Articles tagged with Blood
A Vanderbilt University Medical Center study found that post-surgical bleeding is associated with a higher mortality rate compared to blood clots. The researchers analyzed nearly 15 years of data on millions of patients and found that bleeding had a consistent signal for mortality, while blood clots did not.
Scientists at Joslin Diabetes Center discovered that increased blood sugar levels can impair aerobic fitness and muscle adaptation in mice and humans. Despite this, regular aerobic exercise is still recommended for maintaining health, especially when combined with dietary changes.
Scientists identify ten regions of the genome linked to long lifespan, healthspan, and longevity, finding a potential link between iron metabolism and healthy aging. The study's findings suggest that maintaining healthy levels of iron in the blood could be key to slowing aging and living longer.
Researchers found severely limited exercise capacity in adults with type 2 diabetes, increasing risk of heart failure. Subtle impairments in blood flow and heart function were detected using advanced imaging techniques.
Researchers developed a new use for a common blood test to adjust T3 dosage, suggesting improved cardiac function and reversal of heart failure genes. The study suggests that brain natriuretic peptide (BNP) levels can be used to titrate T3 required, providing a potentially life-saving treatment for heart failure.
Researchers found COVID-19 patients with symptoms of inadequate blood supply to the lower extremities had larger clots and higher rates of amputation and death. In contrast, those with only leg symptoms were more likely to avoid amputation or death.
A review of available evidence suggests that prediabetes is associated with a higher risk of all-cause mortality and cardiovascular disease in both the general population and patients with a history of heart disease. Screening and proper management of prediabetes may contribute to primary and secondary prevention of CVD.
A new finger-stick test can estimate radiation exposure in mice with high accuracy, using microRNA biomarkers. The test distinguishes between various doses of radiation, including those requiring triage, and could improve acute radiation syndrome diagnosis and treatment.
Researchers found that infusing umbilical cord blood safely and effectively treated 44 children born with various non-cancerous genetic disorders. The treatment resulted in a halting of neurological decline and normal enzyme levels in patients with metabolic disorders, with high safety and efficacy rates.
Researchers found that mice with healthy gut microbiomes were less sick and less likely to spread infection. Introducing certain bacteria or chemical compounds improved immune responses and reduced virus levels.
A new study published in Psychoneuroendocrinology documents a clear link between stress hormone cortisol and higher blood sugar levels in people with type 2 diabetes. The research suggests that sustained cortisol levels make it difficult to control blood sugar and manage the disease.
A study found that exercising mice secretes a liver protein called Gpld1 into the blood, which correlates closely with improved cognitive function. Researchers believe this protein could be used to develop drugs that mimic the brain benefits of exercise, offering new hope for individuals unable to exercise due to physical limitations.
A study by McGill researchers found that sodium concentrations can influence circadian rhythms in mice, activating neurons associated with the master clock. This discovery opens new possibilities for treating negative health effects of long distance travel or shift work.
A study from the NIH found that neurofilament light chain (NfL) is a superior blood biomarker for diagnosing and predicting traumatic brain injury. NfL was shown to distinguish patients with TBI from controls even months to years after injury, providing a potential diagnostic option.
A study from the NIH confirms that neurofilament light chain in blood can detect brain injury and predict recovery across all stages of traumatic brain injury. The biomarker also showed strong diagnostic ability for sports-related concussions.
A new study found that a simple blood test can accurately predict concussion severity and duration, similar to expensive and invasive spinal taps. The test measures neurofilament light chain levels in the blood, which correlate strongly with the severity of concussions.
A new NIH study found that infants exposed to iodine in the neonatal intensive care unit (NICU) are at higher risk for developing congenital hypothyroidism. Infants with this condition often require thyroid hormone therapy within four weeks of birth, and permanent intellectual disability may result if treatment is delayed.
Children living in homes with private wells were more likely to have elevated blood lead levels than those with city water. Researchers found that African American neighborhoods lacking access to municipal water service faced compounded risks.
Repeated blood tests measuring liver damage biomarker FIB-4 identify people at high risk of severe liver disease. The study found that increased FIB-4 scores between testing occasions can predict future liver cirrhosis, with almost half of affected individuals identifiable.
A study by University of Colorado Boulder researchers found that TMAO, a compound produced in the gut from red meat metabolism, impairs artery function and hastens aging. Adults with higher blood levels of TMAO had significantly worse artery function and greater signs of oxidative stress.
