Articles tagged with Blood
A new accelerated diagnostic protocol, HEART Pathway, is effective in identifying low-risk ED patients with acute chest pain who can be safely sent home without hospitalization or comprehensive cardiac testing. The study found a 6% reduction in hospitalizations and significant decreases in median length of stay and use of stress testing.
A study by University of Pennsylvania researchers identified a rare example where being older improves tissue function, leading to reduced scar formation. The key factor is a compound called stromal cell-derived-factor-1 (SDF1), which is secreted in the bloodstream and is more abundant in younger individuals.
Researchers at UNC will investigate the epidemiology of Zika virus in pregnancy and its effects on infant neurodevelopment. The team will follow infants exposed to Zika in Nicaragua and test new diagnostic protocols to understand the virus's impact.
Colorado State University chemists are developing biologically friendly coatings to mitigate blood-device interactions in extracorporeal life support systems. These advancements aim to eliminate the need for blood thinners, reducing side effects and improving patient outcomes.
Researchers found that immediate compression therapy significantly reduced the risk of residual vein occlusion and post thrombotic syndrome in patients with DVT. The study suggests that starting compression therapy within 24 hours of diagnosis can prevent debilitating complications.
A blood test for microRNAs may help predict the likelihood of disease in dairy cows and improve animal welfare. This approach is already being applied to human disease diagnosis.
Researchers aim to develop and evaluate non-contrast based imaging methods to diagnose peripheral arterial disease without relying on gadolinium-based contrast agents. The proposed techniques have high applicability to other medical procedures, including venography and vessel wall imaging.
Researchers at Penn State are developing a new generation of blood pumps that use computational methods to predict clot formation and design safer devices. This could enable earlier intervention for patients with congestive heart failure, reducing recovery time and improving outcomes.
Researchers are developing portable sensors that can detect toxic metals like manganese in a single drop of blood. The sensors will enable faster and cheaper research as well as rapid detection of neurotoxins affecting cognitive development and neuromotor function.
A novel, paper-based method detects metabolite levels in blood using a bioluminescent sensor protein, measuring compounds like phenylalanine in minutes. The approach shows promise for point-of-care monitoring of diseases and injuries, potentially leading to faster diagnosis and management.
Researchers at Northwestern University developed a simple blood test called TimeSignature that can identify the body's precise internal time clock. The test measures gene expression markers and can be taken any time of day, allowing for more accurate diagnosis and treatment of diseases such as heart disease, diabetes, and Alzheimer's.
A new study published in the American Journal of Respiratory and Critical Care Medicine found that New York State's sepsis reporting mandate led to improved care and reduced mortality rates for critically ill patients. Patients who received standardized treatment protocols had shorter hospital stays and lower mortality rates.
A new lab-on-a-chip device developed by KU Leuven researchers can detect infections and viruses in blood with high accuracy, making it ideal for diagnosing people in developing countries. The device is simple, cheap to produce, and can be activated with a finger touch, allowing anyone to use it.
Sherpas' unique physiological adaptations to high altitude may help improve oxygen delivery in critically ill patients. By increasing blood flow and delivering oxygen to tissues, Sherpas thrive at low oxygen environments, offering a potential alternative to traditional high oxygen content strategies.
The National Heart Lung and Blood Institute will award $20 million to four academic centers over five years, with UC San Diego receiving $5 million. The program aims to correct the lack of attention given to glycans in biomedical research and train 18 early-career glycoscientists.
A study found that a specific E. coli strain from retail poultry products is causing urinary tract infections in people, with nearly 80% of meat samples and 72% of patient cultures positive for the bacteria. The research suggests that cooking poultry thoroughly and handling it carefully are crucial to prevent foodborne illnesses.
Researchers reduced household lead levels and found significant reductions in dust lead levels, especially among black children. However, the intervention did not result in significant neurobehavioral improvements, such as improved IQ or behavior. The study suggests that eliminating residential lead exposure may be necessary to fully p...
A new study found that using oral anticoagulants for 45 days after hospital discharge reduced the rate of non-fatal blood clots in medically ill patients. The trial, MARINER, showed no increase in major bleeding risk while offering protection against non-fatal blood clots.
A new study suggests that performing simple leg exercises while lying down can help prevent impairment of blood vessel function caused by a sedentary lifestyle. The research found that even a brief period of inactivity reduced the ability to rapidly increase blood flow to the lower legs.
A blood test can predict which patients with diffuse large B cell lymphoma are likely to respond positively to initial therapy. Researchers tracked circulating tumor DNA levels in 217 patients and found a correlation between rapid decline and improved outcome.
