Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
A recent CARBS study showed that salacia extract reduces appetite and manages blood sugar levels by improving glycemic indices and gut hormones in healthy overweight/obese individuals. The proprietary extract, OmniLean, also reduces spikes in blood sugar and hunger pangs.
Peter Vitiello receives NIH grant to investigate oxygen-sensitive molecules influencing lung growth in premature infants. The research aims to reduce the burden of lasting lung disease, which can have life-long effects.
A new study found that at least 30-45% of athletes surveyed at top events acknowledged using banned doping techniques, while official biological tests only detected 0.5-3.6% of cases. The study used a randomized response method to ensure anonymity and honesty from respondents.
Researchers have found that bacterial cell wall constituents can cause abnormal clotting, leading to inflammation in Type 2 diabetes. A new treatment option involves using LPS-binding protein (LBP) to reverse this process, offering a new approach to treating the disease.
A new study has confirmed the safety and efficacy of a rapid algorithm to rule-out and rule-in myocardial infarction. The algorithm uses high-sensitivity cardiac troponin blood concentrations to diagnose patients with acute chest pain, allowing for quicker triage and early initiation of evidence-based therapy.
Researchers found that extremely high HDL levels are associated with a higher mortality rate than normal levels. Men with extremely high levels had a 106% higher mortality rate, while women had a 68% higher mortality rate. The study suggests that the focus on HDL as an important health indicator may need to be revised.
Researchers used a molecular adsorbent recirculating system (MARS) to provide time for healing or transplant in patients with severe acute liver failure. The study found improved survival rates and recovery of liver function in patients who received MARS therapy.
Researchers found that certain gut bacteria, such as Bacteroides and Clostridium, can predict brain metabolites like serotonin and myo-inositol, which are altered in individuals with autism. The study suggests a potential mechanism by which the gut microbiome communicates with the brain through cortisol.
A new study suggests that clinical signs, such as gastrointestinal problems and septic arthritis, are better indicators of mortality in neonatal calves with diarrhea than blood pH levels. The research found that these clinical signs were significant determinants of mortality, while blood pH levels were only a predictor when they droppe...
Researchers identified genetically targetable alterations in 66% of patients with cancer of unknown primary (CUP), a rare disease. The study used circulating tumor DNA in blood samples to detect these alterations, which could be targeted using existing FDA-approved drugs or therapies currently under investigation.
A yearlong study found that well-designed online education can decrease nonadministration rates of prescribed blood thinners to prevent venous thromboembolism. Nurses who completed an interactive education module showed a greater reduction in non-administration rates compared to those who received traditional voice-over instruction.
A new blood test can detect miniscule amounts of cancer DNA released into the blood, allowing for rapid detection of genetic mutations. This test has the potential to be personalized to recognize mutations unique to individual cancers.
A single-center study in Brazil found Zika virus infection associated with a diverse spectrum of serious neurologic syndromes, including Guillain-Barré syndrome and encephalitis. The study suggests serologic and molecular testing as an alternative diagnostic strategy in developing countries.
Researchers developed a test that detects Zika virus presence in blood in minutes, using gold nanorods on paper. The test relies on an immune response caused by the virus and doesn't require refrigeration, making it suitable for resource-limited settings.
A new study introduces a finger prick test for patients with rheumatoid arthritis and other autoimmune conditions taking adalimumab, enabling easy monitoring of drug levels without full blood draws. This method simplifies therapeutic drug monitoring, potentially benefiting patient care.
A new portable platform enables sensitive and rapid diagnostic testing in resource-limited settings, detecting telltale markers of disease as accurately as the most sensitive tests on the market. The D4 assay can identify a disease biomarker in as few as 15 minutes.
Researchers studied lizard venom to discover novel compounds with potential in treating stroke and deep-vein thrombosis. The study identified selective action on fibrinogen chains, a targeted approach successful for snake venom treatments.
A study published in the Journal of Clinical Investigation reveals that genetic abnormalities contribute to thiazide-induced hyponatremia, a condition causing low sodium levels. Researchers identified patients with this side effect who exhibited persistent subtle differences in blood and urine tests even after medication was stopped.
Researchers at the University of Cincinnati developed a novel device that can stimulate sweat glands on a small patch of skin, allowing for non-invasive biomarker testing. The device can predict sweat amounts, which is essential for understanding hormone or chemical measurements.
Researchers identified a cluster of immunoresolvents in blood that activate immune cells, enhancing the immune system's ability to fight bacterial infections. This new profiling procedure has potential applications in distinguishing between cancerous and healthy tissue.
