Research on weight loss and its health effects. Covers GLP-1 injections, companion digital programs, pregnancy guidelines, and asthma benefits.
A pooled data analysis of 31 clinical trials found that wearable fitness trackers and step counters significantly helped people with weight-related health conditions lose weight. Those using research-grade step counters/accelerometers lost an average of 4.4 kg, while commercial fitness trackers produced a 3 kg loss.
New research from the University of Bath found that females who are physically fitter burn fat more efficiently when exercising compared to males. The study analyzed factors influencing body fat burning during endurance sports and explored molecular mechanisms behind sex differences in fuel use.
A study found that family members of patients following the Mediterranean diet-based PREDIMED-Plus program experienced significant weight loss, averaging almost 4 kg over two years. Improved dietary habits were also observed, with family members showing increased commitment to the Mediterranean diet.
A study by the University of South Australia found that women with gestational diabetes are ten times more likely to develop type 2 diabetes. However, only a third of these women understand they are at high risk due to lack of education and lifestyle changes.
Researchers found that participants with obesity and food insecurity lost less weight than their food-secure counterparts over a 24-month period, despite following an intensive lifestyle-based intervention. The study highlights the need for weight loss approaches that address both obesity and food insecurity.
A recent international study found that semaglutide, an injectable medication, is effective in reducing weight and treating obesity in patients with Type 2 diabetes. The study showed significant weight loss results, with over 25% of participants achieving a 10% or greater weight loss.
Researchers mapped out changes in fat tissue during intermittent fasting, showing visceral 'belly' fat becomes resistant to weight loss by adapting to repeated fasting periods. The study provides insights into the mechanisms behind this resistance and potential diet interventions.
A systematic review of randomized controlled studies found that digital self-monitoring using digital health tools was associated with significant weight loss. Digital tools, including apps, wearables, and websites, were used to track behaviors such as diet and physical activity.
In a groundbreaking 68-week study, semaglutide combined with intensive behavioral therapy resulted in an average weight loss of 16% for participants, exceeding one-third who lost 20% or more of their baseline weight. The treatment also showed significant improvements in cardiometabolic risk factors and marked metabolic benefits.
A study found that bariatric surgery leads to greater weight loss in patients with a heightened perception of sweetness and lower hedonic hunger. Changes in sweet intensity perception were associated with the magnitude of weight loss, while pleasantness had no correlation.
A new study found that a vegan diet is more effective than the Mediterranean diet for improving health markers and boosting weight loss. Participants who followed a low-fat vegan diet lost an average of 6 kg and had significant reductions in visceral fat, total and LDL cholesterol levels.
A pilot study of time restricted eating found that participants lost an average of 3.5kg over 12 weeks with almost 60% adhering to the plan at three months. The researchers suggest this weight loss approach could be a viable option for those struggling with obesity.
A University of Alberta study finds that weight loss before knee replacement surgery does not lead to better outcomes for patients with advanced knee osteoarthritis. The research calls into question the use of body mass index (BMI) as a determinant of patient outcomes, highlighting the need to reconsider recommendations about BMI.
A low-carb diet may lead to higher rates of type 2 diabetes remission in the short term, with benefits diminishing at 12 months. The study found that low-carb diets increased weight loss and reduced medication use, but also showed worsening quality of life and cholesterol levels at longer term.
A new study found that many weight loss surgery patients in the UK are not receiving annual nutritional monitoring and weight checks as recommended by clinical guidelines. This can lead to serious health consequences, including weight regain and nutrient deficiencies. The study's lead researcher calls for improved support for GPs and p...
A Drexel University study found that health counselors with access to self-monitored health data helped participants maintain weight loss. The study involved 87 adult participants who shared their daily activity, food intake, and weight using wearable devices and smartphone apps.
A recent study found that formulating New Year's resolutions as 'approach goals' (adopting new habits) leads to higher success rates than 'avoidance goals' (quitting or avoiding something). Rephrasing resolutions can also boost success, especially when replacing unhealthy habits with healthier ones.
A new study published in the Journal of Bone and Mineral Research found that exercise can help minimize bone loss after weight loss surgery. Participants who attended structured exercise sessions had higher bone mineral density measurements compared to those in the control group.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that gastric bypass surgery can lead to long-term diabetes remission in over half of adults with type 2 diabetes. The study suggests that weight loss is not the only factor contributing to improved blood sugar levels.
A study published in Annals of Internal Medicine found that nearly 40% of US adults with overweight and 10% with obesity do not consider themselves overweight. This lack of self-awareness is linked to lower attempts to lose weight and contributes to rising obesity rates.
