Researchers identified a specific type of gut bacteria, Turicibacter, that promotes metabolic health and reduces weight gain in mice. The bacterium produces fatty molecules that are absorbed by the small intestine, improving ceramide levels and preventing excessive weight gain.
A study found that reducing body fat percentage improves long-distance running and cross-country skiing performance, but converting body fat into muscle tissue is a more effective way for female athletes to optimize their body composition. Training and dietary habits that promote muscle growth outweigh the benefits of weight loss.
A recent study suggests that adverse childhood experiences may increase the risk of obesity in Latinx and Hispanic youths. The study found that promoting resiliency-focused skills may help improve pediatric weight trajectories among these populations, potentially mitigating the impact of adverse experiences on health outcomes.
A national study led by Curtin University found that Australian's location significantly affects their body weight. The research tracked individuals across 14 years and discovered that people tend to adapt to the typical weight profile of their new community., Local food environments, walkability, and access to green space are key fact...
Withdrawal of tirzepatide after 36-week treatment led to 25% or greater weight regain in most participants within a year, reversing initial cardiometabolic parameter improvements. Continued obesity treatment is crucial for sustained benefits.
A doctor warns of critical treatment gaps in eating disorders, highlighting the dangers of ignoring physical warning signs and behavioral indicators. Dr. Jennifer Gaudiani advocates for integrated medical and psychological care to address the urgent need for effective treatment.
A new medication called DR10624 has shown promising results in reducing high triglyceride levels by over 60% in patients with severe hypertriglyceridemia. The treatment also improved cholesterol and liver health, offering a potential alternative for managing this condition.
A new study found that combining GLP-1 receptor agonist medications with healthy lifestyle habits significantly reduces the risk of major adverse cardiovascular events, including heart attacks and strokes. The research suggests that adopting multiple healthy behaviors can lower cardiovascular risk even further.
Three new Cochrane reviews found GLP-1 drugs result in clinically meaningful weight loss, but evidence on longer-term outcomes and side effects is limited. The wider use of these drugs should consider social and commercial determinants to avoid deepening existing health inequities.
SourceCochrane·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateOct 29, 2025
A new study found that fitness and calorie counting apps can lead to negative emotions such as shame, disappointment, and demotivation among users. The researchers called for a more holistic approach focusing on wellbeing rather than rigid calorie counting and exercise quantification.
A new Cochrane review found that immediate skin-to-skin contact between newborns and their mothers significantly improves exclusive breastfeeding rates, optimal body temperature, breathing, and heart rate. The review suggests that skin-to-skin contact should be the global standard of care for all babies after birth.
SourceCochrane·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateOct 21, 2025
A recent study published in Integrative and Comparative Biology found that bonnethead sharks' skin undergoes significant changes as they mature, with younger sharks having fewer ridges on their denticles. These changes likely improve swimming performance and protect the skin from predators or injuries.
A repeated cross-sectional study shows that cardiometabolic risk factors in Spanish children have improved over the last 30 years, with decreases in excess weight, lipid parameters, and blood pressure. The study provides valuable insights into the evolution of cardiometabolic risk in children.
A new study by Florida Atlantic University researchers found that heat does not significantly affect the cognitive ability of sea turtle hatchlings. However, higher incubation temperatures negatively impact their physical traits, including shorter incubation durations, lower hatching success, and more frequent scute anomalies. The stud...
A new study published in JAMA Network Open shows that regular phone support after losing weight is crucial for maintaining weight loss. Participants who received monthly phone calls maintained an average of 8% weight loss from their starting weight, with about 60% keeping off at least 5% of their initial weight.
A systematic review and meta-analysis of 18 trials found GLP-1 RAs significantly improved glycemic and weight outcomes in children and adolescents with type 2 diabetes or obesity. However, gastrointestinal adverse effects warrant attention in long-term management.
Researchers at Penn State found that weight fluctuations and changes can lead to faster cognitive decline in older adults. The study analyzed data from 4,304 participants and showed that those with greater variability in weight experienced more rapid cognitive declines.
A cohort study shows bariatric surgery significantly lowers major metabolic comorbidity risk compared to medical weight management. The procedure is deemed a durable approach for obesity-related risk mitigation.
A landmark clinical trial found that Transcendental Meditation significantly reduced diabetes risk factors and supported weight loss in older Black women at high risk for heart disease. Meditation improved blood sugar control, insulin resistance, cholesterol, and weight.
