Articles tagged with Blood
The National Heart Lung and Blood Institute will award $20 million to four academic centers over five years, with UC San Diego receiving $5 million. The program aims to correct the lack of attention given to glycans in biomedical research and train 18 early-career glycoscientists.
A study found that a specific E. coli strain from retail poultry products is causing urinary tract infections in people, with nearly 80% of meat samples and 72% of patient cultures positive for the bacteria. The research suggests that cooking poultry thoroughly and handling it carefully are crucial to prevent foodborne illnesses.
Researchers reduced household lead levels and found significant reductions in dust lead levels, especially among black children. However, the intervention did not result in significant neurobehavioral improvements, such as improved IQ or behavior. The study suggests that eliminating residential lead exposure may be necessary to fully p...
A new study found that using oral anticoagulants for 45 days after hospital discharge reduced the rate of non-fatal blood clots in medically ill patients. The trial, MARINER, showed no increase in major bleeding risk while offering protection against non-fatal blood clots.
A new study suggests that performing simple leg exercises while lying down can help prevent impairment of blood vessel function caused by a sedentary lifestyle. The research found that even a brief period of inactivity reduced the ability to rapidly increase blood flow to the lower legs.
A blood test can predict which patients with diffuse large B cell lymphoma are likely to respond positively to initial therapy. Researchers tracked circulating tumor DNA levels in 217 patients and found a correlation between rapid decline and improved outcome.
A blood test using Kidney-injury-molecule-1 (KIM-1) can predict clear cell kidney cancer risk and survival up to five years before diagnosis, with higher levels associated with poorer outcomes. The test substantially improves accuracy in predicting kidney cancer risk.
A new blood test can quickly detect early signs of liver disease in dogs, enabling prompt treatment and reducing the need for invasive biopsies. The test is based on insights from human patients and has been successfully tested on 250 dogs.
Researchers will develop a risk calculator using biomarkers and statistical modeling to predict blood clot formation in cancer patients. The goal is to identify patients at high risk and treat them proactively with blood thinners.
A new diagnostic test could help distinguish Kawasaki Disease from other conditions, enabling earlier diagnosis and treatment. The test targets a specific pattern of host gene expression in whole blood.
A Dartmouth study found that Arctic mosquito populations depend on aquatic habitats and blood meal availability. The research indicates that female mosquitoes carrying eggs were most abundant near ponds in areas frequented by animals.
Research led by LSU Health found that hypoxia decreases Protein S, a natural anticoagulant, increasing the risk of potentially life-threatening blood clots. The study identified the gene regulatory mechanism controlling PS production in response to oxygen levels.
A recent study found that just two weeks of inactivity can hasten the onset of Type 2 diabetes and elevate blood sugar levels among pre-diabetic patients. The study's findings suggest that seniors who experience periods of physical inactivity are more likely to suffer harmful consequences to their overall health.
Researchers from UNIGE have developed a portable device called TBIcheck that analyzes proteins in the blood to diagnose mild traumatic brain injury. The device can detect four biomarkers associated with brain injuries, including H-FABP, Interleukin-10, S100B, and GFAP.
A study found people with depression have lower blood levels of acetyl-L-carnitine than healthy individuals. The findings suggest a potential new class of antidepressants could be developed to treat severe or treatment-resistant depression.
Patients who underwent donor transplants in childhood have a higher risk of dying prematurely compared to the general population. The main causes of death were infection and chronic graft-vs-host disease, with patients' primary disease also contributing to their mortality.
A new Tel Aviv University study suggests that an intravenous injection of a potent enzyme can reduce inflammation and scarring that prevent neuronal regeneration after spinal cord injury. The treatment aims to lower levels of glutamate, released in toxic quantities after trauma, to moderate the damage and enable neuronal cells to survive.
Researchers have identified four biomarkers, including a new chemical called verruculotoxin, that may predict signs of first-trimester stillbirth. By analyzing maternal blood, scientists can develop tools to screen for preventable illnesses affecting both women and children.
A new blood test, Banyan Brain Trauma Indicator, has been approved to help diagnose traumatic brain injuries. The test detects two brain proteins in the blood after a head injury and can predict the presence of an intracranial injury on a head CT scan.
Research by UConn microbiologists found that tiny amounts of antibiotics in chicken blood can encourage bacterial resistance. The study used leeches as a perfect test case and discovered that low levels of ciprofloxacin in poultry blood were selecting for antibiotic-resistant Aeromonas bacteria.
Researchers found that proteins in saliva reflect high blood sugar levels in young patients with type 1 diabetes, allowing for early prediction of complications. A potential new preventive treatment has been identified using gene database searching.
