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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

New brain-machine interface moves a paralyzed hand

Researchers at Northwestern University developed a new brain-machine interface that directly delivers electrical signals from the brain to muscles, enabling complex movement of a paralyzed hand. The device was tested on monkeys and showed promising results, with potential applications for paralyzed patients.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Knee injuries in women linked to motion, nervous system differences

A new study found that women's knees are more susceptible to injury due to differences in motion and nervous system processing. Women tend to have knee motions that make them more prone to ACL injuries, whereas men's knees process nerve impulses similar to explosive muscle usage.

New hormone for lowering blood sugar

Researchers have discovered a hormone that can be produced by fat stem cells to lower blood sugar levels and improve metabolism. The hormone appears to bypass the need for insulin, sending glucose out of the bloodstream and into muscle cells.

Study reveals how cancer drug causes diabetic-like state

A study by Dana-Farber Cancer Institute reveals that rapamycin triggers diabetic-like symptoms in some patients through activity of protein YY1. The researchers found that mice without the YY1 protein were protected against the effects, raising caution about the use of rapamycin.

Guideline: IVIg effective for certain nerve and muscle disorders

A new guideline from the American Academy of Neurology confirms IVIg as an effective treatment for Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy (CIDP). The therapy has been shown to be as effective as plasma exchange in treating GBS, with long-term use also helping to manage CIDP. Serious side effects a...

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

New 'electronic skin' patches monitor health wirelessly

Scientists have developed thin, flexible 'electronic skin' patches that can monitor brain, heart, and muscle activity without wires or invasive procedures. The patches can be applied to the skin like temporary tattoos and provide real-time health data through wireless capabilities.

Researchers unveil robot jellyfish built on nanotechnology

The University of Texas at Dallas and Virginia Tech have created an undersea vehicle inspired by the common jellyfish, which runs on renewable energy. The robotic jellyfish, dubbed Robojelly, feeds off hydrogen and oxygen gases found in water, producing only water as waste.

New discovery of proteins involved in positioning muscular nuclei

Researchers have discovered two proteins, Kif5B and MAP7, that play a vital role in positioning muscular nuclei on the edge of muscle fibers. The study, published in Nature, sheds light on the mechanism behind this process, which is essential for skeletal muscle function.

Fasudil bypasses genetic cause of spinal birth defect

Researchers discovered that Fasudil increases the size of muscle fibers and their connection to motor neurons, improving the movement of SMA mice. This treatment bypasses the genetic cause of spinal muscular atrophy (SMA) by targeting the ROCK intracellular signaling pathway.

GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Exercise changes your DNA

Researchers discovered that exercise alters DNA molecules within muscles, leading to improved strength and metabolism. The study also found that caffeine can mimic this effect, suggesting a potential alternative to traditional exercise for some individuals.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

High doses of 'load' slows loss of bone in spinal cord injury

A new clinical trial shows that high doses of 'load' through programmed electrical stimulation of the muscle significantly slows bone density loss in patients with spinal cord injury. Average bone density in the femur was almost 40% lower in patients who received low or no load compared to those who received high load.

Stretching helices help keep muscles together

Researchers at EMBL Hamburg used advanced techniques to study myomesin's three-dimensional structure and its role in maintaining muscle fibers. The discovery sheds light on the protein's function in living organisms, particularly in animal models.

When nerve meets muscle, biglycan seals the deal

A protein called biglycan is essential for stabilizing synapses at the neuromuscular junction, a process crucial for muscle control and long-term health. Research suggests that biglycan could be a potential therapy for motor neuron diseases such as spinal muscular atrophy and ALS.

Let's stretch...

Scientists at EMBL Hamburg have discovered the myomesin protein can stretch up to two-and-a-half times its length, unfolding in a previously unknown way. The study reveals the protein's superhelical architecture and unusual elastic properties, shedding new light on muscle contraction mechanisms.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Aligning the eyes: A simpler surgery for a complex condition

A new surgical procedure called superior rectus transposition with adjustable medial rectus recession has shown promising results in aligning the eyes of patients with complex strabismus. The procedure, adopted at Boston Children's Hospital, allows for precise eye movement fine-tuning in the recovery room or up to a week after surgery,...

