Having obesity before and during early pregnancy is linked to adverse outcomes like high blood pressure, preeclampsia, and gestational diabetes. These complications account for a small percentage of increased cardiovascular disease risks in the years following pregnancy for people with obesity.
Researchers found tirzepatide equally effective in treating young-onset and late-onset type 2 diabetes, improving HbA1c levels and weight. The drug also showed similar benefits in cardiometabolic markers such as waist circumference and blood pressure.
In a randomized clinical trial, weekly tirzepatide showed greater reductions in HbA1c levels and body weight compared to prandial insulin as an additional treatment in people with inadequately controlled type 2 diabetes. The study also found less hypoglycemia with tirzepatide.
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Women who maintained a stable weight were 1.2 to 2 times more likely to achieve exceptional longevity compared to those who lost 5% or more, with a 51% lower survival rate at age 90. Stable weight is associated with increased longevity in older women.
Researchers at the Laureate Institute for Brain Research found significant effects of floatation-therapy on body image and anxiety in patients with anorexia nervosa. The study showed immediate and sustained reductions in body image dissatisfaction and improved anxiety, which remained after treatment and lasted up to six months.
A randomized controlled study found that participants who restricted their daily eating to between noon and 8 p.m. lost more weight and showed similar improvements in blood sugar levels compared to those on a calorie-restricted diet.
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A large-scale study of 107 countries and regions found a strong association between daily soft drink consumption and the prevalence of overweight and obesity among adolescents. The findings suggest that reducing soft drink consumption is crucial in combating adolescent obesity.
A study finds that additional recommended cervical cancer screenings before birth are associated with an increased risk of preterm delivery. The findings suggest that cervical cancer screening guidelines should consider the downstream implications for preterm delivery risk when weighing population-level costs against benefits.
Researchers discovered that using fat-free mass for gentamicin dosage calculation yields more effective results than traditional methods. This method is particularly beneficial for premature babies, who have weaker kidneys and require adjusted dosing.
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A recent international study of over 745,000 adolescents from 41 countries found a decrease in those who overestimate their weight and an increase in those who underestimate it. This shift could reduce the effectiveness of public health interventions aimed at weight reduction in young people, as they may make unhealthy lifestyle choices.
Research from University of Illinois Chicago found water fasts spur noticeable short-term weight loss, but metabolic benefits disappear soon after fast ends. Participants lost 4-10% of their weight during the fast, and some gained back the lost weight within three months.
NUTRITION 2023 brings together leading nutrition experts to present groundbreaking research and discuss the latest developments in nutrition science. The event will feature scientific symposia, educational sessions, and award lectures covering topics such as food systems, human health, and nutritional interventions.
A new study found that a higher body mass index (BMI) increases the risk of five different rheumatic diseases, including gout and psoriatic arthritis. Women are more susceptible to these diseases than men, particularly those who have gone through menopause.
Once-weekly Icodec demonstrated superior HbA1c reduction compared to once-daily Degludec after 26 weeks, but no difference was found in weight change. However, Icodec showed a higher rate of combined level two or three hypoglycemic events
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Research reveals that women with PCOS experience significant body image concerns, including greater self-classification as overweight and lower body satisfaction scores. This correlation may increase the risk of developing eating disorders like anorexia or bulimia.
A new family-based treatment approach for childhood obesity has been successfully implemented in pediatric primary care settings, leading to improved weight outcomes over 24 months. The treatment's effectiveness was found to extend beyond the treated child, with siblings also experiencing improvements in weight.
A recent study of 106,000 births in New York City found that neighborhoods with healthier food options had lower rates of small for gestational age births. Higher densities of unhealthy food retail establishments were linked to increased risks of large or small-for-age birth weights.
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A study of treatment-naïve transgender youth found that nearly two-thirds reported eating an unhealthy diet, over three-quarters did not engage in physical activity, and half did not get enough sleep. The research highlights the need for individualized medical and nutrition interventions to protect their long-term metabolic and cardiov...
A new pilot study found that even low levels of saccharin, acesulfame-K and cyclamate can modulate the copy rate of genes in white blood cells, sensitizing them to certain immune stimuli. The researchers also discovered that taste receptors may act as sensors for the cellular immune system.
A study of 307,000 neonates with very low birth weight found that increased use of probiotics in hospitals was associated with reduced risk of necrotizing enterocolitis, but not sepsis or mortality rates. The adoption of routine probiotic use increased slowly from 2012 to 2019.