A new polymeric heart valve, PoliValve, has been developed by scientists at the universities of Bristol and Cambridge, promising to address the limitations of current artificial valves. The device combines excellent durability with biocompatibility, making it a potential alternative for valve replacement surgery.
Researchers have developed eye drops that target caspase-9 enzyme to treat retinal vein occlusion, a common cause of blindness. The treatment has shown promise in improving retinal function and reducing swelling in a mouse model of the condition.
A study published in Circulation Research found that exposure to nitrogen dioxide from gas cookers can lower blood pressure by 5 mm Hg. Blood levels of nitrite also increased after exposure, suggesting a possible mechanism linking air pollution to cardiovascular health. The findings suggest that cooking with gas may have a beneficial e...
A novel, portable device called iCoagLab has been developed to measure blood clotting ability in minutes, reducing time and accuracy of traditional tests. The test was compared to a conventional test on 270 patients and found to be as sensitive at detecting bleeding risk with higher accuracy.
A new drug lead has been developed to treat type 2 diabetes, improving blood sugar levels without nausea and weight loss. The research combines two molecules using a novel technique called 'corrination', reducing vomiting compared to existing GLP-1R agonists.
The study provides a comprehensive understanding of the diversity of blood thinners in leech saliva, shedding light on their potential use in hospital settings. The leech genome sequence offers critical insight into the evolution of bloodfeeding in leeches and may revolutionize the treatment of certain medical conditions.
Scientists at the University of Sussex have identified a potential pattern within blood that signals the presence of motor neuron disease. The discovery could significantly improve diagnosis with a future development of a blood test that identifies the unique biomarker, simplifying and speeding up diagnosis.
A new study found that older adults with low vitamin K levels had a higher risk of death over 13 years compared to those with adequate vitamin K levels. The research suggests that vitamin K may have protective health benefits as we age, particularly in reducing the risk of death.
Researchers have developed a blood test that can accurately diagnose frontotemporal lobar degeneration (FTLD) and predict disease severity. The test measures neurofilament light chain levels in the blood, which are associated with FTLD progression, clinical phenotype, and prognosis.
A new study of regular cannabis users found that high-potency marijuana concentrates spike blood levels of THC more than twice as much as conventional weed, but do not lead to greater impairment. Despite this, the study raises concerns about the potential long-term health risks of concentrated cannabis use.
A recent study published in the Journal of the American Society of Nephrology found that kidney function deteriorates with age, even in healthy individuals. The research, involving over 3,000 participants from Norway, Germany, and Iceland, suggests that kidney decline is a natural part of aging.
A study found that more than half of COVID-19 ICU patients developed clinically significant blood clots undetected by routine screenings. Researchers recommend using thromboelastography (TEG) tests to identify these patients and administer additional blood thinners.
A new study reveals that metabolic differences in Humboldt penguins' blood can indicate their nesting habitat, with distinct patterns of sugars found in sheltered and exposed nests. The findings suggest that penguins in exposed areas are more likely to be exposed to air pollution.
A study published in Radiology found that 51% of patients with a pulmonary embolism were diagnosed in the Emergency Department, and 72% of PE diagnoses occurred in patients not requiring ICU-level care. Early detection using CT angiography was key to treatment, and preventive blood thinners should be considered for COVID-19 patients.
Researchers are developing a novel approach to protein analysis using iron-detecting nanosensors. The technology detects defective iron-carrying proteins in blood, which could help explain anemia and lead to new therapeutics. This project has the potential to provide a baseline for protein analysis in the future.
High-resolution imaging of human placenta reveals uniform oxygenation levels and efficient blood flow, while also discovering rapid draining from veins and utero-placental pump contractions that facilitate better circulation and fetal growth. These findings improve placental models and optimize MRI protocols for better diagnosis.
A blood test using neurofilament light chain may predict recovery time after concussion, especially for those with multiple concussions. High levels of the biomarker are associated with severe symptoms like post-traumatic stress disorder and depression years later.
Researchers discovered that copper ions are primarily bound to ceruloplasmin and serum albumin in the blood, with implications for diagnosing and treating Alzheimer's disease. The study's findings provide new insights into normal copper metabolism and its disturbances in genetic diseases.
A new study published in Experimental Physiology found that fire service instructors experience higher levels of inflammation, which may lead to chronic health problems. The researchers suggest limiting their exposure to nine times per month to reduce the risk of cardiovascular disease.
A new blood test can identify women at risk of developing type 2 diabetes up to 10 years after delivery, allowing for potential interventions such as diet and exercise. The test uses metabolic markers that are present in the blood of women who have had gestational diabetes.