Researchers at Stanford University School of Medicine have identified biomarkers associated with chronic fatigue syndrome severity by analyzing 17 immune-system signaling proteins. These findings suggest that inflammation is a powerful driver of the disease and may lead to improved diagnosis and treatment options.
The program will train staff at 20 health centers to offer group visits for diabetes patients, partnering with Care Message to implement a text messaging system. The goal is to consolidate services into one visit, provide education, and social support to help patients manage their blood sugar levels.
Scientists at UAlberta and McGill University have discovered a direct link between calcium and cholesterol, finding that a lack of calcium can hide cholesterol from the cell's machinery. This discovery could pave the way for new treatments for high blood cholesterol and heart disease.
A genetic predisposition to higher blood calcium levels is associated with an increased risk of coronary artery disease and heart attack. The study used mendelian randomization to examine the association between serum calcium levels and CAD, finding a link between the two.
Researchers found that memantine significantly reduced blood levels of neuron-specific enolase, a marker of neuronal damage, in patients with moderate TBI. The study also showed marked improvements in Glasgow Coma Scale scores on day 3, indicating potential therapeutic benefits.
Researchers have developed a blood test that can detect amyloid beta plaques in the brain, a key characteristic of Alzheimer's disease. The test measures levels of three different amyloid subtypes and has been shown to be highly accurate in identifying individuals with altered levels of amyloid in their brains.
A new saliva test developed by Johns Hopkins researchers matches the performance of a widely used blood test for diagnosing hepatitis E virus infection. The test has the potential to ease and speed up research into the disease, which affects an estimated 20 million people worldwide each year.
Researchers at University at Buffalo successfully tested a pre-hospital intervention that raises blood pressure in simulated trauma victims experiencing blood loss. Face cooling was shown to increase and maintain blood pressure during the simulation.
Researchers found elevated levels of two brain injury markers, neurofilament light chain and tau, in active professional fighters compared to retired fighters or non-fighters. These markers may signify permanent traumatic brain injury with long-term consequences.
Researchers at ETH Zurich developed a soft artificial heart made from silicone that mimics the human heart's form and function. The device lasts only 3,000 beats but paves the way for future improvements in artificial hearts.
A new therapy, idarucizumab, has been shown to rapidly reverse the effects of the blood thinner dabigatran in patients with life-threatening bleeding or emergency surgery needs. The study found that idarucizumab was able to stop bleeding within 2.5 hours and allow surgery to begin at a median of 1.6 hours after administration.
Forensic scientists at Nagoya University have successfully extracted human DNA from mosquitoes' stomachs and amplified it using PCR techniques. The team found that human DNA remained viable in mosquito blood for up to two days after feeding, providing a new tool for crime scene investigators.
Researchers discovered that sea spiders use gut peristalsis to move blood and oxygen throughout their bodies, not hearts. This unique system allows for efficient gas transport and highlights the diversity of solutions in animal physiology.
A new circular RNA marker has been identified in blood and lung tissue, associated with increased cell proliferation, migration, and invasion. High expression of this marker may improve lung cancer screening and detection at late stages.
Researchers at NIST have measured the vapor pressure of delta-9 tetrahydrocannabinol (THC), a fundamental property for developing accurate marijuana breathalyzers. The study uses PLOT-cryo technology to capture and analyze THC molecules, providing crucial groundwork for manufacturers.
A recent analysis of US dialysis facility data found that central venous catheters are associated with the most bloodstream infections in hemodialysis patients. Staphylococcus aureus was the most commonly isolated pathogen, with 40% of isolates resistant to antibiotic methicillin.
A team of scientists is using a combination of satellite and ground data to identify monkey populations that have declined through hunting. This approach combines indicators such as human activity zones, mosquito-derived DNA, animal sound recordings, and detections of other species found when monkeys are present.
Broccoli extract containing sulforaphane has been shown to lower blood sugar levels in patients with type-2 diabetes, targeting the liver's elevated glucose production and offering a mild side-effect profile.
Researchers at North Carolina State University have developed a new surgical tool using low-frequency intravascular ultrasound to break down blood clots. The tool breaks down clots into fine particles, reducing the need for high doses of blood thinners and potentially lowering treatment time.
A phase III clinical trial showed that combining lesinurad with febuxostat was more effective at lowering blood urate levels than febuxostat alone. The combination group achieved target urate levels in significantly more patients over 12 months.
