Articles tagged with Blood
The VTX-1 Liquid Biopsy System is a commercial, automated instrument that isolates clinically relevant CTC populations directly from whole blood. It achieves high recovery rates of spiked breast and lung cancer cell lines, with purities as low as <100 white blood cells per mL of processed blood.
Scientists at the University of Birmingham and other institutions have identified 902 genes related to blood feeding and 478 genes linked to non-blood feeding in the mosquito Wyeomyia smithii. The goal is to isolate universal non-biting genes that could be manipulated to control vector-borne diseases.
A new high-sensitivity troponin (hsTn) assay can measure lower concentrations of troponin, allowing for earlier diagnosis of heart attacks. The test has shown a significant reduction in wait times for emergency department patients, as well as improved patient satisfaction and safety.
A novel deep-learning based hematological human aging clock predicts the biological age of individual patients with high accuracy. The model outperforms chronological age in predicting all-cause mortality, highlighting population-specific patterns of aging.
A two-year study in Milan found that providing parents with information and 'nudges' to donate cord blood increased collection rates significantly. The study used behavioral science techniques to encourage expectant mothers to donate their baby's cord blood.
Researchers developed a new approach to detecting the cause of intracerebral hemorrhage (ICH), the deadliest form of stroke. Combining a blood test with a brain scan can accurately spot cerebral amyloid angiopathy (CAA), a condition linked to ICH and increased risk of further strokes and dementia.
A new app developed by researchers at University of Utah Health aims to motivate type 2 diabetes patients to increase physical activity. The interactive simulation tool helps patients understand the impact of exercise on blood sugar levels, leading to increased motivation and plans for more exercise.
A new study found that exercising four to five times a week can improve maximum oxygen intake during exercise by 18% and elasticity of the left ventricular muscle of the heart by over 25%. The research suggests that beginning exercise in late middle age can help reverse damage to sedentary hearts.
Researchers found that people with Parkinson's disease had significantly lower caffeine levels in their blood, even if they consumed the same amount as those without the disease. The study suggests a simple test for early diagnosis could be developed using caffeine levels.
A study found that high doses of vitamin D significantly reduced arterial stiffness in a population with vitamin deficiency. The results suggest that vitamin D supplementation can be an effective treatment for improving cardiovascular health.
Researchers in Colorado study 200 people affected by AFFF contamination, collecting data on biological markers and health indicators to assess biopersistence and potential health impacts of PFASs. The study aims to provide a better understanding of the effects of long-term exposure to these chemicals.
Research suggests that women with heart disease are more vulnerable to the effects of mental stress, particularly in terms of constricted peripheral vessels leading to reduced blood supply. This increased risk is associated with a higher likelihood of heart-related events and death.
Researchers found that whole eggs stimulate greater post-workout muscle protein synthesis compared to egg whites. The study suggests that consuming protein in its natural matrix is more beneficial for muscles.
The new guidelines recommend a set of blood tests to diagnose patients with liver disease, including bilirubin, albumin, and liver enzymes. They also provide guidance on how to manage patients with abnormal test results, aiming to reduce unnecessary repeat testing for those unlikely to have significant liver disease.
Researchers discovered a genetic link between sulfur compounds and chronic bad breath in humans and genetically modified mice. The study found that people with the condition had mutations in the SELENBP1 gene and high levels of odor-causing chemicals in their blood, mirroring findings in mice with the same mutation.
Researchers have identified genetic differences between mosquitoes that prefer plants and those that consume blood. The study suggests that the shift from blood to plant-based diet may be driven by reduced risks of predation and stress associated with consuming blood meals.
Scientists at the University of Oregon have isolated blood-feeding and non-biting genes in mosquitoes, a breakthrough that could lead to female mosquitoes that no longer bite and spread diseases. The goal is to identify universal non-biting genes across multiple disease vectors.
Researchers infect rhesus macaques with Zika virus through mosquito bites, revealing similar infection patterns to human cases. The study helps understand Zika transmission routes and may aid in prevention and severity of disease.
A multicenter study shows that a personalized Survivorship Care Plan can significantly reduce patients' stress levels related to their cancer treatment. The study found that the intervention decreased distress over a 6-month period compared to those who did not receive the care plan. This innovative approach empowers transplant survivo...
A large clinical trial shows that clot-busting drugs do not prevent post-thrombotic syndrome, a complication that can cause chronic limb pain and swelling. The procedure did reduce the severity of the syndrome, but with an increased risk of major bleeding.
