A new study found that extreme dieting in female rats led to a decrease in metabolic factors and functions, including body weight and blood pressure, but resulted in a higher accumulation of abdominal fat. This increase in belly fat may cause long-term health risks for people who have previously crash dieted.
Research conducted by the University of Otago has found that New Zealand teenagers are less physically active and fit compared to previous generations. The study measured fitness using an exercise cycle test on 343 children aged 15, revealing a decline in fitness levels over time.
Reducing Canada's overweight and obese population by 50% could prevent up to 59,829 cancer cases by 2042. Effective interventions could lower cancer incidence by projecting the impact of population-level changes on cancer rates.
Researchers developed an engineered protein therapy based on the GDF15 molecule to treat obesity. The treatment successfully lowered body weights, insulin levels, and cholesterol in obese mice, rats, and primates.
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A new study in The FASEB Journal reveals that over-expression of the GTRAP3-18 gene is linked to obesity in humans. Inhibiting its interaction with POMC might be a strategy for treating leptin/insulin resistance in patients with obesity and type 2 diabetes.
New research reveals that maintaining a healthy weight is crucial in preventing high blood pressure, with participants who kept their weight in check being 41% less likely to develop increasing blood pressure. The study also found that focusing on weight management can help reduce the risk of heart disease and stroke.
Researchers developed new dosing models for remifentanil, a synthetic opioid commonly used during surgery, to improve accuracy in administering the drug to children and obese patients. The models take into account factors such as fat-free mass, weight, age, and sex to provide more personalized therapy.
A new study from the University of Illinois shows that high protein canola meal contains glucosinolates, which reduce diet palatability and affect growth performance. Pigs fed diets containing conventional canola meal had greater final body weight, average daily gain, and average daily feed intake than those fed high protein canola meal.
Researchers investigated Nepalese porters' load-carrying techniques and found that they do not use energy-conserving mechanisms like African women. Instead, porters move at a slow speed and take frequent breaks to conserve energy.
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A systematic review found that parents generally provide the most accurate estimates of their children's body weight in emergency departments. Length-based methods, such as the Broselow Tape, were the next most accurate, but still had limitations.
A physically active lifestyle can substantially decrease the genetic effect of the major obesity gene FTO on body weight in a multiethnic population. Researchers at McMaster University found that physical activity can blunt the effect of inherited obesity genes by up to 75 per cent.
A new study found that adult consumers of fresh pears had a lower body weight and were 35% less likely to be obese compared to non-pear consumers. Pear consumption was also associated with higher diet quality, as defined by the Healthy Eating Index.
A new study by Berkeley Lab researchers has identified genetic factors that influence motor performance and body weight in a genetically diverse group of mice. The findings show significant overlaps with genes related to neurological disorders and obesity in humans, providing a new framework for studying these connections.
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A systematic review by University of Bristol researchers found that consuming low energy sweeteners instead of sugar leads to reduced calorie intake and body weight. The study also suggests that LES beverages may be more effective than water in reducing weight, as they do not increase appetite.
A new study found that children's brains respond differently to high- and low-calorie foods based on their body weight. Children with more lean body mass had a greater brain response to high-calorie foods, while those with higher body fat had reduced activity in the brain when looking at healthier options.
A new Northwestern Medicine study found that walking at an easy pace for three hours a week improves prostate cancer survivors' fatigue, depression, and body weight issues. Non-vigorous walking also showed benefits in these areas, with brisk walking potentially leading to similar improvements.
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A study led by Tokyo Medical University researcher Toshihiro Nakajima found that an anti-inflammatory drug can counteract obesity in mice by regulating mitochondrial biogenesis and fatty acid breakdown. The drug, LS-102, inhibits the Synoviolin gene, leading to increased energy control pathways.
Research found that most participants underestimated weight and incorrectly identified body shapes, even among healthcare professionals. The study's findings have important implications for weight management support and advice, as many individuals may not be receiving the help they need due to inaccurate assessments.
A model describes how a person's size determines their carrying capacity, not just body weight. The study reveals that smaller individuals can comfortably carry more pack weight than expected.
Researchers from University of Eastern Finland propose a new method for measuring cardiorespiratory fitness by scaling maximal oxygen uptake and maximal workload by lean mass. This approach can avoid confounding effects of body adiposity, leading to more accurate assessments of an individual's functional capacity.
