Articles tagged with Tissue Structure
Researchers developed organoids that resemble human brain structure, investigating rare congenital brain defect Miller-Dieker syndrome. The study reveals disrupted stem cell division leading to poor organization and early differentiation of nerve cells.
Researchers at the University of Wisconsin-Madison have developed a novel technology using decellularized plant husks to create three-dimensional scaffolds for human stem cells. The scaffolds are made from cellulose and exhibit properties such as strength, rigidity, porosity, and surface area that are ideal for biomedical applications.
Scientists used OCT to observe tissue organization and behavior of living corals, identifying changes in tissue layers and fluorescent pigments under light exposure. The study reveals that corals expand their surface area at night and produce more mucus upon stress, challenging current assumptions about coral metabolic rates.
Researchers at UC San Diego have successfully printed a functional blood vessel network using 3D bioprinting, addressing a major challenge in tissue engineering. The technology enables the creation of complex microstructures with high resolution, using inexpensive and biocompatible materials.
Fin whales employ a two-tiered nesting structure to safeguard their nerves during feeding dives. The folded nerves develop 'bending stretches' that could damage them, prompting the development of this intricate mechanism.
UNSW biomedical engineers create 'smart' fabric that mimics periosteum's complex properties, with potential applications in protective suits, compression bandages, and steel-belt radial tyres. The technique involves scaling up nature's architectural patterns to produce multidimensional fabrics.
A recent study found that obesity in adolescence is associated with weakened bone structure, including increased cortical porosity and decreased trabecular density. This suggests that adolescents with high visceral fat mass and low muscle mass are at risk for permanent bone loss.
Researchers propose a wireless monitoring system for detecting concrete damage using Electromechanical Impedance sensing approach. The proposed WiAMS system utilizes a credit card-sized Raspberry Pi single-board computer, enabling remote data transfer and processing.
New research from University of Southern Denmark shows that elite athletes' muscles produce more energy-efficient mitochondria, generating up to 25% more energy. This discovery has implications for treating diseases affecting muscle function and may lead to new treatment options.
Researchers at the Wyss Institute have successfully bioprinted a functional 3D renal architecture that recapitulates key functions of the kidney, including nutrient reabsorption. The printed tissue is composed of living human epithelial cells and has been sustained for over two months in vitro.
Researchers have developed new biomaterial scaffolds that incorporate patterned architectures and regional compartments of signaling factors to control tissue development. This technology enables the formation of complex cellular structures and miniature organoid tissues, mimicking natural developmental processes.
A long-term study found that extra physical education classes improved girls' bone mass, structure, and strength. Girls who received 200 minutes of physical education per week showed significant gains in cortical thickness and volumetric bone mineral density compared to controls.
Researchers at UT Austin use thermal noise imaging to capture nanometer-scale images of collagen fibrils in skin, revealing key properties that affect elasticity. This breakthrough may lead to improved designs for artificial skin and tissues.
Kyungsuk Yum, a UTA professor, is developing nanocomposite hydrogel bioinks to overcome the barrier in 3D bioprinting. The bioinks incorporate carbon nanotubes and can change their mechanical properties during printing and after.
A new analysis by civil engineering faculty at the University of Illinois at Urbana-Champaign outlines the factors that led to the 2013 Interstate 5 bridge collapse in Washington. The study highlights the importance of updating databases to reflect minimum heights and implementing automated reporting systems to prevent similar accidents.
A new study by University of Toronto researchers found that increased Gαq/11 signaling inhibits the anabolic response to PTH and exercise in mice. This suggests that suppressing Gαq/11 signaling could be a promising target for treating bone loss.
A new study reveals that DNA, but not RNA, can contort itself into different shapes to absorb chemical damage and maintain genome stability. Researchers used advanced imaging techniques to visualize these tiny changes in DNA's double helix.
Researchers studied 7th-century A.D. temples in northwest India to reconstruct historic earthquakes, finding evidence of damage from magnitude 7.8 and 7.6 quakes. The study extended rupture zones for two major earthquakes, suggesting the region is prone to powerful earthquakes.
A team of researchers from Tufts University has successfully integrated sensors, electronics, and microfluidics into threads to create a 'smart' thread that can collect diagnostic data wirelessly in real-time. The thread-based platform shows promise for implantable diagnostic devices and smart wearable systems.
Researchers from the University of Delaware have developed a new approach to detect hidden damage in structures, using carbon nanotube composites and electrical impedance tomography. The technique can monitor the health of structures and alert owners to potential problems, with major benefits including scalability and relatively low cost.