To perform with less effort, practice beyond perfection

A University of Colorado Boulder study found that continued practice after mastering a task can decrease overall energy costs by up to 20%, making movements more efficient. The research, led by Assistant Professor Alaa Ahmed, used robotic arm exercises to measure metabolic cost and muscle activity in test subjects.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Unusual alliances enable movement

Researchers found that agrin and LRP4 form two diverse work teams to activate MuSK, enabling communication between neurons and muscles. This discovery may lead to new treatments for myasthenia gravis and other muscle diseases, as well as insights into neurodegenerative conditions like Alzheimer's and Parkinson's.

Heavy lifting for cancer research

A study by Concordia University and McGill University Health Centre found a strong link between muscle mass and strength in cancer patients with severe fatigue. The researchers suggest that specialized strength training programs could improve muscle mass and reduce fatigue, enhancing the quality of life for these patients.

Cirrhosis patients losing muscle mass have a higher death rate

Research reveals that cirrhosis patients losing muscle mass have a significantly shorter survival rate than those with normal muscle mass. The study's findings suggest that muscle mass should be considered alongside current scoring systems when assessing transplant list placement.

Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Exercise triggers stem cells in muscle

Researchers at the University of Illinois discovered that exercise can trigger adult stem cells in muscle, releasing growth factors that promote muscle regeneration. The findings may provide a link between exercise and muscle health, with potential applications for rehabilitation and preventing age-related muscle loss.

Massage is promising for muscle recovery

Researchers at McMaster University found a 10-minute massage significantly reduces inflammation in muscle, triggering biochemical signals that can aid healing. The study suggests massage may be an effective alternative to pain medications for recovery from injury.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

'Couch potato pill' might stop heat stroke too

Researchers found that AICAR, an experimental therapy, protected animals from heat-induced sudden death and may hold promise for treating people with enhanced susceptibility to heat stroke. The drug works by reducing calcium leakage from RYR1, thus diminishing heat-induced contractions and muscle damage.

Exercise in a pill may protect against extreme heat sensitivity

A compound called AICAR has been found to prevent heat-induced deaths in mice with a gene mutation that makes them sensitive to heat. The study's findings suggest that AICAR could protect young athletes and soldiers from heat-related illnesses, potentially saving lives during exercise.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Why humans choose running over walking

At around 2 meters per second, running makes better use of a key calf muscle than walking, increasing efficiency and conserving energy. This discovery sheds light on why speed walking is generally confined to the Olympics.

How work tells muscles to grow

A study in Cell Metabolism identifies serum response factor (Srf) as a crucial signal that tells surrounding muscle stem cells to multiply and join muscle fibers, controlling muscle growth. SRF's role in regulating muscle atrophy is also confirmed, with potential applications for therapies targeting its targets.

A firmer understanding of muscle fibrosis

Researchers discovered that increased production of microRNA miR-21 stimulates progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy. Inhibiting miR-21 reduced collagen levels and prevented fibrogenesis in diseased animals, suggesting it as a potential therapeutic target.

The mystery behind the building of muscle

Researchers at the Wellcome Trust Sanger Institute have identified two cell surface proteins, Jamb and Jamc, crucial for muscle cell fusion. The discovery sheds light on cellular fusion and its importance in muscle development, potentially leading to new treatments for muscle-wasting disorders.

Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Extreme cold good for exercise recovery

Whole-body cryotherapy outperforms far-infrared radiation and no treatment in enhancing post-exercise recovery for well-trained runners. Three cryotherapy sessions over 48 hours accelerated recovery more than other methods.