A recent study published in The Lancet found that the use of pencil-point atraumatic needles during lumbar punctures significantly reduces the occurrence of headaches and other complications. The research team analyzed data from over 30,000 patients across 29 countries, showing a more than 50% reduction in headaches and readmissions.
A study found that cerebral blood flow is altered in preterm newborns' brains, with key regions such as the insula and anterior cingulate cortex receiving decreased blood supply. This alteration may serve as an early warning sign of disturbed brain maturation.
A new therapeutic paradox targets thrombo-vascular complications in kidney disease by boosting a regulatory protein called STUB1, which interacts with tissue factor to trigger clotting. This approach may offer an alternative to standard heparin treatment while maintaining a balance between pro-clotting and anticoagulant factors.
A new NYU report reveals that the phase-out of Teflon-like coatings, which contain PFOA, has led to a significant decrease in low-birth weight babies and related brain damage. The study estimates that this shift has saved over $13 billion in healthcare costs and improved educational prospects for thousands of children.
A new study finds that children who don't drink tap water are more likely to have tooth decay, while those who do tend to have elevated blood lead levels. The study analyzed nearly 16,000 children and adolescents aged two to 19 years.
Researchers at Boston Children's Hospital have developed a soft robotic system that can provide isolated support to the right or left ventricle, addressing one-sided heart failure. The system combines rigid bracing with soft robotic actuators to help diseased heart chambers pump blood effectively.
A study found that women who underwent sleeve gastrectomy may need to limit their alcohol consumption due to faster absorption rates. The surgery speeds up the transfer of alcohol into the bloodstream, leading to higher blood alcohol levels and increased risk of binge drinking and associated health issues.
Research findings emphasize the importance of measuring and maintaining aerobic fitness to reduce CHD risk. Moderate to high levels of cardiorespiratory fitness provide significant protection against CHD death, regardless of blood TG:HDL ratio.
A new transcatheter implant has been shown to be safe and effective in treating diastolic heart failure by reducing blood backup in the lungs. The device, a dime-size interatrial shunt, diverted blood flow from high-pressure chambers to low-pressure ones, improving pulmonary capillary wedge pressure readings.
Researchers compared 11 measures of aging, including blood and chromosome tests, and found that none consistently predicted physical or cognitive changes. Telomere length and epigenetic clocks showed some promise but were less clearly linked to physiological outcomes.
Researchers found that long-term yerba mate supplementation reduced body weight and improved blood lipid levels, as well as insulin resistance in obese mice. The study suggests that yerba mate may be a safe and effective way to manage weight and related metabolic disorders.
Researchers at Tufts University will develop devices to improve the collection, storage and transport of blood samples in field settings, enhancing sample reliability for disease surveillance and diagnostics.
Researchers found that individuals with A, B, and AB blood types have an elevated risk of heart attacks during times of significant air pollution compared to those with O blood type. The study links increased risk of heart attack associated with small particulate pollution to increased risk for people with coronary artery disease.
A new study finds that a simple tool, Fuster-BEWAT score, can predict cardiovascular risk in healthy individuals using five health indicators: blood pressure, physical activity, body-mass index, fruit and vegetable intake, and smoking status. The Fuster-BEWAT score is as effective as the American Heart Association-recommended ICHS index.
A new blood test can accurately predict which patients are at risk of liver damage from paracetamol overdose, enabling targeted treatment and reducing hospital stays. The test detects three specific molecules associated with liver damage, allowing for earlier intervention and more effective care.
A new study found that the Fuster-BEWAT score accurately predicts cardiovascular risk in healthy individuals, even without blood analysis. The score uses five health indicators: blood pressure, physical activity, BMI, fruit and vegetable intake, and smoking status.
Researchers found that prolonged TV viewing increases the risk of developing venous thromboembolism, even in those who meet physical activity guidelines. The study suggests that incorporating physical activity into daily routines, such as walking or using a treadmill while watching TV, can help mitigate this risk.
A simple blood test for phosphatidylethanol (PEth) can accurately identify critically ill hospital patients who misuse alcohol. The test has been found to be 88.7% accurate in identifying participants with alcohol misuse, with a level of at least 250 ng/ml being a useful cut-point.
A study published in Neurology found that reduced heart blood flow may lead to lower blood flow in the brain's memory centers. The research suggests that mechanisms regulating blood flow become vulnerable with age, potentially leading to cognitive impairment.
A Stanford study found that mechanical heart valves are beneficial until age 70 for mitral valve replacement and until age 55 for aortic valve replacement. Researchers examined patient records from 142 hospitals in California between 1996 and 2013, resulting in the largest number of patients ever studied to examine this issue.