Research on plant development, including cell division, differentiation, and organ formation, reveals new insights into the biosynthesis of auxins and the molecular control of stem cells. Key findings also shed light on the hormonal and transcriptional control of secondary cell wall formation and pollen wall development.
Researchers develop hydrogel-based platform to mimic human vocal fold tissue, enabling study of development and disease. The model will facilitate testing of new treatment options for voice disorders, a common condition affecting millions of Americans.
Researchers monitored nerve impulses in awake mice to study the flow of information between sensory perception and behavior. They discovered that different layers of the cortex handle impulses in unique ways while remaining coordinated with each other.
Scientists have bioprinted a 3-D model of placenta tissue that mimics the organ's complex structure, which could lead to better understanding and treatment options for preeclampsia. The 3D model includes trophoblasts, epidermal growth factor, and other key components, showing improved cell migration towards the growth factor.
Researchers from Kazan Federal University and Ogarev Mordovia State University conducted an in vitro study on endovenous laser ablation of varicose veins using solid-state laser radiation. The results confirmed that a heated carbonized layer on the fiber end face increases efficiency, paving the way for process optimization.
The Suomi NPP satellite captured images of the Fort McMurray wildfire, revealing its spread and impact on nearby communities. The fire forced over 88,000 people to flee, destroying 1,600 homes and buildings, and scorching over 18,500 acres.
Researchers developed clay nanotube-biopolymer composite scaffolds that improve mechanical strength, water uptake, and thermal properties. The scaffolds demonstrated enhanced biocompatibility and encouraged cell adhesion, proliferation, and neo-vascularization in vitro and in vivo.
A team of Stanford Bio-X scientists developed the first technique for viewing cells and tissues in 3 dimensions under the skin. The MOZART technique allows for real-time imaging of individual cells or molecules in a living animal, enabling doctors to monitor tumors and understand how cells break free from tumors.
A new process for making brain tissue transparent has been developed at RIKEN Center for Developmental Biology, allowing for the creation of super-resolution 3-D images of delicate structures deep in the brain. This breakthrough enables researchers to visualize synaptic changes and neural structures with unprecedented detail.
Researchers at the Wyss Institute developed a method for bioprinting thick vascularized tissue constructs composed of human stem cells and extracellular matrix. The resulting tissues can sustain and function as living architectures for upwards of six weeks, enabling controlled perfusion of fluids, nutrients, and cell growth factors.
Researchers investigated wind patterns and affecting weather systems around the shipwreck location. The study revealed strong winds of at least 31 m s-1, and a bow echo embedded in a squall line contributed to the disaster.
Researchers have developed a new method to acquire three-dimensional atlases of tissue that provide much more information, incorporating data on tissue structure and molecular profile. The new technique enables doctors or researchers to peer into the tissue and identify specific proteins within cells throughout the whole tissue.
Brown University engineers developed a new technique to understand how cells move through complex tissues, building on mean deformation theory. The algorithm analyzed images of human neutrophils moving through collagen matrices, revealing differences in contractility and rotation between healthy and sepsis models.
Tropical Cyclone Winston is intensifying near Fiji, with NASA's Suomi NPP satellite capturing images of the strengthening storm. The Joint Typhoon Warning Center forecasts Winston to make landfall on the east coast of Fiji as a major Category 4 hurricane, threatening catastrophic damage and power outages.
Regenerative medicine scientists at Wake Forest Baptist Medical Center have developed a novel 3D printing system that can produce living tissue structures with functional blood vessels. The system uses bio-degradable materials and water-based gels to promote cell growth, enabling the creation of complex tissues such as bone, muscle, an...
A recent study by the University of California, Davis, found that levees can actually increase flood risk for up to a third of residential structures and 22% of commercial structures behind them. The research team estimated long-term flood risk, probabilities of levee failure, and resulting economic losses in the Sny Island levee distr...
A team of engineers at the University of California, San Diego has successfully created a 3D-printed liver tissue model that closely mimics human liver structure and function. The new model can be used for patient-specific drug screening and disease modeling, potentially saving pharmaceutical companies time and money.
A team of researchers has revealed the molecular motions behind elastin's flexibility, showing how scissor-shaped molecules assemble into long chains that give tissues their stretchability. The study provides insights into the material's durability and could lead to new materials for engineering applications.
Scientists have created engineered liver tissue that closely mimics the real thing, with a metabolic rate closer to real-life levels than existing models. The new approach successfully simulated how a real liver would react to various drug combinations.
Scientists have developed a method to regrow functional joints in frogs using a 'reintegration' mechanism. This approach could potentially be used to regenerate limbs in mammals and humans. The research paves the way for further studies on functional joint regeneration.