Research found that invisible stool blood is associated with a heightened risk of death from bowel cancer, as well as circulatory, respiratory, digestive, and hormone diseases. A positive faecal occult blood test result was linked to an 8-fold increased risk of bowel cancer mortality.
Researchers found that lysophosphatidic acid levels increase after traumatic brain injury, particularly in areas associated with cell death and axonal injury. Elevated LPA may serve as a biomarker for TBI through blood testing, providing a prognostic indicator of injury and outcome.
An observational study published in the BMJ Open journal found a strong association between an unhealthy blood fat profile before pregnancy and lower fertility rates. Women with high cholesterol, triglycerides, and low HDL cholesterol were more likely to have only one or no children.
Researchers at UC Riverside are exploring a hormone-targeting approach to control mosquito reproduction, which is linked to blood feeding. The goal is to develop innovative vector control methods and potentially reduce the spread of diseases transmitted by mosquitoes.
Researchers at Lund University have found a direct link between the gastrointestinal flora and lung disease in the setting of blood transfusions. The composition of the gut bacteria drives the pathogenic immune response in the lungs during Transfusion Related Acute Lung Injury (TRALI), a complication that can be fatal.
A breakthrough discovery by RMIT University could enable early detection of Type 1 diabetes in newborns, potentially delaying or preventing the onset of the disease. The collaboration combines lab-on-a-chip technologies with biomarker detection to identify early loss of beta cells.
The University of Hong Kong research team developed a C-reactive protein sensor integrated onto a medical catheter, enabling real-time CRP sensing with a thickness less than one micrometer. This allows doctors to take immediate actions, speeding up testing and curing of inflammation by 30 times.
A study suggests that abnormal metabolism of three essential amino acids may contribute to the development of type 2 diabetes in women who have a history of gestational diabetes. Women with a history of gestational diabetes had higher levels of branched-chain amino acids in their blood, regardless of their dietary intake.
A recent study published in the European Respiratory Journal found that obstructive sleep apnea is associated with changes to brain structure similar to those seen in early-stage dementia. The study suggests that screening for OSA and treating it could help prevent dementia in older adults.
A new microfluidics technique has been developed to construct microchannels with efficient gas exchange, potentially delivering nearly a third of the oxygen needed by preterm newborns. The design uses both sides of the membrane for gas exchange and is more effective than previous single-sided counterparts.
A new blood test can determine an individual's internal clock, allowing for personalized drug administration and more effective treatment. The test identifies biomarkers that reliably report internal time, differentiating early and late types.
A Portsmouth researcher is developing a mathematical model to speed up the delivery of life-saving blood to victims of disasters, reducing blood wastage and loss of life. The model will inform venue and location for temporary blood donation centres, transportation routes, and quantities delivered.
A new observational study reveals that apixaban is potentially safer than warfarin in dialysis patients with atrial fibrillation, with a significantly lower risk of major bleeding. The study found that patients on apixaban had a 30% lower risk of major bleeding without a difference in stroke rate.
A new study published in Journal of the American Heart Association found that young adults who frequently binge drink are more likely to have risk factors for cardiovascular disease. The research revealed that young men who reported repeated binge drinking had higher systolic blood pressure and cholesterol levels than non-binge drinker...
A team of researchers at Ohio State University has developed a painless microneedle technology inspired by the mosquito's proboscis. The new design incorporates four key elements: a numbing agent, a serrated design, vibration during insertion, and a combination of soft and hard parts on the proboscis.
Researchers at the University of Maryland Baltimore County (UMBC) have developed a novel method to produce therapeutic proteins within two hours using human blood. The technique involves extracting cellular protein synthesis machinery from human blood and adding recombinant DNA to produce specific treatments.
A study published in Nature and Science of Sleep found that concurrent elevations of haemoglobin A1c, C-reactive protein, and erythropoietin in the blood may indicate obstructive sleep apnea. These biomarkers proved superior to standard screening methods, particularly in non-obese males.
D-transposition of the great arteries is a cyanotic congenital heart disease affecting 3-5% of CHDs, with surgical management evolving to anatomic repair. Clinicians must closely monitor patients through adulthood and beyond for long-term outcomes.
A new blood test identified biomarkers in maternal blood that accurately predicted gestational age and preterm delivery, which may help doctors assess pregnancies more effectively. The study's findings offer hope for preventing premature birth, a crisis affecting millions of babies worldwide each year.
