Research on weight loss and its health effects. Covers GLP-1 injections, companion digital programs, pregnancy guidelines, and asthma benefits.
A study found that competition preparation temporarily reduces resting energy expenditure in physique athletes, primarily due to reduced energy intake and lower levels of thyroid hormone T3. This reduction can complicate weight loss and make it difficult for athletes to compete.
A study found that unintentional weight loss in people with Down syndrome coincides with brain changes associated with Alzheimer's disease, indicating it could be an early predictor. The researchers suggest that weight loss may be a useful tool for making an earlier diagnosis.
A new study found a significant weight loss of 8.8% among participants after six months, with improvements in health and vitality. The approach addresses biological antecedents of food intake and develops intrinsic motivation for behavior changes.
Research published in BMJ Open found that carrying excess weight from mid-life onwards increases the risk of physical frailty in older age. The study tracked over 4500 participants and found that obesity and high waist circumference were associated with a higher risk of pre-frailty/frailty, highlighting the importance of maintaining a ...
A six-year study published in the Journal of the American Heart Association found that reducing overall calorie intake was a stronger determinant of weight change than meal timing. The research suggests that limiting total eating window during the day may not be as effective for controlling weight as previously thought.
Researchers found that impaired olfactory identification and sensitivity functions are associated with frailty, suggesting a potential biomarker for predicting frailty and unhealthy aging. The study's findings suggest screening older adults' ability to smell various scents could be as important as testing hearing and vision.
A collaborative study between University of Galway and Brunel University London found that patients with severe obesity respond differently to a dietary weight loss programme based on their genes. The research identified a
A study of 159 consultations between doctors and patients with obesity found that weight loss advice was rarely effective and mostly consisted of generic tips like eating less and being more active. Doctors often offered unsupported guidance and stigmatizing stereotypes, hindering patient progress.
A randomized controlled trial found that a low-carbohydrate, high-fat diet helped patients with type 2 diabetes achieve better weight loss and glucose control over a 6-month intervention compared to a high-carb, low-fat diet. However, changes were not sustained 3 months after the intervention.
A large longitudinal study found that weight-loss surgery significantly reduces urinary incontinence episode frequency in adults with severe obesity. After seven years, improvements persist despite some weight regain, offering a durable benefit to patients.
Researchers at Karolinska Institutet discovered that SARS-CoV-2 infection triggers blood vessel formation in fat tissues, leading to thermogenic metabolism and significant weight loss. Blocking this process with an antiangiogenic drug restored weight loss in mice and hamsters infected with the virus.
A new study shows that paying cash to people with obesity for losing a specific amount of weight works better than offering free tools like weight-loss programs and wearable fitness trackers. Incentives tied to actual weight lost were most effective in the short term, while goal-focused financial rewards performed better in the long run.
A recent clinical trial found that the Green Mediterranean diet reduced visceral adipose tissue by 14%, outperforming both the traditional Mediterranean diet and a healthy diet. The new diet incorporates dietary polyphenols and lower red meat intake, resulting in significant weight loss benefits.
A new study from the University of South Australia found that eating 30-50 grams of almonds can help people cut back on kilojoules consumed each day. This leads to a reduced energy intake by 300 kilojoules, mostly coming from junk food.
Researchers at the University of Ottawa have discovered that patients with electrolyte abnormalities are twice as likely to be diagnosed with an eating disorder. This study analyzed Ontario health data between 2008 and 2020, identifying a potential preventative treatment for approximately 1 million Canadians.
Rates of complications, death, and subsequent surgery were similar for gastric bypass and sleeve gastrectomy in adolescents with severe obesity. Adolescents who underwent sleeve gastrectomy had lower emergency room visits and hospital admissions compared to those who had gastric bypass surgery.
A randomized controlled trial found that both total ankle replacement and ankle fusion improve quality of life and have similar clinical scores in patients with end-stage ankle osteoarthritis. However, TAR is associated with greater wound-healing complications and nerve injuries, while AF is linked to more blood clots and nonunion of t...
A new study found that intermittent fasting is associated with disordered eating behaviors, including binge-eating and compensatory behaviors like vomiting and compulsive exercise. The study analyzed data from over 2,700 adolescents and young adults and found that 47% of women, 38% of men, and 52% transgender or gender non-conforming i...
A new study published in the New England Journal of Medicine found that semaglutide, an approved obesity drug for adults, also helps adolescents with obesity lose weight and have healthier hearts. After 68 weeks, 72.5% of participants who received semaglutide had achieved at least 5% weight loss compared to just 17% on placebo.
