Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
A study found that women living in green spaces had a later age at menopause, with an average age of 51.7 years compared to 50.3 years in areas with little green space. Lower cortisol levels and reduced risk of depression may contribute to this association.
Scientists have made a breakthrough in understanding the rapid reproduction of the malaria parasite by identifying crucial molecules involved in cell division. This discovery could pave the way for developing novel therapeutic strategies against the disease.
A study published in Nature Communications reveals a major link between protein FHR4 and age-related macular degeneration, affecting 1.5 million people in the UK alone. The findings show that higher levels of FHR4 in the blood increase the risk of AMD by activating part of the immune system.
A new protein called factor H-related protein 4 (FHR-4) has been linked to age-related macular degeneration. Higher levels of FHR-4 in the blood may indicate increased risk of developing the disease, which affects over 1.5 million people in the UK.
A new robot created by Rutgers University has performed as well or better than humans in blood sampling, providing quick results and reducing complications. The device includes an ultrasound-guided robot that draws blood from veins, and could be used in various medical procedures to improve patient outcomes.
Researchers at Oxford University have found a protein called Plexin D1 that detects disturbances in blood flow and triggers inflammation and plaque formation, leading to serious health problems. The discovery offers new hope for developing treatments to block plaques before they form.
A study published in the British Journal of Dermatology found that higher mercury levels in the blood are associated with an increased prevalence of non-melanoma skin cancer. Participants with high total or methyl mercury levels had nearly double or 1.7 times greater odds of non-melanoma skin cancer, respectively.
A UCLA-led study found that six blood proteins can be used to gauge a person's risk for cerebral small vessel disease, which affects an estimated 11 million older adults in the U.S. The test correlates with white matter changes in the brain and provides a more quantitative scale for evaluating the disease.
Researchers developed a novel gas imaging system to visualize and measure gases released through the skin in real-time. The system uses VOCs present in circulating blood to diagnose metabolic disorders, genetic diseases, and cancer.
A new study by the University of Alberta found that pregnant women with elevated fasting blood sugar levels are at a higher risk of complications, including large babies, high blood pressure, and preterm births. Despite receiving diabetes drug treatments, these women were more likely to experience adverse outcomes.
A study published in Radiology found that patients with abdominal aortic aneurysms and blood clots on the aorta wall experience faster growth and increased rupture risk. The researchers suggest adjusting imaging follow-up schedules for these patients to reduce the risk of rupture.
A groundbreaking study published in PNAS used a multi-modal precision health platform to identify adults at risk of key health conditions, including cancer, heart disease, and neurological disorders. The study found that integrating whole-genome sequencing with advanced imaging and blood metabolites led to clinically significant findin...
Overweight adults who followed the Mediterranean, Intermittent Fasting and Paleo diets experienced modest weight loss (2-4kg) and clinically significant improvements in blood pressure. The Mediterranean diet also improved blood sugar levels, while the fasting diet led to slightly more weight loss.
Researchers developed a total-body PET/CT scanner with advanced reconstruction techniques to capture radiotracer transport in humans at 100 ms timescales. This approach offers clear images of cardiac blood pool changes throughout the cardiac cycle, enabling real-time motion tracking and neural activity analysis.
A study published in PLOS Neglected Tropical Diseases found that typhoid prevalence is likely higher than estimated due to missed blood cultures, with patients more likely to have cultures if older, feverish or suspected urinary tract infection.
Researchers have analyzed the polychromy of the Pachacamac idol using non-invasive techniques, revealing that red is not blood but mercury from cinnabar. The study also confirms the idol's age as around 731 AD, with local ritual importance before Inca rule.
A pilot study of 25 donor-recipient pairs reveals young stem cell donors have previously undetected and potentially disease-causing mutations in their blood stem cells. These mutations, linked to post-transplant complications, are more prevalent in young donors than thought.
Researchers at UT Southwestern Medical Center found a significant association between malignant left ventricular hypertrophy and an increased risk of heart failure among black individuals. The study, published in the journal Circulation, suggests that early intervention can be beneficial in preventing future risk.
Researchers have identified a mechanism that contributes to clot formation in mechanical heart valves. By modifying the valve's design, turbulent vortices can be eliminated, reducing the risk of blood clots and strokes. This breakthrough could lead to life without blood thinners for thousands of people with artificial heart valves.
The American grasshopper's circulatory system responds dramatically to changes in body position due to gravity, affecting blood and air distribution. Physiological compensation mechanisms similar to vertebrates suggest an ancient, widespread response to gravitational forces.