A Stanford-led study developed a blood test detecting premature birth with 75-80% accuracy. The test also estimates gestational age, reducing infant mortality risk and improving prenatal care in low-resource settings.
A new study lengthens intervals between blood draws for stable warfarin patients, reducing frequency and discomfort. Researchers found that more than two-thirds of patients can wait longer than five weeks without needing a blood draw.
A new blood test using cardiac myosin-binding protein C (cMyC) can rapidly rule out heart attacks in more people than the standard troponin test, freeing up hospital bed space and resources. The test is sensitive enough to give an almost immediate diagnosis, which could save hundreds of thousands of pounds per UK hospital every year.
A decade-long study has shown that sulphonylurea tablets are a safe and effective treatment option for babies with neonatal diabetes, providing excellent blood sugar control over the long-term. The treatment has been hailed as a 'miracle cure' by patients and their families, offering improved quality of life.
A 69-year-old male patient was conscious during CPR after a cardiac arrest, despite efforts to restore a pulse and circulation. The study suggests that the high level of patient awareness was due to good peripheral and cerebral blood flow, but raises questions about proper sedation during resuscitation.
A study published in the European Society of Anaesthesiology and Intensive Care suggests that nail treatments do not impact digital pulse oximetry readings. Experimental results found no significant variation in blood oxygen saturation levels, even under different physiological conditions. The findings contradict widespread concern and...
New research reveals that high altitudes reduce heart function by decreasing blood volume and increasing lung pressure. The study's findings will improve our understanding of how the human body adapts to high-altitude environments, making exploration and tourism safer and facilitating exercise performance at high altitude.
Subarachnoid hemorrhage can disrupt brain signaling, leading to extreme constriction of blood vessels and energy deprivation. The 'negative ultraslow potential' is an electrophysiological correlate of infarction and tissue death due to inadequate blood supply.
Researchers are reevaluating lactate's role in metabolism and its potential as a treatment for various diseases. Lactate supplementation has been shown to speed recovery after injury or illness and is being explored as a tool to control blood sugar, fuel the brain, and manage inflammation.
Research reveals a significant rise in postpartum haemorrhage in Victoria, with one in five women experiencing primary blood loss after childbirth. The study highlights the need for improved monitoring and treatment protocols to address this concerning trend.
A new brain stimulation technique, dTMS, has shown promising results in reducing food cravings in obese patients. The study found that high-frequency dTMS significantly increased beta-endorphins levels, leading to a decrease in glucose and leptin levels, suggesting a potential safer alternative to treat obesity.
A study of 30,626 Danish patients found that anticoagulation therapy after stroke significantly reduced the risk of blood vessel-blocking clots. Patients with atrial fibrillation are at increased risk of ischemic stroke, and OAC can reduce this risk.
Researchers discovered a genetic mutation in troponin T that disrupts the heart's ability to increase pumping force when needed. This limits the heart's capacity to pump additional blood around the body, potentially leading to severe consequences for individuals with hypertrophic cardiomyopathy.
The updated 'Hour-1 Bundle' introduces five critical steps for treating sepsis immediately upon recognition, including measuring lactate levels, performing blood cultures, and administering broad-spectrum antibiotics. This revised bundle aims to further reduce mortality rates among patients with sepsis by beginning treatment promptly.
Researchers have discovered four separate lineages of green-blooded lizards, each with unique evolutionary history. The study suggests that high levels of biliverdin in these lizards may have adaptive value, potentially leading to new approaches to treating human diseases such as malaria.
The VTC Research Institute is developing a test to diagnose mild traumatic brain injury (mTBI), which can have long-term damage despite subtle or no physical signs. The test combines analysis of multiple biomarkers with imaging and cognitive tests.
A Kaiser Permanente study found that patients with intermittently recurring atrial fibrillation who experience longer periods of abnormal heart rhythms are three times more likely to have strokes or blood clots. Continuous heart monitoring may help physicians identify high-risk patients and tailor treatments.
A national trial has found that measuring electrical activity in the brain can predict a patient's response to an antidepressant, improving treatment accuracy. Researchers believe combining EEGs with blood and brain tests will lead to more effective treatments for depressed patients.
A 6-week CrossFit exercise programme improved blood sugar control and reduced heart disease risk in people with Type 2 diabetes. Participants showed significant improvements in insulin sensitivity and heart disease risk factors, even with shorter exercise sessions than traditional guidelines recommend.
Researchers discovered a protective protein activated by vitamin K is inactive and abundant in African-Americans on dialysis. High levels of the protein, matrix Gla protein (MGP), correlate with increased arterial stiffness and impaired endothelial function.