A comprehensive review of 169 clinical trials found that the effect of fructose-containing sugars on adiposity varies among food sources and energy control. High doses of certain sources, like SSBs, lead to increased body weight, while others, such as fruit and honey, show moderate beneficial effects when consumed in moderation.
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Despite the decline in most services, FQHCs reported an increase in patient visits for substance use disorder, depression, anxiety, and sexually transmitted infections. Quality-of-care measures also plummeted, with only one measure returning to pre-pandemic levels.
A new UCLA study identifies sex-specific brain signatures associated with obesity in men and women, revealing differences in brain networks related to early life adversity, mental health, and sensory stimulation. The findings suggest the need for tailored interventions based on an individual's sex.
A recent study has identified 60 unique brain proteins that may influence body weight via their expression in the brain. Genetic factors are believed to contribute to up to 50-75% of BMI variation, with the brain playing a critical role in regulating energy homeostasis.
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A new study explores the growing trend of patient influencers promoting prescription drugs on social media, often with close ties to pharmaceutical companies. Despite some good intentions, researchers raise concerns about the lack of medical training and potential for misinformation, highlighting the need for greater regulation.
New research reveals that excess weight or obesity is more deadly than previously thought, with about 1 in 6 US deaths related to it. The study challenges the 'obesity paradox' and highlights the pitfalls of using body mass index (BMI) as a health metric.
Participants who reduced their social media use by 50% saw significant improvements in how they felt about their weight and overall appearance. The study suggests that limiting social media use may be a feasible method of producing short-term positive effects on body image among vulnerable populations.
Researchers found that young adults post-ACLR who exhibited lower patellofemoral joint (PFJ) loading during hopping were more likely to develop PFJ osteoarthritis at 1-year and worsening PFJ osteoarthritis between 1-5 years. Lower PFJ contact force was linked to increased risk of early osteoarthritis.
A new study found that long-term voluntary wheel running improved skeletal muscle and bone parameters in female mice, but the effects varied depending on body weight. High body weight was more beneficial for muscle and bone health with aging, especially when combined with exercise.
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Women who followed most aspects of a healthy lifestyle had about half the risk of long COVID compared to those without any healthy lifestyle factors. Maintaining a healthy body weight and adequate sleep were strongly associated with lower risk of long COVID.
Researchers analyzed data from the VITAL trial and found that vitamin D supplementation increased biomarkers associated with vitamin D metabolism in people, regardless of their weight. However, these increases were significantly smaller in people with elevated BMIs, suggesting a blunted response to supplementation.
A large cohort study found that long-term low-dose hydroxychloroquine use is associated with a low risk of developing retinopathy, while higher doses increase the risk. Regular screening can identify the issue at an early stage.
Osaka Metropolitan University scientists discovered that visual food cues influence eating behavior even when participants are unaware of them. Neural activity in the brain's frontal lobe differs depending on whether images are presented consciously or unconsciously, suggesting a role for unconscious processes in controlling eating beh...
A study suggests that increasing the inefficiency of physical activity, like walking in the style of Monty Python's Mr. Teabag, can have important public health benefits. Adults could achieve global physical activity targets by doing just a few minutes of teabag-style walking per day.
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A study of over 1000 Australian adults found that people with trouble sleeping were more likely to have indicators of poor cardiometabolic health, including inflammatory markers, cholesterol, and body weight. Prioritizing a good night's sleep is crucial for maintaining good health, according to researcher Dr Lisa Matricciani.
A new study from the UConn Rudd Center for Food Policy & Health found that certain weight-related words lead to emotional distress in adolescents. Preferred terms included 'healthy weight' and 'normal weight', while words like 'obese,' 'fat,' and 'extremely obese' elicited negative emotions.
Researchers at the University of Ottawa have discovered that patients with electrolyte abnormalities are twice as likely to be diagnosed with an eating disorder. This study analyzed Ontario health data between 2008 and 2020, identifying a potential preventative treatment for approximately 1 million Canadians.
A genetic variant associated with a 10-15% reduction in fat storage has been identified in 60% of Europeans. Researchers studied the effect of this variant in mice and found it to be linked to leanness, highlighting the complex interplay between genetics and obesity.
Researchers identified a genetic variant that predisposes people to being slim, carried by 60% of Europeans. The variant affects the amount of fat stored in the body and is associated with the biochemical signalling pathway that tells cells what nutrients are available.
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A study published in Science Advances reveals that physical exercise triggers a neuromuscular circuit that links the production of interleukin-6 to muscle fat breakdown. This circuit is crucial for weight loss and has significant implications for obesity treatment.
