A new smartphone app designed for breast cancer survivors has been shown to help patients achieve significant weight loss and improvements in physical activity. The app, created at Houston Methodist, allows users to interact with their healthcare team and receive real-time feedback and guidance from a clinical dietitian.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism reveals weight cycling is associated with a higher risk of death. Conversely, weight loss from weight cycling can reduce diabetes risk in people with obesity.
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A survey of 800 adults undergoing bariatric surgery found that patients prioritize expected out-of-pocket costs and weight loss potential. This approach may differ from the procedure's related risks or recovery time. The study suggests healthcare providers should discuss cost with patients to ensure informed decision-making.
A new study published in Obesity found that children and adolescents with common obesity gene variants can still lose weight through lifestyle interventions. The researchers examined 754 participants, aged 11.6 years, who underwent a series of behavioral lifestyle changes, including dietary changes, physical activity, and sleep habits....
A recent study published in the American Journal of Clinical Nutrition found that intermittent fasting has no advantage over conventional calorie restriction diets for weight loss and improved health outcomes. The HELENA study, which followed 150 overweight participants for a year, showed similar results for both dietary methods in ter...
Researchers found African Americans had significantly more weight regain than Caucasians, while both groups experienced rapid weight gain over time. The study highlights the need for future research into racial differences in bariatric surgery outcomes.
A study by Boston Children's Hospital found that low-carb diets increase the number of calories burned, providing a new approach to treating obesity. The study, which controlled participants' diet for 20 weeks, showed significant differences in calorie expenditure between high- and low-carbohydrate diets.
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Researchers found that low-carb diets resulted in significantly greater energy expenditure compared to high-carb diets. Participants on the low-carb diet burned an average of 209-278 kilocalories per day more than those on the high-carb diet, leading to improved weight loss maintenance.
A new study published in the journal Nutrients found that diet fluctuations can lead to a rollercoaster of risk factors for cardiovascular disease and diabetes. Repeated attempts at adopting a healthy eating pattern can have benefits, with significant improvements in blood pressure and cholesterol levels seen after just a few weeks.
Researchers found four groups of patients with unique characteristics, including disordered eating behaviors and varying levels of glucose in their blood. The study suggests personalized approaches to treating obesity may be more effective, as one-size-fits-all treatments may not work for all individuals.
A new Penn Medicine study found that intensive behavioral therapy (IBT) is effective in achieving clinically significant weight loss in adults with obesity, with participants losing an average of 6.1% of their initial body weight at one year. The study also showed improvements in blood pressure and cardiovascular risk factors.
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Researchers found that people who weighed themselves daily or almost daily had a significant weight loss of 1.7 percent in 12 months, while those who never used at-home scales did not lose weight. Daily weighing may increase awareness of behavior changes affecting weight loss.
A study of over 600 patients with overweight or obesity found that a hypocaloric Mediterranean diet combined with daily exercise maintained clinically significant weight loss after one year. Patients showed improvements in glucose metabolism and inflammatory markers, while those with diabetes saw particularly high benefits.
Adults with severe obesity experienced greater initial and sustained weight loss with gastric bypass surgery compared to sleeve gastrectomy or adjustable gastric banding. The study, involving over 46,000 patients, found that gastric bypass led to a 19-pound weight loss difference at 5 years.
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The American College of Physicians (ACP) has updated its policy recommendations for reducing gun-related injuries and death in the United States. The new guidelines build on existing policies, focusing on a public health approach to address this epidemic of gun violence.
Lifestyle interventions, medication, and surgery can effectively delay or prevent type 2 diabetes in the majority of patients, but limited access to these treatments is a major issue. Evidence-based interventions show that weight loss through lifestyle changes or metabolic surgery can reduce the risk of diabetes by up to 78%.
A study of obese women who underwent gastric sleeve or bypass surgery found that weight loss reversed precancerous tissue changes in the womb. By 12 months after surgery, high-risk changes had reversed and no further pre-cancerous changes were detected.
Researchers at the University of Copenhagen have developed a new treatment that stimulates the body's cold and nicotinic receptors to improve metabolism, suppress appetite, and promote weight loss. The treatment, tested on mice, results in a 12% weight loss over 20 days.
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Low-income obese patients lost a clinically meaningful amount of weight using a free phone app and coaching calls in a primary care clinic. The study found that 43% of participants lost more than 5% of their body weight, while 56% reached a healthy weight loss threshold.
Among pediatric patients aged 20 or younger, there was a notable increase in vertical sleeve gastrectomy and a decrease in laparoscopic Roux-en-Y gastric bypass procedures between 2005-2014. The use of adjustable gastric bands also decreased during this time period, reflecting trends seen in adult metabolic bariatric surgery procedures.