A blood test using Kidney-injury-molecule-1 (KIM-1) can predict clear cell kidney cancer risk and survival up to five years before diagnosis, with higher levels associated with poorer outcomes. The test substantially improves accuracy in predicting kidney cancer risk.
A new blood test can quickly detect early signs of liver disease in dogs, enabling prompt treatment and reducing the need for invasive biopsies. The test is based on insights from human patients and has been successfully tested on 250 dogs.
Researchers will develop a risk calculator using biomarkers and statistical modeling to predict blood clot formation in cancer patients. The goal is to identify patients at high risk and treat them proactively with blood thinners.
A new diagnostic test could help distinguish Kawasaki Disease from other conditions, enabling earlier diagnosis and treatment. The test targets a specific pattern of host gene expression in whole blood.
A Dartmouth study found that Arctic mosquito populations depend on aquatic habitats and blood meal availability. The research indicates that female mosquitoes carrying eggs were most abundant near ponds in areas frequented by animals.
Research led by LSU Health found that hypoxia decreases Protein S, a natural anticoagulant, increasing the risk of potentially life-threatening blood clots. The study identified the gene regulatory mechanism controlling PS production in response to oxygen levels.
A recent study found that just two weeks of inactivity can hasten the onset of Type 2 diabetes and elevate blood sugar levels among pre-diabetic patients. The study's findings suggest that seniors who experience periods of physical inactivity are more likely to suffer harmful consequences to their overall health.
Researchers from UNIGE have developed a portable device called TBIcheck that analyzes proteins in the blood to diagnose mild traumatic brain injury. The device can detect four biomarkers associated with brain injuries, including H-FABP, Interleukin-10, S100B, and GFAP.
A study found people with depression have lower blood levels of acetyl-L-carnitine than healthy individuals. The findings suggest a potential new class of antidepressants could be developed to treat severe or treatment-resistant depression.
Patients who underwent donor transplants in childhood have a higher risk of dying prematurely compared to the general population. The main causes of death were infection and chronic graft-vs-host disease, with patients' primary disease also contributing to their mortality.
A new Tel Aviv University study suggests that an intravenous injection of a potent enzyme can reduce inflammation and scarring that prevent neuronal regeneration after spinal cord injury. The treatment aims to lower levels of glutamate, released in toxic quantities after trauma, to moderate the damage and enable neuronal cells to survive.
Researchers have identified four biomarkers, including a new chemical called verruculotoxin, that may predict signs of first-trimester stillbirth. By analyzing maternal blood, scientists can develop tools to screen for preventable illnesses affecting both women and children.
A new blood test, Banyan Brain Trauma Indicator, has been approved to help diagnose traumatic brain injuries. The test detects two brain proteins in the blood after a head injury and can predict the presence of an intracranial injury on a head CT scan.
Research by UConn microbiologists found that tiny amounts of antibiotics in chicken blood can encourage bacterial resistance. The study used leeches as a perfect test case and discovered that low levels of ciprofloxacin in poultry blood were selecting for antibiotic-resistant Aeromonas bacteria.
Researchers found that proteins in saliva reflect high blood sugar levels in young patients with type 1 diabetes, allowing for early prediction of complications. A potential new preventive treatment has been identified using gene database searching.
Research found that invisible stool blood is associated with a heightened risk of death from bowel cancer, as well as circulatory, respiratory, digestive, and hormone diseases. A positive faecal occult blood test result was linked to an 8-fold increased risk of bowel cancer mortality.
Researchers found that lysophosphatidic acid levels increase after traumatic brain injury, particularly in areas associated with cell death and axonal injury. Elevated LPA may serve as a biomarker for TBI through blood testing, providing a prognostic indicator of injury and outcome.
An observational study published in the BMJ Open journal found a strong association between an unhealthy blood fat profile before pregnancy and lower fertility rates. Women with high cholesterol, triglycerides, and low HDL cholesterol were more likely to have only one or no children.
Researchers at UC Riverside are exploring a hormone-targeting approach to control mosquito reproduction, which is linked to blood feeding. The goal is to develop innovative vector control methods and potentially reduce the spread of diseases transmitted by mosquitoes.
Researchers at Lund University have found a direct link between the gastrointestinal flora and lung disease in the setting of blood transfusions. The composition of the gut bacteria drives the pathogenic immune response in the lungs during Transfusion Related Acute Lung Injury (TRALI), a complication that can be fatal.