A new study found that treatment with tranexamic acid must be given within minutes of severe bleeding to improve survival by 70%. The World Health Organization has updated its recommendations for the use of tranexamic acid, calling for it to be made readily available in all health systems to reduce global deaths from severe bleeding.
Research found that eating fat at night leads to higher blood fat levels, a risk factor for heart disease and diabetes. The study's findings suggest ignoring the body's natural 24-hour cycle can harm health.
Researchers found that virtual reality significantly reduced patients' and parents' perception of acute pain, anxiety, and general distress during blood draw procedures. The study suggests that VR could act as a preventative intervention transforming the blood draw experience into a less distressing procedure.
The UK is struggling to find undiagnosed hepatitis C patients due to lack of awareness about deadly virus and new treatment drugs. Experts estimate that at least 100,000 people remain undiagnosed, threatening the country's goal to eliminate the disease by 2030.
Researchers developed a risk assessment system, HANDOC, to identify patients with streptococcal bacteria who need echocardiography for potential heart valve infection. The system showed good reliability in distinguishing high and low-risk patients.
A new study published in PLOS ONE demonstrates that Videssa Breast, a liquid biopsy test, can reliably rule out breast cancer in women with dense and non-dense breast tissue. With an over 99% negative predictive value, clinicians can confidently use the test to detect cancer in women with dense breasts.
A study of US military combat casualties in Afghanistan found that prehospital blood transfusions within minutes of injury or prior to hospitalization resulted in greater 24-hour and 30-day survival rates compared to delayed or no transfusion. Early transfusion also showed a reduced risk of death over 24 hours when administered up to 1...
A new study found that weight loss after bariatric surgery can lead to significant improvements in heart health, including a return to natural shape and function. The study also showed a decrease in ventricle size by 15.7 percent, reducing the risk of heart failure.
Research from Rice University found that individuals with depressive symptoms before a disaster experience increased inflammation, a major risk factor for heart disease. The study tracked participants' health markers after the 2005 Texas City petrochemical refinery explosion and found a significant increase in inflammatory markers.
A five-year study found that genetic testing can help tailor the warfarin dosage to individual patients undergoing joint replacement surgery, resulting in significant reductions in adverse side effects. The study showed a 75% decrease in major bleeding and a 15% decrease in blood clots.
Researchers discovered that mTORC1 is essential for VLDL-triglyceride production, controlling lipid synthesis and storage in the liver. The study suggests targeting mTORC1 to prevent non-alcoholic fatty liver disease and cardiovascular disease associated with obesity and diabetes.
A study published in Clinical Infectious Diseases defines the burden of hepatitis C virus infection in the Democratic Republic of Congo (DRC). Researchers developed a simple test using existing HIV testing equipment, identifying 1% of adults living in the DRC as potentially infected.
Researchers found mosquitoes make stealthy takeoffs with barely a push-off, instead relying on strong wing beats for lift. They can carry blood meals without issue, using sweeping wing movements to generate extra lift.
Newomics Inc.'s multinozzle emitter array (MEA) technology can screen for diseases or toxins in small volumes of biological samples, improving sensitivity and throughput. This technology is designed to work with mass spectrometers to measure the structure and concentration of molecules, enabling better medicines and diagnostics.
Researchers discover that well-fed mosquitoes use a softer take-off technique to evade detection, utilizing their long legs and high wingbeat frequency. This strategy allows them to minimize tactile detection without compromising on take-off speed.
A large observational study compared the safety of new anti-clotting drugs with warfarin. The results show that DOACs are not associated with a higher risk of major bleeding, similar to warfarin. This suggests that DOACs can be a viable alternative for treating serious blood clots.
Researchers found that blood pressure medication only restored normal vascular rhythms in larger vessels, leaving smallest ones unaffected. The study suggests that hypertension worsens age-related decline in microvascular function.
A new study published in The Lancet Diabetes & Endocrinology suggests that a diet rich in omega-6 polyunsaturated fats may significantly reduce the risk of developing type 2 diabetes. Researchers found that individuals with higher levels of linoleic acid, the major omega-6 fat, had a lower chance of developing type 2 diabetes.
Scientists at ETH Zurich have developed a method to monitor lipolysis in real-time by analyzing exhaled acetone during exercise. The new breath test can detect when the body starts burning fat, allowing athletes to optimize their training regimen.
Research reveals that oxytocin is ingested by intestinal villiated epithelial cells via RAGE receptors after gut closure. This mechanism enables oxytocin to be orally administered as a medication and/or nutrient supplement in milk, promoting social brain development and communication.