Articles tagged with Weight Loss
A new study suggests that a diet high in protein, zinc, and niacin, and low in saturated fat, can improve blood vessel flexibility. The study found improvements in metabolic and cardiovascular health, including reductions in calorie and saturated fat intake, increases in zinc and niacin, and improvements in blood vessel function.
A UK study of over 400,000 adults with obesity found that losing weight reduces the risk of 13 obesity-related complications, with greater benefits for those with lower initial BMIs. Weight gain increases these risks, particularly in individuals with lower starting BMIs.
Canadian and German researchers have identified personalized prescriptions that combine drugs to treat obesity and Type 2 diabetes. The combination therapy shows higher effectiveness in some patients and fewer side effects compared to single drugs. Studies are now needed to understand why individuals respond differently to the treatment.
A study published in Obesity found that two specific brain networks, FN1 and FN2, are strongly linked to weight loss success. The neural circuits involved sensory and motor skills (FN1) and self-regulation and attention (FN2).
Researchers will enroll 1,000 adults in a placebo-controlled trial to assess the effects of low-cost phentermine on weight loss and related health metrics over two years. The study aims to provide long-term treatment options for patients struggling with obesity.
An automated nutrition app called eNutri improved participants' healthy diet scores by 6% compared to a control group. The app provides personalized nutrition advice based on evidence and uses a diet scoring system.
A study suggests that intense exercise can help rats resist cues for high-fat food pellets, even after a 30-day diet. The researchers found that exercise modulated the rats' willingness to work for these cues, reflecting their craving level.
A study published in Current Biology found that consuming non-essential amino acids can curb appetite and encourage physical activity in mice. This mechanism is thought to be rooted in evolutionary history, where eating these amino acids promoted the urge to seek out more nutrient-rich food sources.
The 9th World Congress on Targeting Microbiota 2022 will focus on recent advances in the microbiota field and therapeutic strategies. Key findings include research on probiotic strains, natural mineral waters, and extracellular vesicles.
Researchers found that fighters who rapidly cut weight before bouts are more likely to suffer concussions or be misdiagnosed with head trauma. The study also discovered that the practice may not offer a competitive advantage and can leave fighters at a disadvantage more often than not.
A new study published in Surgical Endoscopy found that adolescents with obesity who underwent laparoscopic sleeve gastrectomy benefited from reduced obesity and concomitant organ damage, regardless of their age at the time of surgery. Additionally, adolescents with a family history of bariatric surgery had a higher weight prior to weig...
A study published in the Journal of Cachexia, Sarcopenia and Muscle found that BAM15 improves health outcomes for aged mice with obesity by preventing muscle loss and increasing energy expenditure. The compound helped mice lose fat, gain strength and increase physical activity.
A new study from Northwestern University found that once-weekly prednisone treatment improved exercise endurance, increased lean body mass, and reduced weight in obese mice. The treatment also promoted nutrient uptake into muscles and increased adiponectin levels, a hormone that helps protect against diabetes and insulin resistance.
A new study suggests that dramatic swings in food intake can have long-term impacts on cardiovascular health and metabolism. Researchers found that rats who experienced cycles of weight loss and gain had reduced heart and kidney function, as well as increased insulin resistance.
A large cohort study found that babies born to men who took metformin during sperm development were at increased risk for genital defects in boys. Diabetes control affects sperm quality, so men should discuss alternative treatments with their doctors before conception. The findings suggest a need for further study on treatment of prosp...
The Experimental Biology (EB) 2022 meeting features live presentations and a moderated Q&A session on groundbreaking studies. The virtual press conference reveals potential treatments for Parkinson's disease, COVID-19 vaccine-associated side effects, and alleviating food allergies.
This year's Experimental Biology 2022 meeting features groundbreaking studies on COVID-19 vaccine-associated symptoms in non-menstruating people, a plant compound showing promise for alleviating food allergies, and the potential of omega-3s to boost immunotherapy's cancer-fighting power. Researchers also explore the safety of using CBD...
Intermittent fasting produces mild to moderate weight loss and improves cardiometabolic risk factors, comparable to traditional calorie-restricted diets. The review also dispels myths about intermittent fasting, including the misconception that it leads to weakness and decreased concentration.
A randomized study of 379 women with obesity and unexplained infertility found that intensive lifestyle changes that shed pounds led to no better chances of pregnancy than simply increasing physical activity without weight loss. The study also showed significant health benefits from weight loss, including a decrease in metabolic syndrome.
The green Mediterranean diet induces specific microbial changes in the gut microbiome, enriching with bacteria that positively affect glucose metabolism and insulin sensitivity. This novel diet also promotes genetic pathways involved in reducing branched-chain amino acids linked to insulin resistance.
