Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
A new study from the University of Eastern Finland found that high levels of omega-6 fatty acids in the blood are associated with a lower risk of premature death. The research also showed that this association is not limited to cardiovascular disease, but may also apply to other conditions such as diabetes.
Researchers found that participants on the 5:2 diet cleared triglyceride from a meal more efficiently than those on daily calorie restriction, reducing an important risk factor for cardiovascular disease. The study also showed a greater reduction in systolic blood pressure in participants on the 5:2 diet.
A study published by the British Heart Foundation found that premature hearts are less able to cope with exercise, leading to increased risk of heart failure. Researchers compared the heart function of adults born prematurely to those carried to term and discovered a significant difference in blood leaving the heart during exercise.
A study estimates that historical lead exposure may be responsible for 256,000 premature deaths from cardiovascular disease each year in the USA. The study found that low-level lead exposure increases the risk of premature death, especially from cardiovascular disease.
The MOMENTUM 3 clinical trial found that advanced heart-failure patients who received a centrifugal-flow circulatory pump had significantly lower rates of pump-related blood clots and stroke compared to those receiving an axial flow pump. Patients who received the centrifugal-flow pump also had fewer re-operations due to device malfunc...
A study from Umea University found that people who use moist snuff have significantly higher levels of protein cornulin in their blood. Lifestyle factors can influence background levels, and the researchers hope to find disease-detecting proteins in the future.
Research analysis of blood mediators in type 1 diabetes and kidney disease patients reveals 10 elevated proteins, with TNF-alpha family and IL-6 significantly impacting 40% of patients. This study suggests personalized medicine approach to target specific inflammatory mediators for effective treatment.
Researchers at Walter and Eliza Hall Institute have identified a unique molecular signature in the blood that could detect aggressive lung cancer and predict response to immunotherapy, offering new hope for patients with limited treatment options.
The American College of Physicians (ACP) recommends less intensive blood sugar control targets for most patients with type 2 diabetes, aiming for an A1C range of 7-8% rather than 6.5-7%. This approach prioritizes symptom management over intensive treatment to balance benefits and harms.
Physicians and biomedical engineers create patient-specific models to predict complications and optimize treatment decisions. The approach has led to improved patient outcomes, such as Bernice Belcher's successful open heart surgery.
Scientists at Martin-Luther-Universität Halle-Wittenberg create albumin-based gels, which could be used to produce drug-delivery implants. The gels' structure and properties were altered by modifying solution pH and temperature conditions.
The new edition includes quality management, reflecting the rapidly evolving field of bone marrow transplantation. The standards have been developed through international consensus and are recognized globally among transplantation professionals.
Researchers developed a method to obtain critical information about cardiac function using machines that help failing hearts circulate blood. The new approach may pave the way to self-contained mechanical circulatory support systems for patients suffering from cardiogenic shock after a heart attack.
A new study introduces a holistic 3D numerical simulation model of the human heart, taking into account the mutual interaction between blood flow and individual components. The model reveals complex effects of heart strings on the mitral valve, shedding light on potential strategies for preventing cardiac problems.
Researchers found the Asian tiger mosquito vanished from Palmyra Atoll following rat eradication, as humans became the sole host for mosquitoes to feed on. The study highlights a potential new approach to combatting mosquito-borne diseases by eradicating key hosts.
Researchers found a potential link between varicose veins and deep venous thrombosis, but more research is needed to confirm the association. The study also suggests that varicose veins may be associated with an increased risk of peripheral artery disease and pulmonary embolism.
A new study reveals that nearly one in four PICC placements are made for less than five days, resulting in complications such as blocked lines, infections, blood clots, and serious kidney problems. This raises concerns about the risks associated with short-term IV device use.
A recent study published in the Journal of Thrombosis and Thrombolysis found that prolonged TV viewing increases the risk of venous thromboembolism, a potentially fatal condition. The research, which analyzed data from over 15,000 Americans, suggests that even regular exercise is not enough to offset the risks of sedentary behavior.
Research reveals that high blood pressure impairs the body's response to hypoxia, limiting oxygen delivery to vital organs and tissues. Middle-aged men with high blood pressure were found to have reduced blood flow to the brain and leg muscles during low-oxygen conditions.
The vampire bat's unique blood-based diet requires specific genetic and microbial adaptations, including enhanced iron assimilation and immunity, to tackle nutritional and non-nutritional challenges posed by blood meals. The findings suggest that the bats' microbiome plays a crucial role in their defense against viral infections.