Researchers found that short bursts of activity after meals can improve the body's ability to use amino acids from food to build muscle proteins. Breaking up prolonged sedentary periods with brief activity 'snacks' may help maintain muscle mass and quality, according to a University of Toronto study.
A recent study published in Journal of Science and Medicine in Sport reveals that high aerobic fitness does not protect children from metabolic syndrome. In contrast, a lower risk was observed when considering body size and composition.
A new study in mice has mapped the cells, genes, and pathways that respond to exercise and diet, offering potential targets for drugs that mimic exercise's benefits. Exercise was found to push these systems in the opposite direction of high-fat diets.
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A large study of former smokers found that those adhering to evidence-based recommendations for body weight, diet, physical activity, and alcohol intake had a significantly lower risk of death. The study included nearly 160,000 older U.S. adults and showed that better lifestyle habits can reduce mortality risk from various causes.
Research in rats found that an enriched environment leads to better maternal behavior and higher-quality breastmilk. Mothers in enriching environments had more efficient parenting, resulting in larger offspring with increased body weights and improved social behavior.
A large-scale review by UCL researchers calls for better education of medical professionals on weight stigma to reduce the UK's obesity rate. Weight-inclusive approaches to education in healthcare were found to be effective in challenging stereotypes and improving attitudes among medics.
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The American Society for Nutrition (ASN) emphasizes that all methodologies in nutrition research contribute to the discipline and advance health and well-being. The ASN-commissioned white paper reviews various methodologies used in nutrition research, highlighting their strengths, limitations, and interpretations.
Researchers found that the effectiveness of exercise depends on the time of day, with morning exercise reducing belly fat and blood pressure in women, while evening exercise increasing muscular performance. For men, evening exercise lowers blood pressure, burns more fat, and improves heart disease risk.
A recent study published in the Journal of Endocrinology suggests that lowering blood glucose levels can partially restore reproductive hormone levels and ovulation in female mice with obesity. The study used dapagliflozin, a common type 2 diabetes medication, to treat the mice, resulting in improved fertility outcomes.
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A study of 50 people found that higher body weights were inversely correlated with anti-SARS-CoV-2 antibody levels six months after receiving two doses of the Pfizer/BioNTech COVID-19 vaccine. The findings suggest that weight may impact immune response to the vaccine.
A new weight-loss intervention has been developed to target the instinctive desire to eat, particularly in individuals who struggle with resisting food cues. The Regulation of Cues program trains individuals to use natural hunger cues, reinforces tolerance of cravings, and inhibits urges to eat palatable foods when not physically hungry.
A recent study analyzed data from 421 adults with type 2 diabetes and found that achieving optimal blood pressure, glucose, cholesterol, and body weight levels can significantly improve life expectancy. By targeting these key health metrics, individuals with type 2 diabetes may be able to extend their lifespan.
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A study by TUM confirms that physically fit primary school pupils perform better in terms of concentration and health-related quality of life. The results show a positive correlation between physical fitness, concentration, and overall well-being.
A study identifies new biomarkers that predict the presence of subclinical atherosclerosis, providing a non-invasive way to detect cardiovascular disease. The research team analyzed blood plasma samples and validated three proteins as biomarkers, improving the prediction of cardiovascular risk.
Scientists have generated an atlas of cell types in white adipose tissue, identifying novel subpopulations linked to increased risk of metabolic disease. The study provides a comprehensive resource for translational research into human metabolic diseases.
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A new study found significant associations between student discomfort and being weighed by physical education teachers compared to school nurses. Student dissatisfaction with their weight and perceived overweight status were linked to increased discomfort with the weight measurement process.
A study of 362 children found no association between increased body weight and the risk of thyroid cancer. The research evaluated these children who had been diagnosed with thyroid nodules.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism has found that men with high levels of body fat are more likely to have lower bone density and an increased risk of fractures. The researchers analyzed data from over 10,800 people under 60 years old and found a strong positive association b...
A study of 744 Polish adults found that less than two thirds can correctly estimate their own BMI, with men underestimating their size more frequently. The research suggests that psychological interventions may help people better manage their weight by addressing body size perceptions.
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Scientists at Nanyang Technological University have developed a novel therapeutic approach to tackle obesity, reducing body fat and improving blood markers through a hydrogel injection and near infrared light treatment. The treatment shows significant promise in lab trials, with mice experiencing reduced body mass and improved metabolism.