A study published in Cell Metabolism found that individuals who achieved greater weight loss showed increased activity in the lateral prefrontal cortex associated with self-control. Additionally, the hormone leptin returned to baseline levels after successful weight loss, indicating a new set point was achieved.
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A recent analysis of published studies found that preoperative weight loss interventions do not significantly reduce post-surgical risks in obese patients. Lifestyle changes leading to modest weight loss have been shown to be ineffective in reducing morbidity and mortality during and after surgery.
A study by University of Pittsburgh researchers found that measuring percentage of weight regained after bariatric surgery can help predict serious health problems. The rate of weight regain was highest in the first year following maximum weight loss, indicating early detection and treatment may be crucial.
A study published in CANCER found that weight loss in postmenopausal women is associated with a 12% lower risk of invasive breast cancer. Women who lost 5% of their body weight had a lower risk, while those who gained weight had an increased incidence of triple negative breast cancer.
A study funded by NIH found that gastric banding is as effective as metformin in stabilizing disease for people with prediabetes or new-onset type 2 diabetes. Participants who underwent gastric banding surgery lost significantly more weight and showed similar improvements in insulin sensitivity compared to those taking metformin.
A new study published in The Lancet found that lorcaserin, an appetite-suppressant drug, decreases the risk of developing diabetes and increases the rates of remission of high blood sugar in obese and overweight patients. Lorcaserin also reduces the risk of kidney complications due to diabetes.
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The CAMELLIA-TIMI 61 trial found that lorcaserin reduced the risk of diabetes by 19% in patients with pre-diabetes, induced remission in patients with diabetes, and reduced diabetic microvascular complications. Lorcaserin also significantly increased rates of diabetes remission and reduced the risk of severe hypoglycemia.
Researchers found that obese patients who underwent a combined liver transplant and weight-loss surgery experienced significant weight loss maintenance and reduced metabolic complications. The study suggests that this dual approach is safe and effective over the long term for treating obesity-related liver disease.
A new six-year single-center study found a web-based program to be an effective approach to manage lifestyle changes in patients with NAFLD, comparable to group-based interventions. The web program reduced weight loss and improved liver health, suggesting counseling as a key therapeutic option until drugs are approved.
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A new study suggests that weight loss can put type 2 diabetes into remission by improving pancreatic beta cell function. Nearly half of participants who lost fat from around the liver and pancreas achieved diabetes remission, compared to six in the control group.
A multi-center study of adolescents reveals that bariatric surgeries like gastric bypass and sleeve gastrectomy lead to substantial weight loss, while adjustable banding is less effective. The study, which included 544 teens, found comparable weight loss outcomes for gastric bypass and sleeve procedures.
An observational study by researchers at Karolinska Institutet in Sweden found that bariatric surgery is associated with fewer complications during childbirth, including reduced risk of post-term delivery or uterine inertia. The study compared deliveries in women who had undergone weight loss after bariatric surgery to those who did not.
A new study shows Functional Imagery Training (FIT) significantly increases weight loss by 5 times compared to Motivational Interviewing (MI). Participants who used FIT lost an average of 4.11kg in six months and continued to lose weight after the intervention ended.
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Researchers found that online participants lost an average of 10.3 pounds at 6 months and 8.8 pounds at 12 months, comparable to in-person program results. The online program also showed better participation rates than the in-person program.
The USPSTF recommends intensive behavioral interventions focusing on dietary changes and increased physical activity for adults with a BMI of 30 or higher. Obesity is associated with increased risks of coronary heart disease, type 2 diabetes, various types of cancer, disability, and death, particularly among adults younger than 65 years.
A new guideline published by the American Thoracic Society recommends weight loss strategies for adults with obstructive sleep apnea, particularly those who are overweight or obese. The guideline suggests comprehensive lifestyle interventions and behavioral counseling to help patients achieve weight loss.
Researchers found that patients who experienced a shift from sweet and fatty food preferences to bitter tastes after bariatric surgery lost the most weight. These altered preferences were temporary and generally returned to pre-surgery levels over time, but the majority of patients successfully maintained their weight loss.
Research found that even moderate weight loss (20+ pounds) over 20 years increases risk of death by 74%, while greater weight variability is associated with poor physical function. Long-term weight loss may be a marker for increased health decline in older women.
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A recent study published in the New England Journal of Medicine found that lorcaserin, a weight loss drug, helped patients lose weight without increasing the incidence of heart attacks, strokes, and death from heart disease. The trial involved 12,000 overweight or obese patients at risk for cardiovascular events.