A new analysis by University of Copenhagen researchers found that a Nordic diet has positive health benefits regardless of weight loss. The diet's unique fat composition, high in omega-3 and omega-6 unsaturated fats, plays a significant role in lowering blood sugar and cholesterol levels.
A new study from the University of South Australia has found that popular weight loss diets can be expensive, with costs ranging from $345 to $625 per week. The most cost-effective diet was modelled on the Australian Guide to Healthy Eating and adapted for weight loss through calorie restriction.
A new study found that an anti-tumor drug, camptothecin, can activate a natural hunger-suppressing pathway in mice, leading to significant weight loss. The mechanism involves the elevation of growth differentiation factor 15 (GDF15), which suppresses food intake and reduces body weight.
A recent commentary argues that treating obesity should prioritize compassionate care and focus on health rather than weight. The researchers aim to eliminate the false dichotomy between eating and weight disorders, promoting a patient-centered approach that screens for and addresses eating disorders throughout treatment.
Exercise interventions delivered in primary care appear to boost moderate to vigorous intensity activity by an average of 14 minutes a week. Participants also weighed 1 kg less than controls at follow-up, highlighting the critical role of primary care professionals in promoting healthy behavior changes.
A study published in Obesity found that telemedicine can mitigate barriers to obesity care, including limited access to specialized care and high costs. Virtual interactions between patients and healthcare providers may be more cost-effective and lead to better weight loss outcomes.
A new study reveals that middle-aged men perceive weight gain as an inevitable consequence of family and career commitments. The research found that these men experience low self-worth and despondency, despite awareness of health risks, due to a lack of education on nutrition and lifestyle factors.
A new study published in JAMA Network Open suggests that gastric bypass surgery is the most effective treatment option for patients with severe obesity and type 2 diabetes, leading to greater weight loss and a higher rate of remission. The study found that gastric bypass produces better results regardless of diabetes severity.
A study found that rapid weight gain from antipsychotic medications can contribute to loss of agency, hope, and social withdrawal. Understanding this psychological journey may offer new targets for weight loss treatments.
Researchers analyzed the motivations and strategies of over 6,000 long-term weight-loss maintainers, finding that perseverance, consistently tracking food intake, and focusing on health goals were key to success. The study's findings may lead to new approaches in counseling and lifestyle interventions.
A new study found that increasing sleep duration by an average of 1.2 hours per night reduced participants' overall caloric intake by an average of 270 kcal per day. This translates to roughly 12 kg, or 26 lbs., of weight loss over three years if the effects were maintained.
A new study finds that weight loss is associated with a 46% reduced risk of developing colorectal adenoma. Adults who are initially overweight or obese may be able to reduce their risk by losing weight, while weight gain increases the chance of developing adenoma.
A recent study published by The Obesity Society found that metabolic adaptation after weight loss increases the time necessary to achieve weight-loss goals in premenopausal women. The study, which included 65 participants, revealed a significant delay in achieving weight-loss goals due to metabolic adaptation.
Scientists at Nanyang Technological University have developed a novel therapeutic approach to tackle obesity, reducing body fat and improving blood markers through a hydrogel injection and near infrared light treatment. The treatment shows significant promise in lab trials, with mice experiencing reduced body mass and improved metabolism.
A 24-week study found that dogs fed a reduced calorie, high-protein, high-fiber diet achieved healthier weight without losing muscle mass. Their serum triglycerides, insulin, and inflammatory markers decreased with weight loss.
A new study published in Cell Reports Medicine found that a cancer drug called ADI-PEG 20 improved insulin sensitivity, cholesterol levels, and reduced inflammation in mice. The treatment also caused significant weight loss in obese mice, suggesting potential benefits for human obesity treatment.
A new interdisciplinary treatment method has shown significant improvements in reducing overeating episodes and emotional issues among individuals with morbid obesity. The treatment combined mental health care with somatics, resulting in a nearly 30% reduction in overeating episodes and improved emotional well-being.
A study of nearly 12,000 obese patients found that substantial weight loss achieved through weight loss surgery was associated with improved outcomes after contracting COVID-19, including lower risk of severe disease. The results suggest that weight loss surgery may help mitigate the severity of COVID-19 in individuals with obesity.
A Cleveland Clinic study found that prior weight loss achieved with bariatric surgery was associated with a 60% lower risk of developing severe COVID-19. Patients who underwent weight-loss surgery had better clinical outcomes, including reduced hospitalization and need for supplemental oxygen.
