy of drug discovery and disease management.
Researchers found that zinc deficiency can negatively affect egg cell division, viability, and quality, which could impact fertility. The study suggests that micronutrient availability during oocyte maturation is critical for successful fertilization.
A randomized clinical trial of 200 patients with PAD found that a home-based exercise program with a wearable activity monitor and telephone coaching did not improve walking endurance. The results suggest that traditional in-person exercise programs may be more effective in improving walking ability for this patient population.
Researchers find gamma delta T cells in fat play a crucial role in regulating body temperature and protecting against cold shock. These immune cells, known as gd T cells, help turn white fat into brown fat to generate heat, leading to potential weight loss therapies for obesity patients.
Doctors at the University of Illinois Hospital have cured seven adult patients with sickle cell disease using compatible donor stem cells. The new transplant protocol allows for half-matched donors, significantly increasing potential donors and improving treatment outcomes.
Scientists at EMBL Rome developed a light-sensitive chemical that selectively binds to nerve cells causing neuropathic pain, leading to pain relief. The method avoids targeting single molecules and shows promise for managing chronic pain in humans.
A large-scale international study found that 57% of kids' apps collect and share personal data with third parties without parental consent. Many apps, including popular ones like Disney's 'Where's My Water?' and Gameloft's 'Minion Rush', may be infringing US Children's Online Privacy Protection Act (COPPA) rules.
A new study by Northwestern University found that a home-based exercise program with wearable devices and telephone coaching did not improve walking ability in patients with peripheral artery disease. The researchers suggest that this approach may worsen pain for participants, limiting their activity levels.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that girls with recently diagnosed type 2 diabetes had a high rate of menstrual irregularities. Many of these girls also had high testosterone levels, suggesting PCOS as an underlying cause.
Researchers at University of Pennsylvania School of Medicine have identified five strategies to reduce unplanned acute care for cancer patients, including leveraging advanced big data analytics, team-based care, and early palliative care. These best practices aim to improve patient experience and reduce hospital utilization.
Researchers found patients in hospitals want to track their health data and partner with care teams. Patients are interested in using devices like Fitbits to manage chronic conditions but prefer collaborative approach.
Scientists propose a new model where a heavy layer of molten rock sits on top of the Moon's metal core, driving the dynamo and creating a strong magnetic field. This model explains the Moon's early strong magnetic field and its subsequent weakening.
Researchers at Wyss Institute for Biologically Inspired Engineering at Harvard developed a new genetic analysis technique that harnesses natural barcodes in human genomes. This allows for faster, cheaper, and simpler tracking of cell identities across experiments, enabling large pools of cells from multiple people to be analyzed.
Treating leg ulcers within two weeks improves healing rates by 12% compared to standard treatment, with a success rate of 85.6%. Early intervention helps patients recover quicker and reduces the risk of complications such as amputation.
A Danish-German research team has identified a novel long non-coding RNA, A-ROD, that enhances the production of specific proteins with involvement in cancer. The RNA functions as a lasso that brings transcription factors to specific sites in DNA to enhance gene expression.
A study from York University shows that cognitive behavioral therapy can significantly improve children's emotional regulation, including anxiety and other emotional challenges. The intervention, involving a computer program and family support, led to improved mental health outcomes in children with autism.
A recent study found that Veterans Health Administration (VHA) facilities have varying care practices for military veterans with chronic pain, leading to inconsistent rates of long-term opioid therapy. Facilities with a wider range of non-opioid treatment options had lower rates of opioid use among veterans.
A UCL-led study found that hospitals are more likely to diagnose dementia in patients who have been admitted for another reason. However, missed diagnoses persist, with one-third of people with dementia discharged without recognition, highlighting the need for better record-sharing and culturally appropriate assessments.
Purdue researchers have developed an online platform called the Social Media Analytics and Reporting Toolkit (SMART) that filters social media content according to key words and geographic regions. The tool is being used by first responders to analyze both live and historical data, helping them attend to certain areas faster.
A University of Oregon-led project found that high immune function during childhood is associated with significant growth reduction. Chronic exposure to parasitic worms was linked to reduced stature and lower-leg growth, highlighting the metabolic cost of a robust immune system.
Bariatric surgery induces changes in alpha cells to produce beneficial GLP-1, combating insulin resistance and islet dysfunction associated with type 2 diabetes. Researchers aim to develop a drug mimicking this effect, making surgery's benefits more accessible.
Researchers at Albert Einstein College of Medicine found that intense exercise reduces appetite by activating temperature-sensitive receptors in the hypothalamus, a region of the brain that regulates metabolism and weight. The study provides evidence that body temperature can act as a biological signal that regulates feeding behavior.
A study by Yale University researchers found that newspaper op-eds have a lasting impact on people's views, regardless of their political affiliation or initial stance. The study, which included experiments with the general public and elites, showed that op-eds can change minds on policy issues for a cost-effective estimated $0.50 to $...
Researchers have identified a new gene, ari-1, linked to aortic aneurysms in humans through a fruit fly study. The study found that mutations in the ari-1 gene disrupt mechanical sensing mechanisms in the body, leading to abnormal nuclei shapes and potentially contributing to the development of aortic aneurysms.
A fractal-shaped electrode design enhances charge delivery for smaller neural stimulation targets, potentially prolonging device lifespan and improving resolution. The new shape facilitates faster Faradaic charge transfer, resulting in more efficient energy use.
Researchers found that users consider personalized apps more trustworthy when consulted about store preferences, leading to better usability and engagement. Higher perceived transparency reduces privacy concerns and boosts user involvement.
A new study from Oregon State University-Cascades found that millennials are not getting the message about sun safety and the dangers of tanning. The research suggests that those with lower self-esteem and higher narcissism rates are more likely to exhibit addictive tanning behavior, driven by a desire for improved appearance.