A new blood test has been identified to predict the onset and track the progression of Huntington's disease. The test measures neurofilament levels in the blood, which increase throughout the course of the disease, even in carriers of the genetic mutation.
Researchers found that delayed meal times significantly affect blood sugar levels, with later meals causing a delay of over 5 hours in internal rhythms. The study suggests that timed meals could be beneficial for individuals with circadian rhythm disorders.
Research on mango consumption found potential benefits for metabolic disorders and inflammation, with improved blood pressure and gut health observed in human studies. The superfruit's galloyl derivatives showed anti-inflammatory activities and altered the gut microbiota and metabolism in lean and obese subjects.
A Michigan State University study has found that Charlie Kimball's optimized blood sugar levels and physiological monitoring help him capture top-5 finishes at the Indianapolis 500. The research also enabled Kimball to compete equally with other drivers, despite having Type 1 diabetes.
Chronic anabolic steroid use can lead to reduced heart function, including impaired pumping capacity and increased blood pressure. The study found strong associations between lifetime duration of illicit anabolic steroid use and plaque build-up in coronary arteries, highlighting the critical need for clinicians to monitor this population.
Researchers developed a 'good heart' muffin to help reduce the risk of heart disease through soluble fibre, meeting food standard guidelines for cholesterol-lowering properties. The muffins contain three grams of beta glucans, a healthy ingredient found in oats and cereals.
Researchers found correlations between blood levels of omega-3 fatty acids and fluid intelligence in healthy elderly adults, suggesting a potential role for dietary intake of these nutrients. The studies also linked the balance of omega-3 and omega-6 fatty acids to memory preservation and brain structure.
The DAWN trial shows that mechanical thrombectomy with medical therapy improves functional independence and decreases post-stroke disability in selected patients. Patients treated with the retrieval system had a 35% better outcome at 90 days compared to those who received medication alone.
Research led by University of Queensland scientist Associate Professor Bryan Fry reveals that brown snake venom attacks the nervous system in young snakes and circulatory system in older ones. This transformation allows the venom to become more potent and deadly, causing internal bleeding and death in humans.
A new study combines traditional CHA2DS2-VASc risk score with the Intermountain Mortality Risk Score to provide more accurate evaluations of atrial fibrillation patients' individual risks. This allows for better decision-making regarding blood thinners use, taking into account both clinical and biological factors.
Researchers have found a link between elevated beta-2 microglobulin levels and an increased risk of ischemic stroke in women. The study, conducted on over 900 participants, suggests that this protein may serve as a marker for inflammation and could potentially help identify people at higher risk of stroke.
A diet high in fruit, vegetables, and whole grains, but low in salt, sugary drinks, and red meat, is associated with a lower risk of gout. The DASH diet has been found to reduce blood pressure and uric acid levels, suggesting it may also lower gout risk.
A new study reveals that cerebral veins play a crucial role in regulating the brain's blood flow by storing and releasing blood throughout the cardiac cycle. This finding has significant implications for understanding diseases such as vascular dementia and normal pressure hydrocephalus.
A meta-analysis of prospective studies reveals that individuals with non-O blood groups (A, B, AB) are at a higher risk of heart attacks and overall cardiovascular mortality. The study found a 9% increased risk of coronary events and cardiovascular mortality in non-O blood group carriers compared to O blood group carriers.
A large Danish cohort study found that antibiotic use is associated with lower enterolignan concentrations in the blood, especially for women. The study suggests that antibiotics can negatively affect intestinal bacteria's ability to metabolize plant lignans into enterolignans.
Researchers discovered a positive relationship between exercise and vitamin D levels in reducing cardiovascular disease risks. The study found that exercising regularly boosted vitamin D stores, while adequate vitamin D levels also protected against heart attacks and strokes.
Routine blood tests are wasteful and potentially damaging, argue experts in The BMJ. They highlight the need for clinicians to rethink what counts as 'routine' when ordering laboratory tests.
Studies reveal that genes involved in immune regulation are linked to brain thickness and memory functions, particularly emotional experiences. A specific gene variant is also associated with increased activity in regions of the brain important for traumatic memories.
A new study suggests that applying an ice bag to the face could help prevent a sudden drop in blood pressure after blood loss, potentially saving lives among first responders. The technique was tested on healthy volunteers and showed promising results.
A research team solved the century-old mystery of Blood Falls by using radar technology to detect brine feeding the famous red waterfall. They discovered that liquid water can persist inside extremely cold glaciers, challenging previous thought on this phenomenon.