A new study from the University of Vermont found that TikTok's most viewed content on food, nutrition, and weight promotes a toxic diet culture, with weight loss and thinness glorified. The study highlights the need for critical thinking skills and a radical rethinking of how we relate to our bodies, food, and health.
Researchers evaluated 116 adults' diets and found most underestimated their own diet quality, with a significant gap between self-assessment and objective measurements. The study suggests that people trying to lose weight or health professionals should provide concrete information on improving diet quality.
A new study published in the Obesity journal surveyed nearly 2,500 WeightWatchers members who lost an average of almost 58 pounds and kept it off for over 3.5 years. The study found that individuals who successfully maintained weight loss resumed efforts responsively after showing limited gains and used coping skills to get back on track.
A 6-month randomized clinical trial found that a low-carbohydrate diet intervention resulted in larger reductions in hemoglobin A1c (HbA1c) levels compared to usual diet among adults with elevated untreated HbA1c. The study suggests that this dietary approach may be useful for preventing and treating type 2 diabetes.
A study published in Science Advances reveals that physical exercise triggers a neuromuscular circuit that links the production of interleukin-6 to muscle fat breakdown. This circuit is crucial for weight loss and has significant implications for obesity treatment.
A study of obese women on the 'warrior diet' found no significant change in sex-binding globulin hormone levels but a moderate drop in dehydroepiandrosterone (DHEA) levels, linked to reduced breast cancer risk. Women also experienced weight loss and improved insulin resistance.
Researchers from University of South Australia found that porous silica can prevent fats and carbohydrates from being adsorbed in the body. Engineered particles of purified sand are designed to soak up digestive enzymes, fats, and sugars within the gastrointestinal tract.
The new guidelines, issued by the American Society for Metabolic and Bariatric Surgery (ASMBS) and the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO), recommend metabolic and bariatric surgery for individuals with a BMI of 35 or more, regardless of obesity-related conditions. The guidelines also endo...
The American Gastroenterological Association releases new guidelines recommending medications paired with lifestyle changes for adults struggling to lose weight. The guidelines highlight the importance of treating obesity as a biological disease, reducing health complications like diabetes and fatty liver.
A team of researchers has identified specific neurons in the amygdala that drive mice to eat fatty or sugary foods, even when not hungry. Switching off these neurons reduced overeating and protected against obesity, while also boosting physical activity and improving metabolic health.
A study published in Neurology found that people with Parkinson's disease who gained weight had slower declines in thinking skills compared to those who lost weight. Weight management may play a crucial role in slowing cognitive decline in early Parkinson's.
The event will cover various topics including microbiota dysbiosis, oral and vaginal microbiota, and their impact on diseases like depression, cancer, and respiratory infections. The meeting aims to accelerate Microbiota medicine applications through strategic discussions.
A cohort study of nearly 200,000 people found that intentional weight loss reduces the risk of type 2 diabetes for those who are overweight or obese. However, for lean individuals, weight loss attempts are associated with longer-term weight gain and higher risks of type 2 diabetes.
A UK trial found that 70% of people with normal weight and type 2 diabetes entered remission by losing around 10% of their body weight, supporting the concept of a personal fat threshold. The study showed that even though participants had normal BMI, they had higher levels of fat in their liver and pancreas than healthy controls.
A study by researchers from UTHealth Houston and the University of Miami found that adolescents with severe obesity who underwent bariatric surgery before age 22 lost significant weight and experienced complete remission of comorbidities such as diabetes, asthma, and elevated lipids. The study's results show that these young patients c...
A randomized clinical trial found that protein restriction diets can lead to weight loss, improved blood sugar and lipid levels, and controlled blood pressure. The study involved 21 patients with metabolic syndrome, who were given either a calorie or protein restriction diet for 27 days.
A 12-month video-based weight loss programme has shown significant improvements in metabolic health and dietary behaviour among children with obesity. The study, presented at the European Society for Paediatric Endocrinology Meeting, found that participants lost weight and made better food choices.
Children with obesity who lose weight show increased hunger-related brain activity, despite changes in gut hormone levels. This disconnect may underlie why many people regain weight after a strict diet, highlighting the need for targeted treatments.
For seven years after bariatric surgery, participants showed clinically important improvements in pain levels, physical function, and work productivity, with some backsliding over time. The study found durable effects on walking speed, fitness, and most metrics of pain, even among older adults.
Weekly injections of semaglutide reduce type 2 diabetes risk by over 60%, mirroring significant weight loss. Sustained treatment is necessary to maintain the benefit.
A new study identified distinct metabolic profiles in women with Idiopathic Intercranial Hypertension (IIH), a condition characterized by raised brain pressure. Weight loss programs showed positive effects on results, suggesting that metabolism plays a role in disease development.