Grasshoppers adjust their cardiovascular and respiratory activity in response to gravity, with mechanisms similar to those found in vertebrates. The study reveals that insects have functional valves and can control fluid flow to prevent blood pooling in the brain.
Researchers have developed a superhydrophobic material that repels blood and promotes fast clotting, making it ideal for use as a bandage. The material's antibacterial effect also reduces the risk of infection when changing bandages.
A new study published in Blood Advances reveals that patients with metabolic syndrome are more likely to experience recurrent blood clots. The study analyzed 151,054 patients diagnosed with deep vein thrombosis and found that those with comorbid metabolic syndrome conditions had a higher risk of VTE recurrence.
A study published in PLOS ONE found that using altruistic terminology may not be effective in targeting non-donors. Instead, focusing on a sense of social obligation could lead to better cut-through rates. The researchers also discovered that blood donors tend to have higher primary prosocial characteristics like altruism and empathy.
Researchers at Children's National Hospital developed a direct measurement technique for cardiac output in newborns, utilizing changes in blood velocity after injecting saline. The study used ultrasound dilution and reported promising results, with potential implications for personalized care of critically ill newborns.
A new blood test has been developed to measure microRNAs in children's blood, which can indicate sufficient or inadequate sleep. This test may provide a more reliable metric for assessing sleep hygiene and predicting susceptibility to various health conditions.
A preliminary study found that losing a night of sleep increases tau levels in blood by an average 17-percent compared to a good night of sleep. Higher levels of tau may reflect clearance of proteins from the brain or elevated levels in the brain.
A study by Uppsala University found that sleeping deprivation for just one night increased tau protein levels in the blood of young, healthy men. This accumulation can start decades before Alzheimer's symptoms appear.
A new study reveals that peripherally inserted central catheters (PICCs) increase the risk of blood clots and bloodstream infections in children. Children with a prior history of VTE, larger caliber catheters, or leukemia are more susceptible to these complications.
Researchers found that a ketone monoester drink can help participants with Type 2 diabetes and pre-diabetes better control their blood sugar levels without insulin changes. The study's lead author notes that while ketone supplements are not a magic bullet, they may be another strategy for managing the disease.
A team of researchers discovered a case of stagnant blood flow resulting in a clot in the internal jugular vein of an astronaut on the International Space Station. The study found that anticoagulation therapy was effective in reducing the size of the clot, but not eliminating it entirely.
A US astronaut on the International Space Station developed a deep vein thrombosis, prompting UNC expert Stephan Moll to consult and develop a treatment plan. Moll advised on using Enoxaparin and Apixaban to effectively treat the blood clot, which was successfully managed over 90 days.
A review article published in The New England Journal of Medicine suggests that intermittent fasting can improve blood sugar regulation, increase resistance to stress, and suppress inflammation. Studies have shown that this adaptation may trigger a slower metabolic process, which can lead to weight loss and reduced belly fat.
A study by McMaster University researchers found that levels of NT-proBNP, a common cardiac blood test, can predict cardiac and vascular complications after non-cardiac surgery. The test may help doctors identify patients at risk and inform treatment decisions.
A genetic risk score can identify individuals at a 3-fold increased risk of developing ischaemic stroke, a devastating condition. This scoring system may require more intensive preventive measures than current guidelines recommend.
A new study found that over 24 routine blood tests are affected by childhood obesity, including liver function tests and inflammation markers. This discovery could help doctors better interpret test results and provide more accurate diagnoses.
Researchers used lipidomics and machine learning to identify a blood lipid profile linked to type 2 diabetes risk, which improved prediction over traditional methods. Lifestyle factors such as diet and physical activity also played a role in modulating the blood lipid profile.
A new review study published in the American Journal of Lifestyle Medicine finds that egg-industry funded research tends to skew findings, leading to a neutralized image of eggs as a cholesterol-raising product. Over 85% of studies showed unfavorable effects on blood cholesterol levels.
University of Guelph researchers have discovered that cortisol, a key stress hormone, accumulates in fish scales slowly and remains there for weeks. This allows scientists to gauge long-term stress levels without invasive blood tests.
A large study published in the New England Journal of Medicine found that high doses of vitamin D do not reduce mortality or improve non-fatal outcomes in critically ill patients. The Vitamin D to Improve Outcomes by Leveraging Early Treatment (VIOLET) study included over 200 researchers and showed no difference in mortality rates, hos...