How muscle fatigue originates in the head

Researchers discovered that nerve impulses from muscles inhibit motor areas in the brain, leading to muscle fatigue. The insular cortex plays a key role in regulating muscle performance, with increased activity preceding fatigue.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Super athletic mice are fit because their muscles burn more sugar

Researchers at Sanford-Burnham Medical Research Institute discovered a way to reprogram muscle cells to burn sugar more efficiently, resulting in increased athletic ability and reduced lactic acid production. This novel mechanism could lead to new prevention or treatment methods for obesity, metabolic syndrome, and diabetes.

Body rebuilding: Researchers regenerate muscle in mice

A team of scientists from Worcester Polytechnic Institute and CellThera regenerated functional muscle tissue in mice using a novel protocol that combined reprogramming human cells and biopolymer microthreads. The study showed promising results, with most new muscle fibers composed of mouse cells, suggesting that fibrin microthreads alo...

Hope for muscle wasting disease

A health supplement commonly used by bodybuilders, L-tyrosine, has shown rapid and dramatic improvement in muscle wasting disease Nemaline Myopathy (NM) in laboratory tests on mice. Trials suggest it could also be effective for a range of other muscle-wasting diseases, offering new hope for treating children affected by the condition.

Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Tweaking a gene makes muscles twice as strong

Researchers have discovered a new way to build muscle by suppressing a natural inhibitor, resulting in mice and worms with super-strong muscles. This breakthrough could lead to treatments for age-related or genetics-related muscle degeneration, as well as applications for athletes and individuals with genetic muscular dystrophy.

How the fly flies

Researchers at Max Planck Institute identified the genetic switch Spalt that regulates flight muscle formation in flies. Without Spalt, flies are flightless, but can still move their legs normally. This discovery has potential medical applications for understanding and regulating human muscle function.

Frogs' amazing leaps due to springy tendons

Researchers at Brown University discovered that frogs' stretchy tendons are the key to their impressive jumping abilities. The study shows how the leg muscle shortens and loads energy into the tendon before releasing it to propel the frog forward, enabling them to jump much farther than expected.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

One molecule for muscle growth and insulin sensitivity

Two studies found that reducing NCoR in muscles increases exercise capacity and fat-burning, while reducing it in fat cells improves insulin sensitivity. The findings imply that limiting NCoR activity could be a potential treatment strategy for metabolic disorders.

Tweaking a gene makes muscles twice as strong

Researchers create super-strong mice and nematodes by reducing natural inhibitor function, leading to denser muscle fibers and increased energy delivery. This breakthrough could lead to treatments for age-related or genetically caused muscle degeneration.

Possible therapy for one form of inherited nerve dysfunction

Researchers have identified a potential oral therapy for HSAN1, an inherited nerve dysfunction characterized by progressive muscle control loss. Oral administration of L-serine reversed deoxysphingolipid accumulation and reduced neuropathy severity in mice and humans with the disease.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Targeting leg fatigue in heart failure

Researchers at the University of Leeds have discovered that leg muscle dysfunction is related to the severity of symptoms in heart failure patients. Daily activity in these patients can be limited by impaired leg muscles, not just a failing heart.

Older men with higher testosterone levels lose less muscle mass as they age

A recent study published in the Journal of Clinical Endocrinology & Metabolism found that higher levels of testosterone were associated with reduced loss of lean muscle mass in older men. Higher testosterone levels were also linked to less loss of lower body strength, particularly in those who were losing weight.

UM School of Medicine finds new pathway critical to heart arrhythmia

Researchers found a previously unknown molecular pathway controlling ion channel number and location on the cell surface, affecting heart rhythm and other muscle activity. This discovery may lead to new treatments for heart arrhythmia and related conditions such as paralysis and kidney disorders.

Face-to-face with an ancient human

A reconstruction based on the skull of Norway's best-preserved Stone Age skeleton, Viste Boy, has been scientifically rebuilt to study features of a boy who lived outside Stavanger 7,500 years ago. The model reveals a strong and muscular individual with scaphocephaly, challenging earlier theories about his health.

Improving training efficiency in horses

A study found that amino acid supplements can significantly reduce protein degradation in horse muscles after intense exercise. This could lead to an advantageous effect on muscle mass and improved training efficiency in sport horses.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.