A new study suggests that being overweight (BMI 25–29.9) may actually be protective in the short term after surgery for older adults, with a 0.8% 30-day all-cause mortality rate compared to 18.8% for those with normal BMI.
Researchers designed an ideal primary care visit scenario that emphasizes patient-centered communication, respect, and inclusivity. A survey of 250 adults with obesity found that most preferred this approach, citing doctors who listen attentively and treat weight issues sensitively.
A telephone-based weight loss intervention significantly reduced weight in breast cancer patients with overweight and obesity. The study suggests that this intervention may improve disease outcomes, warranting further investigation in future trials.
A new study found that adolescents with higher blood levels of per- and polyfluoroalkyl substances (PFAS) prior to bariatric surgery regained more weight and had greater increases in waist circumference up to five years after surgery. Researchers believe PFAS exposure disrupts endocrine and metabolic processes, leading to weight regain.
A new study suggests that using glucagon-like peptide-1 receptor agonists (GLP-1 RAs) before surgery can help control blood sugar and support weight loss, potentially improving surgical outcomes. The medication was not associated with increased risk in 12 studies reporting postoperative outcomes.
According to a RAND report, nearly 12% of Americans have used GLP-1 weight loss medications, with women between 50-64 years old making up about one-fifth of this group. The survey also found that half of those who have used the drugs experience nausea as a side effect, while one-third experience diarrhea.
Researchers found that high body-fat percentage was strongly linked to increased mortality risk from any cause and heart disease. In contrast, overweight/obese BMI was not associated with a higher risk of death.
A new genetic test can predict adulthood obesity in early childhood, allowing for targeted preventative strategies. The test was developed using data from over five million people and found to be twice as effective as previous tests at predicting obesity risk.
Research warns that GLP-1 drugs may not provide the long-term health benefit of improved heart and lung function. While they help with weight loss, patients may experience significant muscle loss, which can increase cardiovascular disease risk. Doctors are urging additional research to better understand the effects of these drugs.
A survey of 2,000 single U.S. adults found that GLP-1 weight-loss drugs are affecting people's sex lives and dating experiences, with men reporting increased libido and confidence. Women, on the other hand, are more likely to report low libido and decreased sexual function.
The article provides practical strategies for managing symptoms in patients receiving GLP-1 RAs, focusing on diet and physical activity interventions to support muscle and nutrient preservation. Lifestyle factors remain crucial in GLP-1 RA treatment for effective weight management.
A new study found that intermittent energy restriction significantly improved fasting blood glucose and triglycerides, while also increasing insulin sensitivity. The IER group showed the greatest advantages in reducing these markers compared to time-restricted eating and continuous energy restriction groups.
Researchers found that tirzepatide significantly reduced body weight, food intake, and measures of appetite compared to a placebo and liraglutide. Functional magnetic resonance imaging revealed reduced activity in hunger-sensitive brain areas while viewing high-fat foods.
A large study of Danish children found that COVID-19 mitigation policies affected BMI across all weight categories, not just those with obesity. The findings suggest that age and BMI class differences were present, warranting policies targeting all BMI groups in children.
Researchers have discovered how FGF19, produced in the intestine, acts on specific regions of the brain to regulate energy expenditure. The hormone stimulates thermogenic adipocyte activity, leading to increased fat burning and improved blood glucose levels in obese animals.
A study found that a grandmaternal age difference of ≤-9 years significantly increases the risk of pregnancy cardiometabolic disorders. The researchers analyzed data from 2,235 grandmother-mother pairs and discovered a nonlinear association between age differences and CMDs.
A new study found that weighted vests and resistance training did not prevent bone loss in older adults undergoing intentional weight loss. The researchers call for alternative strategies to protect skeletal health in aging populations with obesity.
A University of Oxford study found that an intensive low-energy diet programme significantly improved eating disorder symptoms in people with type 2 diabetes and excess weight at risk of developing eating disorders. The programme showed benefits persisting six months after completion.
A new study found that nearly one-third of individuals adopting healthy diets didn't lose weight but still experienced significant improvements in cardiometabolic markers, including increased HDL cholesterol and reduced visceral fat. The research suggests a healthy diet can have benefits beyond weight loss.
A Virginia Tech professor has received a proof-of-concept grant to further develop a chemical compound that could help promote weight loss by increasing mitochondrial activity. The compound, named BAM15, shows promise in preclinical studies without affecting food intake or muscle mass.