Researchers at Children's Hospital Colorado found that 80-90% of adolescents experience remission of obesity-related complications after bariatric surgery. The study suggests that patients' health improves regardless of whether they sustain high levels of weight loss long-term.
A recent study has found that sleeve gastrectomy in adolescents leads to a significant increase in bone marrow fat and a decrease in bone density. The procedure, which restricts food intake, causes the stomach to take on a tube-like shape, leading to weight loss of up to 75 pounds.
Pitt researchers found that insufficient social support and unrealistic weight loss expectations can predict dissatisfaction with Roux-en-Y gastric bypass surgery. Higher physical activity levels after surgery improve mental and physical quality of life, regardless of weight loss.
A new University of Warwick-led study found that obese patients over 60 years old can lose an equivalent amount of weight as younger people through lifestyle changes alone. The research aims to correct misconceptions about the effectiveness of weight loss in older people and promote healthy ageing.
A recent UCL-led study found that UK teenagers are increasingly dieting to lose weight, with girls being more likely to experience depressive symptoms. The research also showed that boys are becoming more likely to try to gain weight, and both sexes are overestimating their weight.
A new study published in the American Journal of Transplantation shows that simultaneous robotic-assisted kidney transplant and weight loss surgery is safe for obese patients. The procedure resulted in a significant reduction in surgical complications and improved cardiac function, with all patients experiencing a substantial weight loss.
A study suggests that losing fat mass, but not lean mass, is key for heart health in obese patients with type 2 diabetes. Reducing body fat and waist circumference lowers the risk of heart failure in this population.
A study found that weight and blood pressure were reduced regardless of when participants ate, challenging the idea that eating earlier affects energy usage. Researchers followed 41 overweight adults for 12 weeks and saw no difference in weight loss between those who ate most calories early or later.
Researchers found that nearly 19% of US children and adolescents are obese, with severe obesity rates higher in Hispanic and Black youth. Bariatric surgery is a safe and effective option for treating these patients, but many are not being offered the treatment due to lack of access.
A study by researchers at Ben-Gurion University found that a neural subnetwork of connected brain regions correlates with future weight loss. The team identified the stomach basal electric rhythm as a key factor in weight loss, suggesting that visual information may play a role in triggering eating.
Controlling blood sugar levels boosts cognitive function, including thinking, learning, and remembering. However, more weight loss and exercise only improve executive function skills, while verbal learning and memory decline. Effective management of type 2 diabetes is crucial to offset its negative effects on brain health.
A randomized clinical trial found that restricting daily eating to between 12 pm and 8 pm resulted in significant weight loss among participants. The study also showed improvements in metabolic markers, suggesting a potential therapeutic strategy for obesity.
A study by Cleveland Clinic found that surgically induced weight loss of 5-10% improves life expectancy and cardiovascular health. The research suggests metabolic surgery may contribute to health benefits independent of weight loss.
Patients with the highest obesity risk who received a tailored coaching program lost 5% of their body weight, compared to 0.5% in usual care group. The study demonstrates the importance of convenient and accessible interventions in overcoming barriers to weight loss.
A study of UK data from the ACTION-IO study found that individuals with obesity waited an average of 9 years before discussing weight loss with their healthcare provider, significantly longer than the global average. This delay increases the risk of developing related health conditions such as type 2 diabetes and cancer.
A COVID-19 vaccine candidate has been shown to prevent severe clinical disease in animals, including weight loss, pneumonia, and death. The vaccine elicited a robust immune response and protected non-human primates and Syrian golden hamsters against SARS-CoV-2.
A study of over 550,000 adults in the UK found that losing an average of 13% of body weight reduced the risk of developing type 2 diabetes by 42%-44%, sleep apnoea by 22%-27%, high blood pressure by 18%-25%, and dyslipidaemia by 20-22%. The study suggests that intentional weight loss can markedly reduce disease risk in people with obes...
Researchers found that these diets help with short-term weight loss, but may not be effective in preventing heart disease. Established nutritional guidelines are recommended for better cardiovascular health, according to the study.
A recent study found that couples who worked on healthy habits together had better chances of losing weight, especially when they participated in lifestyle programs. The study, which analyzed data from over 400 patients, showed that having a partner with similar lifestyles helped maintain motivation and overcome practical challenges.
A new study published in Gastroenterology found that consuming frozen microbiome capsules derived from their own feces when dieting may limit weight regain. Participants who followed a green-Mediterranean diet and received fecal microbiome transplantation lost more weight and regained less weight compared to those on other diets.