A breakthrough discovery by RMIT University could enable early detection of Type 1 diabetes in newborns, potentially delaying or preventing the onset of the disease. The collaboration combines lab-on-a-chip technologies with biomarker detection to identify early loss of beta cells.
The University of Hong Kong research team developed a C-reactive protein sensor integrated onto a medical catheter, enabling real-time CRP sensing with a thickness less than one micrometer. This allows doctors to take immediate actions, speeding up testing and curing of inflammation by 30 times.
A study suggests that abnormal metabolism of three essential amino acids may contribute to the development of type 2 diabetes in women who have a history of gestational diabetes. Women with a history of gestational diabetes had higher levels of branched-chain amino acids in their blood, regardless of their dietary intake.
A recent study published in the European Respiratory Journal found that obstructive sleep apnea is associated with changes to brain structure similar to those seen in early-stage dementia. The study suggests that screening for OSA and treating it could help prevent dementia in older adults.
A new microfluidics technique has been developed to construct microchannels with efficient gas exchange, potentially delivering nearly a third of the oxygen needed by preterm newborns. The design uses both sides of the membrane for gas exchange and is more effective than previous single-sided counterparts.
A new blood test can determine an individual's internal clock, allowing for personalized drug administration and more effective treatment. The test identifies biomarkers that reliably report internal time, differentiating early and late types.
A Portsmouth researcher is developing a mathematical model to speed up the delivery of life-saving blood to victims of disasters, reducing blood wastage and loss of life. The model will inform venue and location for temporary blood donation centres, transportation routes, and quantities delivered.
A new observational study reveals that apixaban is potentially safer than warfarin in dialysis patients with atrial fibrillation, with a significantly lower risk of major bleeding. The study found that patients on apixaban had a 30% lower risk of major bleeding without a difference in stroke rate.
A new study published in Journal of the American Heart Association found that young adults who frequently binge drink are more likely to have risk factors for cardiovascular disease. The research revealed that young men who reported repeated binge drinking had higher systolic blood pressure and cholesterol levels than non-binge drinker...
A team of researchers at Ohio State University has developed a painless microneedle technology inspired by the mosquito's proboscis. The new design incorporates four key elements: a numbing agent, a serrated design, vibration during insertion, and a combination of soft and hard parts on the proboscis.
Researchers at the University of Maryland Baltimore County (UMBC) have developed a novel method to produce therapeutic proteins within two hours using human blood. The technique involves extracting cellular protein synthesis machinery from human blood and adding recombinant DNA to produce specific treatments.
A study published in Nature and Science of Sleep found that concurrent elevations of haemoglobin A1c, C-reactive protein, and erythropoietin in the blood may indicate obstructive sleep apnea. These biomarkers proved superior to standard screening methods, particularly in non-obese males.
D-transposition of the great arteries is a cyanotic congenital heart disease affecting 3-5% of CHDs, with surgical management evolving to anatomic repair. Clinicians must closely monitor patients through adulthood and beyond for long-term outcomes.
A new blood test identified biomarkers in maternal blood that accurately predicted gestational age and preterm delivery, which may help doctors assess pregnancies more effectively. The study's findings offer hope for preventing premature birth, a crisis affecting millions of babies worldwide each year.
A Stanford-led study developed a blood test detecting premature birth with 75-80% accuracy. The test also estimates gestational age, reducing infant mortality risk and improving prenatal care in low-resource settings.
A new study lengthens intervals between blood draws for stable warfarin patients, reducing frequency and discomfort. Researchers found that more than two-thirds of patients can wait longer than five weeks without needing a blood draw.
A new blood test using cardiac myosin-binding protein C (cMyC) can rapidly rule out heart attacks in more people than the standard troponin test, freeing up hospital bed space and resources. The test is sensitive enough to give an almost immediate diagnosis, which could save hundreds of thousands of pounds per UK hospital every year.
A decade-long study has shown that sulphonylurea tablets are a safe and effective treatment option for babies with neonatal diabetes, providing excellent blood sugar control over the long-term. The treatment has been hailed as a 'miracle cure' by patients and their families, offering improved quality of life.
A 69-year-old male patient was conscious during CPR after a cardiac arrest, despite efforts to restore a pulse and circulation. The study suggests that the high level of patient awareness was due to good peripheral and cerebral blood flow, but raises questions about proper sedation during resuscitation.
A study published in the European Society of Anaesthesiology and Intensive Care suggests that nail treatments do not impact digital pulse oximetry readings. Experimental results found no significant variation in blood oxygen saturation levels, even under different physiological conditions. The findings contradict widespread concern and...