Researchers developed a color-changing indicator that detects small cracks and scratches in polymers, highlighting areas of mechanical damage. The system uses microcapsules with pH-sensitive dyes that change color upon stress or fracture, allowing for early detection and prevention of costly failures.
Researchers discovered that altering poplar wood composition affects tree microbiome structure and function. Modifications led to changes in bacterial communities within the endosphere, but not outside the plant tissue.
A new study by Penn and Delaware researchers sheds light on the mechanics and biology of natural and engineered tissue, informing ways to treat injuries like knee meniscus tears and age-related tissue degeneration. The team developed micro-engineered models that replicate key features of degenerating native tissue, enabling testing of ...
A team of researchers has shed new light on the relationships between cartilage structure and function, revealing microdomains that behave differently from surrounding tissue. This discovery paves the way for more effective treatments of meniscus tears and osteoarthritis.
Researchers have developed new mathematical approaches to understand stem cell function, nutrient signaling, and brain development. The models provide insights into the complex interactions between stem cells and neural tissues, shedding light on phenomena such as differentiation and cortical formation.
The study found that stromal cells, specialized fibers, and T helper 17 cells collaborate to form tertiary lymphoid tissues (TLTs) in the brain of MS patients. This discovery may lead to potential treatment options, such as targeted Th17 blockers, by understanding how TLTs are formed.
Researchers used a novel approach to measure the forces exerted by tumor cells on their surrounding connective tissue. By analyzing tissue deformations, they calculated cell forces with high accuracy, revealing key insights into tumour cell migration and behaviour.
Researchers at Oregon State University have developed a new method for vitrification that minimizes cell damage during the freezing process. This approach has shown significant improvement in healthy cell survival rates, paving the way for wider use of extreme cold preservation for tissues and organs.
University of Wisconsin-Madison scientists successfully grew functional vocal cord tissue in the laboratory using bioengineering techniques. The tissue was able to transmit sound and showed similar characteristics to native tissue, paving the way for potential clinical applications.
Researchers have created a 3D printing technique that produces highly uniform 'blocks' of embryonic stem cells, which can be used as building blocks to construct tissue constructs, larger structures of tissues, and potentially even micro-organs. The method outperforms existing methods in terms of cell uniformity and homogenous prolifer...
Two postdoctoral scholars from UC Santa Barbara's Kavli Institute for Theoretical Physics developed a method called ImSAnE, which constructs an atlas of two-dimensional maps for dynamic tissue surfaces. This allows scientists to analyze layered tissues with relative ease and reduces data size and processing time.
A 125-million-year-old fossilized mammal named Spinolestes xenarthrosus has remarkably preserved fur, hair follicles, hedgehog-like spines, organs, and even a fungal hair infection. The study pushes back the earliest record of preserved mammalian hair structures by over 60 million years.
Researchers at Queen Mary University of London developed a method for self-assembling organic molecules into complex tissue-like structures without moulds or 3D printing. This discovery could enable the engineering of tissues like veins, arteries, or the blood-brain barrier, facilitating disease research and implant development.
Researchers at RIKEN Brain Science Institute developed a new optical clearing technique called Sca l eS, enabling the creation of transparent brain samples for detailed analysis. The technique has provided new insights into Alzheimer's disease pathology and revealed associations between amyloid beta plaques and microglial cells.
EPFL scientists have developed a new method called cryofixation to preserve the brain's true structure, overcoming distortion caused by traditional fixation methods. This breakthrough allows for unprecedented detail in brain imaging and has significant implications for understanding brain anatomy and function.
Breast cancer researchers have gained new insights into the phases of tumor growth by visualizing and quantifying tumor development in real-time. The study reveals that tumors undergo a dramatic increase in cell number after four weeks, providing valuable information for treatment selection and delivery.
Researchers found that an extra set of guanines in our DNA may function like a spare tire to repair damage and prevent cancer. This 'factory-installed safety feature' could be a key to understanding why some people don't develop cancer despite high levels of oxidative stress
Researchers have developed a method to visualize plant branching structures using MRI, gaining insights into the design of lightweight materials. The technique allows for non-invasive visualization of vascular tissues under stress, enabling optimization of branched, fibre-reinforced components in various industries.
A special issue of Calcified Tissue International & Musculoskeletal Research explores the relationship between bone material properties and skeletal fragility. The collection of reviews provides a comprehensive overview of the latest findings on mineral, collagen, and water compartments in bone.
A Northwestern University team developed a novel graphene-based ink that can print large, robust 3D structures while preserving the material's unique properties. The ink allows for the creation of flexible and strong scaffolds that can support stem cells and promote differentiation into neuron-like cells.