A new study found that incorporating frequent periods of enjoyable movement into daily life leads to better short-term and long-term weight loss compared to structured exercise. The intervention, which encouraged participants to move more often throughout the day, resulted in similar weight loss and improved maintenance relative to a h...
A new study found that news media amplified rather than rectified misleading health information from TV personality Dr. Oz, resulting in the further spread of misinformation. The researchers called for government oversight to lessen the risk of spreading inaccuracies.
Researchers at University of California - Riverside are studying the keto and intermittent fasting diets on a molecular level, finding that women may metabolize fat differently than men. The study aims to understand why keto diet may not be effective for women and how it affects their overall health.
A University of Gothenburg study found that bariatric surgery lowers cancer risk by 60% in obese patients with type 2 diabetes, particularly those achieving and maintaining normal glucose control. The research highlights the importance of glucose control in preventing cancer in this high-risk population.
A new study found that consuming prunes can help regulate appetite and lead to greater weight loss compared to other snack choices. Prune consumption was also associated with improved satiety and reduced hunger levels, making them a potential strategy for managing holiday cravings.
Researchers found that video-based, telehealth-delivered exercise and weight loss programs improved pain and function in people with knee osteoarthritis and overweight or obesity. The intervention with dietary component led to substantial weight loss and additional benefits.
A new study published in Medicine & Science in Sports & Exercise found that exercising intensely at the start of a fast can maximize health benefits by speeding up the transition to ketosis. Participants who exercised reached ketosis on average three and a half hours earlier, producing 43% more B-hydroxybutyrate.
A new study found that low energy diets with formula meal replacements are the most effective methods for weight management and remission in adults with type 2 diabetes. Formula meal replacements achieved greater weight loss compared to food-based low-energy diets.
A clinical trial found that long-term weight loss was similar for those who received 5:2 diet or standard weight management advice, with 18% and 15% of participants losing at least five per cent of their body weight. However, the 5:2 diet group was more likely to recommend the intervention to others or continue with it.
New research from the University of South Australia finds that the 5:2 diet is just as effective as a continuous energy-restricted diet in achieving weight loss and preventing type 2 diabetes in women with a previous diagnosis of gestational diabetes. The study suggests that this diet offers greater choice and flexibility for women loo...
A recent study by the University of California - San Diego team discovered that glycogen regulates and promotes fat metabolism, helping to balance energy intake and expenditure. The research suggests modulating glycogen metabolism in fat cells could provide new approaches for weight loss and improved metabolic health.
About 42% of U.S. adults are considered clinically obese due to increased risk of health conditions such as diabetes and heart disease. New weight-loss drugs like Wegovy (semaglutide) show promise in safely aiding weight loss, but long-term side effects and sustainability remain concerns.
The MUSC Hollings Cancer Center researchers are exploring the role of macroenvironment in pancreatic cancer-induced cachexia to address this debilitating condition. The team aims to provide new biological insight, which will be coordinated by four cores within the program project grant.
A clinical trial found that a green Mediterranean diet rich in leafy greens like Mankai and green tea can elevate fasting ghrelin levels, reducing belly fat and improving insulin sensitivity. This approach may also have additional cardiometabolic benefits.
A review of 25 studies on intermittent fasting found that all forms produced mild to moderate weight loss, similar to traditional calorie-restrictive diets. Intermittent fasting regimens also showed benefits in decreasing blood pressure and insulin resistance, and improving appetite regulation.
Researchers found that eating high-fibre whole grain rye products resulted in greater weight loss and body fat reduction compared to refined wheat alternatives. The study, involving 242 participants, suggests that rye's unique fibre content may contribute to its weight-loss benefits.
Researchers found that young male winter swimmers had better thermoregulation and higher heat loss due to frequent sauna exposure. They also showed increased brown fat tissue activity, particularly in response to cold exposure.
A new study finds that bariatric surgery increased among lower-income white adults, but remained unchanged for Hispanic and Black adults following Medicaid expansion. The increase in weight-loss surgery rates is a significant finding with implications for health policy.
A recent study by Michigan Medicine found that sleeve gastrectomy is associated with lower risks of death and complications compared to gastric bypass surgery. However, patients who underwent sleeve gastrectomy were more likely to require follow-up surgery.
Cachexia is characterized by weight loss and muscle tissue shrinkage, driven by the immune system's response to chronic infections and diseases. Researchers from CeMM emphasize the need for more research into cachexia, highlighting the importance of interplay between the immune system and metabolism.
A multidisciplinary taskforce developed a Clinical Care Pathway for NAFLD/NASH, outlining practical guidance from screening to patient care management. The pathway aims to provide efficient, safe, and value-based care for patients with NAFLD and NASH, highlighting the importance of early interventions and shared decision-making.