A weight loss drug, lorcaserin, does not increase the risk of cardiovascular events, according to a study that enrolled over 12,000 adults. The trial found noninferiority of lorcaserin for major adverse cardiovascular events compared to placebo after three years.
Scientists have identified a brain receptor protein that controls the body's 'fat rheostat', regulating energy balance and weight gain. The discovery opens new doors for developing anti-obesity drugs, particularly targeting the melanocortin 3 receptor (MC3R) to treat obesity.
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A new study by the University of Texas Health Science Center at Houston found that Americans who lost more than a fifth of their body weight experienced a significant improvement in metabolic health, with those losing 5-10% showing a 22% lower risk of metabolic syndrome.
A recent study found that gastric bypass surgery increases the risk of fractures, particularly in individuals without diabetes. The researchers compared data from over 38,000 patients who underwent gastric bypass operations with a control group and found a significant increase in fracture rates, with risks ranging from 26% to 32%.
A study found that resistance training may help minimize bone loss associated with active weight loss in older adults. However, the results suggest that additional intervention strategies are needed to maximize skeletal benefit and preserve overall bone health.
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A recent study found that nearly half of individuals with type 2 diabetes achieved remission after a weight-loss intervention. The research suggests that substantial weight loss at diagnosis can rescue beta cells and reverse the condition. However, only those who experienced early and sustained improvement in beta-cell function were ab...
A Mayo Clinic study found that specific gut bacteria, such as Phascolarctobacterium and Dialister, are associated with weight loss success and failure, respectively. The research suggests that individualized strategies may be needed to address the unique metabolic needs of each person.
A new study published in Annals of Surgery found that bariatric surgery wait times in the US have increased significantly over the past decade, with eligible patients often facing longer waits. The delay is largely attributed to insurers requiring patients to lose weight before surgery, which can deter some individuals from pursuing th...
Researchers observed red-fronted lemurs in Madagascar chewing on millipedes to rid themselves of intestinal parasites. The animals then rubbed the area around their genitals, anuses, and tails with the chomped millipedes to treat conditions like itching and weight loss.
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A novel drug, Metabocin, based on capsaicin has reversed damaging effects of high fat diet in mice, improving blood sugar, cholesterol levels, insulin response, and symptoms of fatty liver disease. Long-term use of the drug showed no adverse effects or weight regain.
A new study found that low-carb diets can improve artery flexibility in women, even if men lose weight more, suggesting a potential benefit for pre-diabetic women. This improvement in artery flexibility reduces the risk of developing serious heart conditions.
A new diabetes diagnosis can lead to higher rates of healthy behaviors among a patient's partner, including weight management and smoking cessation. Partners with newly diagnosed diabetics exhibited greater behavioral change even when clinicians didn't focus on them.
A web-based health behavior change support system improved weight loss and waist circumference reduction for up to 2 years. HBCSS, combined with cognitive behavioral group therapy or as a standalone treatment, offers a personalized approach to obesity treatment.
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A series of setbacks can lead to an 'action crisis,' causing individuals to question the importance of their goal. New research reveals that repeated struggles and setbacks can cause people to devalue their goal, making it harder to stick to it. However, knowing ahead of time when an action crisis may occur allows individuals to prepar...
Research highlights how normalizing plus-size body shapes can lead to underestimation of weight, undermining efforts to tackle obesity. The study shows that socioeconomic inequalities play a significant role in patterns of weight misperception.
Atrial fibrillation, Australia's most common heart rhythm disorder, can be alleviated by losing weight and treating lifestyle factors. Obesity is a leading cause of stroke and heart failure, but research shows that reducing weight by 10% can reverse the progression of the disease.
A new study from MIT and Dana-Farber Cancer Institute found that pancreatic tumors can cause weight loss due to reduced digestive enzymes, but treatment with enzyme replacement did not improve survival. The researchers suggest a potential protective mechanism underlying this process.
People with severe obesity report using various weight loss methods, but none prove more effective than maintaining lower caloric intake. Weight loss surgery is a proven method for reducing weight in the long term and lowering disease risk, but not suitable for everyone.
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Researchers found that a weight loss of 20% or more leads to improved physical health-related quality of life, reduced pain, and better function. Additionally, this significant weight loss results in an additional 25% reduction in pain compared to a 10-19.9% weight loss.
Researchers found that participants who followed a 16:8 diet consumed fewer calories, lost weight, and had improvements in blood pressure. The study suggests that daily fasting is an effective tool for weight loss in obese adults.
Researchers found that gastric bypass surgery leads to rapid initial weight loss, but subsequent muscle mass is maintained over five years. The study dispels fears of long-term muscle insufficiency despite weight regain.