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Researchers identified a gene that plays a fundamental role in regulating body weight and nutritional status. The study found that loss of the gene's function leads to morbid obesity in both humans and mice, providing new insights into pathways controlling body weight and insulin sensitivity.
A recent study by Bowling Green State University researchers found that applicants with a high body mass index (BMI) were less likely to be offered admission after an in-person interview. The study, published in the journal Obesity, followed 97 applicants and suggested that weight bias may be stronger for female applicants.
A new study in mice found that fathers' diets before conception impact their offspring's body weight and fat content. Male offspring of paternal mice with diet-induced obesity had higher body weight and increased body fat compared to control mice.
Scientists identified how a chicken's genetic make-up affects its signals of fullness, shedding light on why some breeds overeat and affecting reproduction. The study could help develop diets reducing excess growth naturally in birds.
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A new study published in the International Journal of Obesity found that genetics account for 30% of individual differences in childhood body weight. The research used Genome-wide Complex Trait Analysis to identify genetic variants associated with childhood obesity, providing insights into the 'missing heritability' problem.
A team of scientists discovered that the ancient piranha relative Megapiranha paranensis had a bite force that could crush bone and pierce through thick shells, rivaling even the mighty T. rex. The study, published in Scientific Reports, used computer simulations to estimate the bite forces of living and extinct piranhas.
A new life sciences study using 14 years of data on gray wolves in Yellowstone National Park found that cooperative group behavior and a mother's weight are crucial for raising successful offspring. Larger packs tend to get larger and win the 'arms race' of holding territories against competing packs.
Researchers found that mother wolves' body weight and pack size play a crucial role in enabling pups to survive and thrive. The study suggests that managers can use information on pack size, female wolf weight, and disease prevalence to set harvest limits and ensure sufficient population growth.
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A survey of carers and pharmacists found that they often incorrectly calculated paracetamol doses for overweight children. The recommended dose should be adjusted according to the child's actual body weight, but many responders got it wrong. To prevent adverse consequences, simple evidence-based dosing guidelines must be developed.
A team at the University of Vermont discovered that crowdsourcing can effectively predict user behavior, such as body weight and electricity use. The experiment showed that self-directed questions and answers by visitors to websites led to computer models that accurately predicted these outcomes.
Researchers from Max Planck Institute decoded genes for extreme body size in mice, revealing 67 loci and new genes regulating energy balance, metabolic processes, and growth. The study's findings suggest that artificial selection can parallel natural selection to alter similar genes, shedding light on the genetic basis of complex traits.
Researchers at the University of Cincinnati found evidence that BPA can alter the structure of the uterus, leading to increased susceptibility to pyometra, a potentially deadly infection. In animal models, exposure to BPA induced immune cell numbers in the uteri, which were five-fold higher than control animals.
Research found that over half of school children carry rucksacks weighing 10% or more of their body weight, increasing the risk of back problems. Girls are more susceptible to back issues, which worsen with age. Experts advise parents and teachers to promote healthy backpacking habits.
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A new clinical trial shows that high doses of 'load' through programmed electrical stimulation of the muscle significantly slows bone density loss in patients with spinal cord injury. Average bone density in the femur was almost 40% lower in patients who received low or no load compared to those who received high load.
Research has found that obesity is associated with neuronal injury in the hypothalamus, a crucial brain region for regulating body weight. Additionally, turnover of nerve cells in this area is inhibited by obesity, indicating a significant impact on energy balance control.
A recent study published in JAMA found that adhering to a healthy lifestyle, including not smoking, exercising regularly, and eating a balanced diet, can significantly lower the risk of sudden cardiac death in women. The study analyzed data from over 81,000 women and found that those who met four key lifestyle criteria had a 92% lower ...
A recent study found that coffee made from capsules contains higher levels of furan, a toxic compound linked to cancer, compared to drip coffee. The levels were highest in espresso and lowest in instant coffee. However, the amounts are still within safe limits for human consumption.
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A study found that media exposure to idealized body shapes improves women's body satisfaction, at least initially. However, this effect is often accompanied by increased dieting behavior and ultimately unsustainable body image.
A new mouse model has been created to study how lipid sensing and metabolism in the brain relate to energy balance and body weight. The research found that mice with a deficiency of lipoprotein lipase in neurons became obese on a standard diet, leading to decreased food intake and increased sedentary behavior.
A two-year study found that children who approach food with emotional over-eating or boredom tend to be overweight, while those who avoid food due to fussiness or slow eating are more likely to be underweight. The researchers suggest that household environments and parental behaviors play a significant role in shaping these early food ...
