Research on weight loss and its health effects. Covers GLP-1 injections, companion digital programs, pregnancy guidelines, and asthma benefits.
Researchers at University of California - Riverside are studying the keto and intermittent fasting diets on a molecular level, finding that women may metabolize fat differently than men. The study aims to understand why keto diet may not be effective for women and how it affects their overall health.
A University of Gothenburg study found that bariatric surgery lowers cancer risk by 60% in obese patients with type 2 diabetes, particularly those achieving and maintaining normal glucose control. The research highlights the importance of glucose control in preventing cancer in this high-risk population.
A new study found that consuming prunes can help regulate appetite and lead to greater weight loss compared to other snack choices. Prune consumption was also associated with improved satiety and reduced hunger levels, making them a potential strategy for managing holiday cravings.
Researchers found that video-based, telehealth-delivered exercise and weight loss programs improved pain and function in people with knee osteoarthritis and overweight or obesity. The intervention with dietary component led to substantial weight loss and additional benefits.
A new study published in Medicine & Science in Sports & Exercise found that exercising intensely at the start of a fast can maximize health benefits by speeding up the transition to ketosis. Participants who exercised reached ketosis on average three and a half hours earlier, producing 43% more B-hydroxybutyrate.
A new study found that low energy diets with formula meal replacements are the most effective methods for weight management and remission in adults with type 2 diabetes. Formula meal replacements achieved greater weight loss compared to food-based low-energy diets.
A clinical trial found that long-term weight loss was similar for those who received 5:2 diet or standard weight management advice, with 18% and 15% of participants losing at least five per cent of their body weight. However, the 5:2 diet group was more likely to recommend the intervention to others or continue with it.
New research from the University of South Australia finds that the 5:2 diet is just as effective as a continuous energy-restricted diet in achieving weight loss and preventing type 2 diabetes in women with a previous diagnosis of gestational diabetes. The study suggests that this diet offers greater choice and flexibility for women loo...
A recent study by the University of California - San Diego team discovered that glycogen regulates and promotes fat metabolism, helping to balance energy intake and expenditure. The research suggests modulating glycogen metabolism in fat cells could provide new approaches for weight loss and improved metabolic health.
About 42% of U.S. adults are considered clinically obese due to increased risk of health conditions such as diabetes and heart disease. New weight-loss drugs like Wegovy (semaglutide) show promise in safely aiding weight loss, but long-term side effects and sustainability remain concerns.
The MUSC Hollings Cancer Center researchers are exploring the role of macroenvironment in pancreatic cancer-induced cachexia to address this debilitating condition. The team aims to provide new biological insight, which will be coordinated by four cores within the program project grant.
A clinical trial found that a green Mediterranean diet rich in leafy greens like Mankai and green tea can elevate fasting ghrelin levels, reducing belly fat and improving insulin sensitivity. This approach may also have additional cardiometabolic benefits.
Researchers found that eating high-fibre whole grain rye products resulted in greater weight loss and body fat reduction compared to refined wheat alternatives. The study, involving 242 participants, suggests that rye's unique fibre content may contribute to its weight-loss benefits.
A review of 25 studies on intermittent fasting found that all forms produced mild to moderate weight loss, similar to traditional calorie-restrictive diets. Intermittent fasting regimens also showed benefits in decreasing blood pressure and insulin resistance, and improving appetite regulation.
Researchers found that young male winter swimmers had better thermoregulation and higher heat loss due to frequent sauna exposure. They also showed increased brown fat tissue activity, particularly in response to cold exposure.
A new study finds that bariatric surgery increased among lower-income white adults, but remained unchanged for Hispanic and Black adults following Medicaid expansion. The increase in weight-loss surgery rates is a significant finding with implications for health policy.
A recent study by Michigan Medicine found that sleeve gastrectomy is associated with lower risks of death and complications compared to gastric bypass surgery. However, patients who underwent sleeve gastrectomy were more likely to require follow-up surgery.
Cachexia is characterized by weight loss and muscle tissue shrinkage, driven by the immune system's response to chronic infections and diseases. Researchers from CeMM emphasize the need for more research into cachexia, highlighting the importance of interplay between the immune system and metabolism.
A study found that people living with overweight or obesity experience lower levels of care across eight quality markers, including emotional support and fast access. Healthcare professionals often make rude comments about weight, contributing to poor experiences.
A multidisciplinary taskforce developed a Clinical Care Pathway for NAFLD/NASH, outlining practical guidance from screening to patient care management. The pathway aims to provide efficient, safe, and value-based care for patients with NAFLD and NASH, highlighting the importance of early interventions and shared decision-making.