A new study published in Obesity found that an intensive lifestyle intervention (ILI) focused on weight loss lowered the incidence of obesity-related cancers in adults with overweight or obesity and type 2 diabetes. The ILI reduced cancer incidence by 16% compared to a Diabetes Support and Education comparison group.
New research from WashU Medicine finds that weight loss after surgery, not the surgery itself, drives improvements in metabolism and remission of diabetes. The study compared patients who lost weight through gastric bypass surgery with those who achieved equivalent weight loss through diet alone.
A new clinical guideline recommends treating acute pain from non-low back musculoskeletal injuries with topical NSAIDs, suggesting against opioid use. The guideline focuses on effective treatments and suggests oral NSAIDs, acetaminophen, acupressure, or transcutaneous nerve stimulation for patients.
Researchers at Lund University found that a strict six-week low-calorie diet had the greatest positive effect on health markers after bariatric surgery. The operation itself caused minor changes, and most effects disappeared after six weeks.
A pilot study found that Australian men who participated in a sports-themed weight loss program increased physical activity and lost more weight compared to those in the control group. The program, which included 12 weekly sessions, was deemed feasible and cost-effective.
Research published at the American Heart Association's Basic Cardiovascular Sciences 2020 Scientific Sessions found that weight loss is not always the best strategy to enhance aerobic fitness in young women. In fact, a lower body mass index (BMI) may be aerobically counterproductive for many women under 30, who still have high aerobic ...
Researchers investigate how excessive exercise affects emotional states in people with eating disorders, aiming to develop personalized interventions. The study also seeks to understand individual differences in triggering excessive exercise and its impact on recovery duration.
A new study published in Cell Metabolism found that two daily fasting diets, with eating windows of 4-6 hours, can lead to significant weight loss and improved cardiometabolic risk factors. Participants lost about 3% of their body weight by reducing calorie intake and showed reduced insulin resistance and oxidative stress levels.
A new Northwestern Medicine remote weight-loss program, Opt-IN, helped participants lose 11-13 pounds, matching the success rate of the gold-standard National Diabetes Prevention Program. The program is cheaper and less burdensome than traditional treatments, making it more accessible and affordable.
A new study from the University of Georgia finds that bariatric weight loss surgery is more expensive for public insurance patients compared to private insurance. The study analyzed a national dataset and found that Medicare patients paid the highest average cost per surgery, while publicly insured patients paid more overall.
A new study finds that social interactions with top performers have a positive impact on weight loss success, while those with average performers have a negative effect. The study suggests using the successes of top performers to inspire dieters and avoid using overall group success as a benchmark.
A new drug lead has been developed to treat type 2 diabetes, improving blood sugar levels without nausea and weight loss. The research combines two molecules using a novel technique called 'corrination', reducing vomiting compared to existing GLP-1R agonists.
Research highlights the importance of balancing healthy eating with nutrient-dense diets to avoid deficiencies. A new study also links weight loss diets to a higher risk of orthorexia nervosa, while another study suggests that gut microbes may play a role in predicting weight loss success.
A study published in Journal of Internal Medicine found that weight loss surgery changes gene expression in fat tissue, leading to metabolic improvements and reduced type 2 diabetes risk. These changes persisted even after weight regain, suggesting a long-term impact on health outcomes.
A new study published in Cell Metabolism found that disulfiram, normally used to treat alcohol use disorder, can help obese mice normalize their body weight and reverse metabolic damage. The drug's anti-inflammatory properties are believed to be key to its beneficial effects.
A study of nearly 500,000 patients found that significant weight loss before bariatric surgery was associated with a higher risk of death within 30 days after surgery. Researchers examined the correlation between pre-surgery weight and post-operative mortality in patients undergoing bariatric surgery.
A new study from the University of Gothenburg finds that weighted vests can lead to a reduction in body weight and fat mass, particularly when wearing heavy weights, while maintaining muscle mass. The researchers suggest that this is due to a built-in energy balance system that endeavors to keep body weight constant.
Researchers found that women who made lifestyle modifications in middle age reduced their long-term risk of total stroke by nearly a quarter and ischemic stroke by more than one-third. Engaging in daily exercise and quitting smoking were estimated to reduce the risk of total stroke by 25% and ischemic stroke by 36%.
A comprehensive analysis of 121 randomised trials found that most diets result in modest weight loss and improvements in cardiovascular risk factors over six months. However, the benefits often disappear at 12 months, except for the Mediterranean diet which saw a small reduction in LDL cholesterol.
A new study published in the Journal of the Endocrine Society found that people with very poor fitness at the beginning of a behavioral weight loss program lose less weight in the long term. Adults with poor or better fitness lost nearly twice as much weight over 18 months compared to those with very poor fitness.