Researchers have developed an improved tool for translating lizard body lengths to weights, enabling the evaluation of species health and ecosystem condition. The method, based on empirical evidence, can predict weights of lizards in a reliable and standardized manner.
A double-blind, randomized placebo-controlled trial found that high doses of ursodeoxycholic acid failed to improve overall liver histology in patients with nonalcoholic steatohepatitis. Only lobular inflammation showed significant improvement in certain subgroups.
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A new study reveals that reduced energy expenditure is the primary cause of rising body mass index (BMI) levels in children in Great Britain. Despite a marginal increase in total sugar intake, mean body weight and BMI increased significantly over the period.
Researchers found that moderate physical loading, such as carrying one's own body weight, may actually delay disc degeneration and reduce severe back symptoms. The study contradicts the long-held assumption that routine lifting is bad for your back.
Scientists found that barefoot runners avoid heel-striking by landing on the middle or front of their foot, reducing impact collisions. This approach requires different muscle engagement, which must be transitioned to for those accustomed to wearing shoes.
The Lancet article advocates for tailoring antibiotic dosing to individual patients' physical characteristics, particularly for those with large body sizes. This approach could improve treatment effectiveness and safety, especially considering the increasing prevalence of obesity-related infections.
Researchers found no association between light-to-moderate alcohol consumption and reduced risk of functional decline over time. Lifestyle-related characteristics such as physical activity, body weight, education, and income were identified as the real determinants of the reported beneficial effects of alcohol.
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A new study reveals that communication problems and misunderstandings are the primary causes of physical strain in dementia care. Effective communication techniques, such as explaining instructions with different words and using body language, can help reduce this strain.
A high-density of fast food outlets was associated with a 3-pound weight increase and 0.8-inch waist circumference rise among frequent eaters. In contrast, high-walkability neighborhoods were linked to a 2.7-pound weight loss and 0.6-inch waist size decrease.
A new study by Scientific Food Solutions demonstrates that Comfort C provides 275 percent faster absorption in the first 60 minutes compared to other brands. This results in higher body weight-adjusted vitamin C concentration changes from baseline at 60 minutes.
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A recent study found that even light loads of 26 pounds can decrease upper extremity blood flow, contributing to shoulder fatigue. Backpack straps typically compress the axillary vein, causing abnormally high blood pressure and subsequent decreased blood flow in the shoulders and arms.
Researchers found a link between obesity and left ventricular hypertrophy (LVH), a thickening of the heart muscle, in obese patients with a BMI of 30 or greater. The study analyzed 17,261 heart ultrasounds and identified narrowing of the aortic valve as a strong predictor of LVH.
Young female drivers are showing an alarming increase in fatal automobile crashes related to alcohol use and a failure to use seatbelts. Airbag studies suggest that these occupants, especially those under 4'11
Research reveals improved treatment outcomes for individuals with anorexia nervosa, including increased fertility and reduced long-term mortality. The study highlights the importance of biologically driven avoidance behavior in the development of the disorder.
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Researchers at the University of Toronto found that male Australian redback spiders develop faster in areas with high female populations, allowing them to find mates before other males. This adaptation enables them to optimize their reproductive success despite intense competition for limited mating opportunities.
A study found that adults and teens who eat beans have lower body weights, smaller waist sizes, and higher fiber intake than those who don't eat beans. Adult bean eaters also consume less total and saturated fat, reducing their risk of obesity by 22%.
A survey of 2,461 diabetes patients found that many had a less-than-accurate view of healthy body weight. Women were more likely to correctly identify a normal BMI range as healthy, while men and obese individuals often overestimated their ideal weights.
Researchers identified an abnormal variant of β-MSH in five out of 538 obese children, which was more common in overweight or obese family members than in normal-weight relatives. The mutation altered the hormone's structure and ability to stimulate brain receptors, leading to increased obesity risk.
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Researchers discovered divergent neuronal pathways at the melanocortin-4 receptor (MC4R), controlling food intake and energy expenditure. The study provides new insights into the intricate process of maintaining stable body weight, with potential implications for obesity treatment.
A study published in Nature Neuroscience reveals that AgRP neurons play a crucial role in regulating eating behavior and body weight. The research found that these neurons are essential for acute regulation of eating, and their destruction leads to anorexia and changes in blood glucose levels.