A new USC study found that artificial sweeteners like sucralose can trick the brain into feeling hungry, leading to increased calorie consumption. This study, one of the largest to-date on artificial sweeteners, suggests that females and people with obesity may be more sensitive to these sweeteners.
Problem-solving therapy led to short-term changes in the amygdala, a key region for emotion regulation, in individuals with comorbid depression and obesity. The study suggests that neural target changes at two months predicted improved behavioral outcomes after 12 months.
A new study found that people of normal weight with type 2 diabetes can achieve remission by losing weight. Eight out of 12 participants achieved remission after losing 10-15% of their body weight, with levels of fat in the liver and pancreas falling substantially and insulin-producing cells restored. The study supports the idea that e...
A recent US study found that major weight loss can reverse most cardiovascular risks associated with obesity. The study analyzed data from over 20,000 adults and found that the risk of high blood pressure and dyslipidemia was similar in those who lost weight and those who never had obesity.
A new UNSW Sydney-led study suggests that strength training can lead to significant weight loss, with participants losing an average of 1.4% of their total body fat after a five-month program. The study analyzed existing evidence and found that this level of fat loss is comparable to cardio-based exercise.
Increasing physical activity and improving fitness are superior to weight loss in reducing mortality risk and treating obesity-related health conditions. Employing a weight-neutral approach also reduces the risks associated with yo-yo dieting.
A pilot study at the University of Cincinnati found that young adults with ASD and ID can lose or maintain weight with a system of education and support in place. Participants and parents reported knowledge and behavior change, with two participants losing significant weight.
A new study from Institute for Systems Biology (ISB) reveals that the genetic capacity of the gut microbiome is strongly associated with weight loss success or failure. Microbiomes of those who lost weight had higher bacterial growth rates and were enriched in genes that divert dietary nutrients toward bacterial cell growth. In contras...
Top-performing diet and nutrition apps often track dietary intake, anthropometrics, and physical activity but lack behavior change features. A new study in the Journal of Nutrition Education and Behavior found that premium versions offered more features than free ones, but these did not significantly impact app ratings or user engagement.
A new study from NYU Langone Health found that losing weight and managing excess body fat can significantly reduce the risk of lung disease in firefighters exposed to toxic substances on 9/11. The study analyzed 20 years of data from over 5,700 first responders and identified five key factors that predict lung disease.
A large-scale review of clinical evidence suggests that losing significant weight through diet or surgery can bring about type 2 diabetes remission. Meal-replacement diets and low-carbohydrate diets were found to be effective in achieving remission, with people who lost the most weight being more likely to succeed.
A recent study published in Current Biology found that individuals with obesity burn fewer calories on body maintenance when exercising, reducing the calorie-burning gains of exercise. This reduction in energy expenditure was most pronounced in individuals with obesity and older adults.
A study published in Current Rheumatology Reviews found that rehabilitation exercises significantly improved functional strength and reduced weight in knee osteoarthritis patients. The researchers also noted an increase in exercise adherence among the rehabilitation group compared to the control group.
Research suggests that dieting is a consequence of an unhealthy food environment, rather than the cause of weight loss problems. Experts recommend refocusing concerns on changing the food environment to curb dieting and related issues.
A new study by Salk scientists found that time-restricted eating (TRE) confers multiple health benefits, including reduced risk of type 2 diabetes, fatty liver disease, and sepsis, regardless of age and sex. TRE may also protect against infectious diseases like COVID-19 and improve insulin resistance.
Patients who underwent bariatric surgery reported improved physical health, energy, and reduced body pain compared to those on medical therapy alone. Significant weight loss and insulin independence drove these improvements in general health measures and quality of life.
A study by Cleveland Clinic found that combining a weight management program with FDA-approved anti-obesity medications leads to significant weight loss among adults with obesity. The research showed that participants who had access to the medications averaged -7.7% weight loss at 12 months, compared to -4.2% in those without medication.
A University at Buffalo-led study found that SGLT2 inhibitors cause a median weight loss of over 6 pounds in Type 2 diabetes patients, compared to 2.5 pounds with GLP-1 receptor agonists. The findings suggest that SGLT2 inhibitors may be more protective against weight gain caused by other antidiabetic drugs.
A comprehensive review of 315 clinical trials found that most weight-loss supplements and therapies did not produce significant weight loss. Only 16 studies demonstrated significant results, with weight loss ranging from 0.3 to 4.93 kg.
Researchers found that extreme caloric restriction diets alter the gut microbiome, leading to weight loss in participants. The study suggests that a decrease in gut bacteria and an increase in Clostridiodes difficile may be responsible for the observed weight loss effects.