A recent study presents an automatic method to detect and segment the intrauterine cavity using artificial intelligence and deep learning techniques on MRI data from 71 pregnancies. The proposed method achieves high segmentation performance, highlighting its potential for use in daily clinical practice as a surgical planning method.
Researchers have discovered a link between exposure to certain environmental chemicals and an increased risk of chronic kidney disease. The study analyzed data from 46,748 US adults and found that elevated levels of seven chemicals were associated with markers of kidney disease.
Researchers are studying COVID-19's effects on the brain, including stroke, anosmia, and seizures. They hope to find better treatments for patients at risk of developing cognitive problems.
A new analysis found that fewer people with COVID-19 suffer from stroke compared to previous reports. However, strokes in patients with the virus tend to be more severe and have poorer outcomes.
A blood test detecting neurofilament light chain can predict which people with multiple sclerosis will experience worsening symptoms and disability over the next year. The study found that individuals with high levels of this biomarker were more likely to develop significant disability and secondary progressive MS.
A new study found that treatment with antibodies and steroids restored heart function in most children with COVID-19-related multi-system inflammatory syndrome. The majority of patients recovered quickly with intravenous immune globulin and adjunctive steroid therapy, suggesting a promising approach to managing this condition.
Researchers found critically ill COVID-19 patients with severe blood clotting who were at high risk of developing complications like renal failure, venous blood clots, and stroke. The study linked blood clotting measurements with patient outcomes, suggesting early testing may help identify and treat dangerous complications.
A clinical trial found that anti-clotting drugs alone are as effective as graduated compression stockings in preventing blood clots. The study suggests that current guidelines should be revised for patients undergoing elective surgery who are at moderate or high risk of VTE.
Research at NYU Langone Health found a link between elevated blood levels of toxic chemicals and an increased risk for celiac disease in young people. Young females were eight times more likely to become gluten intolerant, while males were twice as likely with fire-retardant exposure.
A new study found that a 'soft opt-out' system for organ donation increased consent rates by 2.1 times compared to England, with the impact taking several years to be fully realized. The Welsh system allowed organs to be donated without explicit consent from patients or their families.
A new analysis of outpatient COVID-19 clinic data provides clues to distinguish between patients with COVID-19 and those with other conditions mimicking its symptoms. Key findings include fever not being a reliable indicator, COVID-19 often presenting with various permutations of cough without fever, and loss of the sense of smell as a...
A study published in Brain found that a lag in blood drainage from the deep region of the brain is associated with ventriculomegaly and can be detected with MRI. The researchers identified this biomarker as a potential predictor for dementia and ventriculomegaly, which can be reversed by removing excess fluid.
A new genetic risk score identified more men at increased risk for abdominal aortic aneurysm and could benefit from screening to detect it prior to rupture. The study suggests that current screening recommendations should be extended to include testing for those with high polygenic risk scores.
A study published by King's College London found that spaceflight and combined oral contraceptive pill use do not increase the risk of venous thromboembolism in female astronauts. The research looked at 38 flights between 2000 and 2014 and proposed more frequent blood tests during astronaut selection and training.
A study by RCSI University of Medicine and Health Sciences found that Irish patients with severe COVID-19 infection experience abnormal blood clotting, leading to micro-clots in the lungs. This abnormal blood-clotting disorder contributes to a worse prognosis and increased risk of ICU admission.
The American Thoracic Society warns of the dangers of equating COVID-19 symptoms with high altitude pulmonary edema, highlighting key differences in pathophysiology and treatment. Clinicians must rely on scientific evidence to guide treatment, as oxygen therapy is ineffective for COVID-19-related lung injury.
A multicancer blood test safely detected 26 undiagnosed cancers and enabled potentially curative treatment in a study of over 9,900 women. The test was found to be complementary and additive to standard screening methods for detecting breast, colon, and lung tumors.
Researchers have developed a multipurpose nanoscale bio-probe that allows precise monitoring of iron disorders in cells, tissue, and body fluids. The test is more sensitive and specific than current blood testing methods, enabling early disease diagnosis and potential prevention of serious diseases.
A blood test developed by Thrive Earlier Detection Corp. has identified multiple cancers in over 10,000 women without a prior history of cancer. The study found that the test more than doubled the number of 'screen-detected' cancers, increasing from 25% to 52%.
Researchers at University of British Columbia discovered that soil silicates can help control bleeding after injury by triggering clotting. The presence of soil in wounds activates a blood protein called coagulation Factor XII, leading to the formation of a plug and limiting blood loss.