Researchers found that early weight loss is strongly associated with short and medium-term success in weight management programmes. Those who fail to lose at least 0.5% of their body weight after three sessions are unlikely to succeed. The threshold of failing to achieve 0.5% body weight loss was 95% accurate at identifying participant...
A study suggests that adopting the DASH diet may have the greatest impact on reducing cardiovascular disease among people with stage 1 hypertension. The research estimates that this lifestyle change could prevent 15,000 heart disease events among men and 11,000 among women.
A recent study published in Arthritis & Rheumatology found that losing weight can help combat the structural defects of knee osteoarthritis. Researchers analyzed data from over 9,683 knees and discovered a significant association between reduced body mass index (BMI) and lower incidence and progression of knee osteoarthritis.
A UBC Okanagan study found that commercial weight management programs are more effective than DIY approaches in helping people lose weight. Participants who used a commercially available program lost over twice as much weight and had better success rates, including improved blood pressure and waist circumference.
A study found that overweight patients are more inclined to disagree with their healthcare providers on weight loss and lifestyle advice. Disagreement was particularly pronounced for advice given by doctors on weight and lifestyle issues, with overweight patients more likely to disagree.
A new international study suggests that dog owners who spend more time exercising themselves tend to exercise their dogs more, leading to a perceived ideal body weight. The study found that feeding practices play a main role in owner perception of their dog being overweight, while exercise practices are crucial for an ideal weight.
Researchers found that adults with low blood urate levels are more likely to have low skeletal muscle mass and strength. This association is also linked to a higher risk of early death, particularly due to weight loss and adverse body composition.
A new study suggests that exercise training is crucial for individuals with diet-resistant obesity, improving skeletal muscle metabolism and enhancing weight loss capacity. The research challenges the one-size-fits-all approach to treating obesity and has the potential to help reshape the science of weight-loss programs.
A multisite clinical trial will deliver behavioral interventions to over 1,000 adults aged 50 and older with excess weight and cardiometabolic risk factors. The adaptive treatment model tests an evidence-based video program against a program with problem-solving therapy delivered via videoconferencing.
A new study found that a fully-automated online behavioral obesity treatment program led to significant weight loss among participants, with an average 12-week weight loss of 5.10%. The program addressed barriers in primary care, including limited resources and overburdened providers.
A study published in Cell Metabolism found that healthy underweight individuals had lower food intakes and lower activity levels, yet surprisingly higher-than-expected resting metabolic rates linked to elevated thyroid hormones. These findings contradict previous assumptions about metabolism in low BMI individuals.
A new analysis led by University of Pittsburgh School of Public Health epidemiologists found that adults who undergo bariatric surgery are more than twice as likely to get married within five years. Conversely, married patients who receive bariatric surgery are more than twice as likely to get divorced.
Researchers found wearable activity trackers encourage users to walk up to 40 minutes more each day, resulting in a significant weight loss of 1kg over five months. The study, which reviewed almost 400 studies involving 164,000 people, also found benefits for blood pressure and cholesterol levels.
The proportion of healthy-weight young people trying to shed pounds in England has nearly tripled from around 1 in 20 to nearly 1 in 7 over 20 years. Reported slimming attempts among all children, particularly those who are overweight and obese, have shot up, surpassing the rise in excess weight gain and service provision.
A study by the University of Illinois at Urbana-Champaign found that an individualized diet program can help people lose extra pounds and keep them off. The program uses easy-to-use tools to empower dieters to make informed choices about their food intake.
Researchers found that healthy underweight individuals consume 12% less food and are 23% less active than those with normal BMIs. They also have higher resting metabolic rates, suggesting that low body fat may trump physical activity in downstream consequences.
UTSW researchers found that triptan migraine drugs can decrease appetite and lead to weight loss in obese mice. The study suggests a potential repurpose of these drugs for obesity treatment.
Eating more protein during weight loss helps avoid lean mass loss and promotes healthier eating habits, according to a Rutgers study. The study found that higher protein intake is associated with increased green vegetable consumption, reduced refined grain and sugar intake, and improved retention of lean muscle mass.
A narrative review of endoscopic sleeve gastroplasty (ESG) highlights its potential as a minimally invasive weight loss procedure. The review concludes that ESG induces significant weight loss and improves obesity-related conditions, with the technique's success attributed to delayed gastric emptying. Researchers support the use of ESG...
A new pediatric obesity program, Guided Self-Help (GSH), was developed to provide a less intensive and more accessible way to treat childhood obesity. The study found that GSH was similarly effective as traditional Family-Based Treatment (FBT) in supporting pediatric weight loss, but with higher attendance rates.