A recent study has found that people over 65 with chronic kidney disease and atrial fibrillation are at increased risk of stroke when taking blood thinners. The researchers estimate that half a million UK adults fall into this category, highlighting the need for cautious prescribing practices.
A ketone ester supplement has been shown to lower blood sugar levels in healthy individuals by reducing spikes in sugar consumption. The study used a single drink containing 75 grams of sugar and found that the ketone drink reduced the blood sugar spike compared to a placebo.
A study published in PLOS Medicine found that perfluoroalkyl substances (PFASs) may interfere with human body weight regulation, leading to greater weight gain after dieting. Higher blood levels of PFASs were linked with lower resting metabolic rates, which can result in slower metabolism and increased calorie burn.
Researchers found a clear link between low arachidonic acid levels and retinopathy of prematurity (ROP) in extremely premature babies. Providing the children with arachidonic acid may help reduce the risk of ROP and minimize blindness.
A new study found that lower sodium levels in the blood, known as hyponatremia, are related to declines in cognitive function with advancing age. Slightly lower serum sodium levels were associated with increased risk of cognitive impairment and decline over time, while high serum sodium was also linked to cognitive decline.
A new blood test, T2Candida Panel, detects candidemia with high accuracy, reducing time to diagnosis by nearly two days. The test shows promise in speeding up treatment and potentially improving patient survival rates.
A study published in Neurology suggests that strokes can compromise the blood-ocular barrier, causing gadolinium to leak into the eye. This phenomenon could potentially provide valuable information about stroke severity and guide treatment.
A study published in JAMA found that patients with a patent foramen ovale (PFO) are at increased risk of stroke after non-cardiac surgery. The researchers analyzed data from over 150,000 patients and found that approximately 3.2% of those with a PFO experienced a stroke within 30 days, compared to 0.5% without one.
Research suggests that migraine is associated with an increased risk of cardiovascular diseases in both men and women. The study found a positive association between migraine and heart attack, stroke, blood clots, and irregular heart rate, particularly among women.
The blood test measures a specific peptide to inform scientists of Alzheimer's disease presence with 90% accuracy. It has the potential to accelerate therapeutic strategies development by speeding up patient selection for new drug trials.
Researchers found that tranexamic acid prevents blood loss after vaginal births and postpartum hemorrhage among women with operative vaginal deliveries or episiotomies. The study, presented at the Society for Maternal-Fetal Medicine's annual meeting, suggests TXA should be considered for women at risk of PPH.
A recent study found that blood clots in the lungs are extremely rare in patients who experience fainting and visit the emergency department. The researchers analyzed data from over 1.6 million adults across four countries, revealing a surprisingly low frequency of pulmonary embolism among those with syncope.
A new study of 5,000 older people in the UK found that those with diabetes experience steeper rates of cognitive decline compared to those with normal blood sugar control. The study suggests that efforts to delay diabetes onset and control blood sugar levels may prevent subsequent progression of brain function decline.
A study by MUSC Health found that using a mechanical ISDD and educating staff led to a nearly four-fold decrease in contaminated blood cultures. This reduction resulted in improved accurate diagnoses, decreased antibiotic use, and cost savings.
Researchers developed stable, self-disrupting microbubbles to carry oxygen in the blood, reducing the risk of embolism. The microbubbles were shown to increase survival rates in rodents with cardiac arrest, providing a potential lifesaving treatment.
A study found that pediatric cancer patients' microbiome diversity can predict the risk of developing blood infections, suggesting a link between gut health and bloodstream infections. The researchers argue that prevention and treatment strategies may depend on the source of infection, rather than relying solely on central line hygiene.
The VTX-1 Liquid Biopsy System is a commercial, automated instrument that isolates clinically relevant CTC populations directly from whole blood. It achieves high recovery rates of spiked breast and lung cancer cell lines, with purities as low as <100 white blood cells per mL of processed blood.
Scientists at the University of Birmingham and other institutions have identified 902 genes related to blood feeding and 478 genes linked to non-blood feeding in the mosquito Wyeomyia smithii. The goal is to isolate universal non-biting genes that could be manipulated to control vector-borne diseases.
A new high-sensitivity troponin (hsTn) assay can measure lower concentrations of troponin, allowing for earlier diagnosis of heart attacks. The test has shown a significant reduction in wait times for emergency department patients, as well as improved patient satisfaction and safety.
A novel deep-learning based hematological human aging clock predicts the biological age of individual patients with high accuracy. The model outperforms chronological age in predicting all-cause mortality, highlighting population-specific patterns of aging.
