A recent study at UC Irvine found that semaglutide medication can lead to significant weight loss and reduce cardiovascular risk in 93 million U.S. adults. The medication may prevent up to 1.5 million heart attacks and strokes over 10 years, resulting in 43 million fewer obese people.
The study of 18.4 million patients indicates a low annual probability of 5% or greater weight loss, but a higher likelihood of BMI reduction to the healthy weight category, especially among those with high initial BMIs.
A randomized clinical trial found that telephone-based cognitive behavioral therapy (tele-CBT) significantly reduced binge eating, emotional eating, and depression/anxiety symptoms in individuals after bariatric surgery. However, short-term weight outcomes were unaffected by tele-CBT.
A world-first study from the University of South Australia exposes the real weight gains of everyday Australians, finding that weight fluctuates throughout the year. The study highlights the importance of targeting temporal hot spots to curb unhealthy weight fluctuations and prevent unwanted weight gain.
A Northwestern University study found that only 60% of women with heart disease risk factors received counseling on optimizing their heart health during their six-week postpartum visit. The study highlights the need for improved access to care and increased awareness of maternal cardiovascular health monitoring.
A randomized controlled study found that participants who restricted their daily eating to between noon and 8 p.m. lost more weight and showed similar improvements in blood sugar levels compared to those on a calorie-restricted diet.
Researchers developed a tailored approach to weight loss and cardiometabolic risk factors, showing significant improvement in targeted areas like abnormal fullness and emotional eating. The study suggests the need for an actionable, phenotype-based classification of patients in obesity treatment, moving beyond reliance on scales or bod...
A new study found that social media platforms like TikTok and Instagram are ideal spaces to educate and guide US youth of color on healthy weight management. Nearly 1 in 4 adolescents experienced obesity from 2017 to 2020, with youths of color experiencing disproportionately higher rates.
A new study from Aarhus University reveals that female athletes who consume too little energy through their diet in comparison to their training volume experience negatively impacted muscles' ability to respond to training. The study shows that insufficient energy intake can lead to changes in the hormonal system, including a decrease ...
A recent international study of over 745,000 adolescents from 41 countries found a decrease in those who overestimate their weight and an increase in those who underestimate it. This shift could reduce the effectiveness of public health interventions aimed at weight reduction in young people, as they may make unhealthy lifestyle choices.
A new $7 million study at Wake Forest University is investigating the impact of resistance training, bone-loading exercises, and osteoporosis medication on bone health in older adults who are losing weight. The study aims to determine whether these interventions can help preserve bone mass and reduce fracture risk.
Research from University of Illinois Chicago found water fasts spur noticeable short-term weight loss, but metabolic benefits disappear soon after fast ends. Participants lost 4-10% of their weight during the fast, and some gained back the lost weight within three months.
Researchers have uncovered a key mechanism for promoting weight loss and maintaining energy burn during dieting, thanks to the hormone GDF15. This discovery opens new possibilities for helping people maintain weight loss after dieting.
A 12-year study by Pennington Biomedical researchers found that metabolic surgery provides better results, less regression, compared to medical or lifestyle intervention for patients with class 1 obesity. The study showed significant improvements in glycemic control and weight loss, with high rates of diabetes remission.
Researchers found that restricting methionine intake via a low-methionine diet or oral administration of recombinant methioninase-producing E. coli reversed old-age-induced obesity in mice, leading to significant weight loss after just 14 days.
A new study found that higher doses of oral semaglutide improved regulation of blood sugar levels and weight loss compared to lower doses. Participants who received the 25mg and 50mg doses lost an average of 17.5 pounds, nearly twice as much weight loss as those who took the lowest dose.
A randomized controlled trial found that time-restricted eating produced similar weight loss results to traditional calorie counting in a racially diverse population of adults with obesity. Participants who engaged in 8-hour time-restricted eating had improved insulin sensitivity compared to those in the control group.
Research suggests that aromatase inhibitors can limit the effectiveness of weight loss medications in breast cancer survivors. Studies have shown that these medications are less effective in women taking aromatase inhibitors, leading to reduced weight loss and increased risk of health complications.
A study published in Radiology found that weight-loss surgery, specifically sleeve gastrectomy, has negative effects on bone health in adolescents and young adults. The procedure led to an increase in bone marrow fat and a decrease in bone density, suggesting potential long-term consequences for bone health and fracture risk.
A retrospective analysis of national data found that over 20 million Americans experienced loss of smell or taste after COVID infection, with a large portion never fully recovering these senses. The study estimated that almost 28 million Americans may be left with decreased sense of smell after COVID infection.