A high-fat diet leads to metabolic enzyme dysregulation, insulin resistance, and accumulation of reactive oxygen species in cells. Reversing these effects with antioxidants can mitigate damage.
This novel treatment approach yields better weight loss maintenance and cardiovascular risk outcomes compared to standard-of-care treatment. Patient-delivered lifestyle intervention combined with peer support significantly improves weight loss and reduces cardiovascular risk.
A new NIH study found that early childhood weight patterns may signal future obesity risk. The study tracked children's body mass index (BMI) from infancy through age 9 and identified two distinct growth patterns, with a smaller group following a trajectory marked by a sharp rise in BMI.
Girls who enter puberty early have a higher BMI before, during, and after puberty, increasing the risk of overweight later in life. The study found that biological differences between sexes make girls more vulnerable to this impact.
A new study from the University of Bath found that regular, moderate-intensity exercise preserves vitamin D levels in overweight and obese individuals. The study showed that exercise completely maintained the body's active form of vitamin D, which plays a key role in supporting bone health and the immune system.
The USPSTF recommends early, universal screening for syphilis infection during pregnancy to prevent congenital syphilis. Untreated syphilis can cause premature birth, low birth weight, and stillbirth in the fetus.
A recent study published in JAMA Pediatrics found that prenatal cannabis use is associated with an increased risk of preterm birth and low birth weight. The research also suggests a potential link between cannabis use during pregnancy and smaller-than-average newborns.
A cohort study found associations between pre-pregnancy overweight, smoking during pregnancy, and formula-feeding with adverse cardiovascular health trajectories in early childhood. The study suggests that addressing these factors through interventions may optimize cardiovascular health in children.
A randomized clinical trial suggests that metformin can be an effective treatment for symptomatic knee osteoarthritis in people with overweight or obesity. The study's results support the use of metformin for this condition, but further confirmation is needed in larger clinical trials.
A randomized clinical trial found that 4:3 intermittent fasting resulted in modestly greater weight loss over 12 months compared to daily caloric restriction. The study showed improved cardiometabolic outcomes, including lower blood pressure and cholesterol levels, suggesting that fasting may be a more effective approach for weight loss.
A study found that only a quarter of mental health providers correctly diagnosed bulimia nervosa, with common misdiagnoses including binge eating disorder. Excessive exercise is often overlooked as a compensatory strategy used by people with bulimia.
Most older U.S. adults support Medicare covering weight management medications, particularly those with a BMI of 30 or greater. The survey also found that more than half of participants were interested in using these medications to manage their weight.
A study found that consuming sucralose alters brain activity related to hunger and increases appetite, especially in people with obesity. The sugar substitute changes how the hypothalamus communicates with other brain regions, including those involved in motivation, potentially leading to cravings and eating behavior changes.
Researchers found significant improvements in muscle strength, flexibility, and mental health with just five minutes of daily eccentric exercise. The study suggests that even small amounts of exercise can provide sustainable benefits for sedentary individuals.
Research suggests that people with obesity experience a redistribution of their body compartments, such as increased fat trunk accumulation and lower muscle mass, particularly in extremities, as they age. This shift occurs without significant changes in BMI, making it a less useful tool for assessing weight status.
A cohort study found that healthier diets and lower waist-to-hip ratios were associated with improved brain connectivity and memory in older adults. The study suggests that interventions targeting diet and central obesity may be most effective between ages 48 and 70 to promote better cognitive health.
A responsive parenting intervention demonstrated a significant reduction in child weight outcomes from age 3 to 9 compared to a control group. The intervention's benefits were most pronounced among female participants, and its long-term effects may be sustained with a life-course approach.
Researchers found that dogs carrying the genetic variant DENND1B had higher body fat content, while humans also carry this gene linked to obesity. The study highlights the importance of fundamental brain pathways in regulating appetite and body weight.
Researchers at Durham University found that children as young as seven years old adjust their perception of body weight after seeing pictures of low or high weight bodies. The study suggests that media influences can impact both children's and adults' body perceptions, shaping their ideas about what constitutes a healthy weight.
A study of 350 patients found that taking semaglutide before bariatric surgery did not increase total weight loss and had similar health outcomes to surgery alone. Researchers suggest a surgery-first strategy may lead to better obesity treatment outcomes.
New research found that neuroestrogens produced in the brain help suppress appetite, as confirmed by experiments where aromatase expression was restored specifically in the brain. This suggests a link between neuroestrogen levels and body weight regulation.