Researchers discovered an antibody drug that can destroy immune cells surrounding solid tumours, allowing T-cells to attack and kill cancer cells more effectively. The approach could improve treatments for various types of cancer, including CAR-T therapy.
The American Chemical Society has unveiled its annual 'Talented 12' list, recognizing young chemists tackling world-class problems. This year's class features researchers developing new materials, analyzing proteins, and creating innovative treatments for human diseases.
Researchers developed a fast-acting skin patch that efficiently delivers medication to attack melanoma cells, producing nine times the antibody level compared to traditional injections. The patch technology has widespread applications for other vaccines and could be used to deliver vaccines against infectious diseases.
Researchers analyzed gravel samples from three tsunami events and found a common change in composition approximately 40% of the way inland. This 'Tsunami Gravel Inflection Point' helps estimate ancient tsunami sizes, expanding research on disaster mitigation and coastal planning.
A study by researchers at the University of Queensland and University of Cambridge found high levels of agreement among scientists and research stakeholders on principles to prevent conflicts of interest with the food industry. However, there is ongoing debate about what constitutes acceptable interactions and funding arrangements.
New research suggests that global food waste due to overeating has a significant impact on the environment. The study estimates that excess bodyweight corresponds to roughly 140 billion tonnes of food waste globally, with growing meat consumption leading to higher land and water usage.
Researchers found that memory plays a crucial role in guiding mule deer migrations, with past migration routes and seasonal ranges having a significant influence on their choice of path. This cognitive map helps animals navigate tens to hundreds of miles between seasonal ranges.
A new study analyzed Zambia's cause of death patterns and found that eliminating HIV/AIDS in the adult age group could gain notable years of life expectancy. The study also revealed a correlation between level of education and HIV/AIDS prevalence, as well as regional variations in cause of death patterns.
A health education program that combines information with playful activities and emotional support reduced junk food intake in children, increasing physical activity among teachers. The study suggests that knowledge alone is insufficient to change behavior.
A new study aims to explore ways to share decision-making and information between humans and AI drivers, addressing concerns about perceived loss of control and fear of unknown actions. The goal is to increase user trust, consumer acceptance, and overall usability of autonomous vehicles.
A team of Australian researchers has designed a reliable strategy for testing physical abilities of humanoid robots using machine learning methods and algorithms. The findings have promising implications in the broad use of humanoid robots in fields such as healthcare, education, disaster response, and entertainment.
A new study found that people with mild cognitive impairment (MCI) who have a heart attack are less likely to receive evidence-based treatment. Despite this, researchers emphasize that MCI does not necessarily mean reduced benefit from treatment and that patients should still receive care when indicated.
A team from Ruhr-University Bochum has deciphered a new mechanism that enables the regeneration of nerve fibers in the brain and spinal cord. By eliminating the inhibiting protein PTEN, researchers can partially restore regenerative capacity in nerve cells, but direct inhibition is not suitable due to cancer risks.
A research team at Tokyo Institute of Technology successfully synthesized atomically flat oxidized borophene sheets through a simple solution-based method. The resulting material exhibits anisotropic conducting behavior, with different conductivity types depending on current flow direction.
Scientists have mapped the evolution of complex uranium oxide species, creating a detailed picture of their formation and behavior. This research has practical applications in technologies like laser spectroscopy and verifying nuclear treaty compliance.
Researchers say increasing evidence suggests age-related diseases, rather than age itself, may be the key cause of cognitive decline. This shift in thinking highlights the importance of addressing bodily changes that lead to diseases like dementia.
A new chip has been developed that can replicate the effects of osteoarthritis, allowing for the testing of pharmacological treatments. The chip uses mechanical stress to induce inflammation and degenerative processes, making it a more realistic model for disease development.
Researchers discovered a group of genes whose activity was associated with longevity in response to various interventions. The study used mice as a model organism and identified biomarkers that could facilitate the search for new longevity interventions.
Researchers discovered that the 'Australian' familial mutation in the APP TM domain leads to increased production of pathogenic amyloid-β peptides, resulting in neurodegenerative disorder. The study provides insight into a potential mechanism of Alzheimer's disease pathogenesis.
Quantum dots have been successfully modified to produce interference-free photons, paving the way for quantum communication. Researchers eliminated interferences by adding an aluminium arsenide layer grown above the quantum dots in the wetting layer.