Researchers found that participants only need to track around 30% of the days to lose more than 3% weight and 40% of the days to lose more than 5% weight. A third group, called the low trackers, started tracking only three days a week, and dropped to zero by three months, where they stayed for the rest of the intervention.
A new study suggests that sabotage, collusion, and 'feeding' behaviors from loved ones can undermine weight loss attempts. Researchers found these negative social support mechanisms can erode confidence and self-esteem.
Researchers found that a reduction in body weight of 1% led to participants' brain age being almost 9 months younger than expected. This attenuation of brain aging was associated with changes in liver fat and enzymes, which can negatively affect brain health in Alzheimer's disease.
A clinical trial found that a telephone-based weight loss program can help breast cancer patients with overweight or obesity lower their weight by a significant degree. Women who received the program lost an average of 4.8% of their baseline body weight, compared to a 0.9% increase in the control group.
Researchers found that focusing on satiety and satiation through the consumption of fruits and vegetables can lead to better weight loss outcomes. Both diet programs increased levels of satiation and satiety among participants, as well as promoting better quality of life and emotional well-being.
A new weight loss tool called PATHWEIGH was developed to address clinician barriers in providing patient care that addresses weight. The tool has shown early success and has been implemented in a health system's primary care clinics, improving weight management efforts among patients with obesity.
Teenagers living with obesity who experience uncontrolled hunger are more likely to perceive their weight as negative, worried about its health effects, and actively trying to lose weight. They also report greater dissatisfaction with their body image and higher rates of bullying.
A multicentre, one-year real-world study found semaglutide effective for weight loss in patients with overweight and obesity, with 82% losing over 5% body weight. The medication also improved metabolic parameters, including blood pressure and cholesterol levels.
A new analysis of the SURMOUNT-1 study shows that tirzepatide improves body composition across a range of adult age groups, with significant reductions in fat mass. The treatment also results in a clinically meaningful improvement in body composition, with only one-quarter of weight lost being lean mass.
A Dutch study found that individuals who feel safe in their neighborhoods lose more weight during lifestyle interventions. Those with higher scores on a safety scale experienced greater decreases in weight and waist circumference, regardless of sex, age, or education level.
Researchers at Koc University have identified a novel molecular mechanism that can slow down or block muscle wasting in cancer patients. The activation of EDA2R signalling promotes skeletal muscle atrophy, and deleting either EDA2R or NIK enzyme can protect the organism from muscle loss.
A new study found that ear acupuncture with beads can help reduce waist circumference, body fat, and BMI in men living with obesity. Participants who received auricular acupuncture with beads lost an average of 10.4cm off their waist circumference and 4% of total body fat.
A new treatment combining a swallowable gastric balloon with the anti-obesity drug liraglutide is safe and effective for boosting weight loss. Participants lost an average of 19% of their initial body weight and reduced BMI by 4.5kg/m2 after 8 months of treatment.
A study of 307,000 neonates with very low birth weight found that increased use of probiotics in hospitals was associated with reduced risk of necrotizing enterocolitis, but not sepsis or mortality rates. The adoption of routine probiotic use increased slowly from 2012 to 2019.
A new study from University of Michigan suggests that the perception of not enough food can be sufficient to slow aging in flies. The researchers induced hunger in flies through various methods, including altering amino acid levels and using optogenetics, and found that these flies lived significantly longer than controls.
A new study published in JMIR Diabetes found that Fitterfly's diabetes digital therapeutics program improved glycemic control and weight management in participants with type 2 diabetes. The 90-day program led to significant reductions in hemoglobin A1c levels and body weight.
A specialized weight loss program for Deaf people, designed and led by Deaf individuals, resulted in significant weight loss among participants. The Deaf Weight Wise program focused on lifestyle changes, social support, and cultural relevance, leading to a higher retention rate and better outcomes compared to mainstream programs.
The 'Low Oxygen and Weight Status' study will investigate the effects of low oxygen levels on weight loss and health outcomes in adults with obesity. Participants will be randomized to sleep in an altitude tent or normal conditions, while following a weight loss diet. The study aims to inform new strategies for improving metabolic health.
Researchers at West Virginia University found that bariatric surgery significantly reduces the risk of major cardiovascular events and death in patients with NAFLD. The study included 9,374 adult patients with NAFLD and obesity, who underwent either Roux-en-Y gastric bypass or sleeve gastrectomy.
Researchers analyzed data from over 20,000 US adults, finding that those who lost at least 5% of their body weight showed higher diet quality and more moderate physical activity. However, the study also found that many individuals relied on unsustainable non-evidence-based approaches for weight loss, highlighting the need for a paradig...