A new study by Columbia University researchers suggests that a diet high in refined carbohydrates, particularly added sugars, may be partly to blame for insomnia. Women who consumed more vegetables and whole fruits were less likely to develop problems with insomnia.
Researchers have found a causal link between high blood triglycerides and chronic inflammation, leading to kidney damage and vascular disease. A diet low in fat can significantly extend the life expectancy of patients with diabetes or high blood pressure.
Researchers discovered a link between uremic solutes and Aryl Hydrocarbon Receptor (AHR) activation in CKD patients. This finding may lead to new clinical blood tests and medication development targeting AHR inhibitors for treating CKD complications.
Researchers found that beta-blockers increase the risk of hospitalizations for heart failure among patients with 'stiff heart' heart failure, characterized by a normal squeeze but impaired relaxation of the heart muscle. Beta-blocker use was associated with a 74% higher risk of hospitalizations in this patient population.
A new approach to interpreting D-dimer blood tests can help rule out pulmonary embolism and reduce the need for CT scans, freeing up resources and reducing radiation exposure. The study found that a higher-than-usual D-dimer level can be considered a negative result in patients with low probability of having a pulmonary embolism.
Scientists are testing a magnetically-actuated fluidic valve to reduce bleeding in trauma patients. The system uses an injectable magnetorheological suspension and externally placed magnets to create an obstruction, halting blood loss and stabilizing blood pressure. This could potentially extend survival time by at least 30 minutes.
Researchers identified kynurenine and indoxyl sulfate as key culprits in generating clot formation in cancer patients via AHR signaling. These metabolites can be measured in the blood to predict risk of deep vein thrombosis, and their inhibition may lead to future drug development.
A Mayo Clinic-led study found that people with inflammatory bowel disease, Type 1 diabetes or blood clots may be at increased risk of developing rheumatoid arthritis. Comorbidities are linked to poorer outcomes for patients with rheumatoid arthritis, including worsened physical disability and increased mortality.
A randomized clinical trial compared maternal blood loss with immediate and delayed umbilical cord clamping, finding no significant difference. The study included 113 women who had a scheduled cesarean delivery at term, with results suggesting that delaying cord clamping may not impact maternal bleeding.
Researchers found that adjusting CGM alarm settings can inform patients about high or low blood sugar events early, enabling timely treatments. The study suggests simpler adjustments to these thresholds could lead to better management of hypo- and hyperglycemia for people with type 1 diabetes.
A new study found that light-to-moderate exercise improves blood vessel density and muscle function in patients with sickle cell disease. After an 8-week regimen, participants showed significant improvements in their physical abilities and quality of life.
A new wetsuit material with ultra-high molecular weight polyethylene fibers can help reduce injuries from White Shark bites. The study found that the new fabrics were more resistant to puncture, laceration, and bites than standard neoprene.
Critically ill patients undergoing heart stent procedures with Impella ventricular assist devices are at increased risk of bleeding, kidney problems, stroke, and death compared to those using balloon pumps. The study suggests a need for more research on the use of these devices in clinical practice.
Tiny robots equipped with magnets are steered through arteries to break up blood clots using controlled rotating magnetic fields. This non-invasive method has the potential to improve patient comfort and reduce the risk of infection, making it a promising alternative to current treatments.
Researchers at University of Queensland have discovered markers in blood that differentiate benign moles from melanoma, as well as detect cancer spread to other areas. The blood test may monitor very early signs of the disease, allowing for better screening of patients with eye naevi.
A new study published in Blood Advances found that patients receiving multidisciplinary, holistic evaluation before undergoing transplantation have improved outcomes and survival rates. The team-based approach coordinated recommendations from various care providers and created individualized treatment plans.
Biomedical researchers at Cincinnati Children's Hospital Medical Center have developed a new rapid blood assay called PERSEVERE to detect and stratify sepsis. The test accurately predicts patient risk of death from sepsis, enabling early medical interventions with greater precision.
A study of 1,369 children found that high levels of good cholesterol and bad fats at birth can predict social and emotional development issues at age 5. Children with high-density lipoprotein (HDL) and low triglycerides showed improved psychological ratings from teachers.
A three-year clinical study found that reducing uric acid levels with the generic drug allopurinol did not slow diabetic kidney disease progression in type 1 diabetes patients. The study's conclusions provided a clear answer to an important scientific question, while suggesting further research may be needed.
Dr. Yamamoto received the prestigious Karl Landsteiner Memorial Award and Lectureship for his work on blood group genes. He has contributed to a better understanding of glycosylation polymorphisms and cancer-specific glycosylation alterations.