Researchers have developed an analytical tool to design nano-antennae that can amplify electromagnetic fields of desired frequencies or polarizations. The corkscrew-shaped nano-antennae are highly sensitive to light, allowing for novel applications in information technology and sensor technology.
Researchers identified central UPS regulators as essential for degrader efficacy, and found modulator gene-networks that can inform patient stratification. The study provides new insights into the rational design of small-molecule degraders.
A new study suggests that high levels of nitrate in salt marsh sediments stimulate decomposition, releasing CO2 and reducing the marsh's ability to store carbon. This finding has implications for climate change mitigation strategies relying on blue carbon habitats like salt marshes.
Researchers have developed a new type of vaccine targeting tuberculosis, providing substantial protection against the deadly disease. The early-stage vaccine was shown to be effective in pre-clinical laboratory settings and demonstrated its ability to stimulate the immune response in the lungs.
Researchers at Tohoku University developed a new method to quantify the efficiency of crystal semiconductors, a crucial step towards creating more efficient light-emitting diodes (LEDs) and solar cells. The method uses photoluminescence spectroscopy to detect the emitted light energy, providing a unique indicator of the crystal's quality.
Research from Duke University found that children of incarcerated parents are six times more likely to develop a substance use disorder as adults and nearly twice as likely to have diagnosable anxiety. These individuals also experience significant hurdles transitioning into adulthood.
Researchers found that men and women exhibited higher pain thresholds and lower sensory pain ratings when their partners were present. The study suggests that partner empathy can buffer affective distress during pain exposure, even without verbal or physical contact.
Researchers develop a high-resolution printing method to create complex tissue shapes in a biocompatible hydrogel containing stem cells. The resulting tissue can be vascularized by adding endothelial cells, enabling the creation of functional bioprinted organs with unprecedented speed and design freedom.
Scientists at Institute of Atmospheric Physics use a new method to track pollution from cooking by applying a black carbon tracer. COA contributes 15-27% to total organic aerosol in summer and even more than 10% during heating periods, with significant enhancements of coal combustion emissions.
A new blood test developed by UCSF has shown high accuracy in detecting concussions absent on CT scans, with the potential to prevent unnecessary radiation exposure and improve patient care. The test measures brain protein levels, which are significantly elevated in patients with traumatic brain injuries.
Researchers at Caltech have discovered that strong memories are formed when multiple neurons fire in sync, providing redundancy for long-term retention. This finding has implications for understanding memory loss due to brain damage or aging.
A new study led by Penn State researchers found that people with restless legs syndrome (RLS) have a nearly tripled risk of suicide or self-harm. Despite controlling for factors such as depression and insomnia, the study suggests that RLS may be an independent variable contributing to these mental health issues.
Researchers developed an app called MedBlockChain that uses blockchain technology to prescribe optimal medicine doses for individual patients. The app also detects counterfeit products, providing a safer and more efficient way to manage pharmaceuticals.
Researchers aim to create genetically modified poplar trees that can thrive in drought-prone environments and produce feedstocks for bioenergy. The project involves using CRISPR-Cas9 gene editing tools to identify the ideal tree species for these conditions, with the goal of delivering new genotypes by the end of the project.
Researchers have discovered that microorganisms can shift from fermentation to respiration, producing more internal energy and reducing unwanted byproducts. This breakthrough enables the design of new, improved cell factories with enhanced efficiency.
A Canadian study found that individuals taking anti-depressants and/or anti-psychotics can lose weight with a weight management program, regardless of their medication use. The study analyzed data from 17,519 patients and showed significant weight loss in both men and women.
A recent study of over 400 teenagers found no significant link between smartphone usage and poor mental health outcomes. In fact, adolescents who sent more text messages reported feeling better, suggesting a potential positive impact of digital technology on their well-being.
Hospitals with lower pediatric readiness scores have significantly higher mortality rates among critically ill children, highlighting the importance of preparedness in emergency care. The study suggests that efforts to improve hospital preparedness could save lives and guide policy responses.
Researchers study how gonorrhea develops resistance to antibiotics, identifying key mutations and structural changes. Understanding these mechanisms can lead to the development of new treatments and diagnostic tests.
TTUHSC researchers engineer mutant channels to capture atomic resolution pictures of ion-bound configurations, providing evidence for the canonical model proposed by Nobel laureate Roderick Mackinnon. This discovery could lead to developing new drugs targeting K+ channels for treating life-threatening conditions.