The American Heart Association scientific statement rates how closely popular dietary patterns align with its guidance for heart-healthy eating. The statement evaluates 10 categories of diets, scoring them from 31 to 100 based on their alignment with the guidance, with some diets receiving high scores while others need improvement.
A new study found that unintentional weight loss is grossly under-recognized in primary care, with only 21% recognized by doctors. The researchers recommend using electronic health record alerts to prompt clinicians to ask about intentional or unintentional weight loss, which can be a sign of a serious underlying condition.
A comprehensive review of 169 clinical trials found that the effect of fructose-containing sugars on adiposity varies among food sources and energy control. High doses of certain sources, like SSBs, lead to increased body weight, while others, such as fruit and honey, show moderate beneficial effects when consumed in moderation.
A recent study published in Life Metabolism reveals that weight loss increases skeletal muscle mitochondrial energy efficiency in obese mice. This increase leads to reduced energy expenditure throughout the body, contributing to weight loss rebound.
A new study published in Metabolism reveals that the hormone neurotensin is released in greater amounts by people who successfully maintain weight loss after a low-calorie diet. This suggests that neurotensin may play a key role in regulating appetite and weight management.
A new study published in Proceedings of the Royal Society B found that time-restricted fasting affects reproduction differently in male and female zebrafish. After returning to normal food consumption levels, females increased offspring production at the cost of reduced egg quality, while male sperm quality also decreased.
A study published in Diabetologia found that bariatric surgery can regenerate damaged nerves and improve metabolic risk factors related to diabetes. Peripheral neuropathy, a condition affecting over 30 million Americans, showed improvements two years after the procedure.
Exposure to female odours causes weight loss and extends the life spans of mice, potentially influencing human metabolism and ageing. The study found that male mice exposed to female odours experienced increased energy expenditure and reduced body fat levels.
A new class of compounds reduces weight dramatically and lowers blood glucose in lab animals, boosting calorie burn and avoiding nausea. The injectable treatments activate multiple gut hormone receptors, including GLP-1 and PYY, to signal fullness and curb appetite.
Research highlights that intensive behavioral weight loss programs significantly reduce cardiovascular disease and Type 2 diabetes risk factors, which persist for at least five years. Participants who lost weight through such programs had lower risk factors compared to those in less intensive or no weight loss programs.
A new survey found that nearly a third of Americans worry more about obesity due to COVID-19, with 28 million people considering weight loss methods. The survey also showed that nearly 90% with obesity have tried to lose weight at some point in their lives, but many underestimate the effectiveness of treatments like weight-loss surgery.
A new study published in the European Heart Journal shows that using waist-to-height ratio instead of BMI provides a clearer picture of patient outcomes in heart failure. The researchers found that greater adiposity is associated with worse outcomes, including high rates of hospitalization and reduced health-related quality of life.
Cases of Candida auris, a highly contagious fungal infection, rose drastically between 2019 and 2021, with an increase in echinocandin-resistant cases. The findings emphasize the need for improved detection and infection control practices to prevent the spread of C auris.
Studies found an association between living close to higher-quality food stores and better weight loss outcomes after bariatric surgery. Living near low-diversity stores was linked to less sustained weight loss, while moderate- or high-diversity stores had no effect.
Research reveals island-dwelling mammal species face higher extinction risks, with those experiencing extreme size changes being particularly endangered. Human arrival on islands multiplies the probability of extinction by 16, contributing to a 'protracted extinction event' spanning over 100,000 years.
Preliminary research found that better sleep health was associated with higher rates of attendance at group interval sessions, adherence to caloric intake goals, and improvement in time spent performing moderate-vigorous physical activity. However, the association between sleep health and physical activity was not statistically signifi...
A new study found that eccentric contractions prove most effective in preventing muscle wasting and damage after immobilization. Strengthening the unaffected arm through weightlifting also counteracted muscle atrophy, with a stronger cross-education effect observed for eccentric contractions.
A new review paper from Mayo Clinic outlines how obesity impacts common tests used to diagnose heart disease, such as ECG, CT scan, MRI, and echocardiogram. The study highlights the need for alternative approaches to prevent weight gain in patients with heart disease.
Researchers found 21 Alzheimer's disease-related genes associated with obesity, including those linked to neuro-inflammation and amyloid-beta protein deposition. Obesity in midlife and women is more closely linked to dementia risk than late life or men.
Researchers at UTHSC are conducting a study on interactive technology to aid weight loss in overweight and obese adults. The CHAMPS program will deliver a weight loss program via internet, patient portal, text messaging, and phone calls to reduce barriers and promote significant weight loss.