A two-year study in Milan found that providing parents with information and 'nudges' to donate cord blood increased collection rates significantly. The study used behavioral science techniques to encourage expectant mothers to donate their baby's cord blood.
Researchers developed a new approach to detecting the cause of intracerebral hemorrhage (ICH), the deadliest form of stroke. Combining a blood test with a brain scan can accurately spot cerebral amyloid angiopathy (CAA), a condition linked to ICH and increased risk of further strokes and dementia.
A new app developed by researchers at University of Utah Health aims to motivate type 2 diabetes patients to increase physical activity. The interactive simulation tool helps patients understand the impact of exercise on blood sugar levels, leading to increased motivation and plans for more exercise.
A new study found that exercising four to five times a week can improve maximum oxygen intake during exercise by 18% and elasticity of the left ventricular muscle of the heart by over 25%. The research suggests that beginning exercise in late middle age can help reverse damage to sedentary hearts.
Researchers found that people with Parkinson's disease had significantly lower caffeine levels in their blood, even if they consumed the same amount as those without the disease. The study suggests a simple test for early diagnosis could be developed using caffeine levels.
A study found that high doses of vitamin D significantly reduced arterial stiffness in a population with vitamin deficiency. The results suggest that vitamin D supplementation can be an effective treatment for improving cardiovascular health.
Researchers in Colorado study 200 people affected by AFFF contamination, collecting data on biological markers and health indicators to assess biopersistence and potential health impacts of PFASs. The study aims to provide a better understanding of the effects of long-term exposure to these chemicals.
Research suggests that women with heart disease are more vulnerable to the effects of mental stress, particularly in terms of constricted peripheral vessels leading to reduced blood supply. This increased risk is associated with a higher likelihood of heart-related events and death.
Researchers found that whole eggs stimulate greater post-workout muscle protein synthesis compared to egg whites. The study suggests that consuming protein in its natural matrix is more beneficial for muscles.
The new guidelines recommend a set of blood tests to diagnose patients with liver disease, including bilirubin, albumin, and liver enzymes. They also provide guidance on how to manage patients with abnormal test results, aiming to reduce unnecessary repeat testing for those unlikely to have significant liver disease.
Researchers discovered a genetic link between sulfur compounds and chronic bad breath in humans and genetically modified mice. The study found that people with the condition had mutations in the SELENBP1 gene and high levels of odor-causing chemicals in their blood, mirroring findings in mice with the same mutation.
Researchers have identified genetic differences between mosquitoes that prefer plants and those that consume blood. The study suggests that the shift from blood to plant-based diet may be driven by reduced risks of predation and stress associated with consuming blood meals.
Scientists at the University of Oregon have isolated blood-feeding and non-biting genes in mosquitoes, a breakthrough that could lead to female mosquitoes that no longer bite and spread diseases. The goal is to identify universal non-biting genes across multiple disease vectors.
Researchers infect rhesus macaques with Zika virus through mosquito bites, revealing similar infection patterns to human cases. The study helps understand Zika transmission routes and may aid in prevention and severity of disease.
A multicenter study shows that a personalized Survivorship Care Plan can significantly reduce patients' stress levels related to their cancer treatment. The study found that the intervention decreased distress over a 6-month period compared to those who did not receive the care plan. This innovative approach empowers transplant survivo...
A large clinical trial shows that clot-busting drugs do not prevent post-thrombotic syndrome, a complication that can cause chronic limb pain and swelling. The procedure did reduce the severity of the syndrome, but with an increased risk of major bleeding.
A recent study published in The Lancet found that the use of pencil-point atraumatic needles during lumbar punctures significantly reduces the occurrence of headaches and other complications. The research team analyzed data from over 30,000 patients across 29 countries, showing a more than 50% reduction in headaches and readmissions.
A study found that cerebral blood flow is altered in preterm newborns' brains, with key regions such as the insula and anterior cingulate cortex receiving decreased blood supply. This alteration may serve as an early warning sign of disturbed brain maturation.
A new therapeutic paradox targets thrombo-vascular complications in kidney disease by boosting a regulatory protein called STUB1, which interacts with tissue factor to trigger clotting. This approach may offer an alternative to standard heparin treatment while maintaining a balance between pro-clotting and anticoagulant factors.
A new NYU report reveals that the phase-out of Teflon-like coatings, which contain PFOA, has led to a significant decrease in low-birth weight babies and related brain damage. The study estimates that this shift has saved over $13 billion in healthcare costs and improved educational prospects for thousands of children.