The National Institute on Minority Health and Health Disparities has funded 11 research centers in minority institutions to foster the next generation of researchers and address health disparities. The centers will focus on diseases disproportionately affecting minority populations, including cancer, cardiometabolic diseases, and HIV/A...
Researchers have developed a novel genome-editing technology, SATI, that can target a broad range of mutations and cell types in live organisms. This breakthrough could lead to treatments for genetic disorders such as Huntington's disease and progeria by correcting faulty genes without replacing them.
Salk scientists discover that astrocytes are required for long-term memory formation and consolidation in mice. The study found that disabling astrocytes led to significant deficits in remote memory retention after a few weeks.
Japanese scientists found that observing one's own hand movements in video-assisted therapy enhances brain activity and speeds up rehabilitation for stroke patients. This technique promotes brain plasticity, allowing the brain to rewire and regain movement and senses.
A new center at UC Riverside aims to reduce health disparities among Latino communities and marginalized populations in inland Southern California. The center will use a community-based approach to assess and improve the health of underserved populations.
A global study finds that birds with smaller brains thrive in variable environments by using alternative ecological strategies, such as large bodies and high reproductive rates. In contrast, big-brained birds are less adaptable and invest more time in raising fewer offspring.
The researchers developed a 3D organ-on-chip platform using bioelectrical sensors to measure the electrophysiology of heart cells in three dimensions. This platform enables studying cell communication in multicellular systems, potentially screening drugs on human-like tissue.
The study models a system using light to generate an electromagnetic field, polarizing neutral nanoparticles made of insulating materials. The technique has the potential to provide thrust for tiny spacecraft without an electrical power supply.
Caregivers of people with dementia experience significant sleep loss, estimated at 2.5-3.5 hours per week, affecting both their mental and physical health. Simple interventions such as morning sunlight, regular bedtime routines, and moderate exercise can improve caregivers' sleep quality.
Researchers from the University of Calgary have discovered a molecule that can prevent white blood cells from binding to tissues in the lungs, stopping inflammation and potential organ damage. This breakthrough could lead to treatments for conditions like sepsis, acute lung injury, and cancer metastasis.
Researchers at UMass Amherst discover that consuming fried foods can exacerbate conditions of the colon, including colonic inflammation and tumor growth. The study suggests that eating fried foods may make diseases like IBD more aggressive in susceptible individuals.
For the first time, researchers have visualized chemical processes in unprecedented detail using molecular electron microscopy. This breakthrough allows for the observation of discrete stages in chemical reactions, which could aid in the development of methods to synthesize chemicals with greater control and precision.
A recent study published in Mayo Clinic Proceedings found that dog owners had lower cardiovascular disease risk factors and healthier cardiovascular profiles compared to non-pet owners. The study discovered that the benefits of dog ownership on heart health were most pronounced for those who owned a dog, regardless of age, sex, or educ...
Research by Marco Del Giudice reveals parasites manipulate host behavior to increase transmission chances and alter neural functioning. Hosts evolve countermeasures to evade manipulation, but these adaptations may also create new vulnerabilities.
A new study by UCL found that nearly half of elite athletes have untreated tooth decay and a third report negative impacts on training and performance. Despite frequent brushing and flossing habits, sports drinks, energy bars, and energy gels are linked to increased risk of oral disease.
Research finds that patients from areas with cleaner air are more sensitive to changes in pollution, while those from more polluted cities can adapt to fluctuations. A higher incidence of PCI procedures was observed in winter and rose along with increasing pollution.
A team of scientists from FEFU developed a software module to automatically diagnose defects in sensors and electric drives in various kinds of robots. The system can compensate for detected defects in real time, preserving the required levels of operating quality.
Researchers found that a dramatic increase in North Atlantic salinity caused the Arctic-Atlantic gateway to close, preventing ocean-sinking and kickstarting the modern circulation. The study suggests that changes in the Atlantic conveyor belt could dramatically alter Europe's climate in a future warm world.
Researchers found that high-intensity stepping with variable tasks improved dynamic balance and balance confidence in stroke survivors. High-intensity training resulted in significant clinical gains for 57% to 80% of participants, compared to 9% to 31% following low-intensity exercises.
The study found that ancient geological events, such as mountain range uplift and river formation, drove the emergence of new species of harvestmen in the southern portion of the Atlantic Rainforest. This discovery challenges the assumption that climate fluctuations are the primary cause of high biodiversity in this biome.