A new study suggests that alternate-day intermittent fasting may offer no unique health benefits over a standard daily diet. In contrast, traditional daily energy restriction resulted in greater weight and fat loss. The researchers note that longer studies with larger groups are needed to confirm these findings.
A new study published in Science Translational Medicine found that intermittent fasting diets are not the most effective way to lose weight. Participants who followed a traditional diet with reduced calorie intake lost more weight and fat mass compared to those who fasted on alternate days.
A study by Brigham and Women's Hospital found that patient-provider discussions about bariatric surgery result in patients with obesity losing more weight; however, such discussions occur in less than 10% of eligible cases. Patients who had these conversations were 10 times more likely to undergo weight loss surgery.
A new study suggests that using a brain-training app can help people reduce their junk food consumption and lose weight. The app trains users to associate healthy foods with stopping and unhealthy snacks with avoiding, resulting in an average weight loss of half a kilogram and a small increase in healthy food eaten.
A recent study by the University of Washington found that living in a more densely populated neighborhood is associated with lower body weight and less obesity. However, proximity to fast-food restaurants or supermarkets did not have a significant impact on weight gain.
A study conducted in Brazil found that a cognitive-behavioral approach to treatment can significantly yield weight loss and improve quality of life. The program was shown to be effective in increasing quality of life in all domains, physical, psychological, social, and environmental, while reducing symptoms of depression.
A double-blind study found that combining endoscopic sleeve gastroplasty (ESG) with semaglutide increased weight loss in patients, with the ESG group losing an average of 26.7% of their total body weight compared to 19.6% for the control group.
A new study has found a reduced risk of eye cataracts associated with obesity surgery. Patients who underwent weight loss through bariatric surgery showed a lower incidence of cataract compared to those who did not have surgery, especially when performed before age 60.
Researchers found that semaglutide treatment leads to significant weight loss across various patient groups, including those with different ages, sexes, and body weights. Female participants and those with lower starting body weights achieved the most substantial weight losses.
A new study found that semaglutide causes similar weight loss in patients aged under 40, 40-60 years, and 60 years and over. The treatment also showed a more pronounced effect on body composition in younger patients.
A virtual weight-management support group during lockdown resulted in clinically meaningful weight loss for 27% of participants, associated with reduced risk of diabetes and other chronic conditions. Average weight loss was 7.4lbs or 3.5% of body weight.
The COVID-19 pandemic's restrictions both spurred motivation and supported participation in an online weight management program, yet had a negative impact on mood and behaviors. Participants attributed lockdowns to weight gain and found the pandemic motivated them to lose weight, but also reported decreased social support.
A global review of 121 randomised trials involving nearly 10,000 adults found herbal and dietary supplements show statistically greater weight loss but not enough to benefit health. The authors call for more research into long-term safety due to lack of clinical evidence supporting their effectiveness.
A new study by University of Copenhagen researchers reveals the key to maintaining long-term weight loss in people with obesity. Combining moderate-intensity exercise with appetite-inhibiting medication yields significant health benefits, including reduced blood sugar levels, improved fitness ratings, and muscle mass preservation.
Researchers found that consuming mixed tree nuts resulted in significant weight loss and improved satiety, while also reducing dropout rates compared to pretzel snacks. The study suggests that incorporating tree nuts into a weight management program may have a positive impact on overall health.
A study published in JAMA Neurology found that weight loss surgery is more effective than dieting in reducing brain pressure in patients with idiopathic intracranial hypertension (IIH). Bariatric surgery resulted in a significant reduction of brain pressure and weight loss, with the surgery group losing an average of 23Kg after 12 months.
A recent study published in Nutrients investigated the influence of exercise on food intake. The results showed that physical activity increased the amount and urgency of food consumption, particularly after exercise. This finding highlights the importance of considering post-exercise eating habits for optimal weight loss.
The American Gastroenterological Association has released new clinical guidelines recommending the use of intragastric balloons for patients with obesity who have not been able to lose weight with traditional strategies. The treatment is most successful when combined with lifestyle modifications and pharmacological agents, and can be u...
Researchers tested 17 supplements containing deterenol and found nine experimental stimulants, linked to nausea, vomiting, and cardiac arrest. Consumers are urged to avoid these products and report any adverse effects to medical authorities.
Researchers found that dieting impairs the energy-producing machinery of fat tissue, resulting in rapid weight regain, whereas bariatric surgery improves mitochondrial function and reduces regaining weight. The study used transcriptomics analysis to examine the effects of dieting and surgery on adipose tissue mitochondria.